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Volumn 13, Issue 4, 2017, Pages 454-467

Preclinical Alzheimer's disease: A systematic review of the cohorts underlying the concept

Author keywords

Biomarker; Clinical trial; Cognition; Cohort; Cross sectional; Familial Alzheimer's disease; Longitudinal; Neuropathology; Preclinical Alzheimer's disease; Systematic review

Indexed keywords

ALZHEIMER DISEASE; CASE CONTROL STUDY; COGNITION; COGNITION ASSESSMENT; COGNITIVE DEFECT; COHORT ANALYSIS; CONCEPTUAL FRAMEWORK; DIAGNOSTIC PROCEDURE; DISEASE MARKER; FOLLOW UP; HUMAN; INFORMATION RETRIEVAL; MENTAL DETERIORATION; NEUROPATHOLOGY; NOMENCLATURE; PATHOPHYSIOLOGY; PRECLINICAL STUDY; PRIORITY JOURNAL; REVIEW; STANDARDIZATION; SYSTEMATIC REVIEW; CLASSIFICATION; METABOLISM; PRODROMAL SYMPTOM;

EID: 85014329946     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2016.12.003     Document Type: Review
Times cited : (58)

References (74)
  • 1
    • 84962325429 scopus 로고    scopus 로고
    • Preclinical Alzheimer's disease: definition, natural history, and diagnostic criteria
    • [1] Dubois, B., Hampel, H., Feldman, H.H., Scheltens, P., Aisen, P., Andrieu, S., et al. Preclinical Alzheimer's disease: definition, natural history, and diagnostic criteria. Alzheimers Dement 12 (2016), 292–323.
    • (2016) Alzheimers Dement , vol.12 , pp. 292-323
    • Dubois, B.1    Hampel, H.2    Feldman, H.H.3    Scheltens, P.4    Aisen, P.5    Andrieu, S.6
  • 2
    • 14444285507 scopus 로고    scopus 로고
    • Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype
    • [2] Berg, L., McKeel, D.W. Jr., Miller, J.P., Storandt, M., Rubin, E.H., Morris, J.C., et al. Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 55 (1998), 326–335.
    • (1998) Arch Neurol , vol.55 , pp. 326-335
    • Berg, L.1    McKeel, D.W.2    Miller, J.P.3    Storandt, M.4    Rubin, E.H.5    Morris, J.C.6
  • 3
    • 0025289562 scopus 로고
    • Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person
    • [3] Delaere, P., Duyckaerts, C., Masters, C., Beyreuther, K., Piette, F., Hauw, J.J., Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person. Neurosci Lett 116 (1990), 87–93.
    • (1990) Neurosci Lett , vol.116 , pp. 87-93
    • Delaere, P.1    Duyckaerts, C.2    Masters, C.3    Beyreuther, K.4    Piette, F.5    Hauw, J.J.6
  • 4
    • 0025240790 scopus 로고
    • A quantitative histological study of early clinical and preclinical Alzheimer's disease
    • [4] Hubbard, B.M., Fenton, G.W., Anderson, J.M., A quantitative histological study of early clinical and preclinical Alzheimer's disease. Neuropathol Appl Neurobiol 16 (1990), 111–121.
    • (1990) Neuropathol Appl Neurobiol , vol.16 , pp. 111-121
    • Hubbard, B.M.1    Fenton, G.W.2    Anderson, J.M.3
  • 5
    • 33747054765 scopus 로고    scopus 로고
    • Longitudinal course and neuropathologic outcomes in original vs revised MCI and in pre-MCI
    • [5] Storandt, M., Grant, E.A., Miller, J.P., Morris, J.C., Longitudinal course and neuropathologic outcomes in original vs revised MCI and in pre-MCI. Neurology 67 (2006), 467–473.
    • (2006) Neurology , vol.67 , pp. 467-473
    • Storandt, M.1    Grant, E.A.2    Miller, J.P.3    Morris, J.C.4
  • 6
    • 84900988440 scopus 로고    scopus 로고
    • Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
    • [6] Dubois, B., Feldman, H.H., Jacova, C., Hampel, H., Molinuevo, J.L., Blennow, K., et al. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. Lancet Neurol 13 (2014), 614–629.
    • (2014) Lancet Neurol , vol.13 , pp. 614-629
    • Dubois, B.1    Feldman, H.H.2    Jacova, C.3    Hampel, H.4    Molinuevo, J.L.5    Blennow, K.6
  • 7
    • 79956098248 scopus 로고    scopus 로고
    • Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • [7] Sperling, R.A., Aisen, P.S., Beckett, L.A., Bennett, D.A., Craft, S., Fagan, A.M., et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7 (2011), 280–292.
    • (2011) Alzheimers Dement , vol.7 , pp. 280-292
    • Sperling, R.A.1    Aisen, P.S.2    Beckett, L.A.3    Bennett, D.A.4    Craft, S.5    Fagan, A.M.6
  • 8
    • 84947483839 scopus 로고    scopus 로고
    • Current developments in dementia risk prediction modelling: an updated systematic review
    • [8] Tang, E.Y., Harrison, S.L., Errington, L., Gordon, M.F., Visser, P.J., Novak, G., et al. Current developments in dementia risk prediction modelling: an updated systematic review. PLoS One, 10, 2015, e0136181.
    • (2015) PLoS One , vol.10 , pp. e0136181
    • Tang, E.Y.1    Harrison, S.L.2    Errington, L.3    Gordon, M.F.4    Visser, P.J.5    Novak, G.6
  • 10
    • 84897910461 scopus 로고    scopus 로고
    • Compensatory mechanisms in higher-educated subjects with Alzheimer's disease: a study of 20 years of cognitive decline
    • [10] Amieva, H., Mokri, H., Le Goff, M., Meillon, C., Jacqmin-Gadda, H., Foubert-Samier, A., et al. Compensatory mechanisms in higher-educated subjects with Alzheimer's disease: a study of 20 years of cognitive decline. Brain 137 (2014), 1167–1175.
    • (2014) Brain , vol.137 , pp. 1167-1175
    • Amieva, H.1    Mokri, H.2    Le Goff, M.3    Meillon, C.4    Jacqmin-Gadda, H.5    Foubert-Samier, A.6
  • 11
    • 84922073605 scopus 로고    scopus 로고
    • PART and SNAP
    • [11] Jack, C.R. Jr., PART and SNAP. Acta Neuropathol 128 (2014), 773–776.
    • (2014) Acta Neuropathol , vol.128 , pp. 773-776
    • Jack, C.R.1
  • 12
    • 84863185648 scopus 로고    scopus 로고
    • Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease
    • [12] Knopman, D.S., Jack, C.R. Jr., Wiste, H.J., Weigand, S.D., Vemuri, P., Lowe, V., et al. Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease. Neurology 78 (2012), 1576–1582.
    • (2012) Neurology , vol.78 , pp. 1576-1582
    • Knopman, D.S.1    Jack, C.R.2    Wiste, H.J.3    Weigand, S.D.4    Vemuri, P.5    Lowe, V.6
  • 13
    • 84912064760 scopus 로고    scopus 로고
    • Synergistic effect of beta-amyloid and neurodegeneration on cognitive decline in clinically normal individuals
    • [13] Mormino, E.C., Betensky, R.A., Hedden, T., Schultz, A.P., Amariglio, R.E., Rentz, D.M., et al. Synergistic effect of beta-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. JAMA Neurol 71 (2014), 1379–1385.
    • (2014) JAMA Neurol , vol.71 , pp. 1379-1385
    • Mormino, E.C.1    Betensky, R.A.2    Hedden, T.3    Schultz, A.P.4    Amariglio, R.E.5    Rentz, D.M.6
  • 14
    • 84902162274 scopus 로고    scopus 로고
    • Amyloid and APOE epsilon4 interact to influence short-term decline in preclinical Alzheimer disease
    • [14] Mormino, E.C., Betensky, R.A., Hedden, T., Schultz, A.P., Ward, A., Huijbers, W., et al. Amyloid and APOE epsilon4 interact to influence short-term decline in preclinical Alzheimer disease. Neurology 82 (2014), 1760–1767.
    • (2014) Neurology , vol.82 , pp. 1760-1767
    • Mormino, E.C.1    Betensky, R.A.2    Hedden, T.3    Schultz, A.P.4    Ward, A.5    Huijbers, W.6
  • 15
    • 84866300870 scopus 로고    scopus 로고
    • Subjective cognitive complaints and amyloid burden in cognitively normal older individuals
    • [15] Amariglio, R.E., Becker, J.A., Carmasin, J., Wadsworth, L.P., Lorius, N., Sullivan, C., et al. Subjective cognitive complaints and amyloid burden in cognitively normal older individuals. Neuropsychologia 50 (2012), 2880–2886.
    • (2012) Neuropsychologia , vol.50 , pp. 2880-2886
    • Amariglio, R.E.1    Becker, J.A.2    Carmasin, J.3    Wadsworth, L.P.4    Lorius, N.5    Sullivan, C.6
  • 16
    • 84903539808 scopus 로고    scopus 로고
    • The Alzheimer's prevention initiative composite cognitive test score: sample size estimates for the evaluation of preclinical Alzheimer's disease treatments in presenilin 1 E280A mutation carriers
    • [16] Ayutyanont, N., Langbaum, J.B., Hendrix, S.B., Chen, K., Fleisher, A.S., Friesenhahn, M., et al. The Alzheimer's prevention initiative composite cognitive test score: sample size estimates for the evaluation of preclinical Alzheimer's disease treatments in presenilin 1 E280A mutation carriers. J Clin Psychiatry 75 (2014), 652–660.
    • (2014) J Clin Psychiatry , vol.75 , pp. 652-660
    • Ayutyanont, N.1    Langbaum, J.B.2    Hendrix, S.B.3    Chen, K.4    Fleisher, A.S.5    Friesenhahn, M.6
  • 17
    • 84912143249 scopus 로고    scopus 로고
    • The evolution of preclinical Alzheimer's disease: implications for prevention trials
    • [17] Sperling, R., Mormino, E., Johnson, K., The evolution of preclinical Alzheimer's disease: implications for prevention trials. Neuron 84 (2014), 608–622.
    • (2014) Neuron , vol.84 , pp. 608-622
    • Sperling, R.1    Mormino, E.2    Johnson, K.3
  • 19
    • 84862907684 scopus 로고    scopus 로고
    • Preclinical AD Workgroup staging: pathological correlates and potential challenges
    • [19] Jicha, G.A., Abner, E.L., Schmitt, F.A., Kryscio, R.J., Riley, K.P., Cooper, G.E., et al. Preclinical AD Workgroup staging: pathological correlates and potential challenges. Neurobiol Aging 33 (2012), 622.e1–622.e16.
    • (2012) Neurobiol Aging , vol.33 , pp. 622.e1-622.e16
    • Jicha, G.A.1    Abner, E.L.2    Schmitt, F.A.3    Kryscio, R.J.4    Riley, K.P.5    Cooper, G.E.6
  • 20
    • 84856002055 scopus 로고    scopus 로고
    • National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
    • [20] Hyman, B.T., Phelps, C.H., Beach, T.G., Bigio, E.H., Cairns, N.J., Carrillo, M.C., et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement 8 (2012), 1–13.
    • (2012) Alzheimers Dement , vol.8 , pp. 1-13
    • Hyman, B.T.1    Phelps, C.H.2    Beach, T.G.3    Bigio, E.H.4    Cairns, N.J.5    Carrillo, M.C.6
  • 21
    • 84865529158 scopus 로고    scopus 로고
    • Clinical and biomarker changes in dominantly inherited Alzheimer's disease
    • [21] Bateman, R.J., Xiong, C., Benzinger, T.L., Fagan, A.M., Goate, A., Fox, N.C., et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med 367 (2012), 795–804.
    • (2012) N Engl J Med , vol.367 , pp. 795-804
    • Bateman, R.J.1    Xiong, C.2    Benzinger, T.L.3    Fagan, A.M.4    Goate, A.5    Fox, N.C.6
  • 22
    • 0003725206 scopus 로고    scopus 로고
    • Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Part 1: Diagnosis and Classification of Diabetes Mellitus
    • Geneva. Available at:. Accessed February 16, 2017
    • [22] WHO. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Part 1: Diagnosis and Classification of Diabetes Mellitus. 1999 Geneva. Available at: http://apps.who.int/iris/bitstream/10665/66040/1/WHO_NCD_NCS_99.2.pdf. Accessed February 16, 2017.
    • (1999)
  • 23
    • 84959349986 scopus 로고    scopus 로고
    • Dementia: the rising global tide of cognitive impairment
    • [23] Hampel, H., Lista, S., Dementia: the rising global tide of cognitive impairment. Nat Rev Neurol 12 (2016), 131–132.
    • (2016) Nat Rev Neurol , vol.12 , pp. 131-132
    • Hampel, H.1    Lista, S.2
  • 24
    • 84892748542 scopus 로고    scopus 로고
    • Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease
    • [24] Doody, R.S., Thomas, R.G., Farlow, M., Iwatsubo, T., Vellas, B., Joffe, S., et al. Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease. N Engl J Med 370 (2014), 311–321.
    • (2014) N Engl J Med , vol.370 , pp. 311-321
    • Doody, R.S.1    Thomas, R.G.2    Farlow, M.3    Iwatsubo, T.4    Vellas, B.5    Joffe, S.6
  • 25
    • 84892695519 scopus 로고    scopus 로고
    • Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease
    • [25] Salloway, S., Sperling, R., Fox, N.C., Blennow, K., Klunk, W., Raskind, M., et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med 370 (2014), 322–333.
    • (2014) N Engl J Med , vol.370 , pp. 322-333
    • Salloway, S.1    Sperling, R.2    Fox, N.C.3    Blennow, K.4    Klunk, W.5    Raskind, M.6
  • 26
    • 84962309608 scopus 로고    scopus 로고
    • Toward a consensus recommendation for defining the asymptomatic-preclinical phases of putative Alzheimer's disease?
    • [26] Khachaturian, Z.S., Mesulam, M.M., Mohs, R.C., Khachaturian, A.S., Toward a consensus recommendation for defining the asymptomatic-preclinical phases of putative Alzheimer's disease?. Alzheimers Dement 12 (2016), 213–215.
    • (2016) Alzheimers Dement , vol.12 , pp. 213-215
    • Khachaturian, Z.S.1    Mesulam, M.M.2    Mohs, R.C.3    Khachaturian, A.S.4
  • 27
    • 84985896386 scopus 로고    scopus 로고
    • The antibody aducanumab reduces Aβ plaques in Alzheimer's disease
    • [27] Sevigny, J., Chiao, P., Bussière, T., Weinreb, P.H., Williams, L., Maier, M., et al. The antibody aducanumab reduces Aβ plaques in Alzheimer's disease. Nature 537 (2016), 50–56.
    • (2016) Nature , vol.537 , pp. 50-56
    • Sevigny, J.1    Chiao, P.2    Bussière, T.3    Weinreb, P.H.4    Williams, L.5    Maier, M.6
  • 28
    • 84912108664 scopus 로고    scopus 로고
    • Unrecognized preclinical Alzheimer disease confounds rs-fcMRI studies of normal aging
    • [28] Brier, M.R., Thomas, J.B., Snyder, A.Z., Wang, L., Fagan, A.M., Benzinger, T., et al. Unrecognized preclinical Alzheimer disease confounds rs-fcMRI studies of normal aging. Neurology 83 (2014), 1613–1619.
    • (2014) Neurology , vol.83 , pp. 1613-1619
    • Brier, M.R.1    Thomas, J.B.2    Snyder, A.Z.3    Wang, L.4    Fagan, A.M.5    Benzinger, T.6
  • 29
    • 84907597440 scopus 로고    scopus 로고
    • Cerebrospinal fluid beta-amyloid and phospho-tau biomarker interactions affecting brain structure in preclinical Alzheimer disease
    • [29] Fortea, J., Vilaplana, E., Alcolea, D., Carmona-Iragui, M., Sanchez-Saudinos, M.B., Sala, I., et al. Cerebrospinal fluid beta-amyloid and phospho-tau biomarker interactions affecting brain structure in preclinical Alzheimer disease. Ann Neurol 76 (2014), 223–230.
    • (2014) Ann Neurol , vol.76 , pp. 223-230
    • Fortea, J.1    Vilaplana, E.2    Alcolea, D.3    Carmona-Iragui, M.4    Sanchez-Saudinos, M.B.5    Sala, I.6
  • 30
    • 84959233450 scopus 로고    scopus 로고
    • Beta-amyloid and cognitive decline in late middle age: findings from the Wisconsin Registry for Alzheimer's Prevention study
    • [30] Clark, L.R., Racine, A.M., Koscik, R.L., Okonkwo, O.C., Engelman, C.D., Carlsson, C.M., et al. Beta-amyloid and cognitive decline in late middle age: findings from the Wisconsin Registry for Alzheimer's Prevention study. Alzheimers Dement 12 (2016), 805–814.
    • (2016) Alzheimers Dement , vol.12 , pp. 805-814
    • Clark, L.R.1    Racine, A.M.2    Koscik, R.L.3    Okonkwo, O.C.4    Engelman, C.D.5    Carlsson, C.M.6
  • 31
    • 84905969638 scopus 로고    scopus 로고
    • The preclinical Alzheimer cognitive composite: measuring amyloid-related decline
    • [31] Donohue, M.C., Sperling, R.A., Salmon, D.P., Rentz, D.M., Raman, R., Thomas, R.G., et al. The preclinical Alzheimer cognitive composite: measuring amyloid-related decline. JAMA Neurol 71 (2014), 961–970.
    • (2014) JAMA Neurol , vol.71 , pp. 961-970
    • Donohue, M.C.1    Sperling, R.A.2    Salmon, D.P.3    Rentz, D.M.4    Raman, R.5    Thomas, R.G.6
  • 32
    • 84927175617 scopus 로고    scopus 로고
    • An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease
    • [32] Langbaum, J.B., Hendrix, S.B., Ayutyanont, N., Chen, K., Fleisher, A.S., Shah, R.C., et al. An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease. Alzheimers Dement 10 (2014), 666–674.
    • (2014) Alzheimers Dement , vol.10 , pp. 666-674
    • Langbaum, J.B.1    Hendrix, S.B.2    Ayutyanont, N.3    Chen, K.4    Fleisher, A.S.5    Shah, R.C.6
  • 33
    • 84892765470 scopus 로고    scopus 로고
    • Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease
    • [33] Lim, Y.Y., Maruff, P., Pietrzak, R.H., Ames, D., Ellis, K.A., Harrington, K., et al. Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease. Brain 137 (2014), 221–231.
    • (2014) Brain , vol.137 , pp. 221-231
    • Lim, Y.Y.1    Maruff, P.2    Pietrzak, R.H.3    Ames, D.4    Ellis, K.A.5    Harrington, K.6
  • 34
    • 84970916692 scopus 로고    scopus 로고
    • Sensitivity of composite scores to amyloid burden in preclinical Alzheimer's disease: introducing the Z-scores of Attention, Verbal fluency, and Episodic memory for Nondemented older adults composite score
    • [34] Lim, Y.Y., Snyder, P.J., Pietrzak, R.H., Ukiqi, A., Villemagne, V.L., Ames, D., et al. Sensitivity of composite scores to amyloid burden in preclinical Alzheimer's disease: introducing the Z-scores of Attention, Verbal fluency, and Episodic memory for Nondemented older adults composite score. Alzheimers Dement 2 (2016), 19–26.
    • (2016) Alzheimers Dement , vol.2 , pp. 19-26
    • Lim, Y.Y.1    Snyder, P.J.2    Pietrzak, R.H.3    Ukiqi, A.4    Villemagne, V.L.5    Ames, D.6
  • 35
    • 84867528523 scopus 로고    scopus 로고
    • Indicators of amyloid burden in a population-based study of cognitively normal elderly
    • [35] Mielke, M.M., Wiste, H.J., Weigand, S.D., Knopman, D.S., Lowe, V.J., Roberts, R.O., et al. Indicators of amyloid burden in a population-based study of cognitively normal elderly. Neurology 79 (2012), 1570–1577.
    • (2012) Neurology , vol.79 , pp. 1570-1577
    • Mielke, M.M.1    Wiste, H.J.2    Weigand, S.D.3    Knopman, D.S.4    Lowe, V.J.5    Roberts, R.O.6
  • 36
    • 84923612196 scopus 로고    scopus 로고
    • Trajectories of memory decline in preclinical Alzheimer's disease: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of ageing
    • [36] Pietrzak, R.H., Lim, Y.Y., Ames, D., Harrington, K., Restrepo, C., Martins, R.N., et al. Trajectories of memory decline in preclinical Alzheimer's disease: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of ageing. Neurobiol Aging 36 (2015), 1231–1238.
    • (2015) Neurobiol Aging , vol.36 , pp. 1231-1238
    • Pietrzak, R.H.1    Lim, Y.Y.2    Ames, D.3    Harrington, K.4    Restrepo, C.5    Martins, R.N.6
  • 37
    • 79960199327 scopus 로고    scopus 로고
    • Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study
    • [37] Pike, K.E., Ellis, K.A., Villemagne, V.L., Good, N., Chetelat, G., Ames, D., et al. Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study. Neuropsychologia 49 (2011), 2384–2390.
    • (2011) Neuropsychologia , vol.49 , pp. 2384-2390
    • Pike, K.E.1    Ellis, K.A.2    Villemagne, V.L.3    Good, N.4    Chetelat, G.5    Ames, D.6
  • 38
    • 84888217049 scopus 로고    scopus 로고
    • Preclinical AD predicts decline in memory and executive functions in subjective complaints
    • [38] van Harten, A.C., Smits, L.L., Teunissen, C.E., Visser, P.J., Koene, T., Blankenstein, M.A., et al. Preclinical AD predicts decline in memory and executive functions in subjective complaints. Neurology 81 (2013), 1409–1416.
    • (2013) Neurology , vol.81 , pp. 1409-1416
    • van Harten, A.C.1    Smits, L.L.2    Teunissen, C.E.3    Visser, P.J.4    Koene, T.5    Blankenstein, M.A.6
  • 39
    • 84927176303 scopus 로고    scopus 로고
    • A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
    • [39] Jessen, F., Amariglio, R.E., van Boxtel, M., Breteler, M., Ceccaldi, M., Chetelat, G., et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimers Dement 10 (2014), 844–852.
    • (2014) Alzheimers Dement , vol.10 , pp. 844-852
    • Jessen, F.1    Amariglio, R.E.2    van Boxtel, M.3    Breteler, M.4    Ceccaldi, M.5    Chetelat, G.6
  • 40
    • 84909980100 scopus 로고    scopus 로고
    • Risk of dementia and mild cognitive impairment in older people with subjective memory complaints: meta-analysis
    • [40] Mitchell, A.J., Beaumont, H., Ferguson, D., Yadegarfar, M., Stubbs, B., Risk of dementia and mild cognitive impairment in older people with subjective memory complaints: meta-analysis. Acta Psychiatr Scand 130 (2014), 439–451.
    • (2014) Acta Psychiatr Scand , vol.130 , pp. 439-451
    • Mitchell, A.J.1    Beaumont, H.2    Ferguson, D.3    Yadegarfar, M.4    Stubbs, B.5
  • 41
    • 84938675912 scopus 로고    scopus 로고
    • Reaction Time is a Marker of Early Cognitive and Behavioral Alterations in Pure Cerebral Small Vessel Disease
    • [41] Jouvent, E., Reyes, S., De Guio, F., Chabriat, H., Reaction Time is a Marker of Early Cognitive and Behavioral Alterations in Pure Cerebral Small Vessel Disease. J Alzheimers Dis 47 (2015), 413–419.
    • (2015) J Alzheimers Dis , vol.47 , pp. 413-419
    • Jouvent, E.1    Reyes, S.2    De Guio, F.3    Chabriat, H.4
  • 42
    • 84923267269 scopus 로고    scopus 로고
    • Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
    • [42] Rohrer, J.D., Nicholas, J.M., Cash, D.M., van Swieten, J., Dopper, E., Jiskoot, L., et al. Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis. Lancet Neurol 14 (2015), 253–262.
    • (2015) Lancet Neurol , vol.14 , pp. 253-262
    • Rohrer, J.D.1    Nicholas, J.M.2    Cash, D.M.3    van Swieten, J.4    Dopper, E.5    Jiskoot, L.6
  • 43
    • 84943738470 scopus 로고    scopus 로고
    • Prediction of Alzheimer's Disease Dementia: Data from the GuidAge Prevention Trial
    • [43] Di Stefano, F., Epelbaum, S., Coley, N., Cantet, C., Ousset, P.J., Hampel, H., et al. Prediction of Alzheimer's Disease Dementia: Data from the GuidAge Prevention Trial. J Alzheimers Dis 48 (2015), 793–804.
    • (2015) J Alzheimers Dis , vol.48 , pp. 793-804
    • Di Stefano, F.1    Epelbaum, S.2    Coley, N.3    Cantet, C.4    Ousset, P.J.5    Hampel, H.6
  • 44
    • 34447322271 scopus 로고    scopus 로고
    • Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria
    • [44] Dubois, B., Feldman, H.H., Jacova, C., Dekosky, S.T., Barberger-Gateau, P., Cummings, J., et al. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 6 (2007), 734–746.
    • (2007) Lancet Neurol , vol.6 , pp. 734-746
    • Dubois, B.1    Feldman, H.H.2    Jacova, C.3    Dekosky, S.T.4    Barberger-Gateau, P.5    Cummings, J.6
  • 45
    • 77954239263 scopus 로고    scopus 로고
    • Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives
    • [45] Hampel, H., Frank, R., Broich, K., Teipel, S.J., Katz, R.G., Hardy, J., et al. Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives. Nat Rev Drug Discov 9 (2010), 560–574.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 560-574
    • Hampel, H.1    Frank, R.2    Broich, K.3    Teipel, S.J.4    Katz, R.G.5    Hardy, J.6
  • 46
    • 73549092137 scopus 로고    scopus 로고
    • Pittsburgh Compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease
    • [46] Morris, J.C., Roe, C.M., Grant, E.A., Head, D., Storandt, M., Goate, A.M., et al. Pittsburgh Compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease. Arch Neurol 66 (2009), 1469–1475.
    • (2009) Arch Neurol , vol.66 , pp. 1469-1475
    • Morris, J.C.1    Roe, C.M.2    Grant, E.A.3    Head, D.4    Storandt, M.5    Goate, A.M.6
  • 47
    • 77649314191 scopus 로고    scopus 로고
    • APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
    • [47] Morris, J.C., Roe, C.M., Xiong, C., Fagan, A.M., Goate, A.M., Holtzman, D.M., et al. APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol 67 (2010), 122–131.
    • (2010) Ann Neurol , vol.67 , pp. 122-131
    • Morris, J.C.1    Roe, C.M.2    Xiong, C.3    Fagan, A.M.4    Goate, A.M.5    Holtzman, D.M.6
  • 49
    • 84874222233 scopus 로고    scopus 로고
    • [(18)F]Flutemetamol PET imaging and cortical biopsy histopathology for fibrillar amyloid beta detection in living subjects with normal pressure hydrocephalus: pooled analysis of four studies
    • [49] Rinne, J.O., Wong, D.F., Wolk, D.A., Leinonen, V., Arnold, S.E., Buckley, C., et al. [(18)F]Flutemetamol PET imaging and cortical biopsy histopathology for fibrillar amyloid beta detection in living subjects with normal pressure hydrocephalus: pooled analysis of four studies. Acta Neuropathol 124 (2012), 833–845.
    • (2012) Acta Neuropathol , vol.124 , pp. 833-845
    • Rinne, J.O.1    Wong, D.F.2    Wolk, D.A.3    Leinonen, V.4    Arnold, S.E.5    Buckley, C.6
  • 50
    • 84942854783 scopus 로고    scopus 로고
    • Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies
    • [50] Rabin, L.A., Smart, C.M., Crane, P.K., Amariglio, R.E., Berman, L.M., Boada, M., et al. Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies. J Alzheimers Dis 48 Suppl 1 (2015), S63–S86.
    • (2015) J Alzheimers Dis , vol.48 Suppl 1 , pp. S63-S86
    • Rabin, L.A.1    Smart, C.M.2    Crane, P.K.3    Amariglio, R.E.4    Berman, L.M.5    Boada, M.6
  • 51
    • 84865477339 scopus 로고    scopus 로고
    • Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update
    • [51] del Campo, M., Mollenhauer, B., Bertolotto, A., Engelborghs, S., Hampel, H., Simonsen, A.H., et al. Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update. Biomark Med 6 (2012), 419–430.
    • (2012) Biomark Med , vol.6 , pp. 419-430
    • del Campo, M.1    Mollenhauer, B.2    Bertolotto, A.3    Engelborghs, S.4    Hampel, H.5    Simonsen, A.H.6
  • 54
    • 84951033618 scopus 로고    scopus 로고
    • Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings
    • [54] Jack, C.R. Jr., Wiste, H.J., Weigand, S.D., Knopman, D.S., Mielke, M.M., Vemuri, P., et al. Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings. Brain 138 (2015), 3747–3759.
    • (2015) Brain , vol.138 , pp. 3747-3759
    • Jack, C.R.1    Wiste, H.J.2    Weigand, S.D.3    Knopman, D.S.4    Mielke, M.M.5    Vemuri, P.6
  • 55
    • 84942197370 scopus 로고    scopus 로고
    • Donepezil decreases annual rate of hippocampal atrophy in suspected prodromal Alzheimer's disease
    • [55] Dubois, B., Chupin, M., Hampel, H., Lista, S., Cavedo, E., Croisile, B., et al. Donepezil decreases annual rate of hippocampal atrophy in suspected prodromal Alzheimer's disease. Alzheimers Dement 11 (2015), 1041–1049.
    • (2015) Alzheimers Dement , vol.11 , pp. 1041-1049
    • Dubois, B.1    Chupin, M.2    Hampel, H.3    Lista, S.4    Cavedo, E.5    Croisile, B.6
  • 56
    • 84897954102 scopus 로고    scopus 로고
    • Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020
    • [56] Hampel, H., Lista, S., Teipel, S.J., Garaci, F., Nistico, R., Blennow, K., et al. Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020. Biochem Pharmacol 88 (2014), 426–449.
    • (2014) Biochem Pharmacol , vol.88 , pp. 426-449
    • Hampel, H.1    Lista, S.2    Teipel, S.J.3    Garaci, F.4    Nistico, R.5    Blennow, K.6
  • 57
    • 84958642042 scopus 로고    scopus 로고
    • Application of systems theory in longitudinal studies on the evolution and progression of Alzheimer's disease
    • J.I. Castrillo S.G. Oliver Springer Science+Business Media New York
    • [57] Lista, S., Khachaturian, Z.S., Rujescu, D., Garaci, F., Dubois, B., Hampel, H., Application of systems theory in longitudinal studies on the evolution and progression of Alzheimer's disease. Castrillo, J.I., Oliver, S.G., (eds.) Systems Biology of Alzheimer's Disease, 2016, Springer Science+Business Media, New York, 49–67.
    • (2016) Systems Biology of Alzheimer's Disease , pp. 49-67
    • Lista, S.1    Khachaturian, Z.S.2    Rujescu, D.3    Garaci, F.4    Dubois, B.5    Hampel, H.6
  • 58
    • 85037114234 scopus 로고    scopus 로고
    • Contributions of the Framingham Heart Study to the Epidemiology of Coronary Heart Disease
    • [58] Chen, G., Levy, D., Contributions of the Framingham Heart Study to the Epidemiology of Coronary Heart Disease. JAMA Cardiol 1 (2016), 825–830.
    • (2016) JAMA Cardiol , vol.1 , pp. 825-830
    • Chen, G.1    Levy, D.2
  • 59
    • 84896114187 scopus 로고    scopus 로고
    • The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective
    • [59] Mahmood, S.S., Levy, D., Vasan, R.S., Wang, T.J., The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective. Lancet 383 (2014), 999–1008.
    • (2014) Lancet , vol.383 , pp. 999-1008
    • Mahmood, S.S.1    Levy, D.2    Vasan, R.S.3    Wang, T.J.4
  • 60
    • 77955474351 scopus 로고    scopus 로고
    • The Alzheimer's disease neuroimaging initiative: progress report and future plans
    • [60] Weiner, M.W., Aisen, P.S., Jack, C.R. Jr., Jagust, W.J., Trojanowski, J.Q., Shaw, L., et al., Alzheimer's Disease Neuroimaging Initiative. The Alzheimer's disease neuroimaging initiative: progress report and future plans. Alzheimers Dement 6 (2010), 202–211.e7.
    • (2010) Alzheimers Dement , vol.6 , pp. 202-211.e7
    • Weiner, M.W.1    Aisen, P.S.2    Jack, C.R.3    Jagust, W.J.4    Trojanowski, J.Q.5    Shaw, L.6
  • 62
    • 69549097641 scopus 로고    scopus 로고
    • The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease
    • [62] Ellis, K.A., Bush, A.I., Darby, D., De Fazio, D., Foster, J., Hudson, P., et al., AIBL Research Group. The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease. Int Psychogeriatr 21 (2009), 672–687.
    • (2009) Int Psychogeriatr , vol.21 , pp. 672-687
    • Ellis, K.A.1    Bush, A.I.2    Darby, D.3    De Fazio, D.4    Foster, J.5    Hudson, P.6
  • 63
    • 15044360058 scopus 로고    scopus 로고
    • Effects of apolipoprotein E genotype on spatial attention, working memory, and their interaction in healthy, middle-aged adults: results from the National Institute of Mental Health's BIOCARD study
    • [63] Greenwood, P.M., Lambert, C., Sunderland, T., Parasuraman, R., Effects of apolipoprotein E genotype on spatial attention, working memory, and their interaction in healthy, middle-aged adults: results from the National Institute of Mental Health's BIOCARD study. Neuropsychology 19 (2005), 199–211.
    • (2005) Neuropsychology , vol.19 , pp. 199-211
    • Greenwood, P.M.1    Lambert, C.2    Sunderland, T.3    Parasuraman, R.4
  • 64
    • 85017369681 scopus 로고    scopus 로고
    • Available at:. Accessed June 30
    • [64] The Baltimore Longitudinal Study on Aging (BLSA). Available at: https://clinicaltrials.gov/ct2/show/NCT00233272. Accessed June 30, 2016.
    • (2016)
  • 66
    • 39749166965 scopus 로고    scopus 로고
    • The Mayo Clinic Study of Aging: design and sampling, participation, baseline measures and sample characteristics
    • [66] Roberts, R.O., Geda, Y.E., Knopman, D.S., Cha, R.H., Pankratz, V.S., Boeve, B.F., et al. The Mayo Clinic Study of Aging: design and sampling, participation, baseline measures and sample characteristics. Neuroepidemiology 30 (2008), 58–69.
    • (2008) Neuroepidemiology , vol.30 , pp. 58-69
    • Roberts, R.O.1    Geda, Y.E.2    Knopman, D.S.3    Cha, R.H.4    Pankratz, V.S.5    Boeve, B.F.6
  • 68
    • 85017362401 scopus 로고    scopus 로고
    • Available at:. Accessed June 30
    • [68] National Alzheimer's Coordinating Center (NACC). Available at: https://www.alz.washington.edu/cgibin/broker93?_service=naccnew9&_program=naccwww.pubrep1.sas&TYPEF=DISPLAYIDS. Accessed June 30, 2016.
    • (2016)
  • 69
    • 0030066467 scopus 로고    scopus 로고
    • Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Findings from the Nun Study
    • [69] Snowdon, D.A., Kemper, S.J., Mortimer, J.A., Greiner, L.H., Wekstein, D.R., Markesbery, W.R., Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Findings from the Nun Study. JAMA 275 (1996), 528–532.
    • (1996) JAMA , vol.275 , pp. 528-532
    • Snowdon, D.A.1    Kemper, S.J.2    Mortimer, J.A.3    Greiner, L.H.4    Wekstein, D.R.5    Markesbery, W.R.6
  • 70
    • 84939542187 scopus 로고    scopus 로고
    • Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease
    • [70] Alcolea, D., Martínez-Lage, P., Sánchez-Juan, P., Olazarán, J., Antúnez, C., Izagirre, A., et al. Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease. Neurology 85 (2015), 626–633.
    • (2015) Neurology , vol.85 , pp. 626-633
    • Alcolea, D.1    Martínez-Lage, P.2    Sánchez-Juan, P.3    Olazarán, J.4    Antúnez, C.5    Izagirre, A.6
  • 71
    • 84884127276 scopus 로고    scopus 로고
    • Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study
    • [71] Vos, S.J., Xiong, C., Visser, P.J., Jasielec, M.S., Hassenstab, J., Grant, E.A., et al. Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study. Lancet Neurol 12 (2013), 957–965.
    • (2013) Lancet Neurol , vol.12 , pp. 957-965
    • Vos, S.J.1    Xiong, C.2    Visser, P.J.3    Jasielec, M.S.4    Hassenstab, J.5    Grant, E.A.6
  • 72
    • 28444490337 scopus 로고    scopus 로고
    • Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer's Prevention
    • [72] Sager, M.A., Hermann, B., La Rue, A., Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer's Prevention. J Geriatr Psychiatry Neurol 18 (2005), 245–249.
    • (2005) J Geriatr Psychiatry Neurol , vol.18 , pp. 245-249
    • Sager, M.A.1    Hermann, B.2    La Rue, A.3
  • 73
    • 45749110951 scopus 로고    scopus 로고
    • Effect of parental family history of Alzheimer's disease on serial position profiles
    • [73] La Rue, A., Hermann, B., Jones, J.E., Johnson, S., Asthana, S., Sager, M.A., Effect of parental family history of Alzheimer's disease on serial position profiles. Alzheimers Dement 4 (2008), 285–290.
    • (2008) Alzheimers Dement , vol.4 , pp. 285-290
    • La Rue, A.1    Hermann, B.2    Jones, J.E.3    Johnson, S.4    Asthana, S.5    Sager, M.A.6


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