BLIP-II Employs Differential Hotspot Residues To Bind Structurally Similar Staphylococcus aureus PBP2a and Class A β-Lactamases

Biochemistry

Volumn 56, Issue 8, 2017, Pages 1075-1084

  Adamski, Carolyn J ^a   Palzkill, Timothy ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ASSOCIATION REACTIONS; BACTERIA; BINDING ENERGY; PROTEINS; RATE CONSTANTS;

ALANINE-SCANNING MUTAGENESIS; BINDING AFFINITIES; INHIBITORY PROTEINS; INTERFACE RESIDUES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PENICILLIN- BINDING PROTEINS; PROTEIN-PROTEIN INTERACTIONS; STAPHYLOCOCCUS AUREUS;

BINS;

ALANINE; BACTERIAL PROTEIN; BETA LACTAMASE; BETA LACTAMASE INHIBITORY PROTEIN II; BETA LACTAMASE TEM 1; PENICILLIN BINDING PROTEIN 2A; UNCLASSIFIED DRUG; PENICILLIN BINDING PROTEIN; PROTEIN BINDING;

AROMATIZATION; ARTICLE; BACTERIAL STRAIN; BINDING AFFINITY; CELL MEMBRANE; CONTROLLED STUDY; DISSOCIATION RATE CONSTANT; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; SURFACE PLASMON RESONANCE; AMINO ACID SUBSTITUTION; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; MOLECULAR MODEL; PROTEIN DOMAIN; STAPHYLOCOCCUS AUREUS;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BETA-LACTAMASES; KINETICS; MODELS, MOLECULAR; PENICILLIN-BINDING PROTEINS; PROTEIN BINDING; PROTEIN DOMAINS; STAPHYLOCOCCUS AUREUS; SUBSTRATE SPECIFICITY;

EID: 85014237065     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.6b00978     Document Type: Article

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