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Volumn 9, Issue 8, 2017, Pages 6690-6703

Mesoporous Silica Nanoparticles as an Antitumoral-Angiogenesis Strategy

Author keywords

antiangiogenesis; cancer; invasion; mesoporous silica nanoparticles; migration; nanomedicine

Indexed keywords

CELL SIGNALING; MEDICAL NANOTECHNOLOGY; MESOPOROUS MATERIALS; NANOPARTICLES; PARTICLE SIZE; SILICA; TUMORS;

EID: 85014159926     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.6b12524     Document Type: Article
Times cited : (58)

References (75)
  • 1
    • 84957940642 scopus 로고    scopus 로고
    • World Health Organization, (accessed May 15, 2016)
    • Cancer; World Health Organization, 2016. http://www.who.int/cancer/en/ (accessed May 15, 2016).
    • (2016) Cancer
  • 2
    • 33745684527 scopus 로고    scopus 로고
    • Metastasis: A Question of Life or Death
    • Mehlen, P.; Puisieux, A. Metastasis: A Question of Life or Death Nat. Rev. Cancer 2006, 6, 449-458 10.1038/nrc1886
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 449-458
    • Mehlen, P.1    Puisieux, A.2
  • 3
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the Angiogenic Switch
    • Bergers, G.; Benjamin, L. E. Tumorigenesis and the Angiogenic Switch Nat. Rev. Cancer 2003, 3, 401-410 10.1038/nrc1093
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 4
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in Cancer and Other Diseases
    • Carmeliet, P.; Jain, R. K. Angiogenesis in Cancer and Other Diseases Nature 2000, 407, 249-257 10.1038/35025220
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 5
    • 48349107149 scopus 로고    scopus 로고
    • Tumour-Targeted Nanomedicines: Principles and Practice
    • Lammers, T.; Hennink, W. E.; Storm, G. Tumour-Targeted Nanomedicines: Principles and Practice Br. J. Cancer 2008, 99, 392-397 10.1038/sj.bjc.6604483
    • (2008) Br. J. Cancer , vol.99 , pp. 392-397
    • Lammers, T.1    Hennink, W.E.2    Storm, G.3
  • 6
    • 35248825099 scopus 로고    scopus 로고
    • Nanotechnology for Antiangiogenic Cancer Therapy
    • Kobayashi, H.; Lin, P. C. Nanotechnology for Antiangiogenic Cancer Therapy Nanomedicine 2006, 1, 17-22 10.2217/17435889.1.1.17
    • (2006) Nanomedicine , vol.1 , pp. 17-22
    • Kobayashi, H.1    Lin, P.C.2
  • 7
    • 84976385470 scopus 로고    scopus 로고
    • Therapeutic Application of Anti-Angiogenic Nanomaterials in Cancers
    • Mukherjee, S.; Patra, C. R. Therapeutic Application of Anti-Angiogenic Nanomaterials in Cancers Nanoscale 2016, 8, 12444 10.1039/C5NR07887C
    • (2016) Nanoscale , vol.8 , pp. 12444
    • Mukherjee, S.1    Patra, C.R.2
  • 8
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a Therapeutic Target
    • Ferrara, N.; Kerbel, R. S. Angiogenesis as a Therapeutic Target Nature 2005, 438, 967-974 10.1038/nature04483
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 9
    • 84904502182 scopus 로고    scopus 로고
    • Stem Cells Loaded with Nanoparticles as a Drug Carrier for in Vivo Breast Cancer Therapy
    • Cao, B.; Yang, M.; Zhu, Y.; Qu, X.; Mao, C. Stem Cells Loaded with Nanoparticles as a Drug Carrier for In Vivo Breast Cancer Therapy Adv. Mater. 2014, 26, 4627-4631 10.1002/adma.201401550
    • (2014) Adv. Mater. , vol.26 , pp. 4627-4631
    • Cao, B.1    Yang, M.2    Zhu, Y.3    Qu, X.4    Mao, C.5
  • 11
    • 84875725240 scopus 로고    scopus 로고
    • Facile Incorporation of Aggregation-Induced Emission Materials into Mesoporous Silica Nanoparticles for Intracellular Imaging and Cancer Therapy
    • Zhang, X.; Zhang, X.; Wang, S.; Liu, M.; Zhang, Y.; Tao, L.; Wei, Y. Facile Incorporation of Aggregation-Induced Emission Materials into Mesoporous Silica Nanoparticles for Intracellular Imaging and Cancer Therapy ACS Appl. Mater. Interfaces 2013, 5, 1943-1947 10.1021/am302512u
    • (2013) ACS Appl. Mater. Interfaces , vol.5 , pp. 1943-1947
    • Zhang, X.1    Zhang, X.2    Wang, S.3    Liu, M.4    Zhang, Y.5    Tao, L.6    Wei, Y.7
  • 12
    • 84994406794 scopus 로고    scopus 로고
    • Cancer Diagnosis and Imaging-Guided Photothermal Therapy Using a Dual-Modality Nanoparticle
    • Zeng, C.; Shang, W.; Liang, X.; Liang, X.; Chen, Q.; Chi, C.; Du, Y.; Fang, C.; Tian, J. Cancer Diagnosis and Imaging-Guided Photothermal Therapy Using a Dual-Modality Nanoparticle ACS Appl. Mater. Interfaces 2016, 8, 29232-29241 10.1021/acsami.6b06883
    • (2016) ACS Appl. Mater. Interfaces , vol.8 , pp. 29232-29241
    • Zeng, C.1    Shang, W.2    Liang, X.3    Liang, X.4    Chen, Q.5    Chi, C.6    Du, Y.7    Fang, C.8    Tian, J.9
  • 14
    • 84892533825 scopus 로고    scopus 로고
    • MSN Anti-Cancer Nanomedicines: Chemotherapy Enhancement, Overcoming of Drug Resistance, and Metastasis Inhibition
    • He, Q.; Shi, J. MSN Anti-Cancer Nanomedicines: Chemotherapy Enhancement, Overcoming of Drug Resistance, and Metastasis Inhibition Adv. Mater. 2014, 26, 391-411 10.1002/adma.201303123
    • (2014) Adv. Mater. , vol.26 , pp. 391-411
    • He, Q.1    Shi, J.2
  • 15
    • 55949126429 scopus 로고    scopus 로고
    • Clearance Properties of Nano-Sized Particles and Molecules as Imaging Agents: Considerations and Caveats
    • Longmire, M.; Choyke, P. L.; Kobayashi, H. Clearance Properties of Nano-Sized Particles and Molecules as Imaging Agents: Considerations and Caveats Nanomedicine 2008, 3, 703-717 10.2217/17435889.3.5.703
    • (2008) Nanomedicine , vol.3 , pp. 703-717
    • Longmire, M.1    Choyke, P.L.2    Kobayashi, H.3
  • 16
    • 84943515078 scopus 로고    scopus 로고
    • Understanding and Exploiting Nanoparticles' Intimacy with the Blood Vessel and Blood
    • Setyawati, M. I.; Tay, C. Y.; Docter, D.; Stauber, R. H.; Leong, D. T. Understanding and Exploiting Nanoparticles' Intimacy with the Blood Vessel and Blood Chem. Soc. Rev. 2015, 44, 8174-8199 10.1039/C5CS00499C
    • (2015) Chem. Soc. Rev. , vol.44 , pp. 8174-8199
    • Setyawati, M.I.1    Tay, C.Y.2    Docter, D.3    Stauber, R.H.4    Leong, D.T.5
  • 17
    • 84973169243 scopus 로고    scopus 로고
    • Tuning Endothelial Permeability with Functionalized Nanodiamonds
    • Setyawati, M. I.; Mochalin, V. N.; Leong, D. T. Tuning Endothelial Permeability with Functionalized Nanodiamonds ACS Nano 2016, 10, 1170-1181 10.1021/acsnano.5b06487
    • (2016) ACS Nano , vol.10 , pp. 1170-1181
    • Setyawati, M.I.1    Mochalin, V.N.2    Leong, D.T.3
  • 18
    • 84862807557 scopus 로고    scopus 로고
    • A Simple Approach to Prepare Monodisperse Mesoporous Silica Nanospheres with Adjustable Sizes
    • Yu, M.; Zhou, L.; Zhang, J.; Yuan, P.; Thorn, P.; Gu, W.; Yu, C. A Simple Approach to Prepare Monodisperse Mesoporous Silica Nanospheres with Adjustable Sizes J. Colloid Interface Sci. 2012, 376, 67-75 10.1016/j.jcis.2012.03.014
    • (2012) J. Colloid Interface Sci. , vol.376 , pp. 67-75
    • Yu, M.1    Zhou, L.2    Zhang, J.3    Yuan, P.4    Thorn, P.5    Gu, W.6    Yu, C.7
  • 20
    • 84881192270 scopus 로고    scopus 로고
    • Hypervalent Surface Interactions for Colloidal Stability and Doping of Silicon Nanocrystals
    • Wheeler, L. M.; Neale, N. R.; Chen, T.; Kortshagen, U. R. Hypervalent Surface Interactions for Colloidal Stability and Doping of Silicon Nanocrystals Nat. Commun. 2013, 4, 2197 10.1038/ncomms3197
    • (2013) Nat. Commun. , vol.4 , pp. 2197
    • Wheeler, L.M.1    Neale, N.R.2    Chen, T.3    Kortshagen, U.R.4
  • 21
    • 0024992388 scopus 로고
    • Evidence of an Oxidative Mechanism for the Hemolytic Activity of Silica Particles
    • Razzaboni, B. L.; Bolsaitis, P. Evidence of an Oxidative Mechanism for the Hemolytic Activity of Silica Particles Environ. Health Perspect. 1990, 87, 337-341 10.1289/ehp.9087337
    • (1990) Environ. Health Perspect. , vol.87 , pp. 337-341
    • Razzaboni, B.L.1    Bolsaitis, P.2
  • 22
    • 84966670256 scopus 로고    scopus 로고
    • Back to Basics: Exploiting the Innate Physico-Chemical Characteristics of Nanomaterials for Biomedical Applications
    • Tay, C. Y.; Setyawati, M. I.; Xie, J.; Parak, W. J.; Leong, D. T. Back to Basics: Exploiting the Innate Physico-Chemical Characteristics of Nanomaterials for Biomedical Applications Adv. Funct. Mater. 2014, 24, 5936-5955 10.1002/adfm.201401664
    • (2014) Adv. Funct. Mater. , vol.24 , pp. 5936-5955
    • Tay, C.Y.1    Setyawati, M.I.2    Xie, J.3    Parak, W.J.4    Leong, D.T.5
  • 23
    • 84900851916 scopus 로고    scopus 로고
    • Nano-Hydroxyapatite and Nano-Titanium Dioxide Exhibit Different Subcellular Distribution and Apoptotic Profile in Human Oral Epithelium
    • Tay, C. Y.; Fang, W.; Setyawati, M. I.; Chia, S. L.; Tan, K. S.; Hong, C. H.; Leong, D. T. Nano-Hydroxyapatite and Nano-Titanium Dioxide Exhibit Different Subcellular Distribution and Apoptotic Profile in Human Oral Epithelium ACS Appl. Mater. Interfaces 2014, 6, 6248-6256 10.1021/am501266a
    • (2014) ACS Appl. Mater. Interfaces , vol.6 , pp. 6248-6256
    • Tay, C.Y.1    Fang, W.2    Setyawati, M.I.3    Chia, S.L.4    Tan, K.S.5    Hong, C.H.6    Leong, D.T.7
  • 25
    • 77949439845 scopus 로고    scopus 로고
    • In vitro Angiogenesis: Endothelial Cell Tube Formation on Gelled Basement Membrane Extract
    • Arnaoutova, I.; Kleinman, H. K. In vitro Angiogenesis: Endothelial Cell Tube Formation on Gelled Basement Membrane Extract Nat. Protoc. 2010, 5, 628-635 10.1038/nprot.2010.6
    • (2010) Nat. Protoc. , vol.5 , pp. 628-635
    • Arnaoutova, I.1    Kleinman, H.K.2
  • 26
    • 14644440555 scopus 로고    scopus 로고
    • Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis
    • Hicklin, D. J.; Ellis, L. M. Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis J. Clin. Oncol. 2004, 23, 1011-1027 10.1200/JCO.2005.06.081
    • (2004) J. Clin. Oncol. , vol.23 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 27
    • 36348938884 scopus 로고    scopus 로고
    • Reactive Oxygen Species Regulate Angiogenesis and Tumor Growth through Vascular Endothelial Growth Factor
    • Xia, C.; Meng, Q.; Liu, L. Z.; Rojanasakul, Y.; Wang, X. R.; Jiang, B. H. Reactive Oxygen Species Regulate Angiogenesis and Tumor Growth through Vascular Endothelial Growth Factor Cancer Res. 2007, 67, 10823-10830 10.1158/0008-5472.CAN-07-0783
    • (2007) Cancer Res. , vol.67 , pp. 10823-10830
    • Xia, C.1    Meng, Q.2    Liu, L.Z.3    Rojanasakul, Y.4    Wang, X.R.5    Jiang, B.H.6
  • 28
    • 5544237716 scopus 로고    scopus 로고
    • Reactive Oxygen Species as Mediators of Angiogenesis Signaling: Role of NAD(P)H Oxidase
    • Ushio-Fukai, M.; Alexander, R. W. Reactive Oxygen Species as Mediators of Angiogenesis Signaling: Role of NAD(P)H Oxidase Mol. Cell. Biochem. 2004, 264, 85-97 10.1023/B:MCBI.0000044378.09409.b5
    • (2004) Mol. Cell. Biochem. , vol.264 , pp. 85-97
    • Ushio-Fukai, M.1    Alexander, R.W.2
  • 29
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, Oxidative Stress and the Biology of Ageing
    • Finkel, T.; Holbrook, N. J. Oxidants, Oxidative Stress and the Biology of Ageing Nature 2000, 408, 239-247 10.1038/35041687
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 30
    • 84884274380 scopus 로고    scopus 로고
    • Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity
    • Manke, A.; Wang, L.; Rojanasakul, Y. Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity BioMed Res. Int. 2013, 2013, 1-15 10.1155/2013/942916
    • (2013) BioMed Res. Int. , vol.2013 , pp. 1-15
    • Manke, A.1    Wang, L.2    Rojanasakul, Y.3
  • 31
    • 84903989887 scopus 로고    scopus 로고
    • Real-Time Nanoparticle-Cell Interactions in Physiological Media by Atomic Force Microscopy
    • Pyrgiotakis, G.; Blattmann, C. O.; Demokritou, P. Real-Time Nanoparticle-Cell Interactions in Physiological Media by Atomic Force Microscopy ACS Sustainable Chem. Eng. 2014, 2, 1681-1690 10.1021/sc500152g
    • (2014) ACS Sustainable Chem. Eng. , vol.2 , pp. 1681-1690
    • Pyrgiotakis, G.1    Blattmann, C.O.2    Demokritou, P.3
  • 32
    • 84894202184 scopus 로고    scopus 로고
    • Shape and Orientation Matter for the Cellular Uptake of Nonspherical Particles
    • Dasgupta, S.; Auth, T.; Gompper, G. Shape and Orientation Matter for the Cellular Uptake of Nonspherical Particles Nano Lett. 2014, 14, 687-693 10.1021/nl403949h
    • (2014) Nano Lett. , vol.14 , pp. 687-693
    • Dasgupta, S.1    Auth, T.2    Gompper, G.3
  • 33
    • 15944382742 scopus 로고    scopus 로고
    • Mitochondrial Nitric Oxide Synthase
    • Ghafourifar, P.; Cadenas, E. Mitochondrial Nitric Oxide Synthase Trends Pharmacol. Sci. 2005, 26, 190-195 10.1016/j.tips.2005.02.005
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 190-195
    • Ghafourifar, P.1    Cadenas, E.2
  • 34
    • 84885784882 scopus 로고    scopus 로고
    • In vitro Angiogenesis Induced by Tumor-Endothelial Cell Co-Culture in Bilayered, Collagen i Hydrogel Bioengineered Tumors
    • Szot, C. S.; Buchanan, C. F.; Freeman, J. W.; Rylander, M. N. In vitro Angiogenesis Induced by Tumor-Endothelial Cell Co-Culture in Bilayered, Collagen I Hydrogel Bioengineered Tumors Tissue Eng., Part C 2013, 19, 864-874 10.1089/ten.tec.2012.0684
    • (2013) Tissue Eng., Part C , vol.19 , pp. 864-874
    • Szot, C.S.1    Buchanan, C.F.2    Freeman, J.W.3    Rylander, M.N.4
  • 36
    • 11244258882 scopus 로고    scopus 로고
    • Focal Adhesion Kinase: In Command and Control of Cell Motility
    • Mitra, S. K.; Hanson, D. A.; Schlaepfer, D. D. Focal Adhesion Kinase: In Command and Control of Cell Motility Nat. Rev. Mol. Cell Biol. 2005, 6, 56-68 10.1038/nrm1549
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 56-68
    • Mitra, S.K.1    Hanson, D.A.2    Schlaepfer, D.D.3
  • 37
    • 0035516140 scopus 로고    scopus 로고
    • Transmembrane Crosstalk between the Extracellular Matrix and the Cytoskeleton
    • Geiger, B.; Bershadsky, A.; Pankov, R.; Yamada, K. M. Transmembrane Crosstalk between the Extracellular Matrix and the Cytoskeleton Nat. Rev. Mol. Cell Biol. 2001, 2, 793-805 10.1038/35099066
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 793-805
    • Geiger, B.1    Bershadsky, A.2    Pankov, R.3    Yamada, K.M.4
  • 40
    • 24344434553 scopus 로고    scopus 로고
    • Cell Adhesion Strengthening: Contributions of Adhesive Area, Integrin Binding, and Focal Adhesion Assembly
    • Gallant, N. D.; Michael, K. E.; García, A. J. Cell Adhesion Strengthening: Contributions of Adhesive Area, Integrin Binding, and Focal Adhesion Assembly Mol. Biol. Cell 2005, 16, 4329-4340 10.1091/mbc.E05-02-0170
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4329-4340
    • Gallant, N.D.1    Michael, K.E.2    García, A.J.3
  • 41
    • 36849069902 scopus 로고    scopus 로고
    • Vinculin Controls Focal Adhesion Formation by Direct Interactions with Talin and Actin
    • Humphries, J. D.; Wang, P.; Streuli, C.; Geiger, B.; Humphries, M. J.; Ballestrem, C. Vinculin Controls Focal Adhesion Formation by Direct Interactions with Talin and Actin J. Cell Biol. 2007, 179, 1043-1057 10.1083/jcb.200703036
    • (2007) J. Cell Biol. , vol.179 , pp. 1043-1057
    • Humphries, J.D.1    Wang, P.2    Streuli, C.3    Geiger, B.4    Humphries, M.J.5    Ballestrem, C.6
  • 43
    • 84888880765 scopus 로고    scopus 로고
    • Targeting Focal Adhesion Turnover in Invasive Breast Cancer Cells by the Purine Derivative Reversine
    • Bijian, K.; Lougheed, C.; Su, J.; Xu, B.; Yu, H.; Wu, J. H.; Riccio, K.; Alaoui-Jamali, M. A. Targeting Focal Adhesion Turnover in Invasive Breast Cancer Cells by the Purine Derivative Reversine Br. J. Cancer 2013, 109, 2810-2818 10.1038/bjc.2013.675
    • (2013) Br. J. Cancer , vol.109 , pp. 2810-2818
    • Bijian, K.1    Lougheed, C.2    Su, J.3    Xu, B.4    Yu, H.5    Wu, J.H.6    Riccio, K.7    Alaoui-Jamali, M.A.8
  • 44
    • 84876329949 scopus 로고    scopus 로고
    • Akt1 Promotes Focal adhesion Disassembly and Cell Motility through Phosphorylation of FAK in Growth Factor-Stimulated Cells
    • Higuchi, M.; Kihara, R.; Okazaki, T.; Aoki, I.; Suetsugu, S.; Gotoh, Y. Akt1 Promotes Focal adhesion Disassembly and Cell Motility through Phosphorylation of FAK in Growth Factor-Stimulated Cells J. Cell Sci. 2013, 126, 745-755 10.1242/jcs.112722
    • (2013) J. Cell Sci. , vol.126 , pp. 745-755
    • Higuchi, M.1    Kihara, R.2    Okazaki, T.3    Aoki, I.4    Suetsugu, S.5    Gotoh, Y.6
  • 45
    • 0028986116 scopus 로고
    • Pp125FAK-Dependent Tyrosine Phosphorylation of Paxillin Creates a High-Affinity Binding Site for Crk
    • Schaller, M. D.; Parsons, J. T. pp125FAK-Dependent Tyrosine Phosphorylation of Paxillin Creates a High-Affinity Binding Site for Crk Mol. Cell. Biol. 1995, 15, 2635-2645 10.1128/MCB.15.5.2635
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2635-2645
    • Schaller, M.D.1    Parsons, J.T.2
  • 46
    • 0036225779 scopus 로고    scopus 로고
    • Regulation of Substrate Adhesion Dynamics during Cell Motility
    • Kaverina, I.; Krylyshkina, O.; Small, J. V. Regulation of Substrate Adhesion Dynamics During Cell Motility Int. J. Biochem. Cell Biol. 2002, 34, 746-761 10.1016/S1357-2725(01)00171-6
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 746-761
    • Kaverina, I.1    Krylyshkina, O.2    Small, J.V.3
  • 49
    • 0023794840 scopus 로고
    • Selective Stabilization of Microtubules Oriented toward the Direction of Cell Migration
    • Gundersen, G. G.; Bulinski, J. C. Selective Stabilization of Microtubules Oriented toward the Direction of Cell Migration Proc. Natl. Acad. Sci. U. S. A. 1988, 85, 5946-5950 10.1073/pnas.85.16.5946
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 5946-5950
    • Gundersen, G.G.1    Bulinski, J.C.2
  • 50
    • 80052302550 scopus 로고    scopus 로고
    • Activation of Rac1-PI3K/Akt is Required for Epidermal Growth Factor-Induced PAK1 Activation and Cell Migration in MDA-MB-231 Breast Cancer Cells
    • Yang, Y.; Du, J.; Hu, Z.; Liu, J.; Tian, Y.; Zhu, Y.; Wang, L.; Gu, L. Activation of Rac1-PI3K/Akt is Required for Epidermal Growth Factor-Induced PAK1 Activation and Cell Migration in MDA-MB-231 Breast Cancer Cells J. Biomed. Res. 2011, 25, 237-245 10.1016/S1674-8301(11)60032-8
    • (2011) J. Biomed. Res. , vol.25 , pp. 237-245
    • Yang, Y.1    Du, J.2    Hu, Z.3    Liu, J.4    Tian, Y.5    Zhu, Y.6    Wang, L.7    Gu, L.8
  • 51
    • 78651260241 scopus 로고    scopus 로고
    • Lysophosphatidic Acid Induces MDA-MB-231 Breast Cancer Cells Migration through Activation of PI3K/PAK1/ERK Signaling
    • Du, J.; Sun, C.; Hu, Z.; Yang, Y.; Zhu, Y.; Zheng, D.; Gu, L.; Lu, X. Lysophosphatidic Acid Induces MDA-MB-231 Breast Cancer Cells Migration through Activation of PI3K/PAK1/ERK Signaling PLoS One 2010, 5, e15940 10.1371/journal.pone.0015940
    • (2010) PLoS One , vol.5 , pp. e15940
    • Du, J.1    Sun, C.2    Hu, Z.3    Yang, Y.4    Zhu, Y.5    Zheng, D.6    Gu, L.7    Lu, X.8
  • 52
    • 84897967408 scopus 로고    scopus 로고
    • Deferoxamine Promotes MDA-MB-231 Cell Migration and Invasion through Increased ROS-Dependent HIF-1alpha Accumulation
    • Liu, Y.; Cui, Y.; Shi, M.; Zhang, Q.; Wang, Q.; Chen, X. Deferoxamine Promotes MDA-MB-231 Cell Migration and Invasion through Increased ROS-Dependent HIF-1alpha Accumulation Cell. Physiol. Biochem. 2014, 33, 1036-1046 10.1159/000358674
    • (2014) Cell. Physiol. Biochem. , vol.33 , pp. 1036-1046
    • Liu, Y.1    Cui, Y.2    Shi, M.3    Zhang, Q.4    Wang, Q.5    Chen, X.6
  • 53
    • 0035849787 scopus 로고    scopus 로고
    • Temporal and Quantitative Regulation of Mitogen-Activated Protein Kinase (MAPK) Modulates Cell Motility and Invasion
    • Krueger, J. S.; Keshamouni, V. G.; Atanaskova, N.; Reddy, K. B. Temporal and Quantitative Regulation of Mitogen-Activated Protein Kinase (MAPK) Modulates Cell Motility and Invasion Oncogene 2001, 20, 4209-4218 10.1038/sj.onc.1204541
    • (2001) Oncogene , vol.20 , pp. 4209-4218
    • Krueger, J.S.1    Keshamouni, V.G.2    Atanaskova, N.3    Reddy, K.B.4
  • 54
    • 18344377030 scopus 로고    scopus 로고
    • The p53 Pathway: Positive and Negative Feedback Loops
    • Harris, S. L.; Levine, A. J. The p53 Pathway: Positive and Negative Feedback Loops Oncogene 2005, 24, 2899-2908 10.1038/sj.onc.1208615
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1    Levine, A.J.2
  • 55
    • 34248583886 scopus 로고    scopus 로고
    • MAP Kinase Signalling Pathways in Cancer
    • Dhillon, A. S.; Hagan, S.; Rath, O.; Kolch, W. MAP Kinase Signalling Pathways in Cancer Oncogene 2007, 26, 3279-3290 10.1038/sj.onc.1210421
    • (2007) Oncogene , vol.26 , pp. 3279-3290
    • Dhillon, A.S.1    Hagan, S.2    Rath, O.3    Kolch, W.4
  • 56
    • 4444240191 scopus 로고    scopus 로고
    • The Functional Interactions between the p53 and MAPK Signaling Pathways
    • Wu, G. S. The Functional Interactions between the p53 and MAPK Signaling Pathways Cancer Biol. Ther. 2004, 3, 156-161 10.4161/cbt.3.2.614
    • (2004) Cancer Biol. Ther. , vol.3 , pp. 156-161
    • Wu, G.S.1
  • 57
    • 78951475020 scopus 로고    scopus 로고
    • P53 and Its Mutants in Tumor Cell Migration and Invasion
    • Muller, P. A. J.; Vousden, K. H.; Norman, J. C. p53 and Its Mutants in Tumor Cell Migration and Invasion J. Cell Biol. 2011, 192, 209-218 10.1083/jcb.201009059
    • (2011) J. Cell Biol. , vol.192 , pp. 209-218
    • Muller, P.A.J.1    Vousden, K.H.2    Norman, J.C.3
  • 58
    • 33644758292 scopus 로고    scopus 로고
    • Control of Cell Migration: A Tumour Suppressor Function for p53?
    • Roger, L.; Gadea, G.; Roux, P. Control of Cell Migration: A Tumour Suppressor Function for p53? Biol. Cell 2006, 98, 141-152 10.1042/BC20050058
    • (2006) Biol. Cell , vol.98 , pp. 141-152
    • Roger, L.1    Gadea, G.2    Roux, P.3
  • 60
    • 42449114966 scopus 로고    scopus 로고
    • Transcriptional Control of Human p53-Regulated Genes
    • Riley, T.; Sontag, E.; Chen, P.; Levine, A. Transcriptional Control of Human p53-Regulated Genes Nat. Rev. Mol. Cell Biol. 2008, 9, 402-412 10.1038/nrm2395
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 402-412
    • Riley, T.1    Sontag, E.2    Chen, P.3    Levine, A.4
  • 61
    • 0033984235 scopus 로고    scopus 로고
    • The Ki-67 Protein: From the Known and the Unknown
    • Scholzen, T.; Gerdes, J. The Ki-67 Protein: From the Known and the Unknown J. Cell. Physiol. 2000, 182, 311-322 10.1002/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9
    • (2000) J. Cell. Physiol. , vol.182 , pp. 311-322
    • Scholzen, T.1    Gerdes, J.2
  • 64
    • 84898667116 scopus 로고    scopus 로고
    • Vasostatin Inhibits VEGF-Induced Endothelial Cell Proliferation, Tube Formation and Induces Cell Apoptosis under Oxygen Deprivation
    • Shu, Q.; Li, W.; Li, H.; Sun, G. Vasostatin Inhibits VEGF-Induced Endothelial Cell Proliferation, Tube Formation and Induces Cell Apoptosis under Oxygen Deprivation Int. J. Mol. Sci. 2014, 15, 6019-6030 10.3390/ijms15046019
    • (2014) Int. J. Mol. Sci. , vol.15 , pp. 6019-6030
    • Shu, Q.1    Li, W.2    Li, H.3    Sun, G.4
  • 66
    • 65849274263 scopus 로고    scopus 로고
    • Thrombospondin and Apoptosis: Molecular Mechanisms and Use for Design of Complementation Treatments
    • Mirochnik, Y.; Kwiatek, A.; Volpert, O. V. Thrombospondin and Apoptosis: Molecular Mechanisms and Use for Design of Complementation Treatments Curr. Drug Targets 2008, 9, 851-862 10.2174/138945008785909347
    • (2008) Curr. Drug Targets , vol.9 , pp. 851-862
    • Mirochnik, Y.1    Kwiatek, A.2    Volpert, O.V.3
  • 67
    • 80052667572 scopus 로고    scopus 로고
    • Pericytes Promote Endothelial Cell Survival through Induction of Autocrine VEGF-A Signaling and Bcl-w Expression
    • Franco, M.; Roswall, P.; Cortez, E.; Hanahan, D.; Pietras, K. Pericytes Promote Endothelial Cell Survival through Induction of Autocrine VEGF-A Signaling and Bcl-w Expression Blood 2011, 118, 2906-2917 10.1182/blood-2011-01-331694
    • (2011) Blood , vol.118 , pp. 2906-2917
    • Franco, M.1    Roswall, P.2    Cortez, E.3    Hanahan, D.4    Pietras, K.5
  • 68
    • 84919668228 scopus 로고    scopus 로고
    • Probing the Relevance of 3D Cancer Models in Nanomedicine Research
    • Leong, D. T.; Ng, K. W. Probing the Relevance of 3D Cancer Models in Nanomedicine Research Adv. Drug Delivery Rev. 2014, 79-80, 95-106 10.1016/j.addr.2014.06.007
    • (2014) Adv. Drug Delivery Rev. , vol.7980 , pp. 95-106
    • Leong, D.T.1    Ng, K.W.2
  • 69
    • 84922951862 scopus 로고    scopus 로고
    • Biomimicry 3D Gastrointestinal Spheroid Platform for the Assessment of Toxicity and Inflammatory Effects of Zinc Oxide Nanoparticles
    • Chia, S. L.; Tay, C. Y.; Setyawati, M. I.; Leong, D. T. Biomimicry 3D Gastrointestinal Spheroid Platform for the Assessment of Toxicity and Inflammatory Effects of Zinc Oxide Nanoparticles Small 2015, 11, 702-712 10.1002/smll.201401915
    • (2015) Small , vol.11 , pp. 702-712
    • Chia, S.L.1    Tay, C.Y.2    Setyawati, M.I.3    Leong, D.T.4
  • 70
    • 84979723176 scopus 로고    scopus 로고
    • Reality Check for Nanomaterial-Mediated Therapy with 3D Biomimetic Culture Systems
    • Tay, C. Y.; Muthu, M. S.; Chia, S. L.; Nguyen, K. T.; Feng, S.-S.; Leong, D. T. Reality Check for Nanomaterial-Mediated Therapy with 3D Biomimetic Culture Systems Adv. Funct. Mater. 2016, 26, 4046-4065 10.1002/adfm.201600476
    • (2016) Adv. Funct. Mater. , vol.26 , pp. 4046-4065
    • Tay, C.Y.1    Muthu, M.S.2    Chia, S.L.3    Nguyen, K.T.4    Feng, S.-S.5    Leong, D.T.6
  • 71
    • 84956886108 scopus 로고    scopus 로고
    • Decoupling the Direct and Indirect Biological Effects of ZnO Nanoparticles Using a Communicative Dual Cell-Type Tissue Construct
    • Chia, S. L.; Tay, C. Y.; Setyawati, M. I.; Leong, D. T. Decoupling the Direct and Indirect Biological Effects of ZnO Nanoparticles Using a Communicative Dual Cell-Type Tissue Construct Small 2016, 12, 647-657 10.1002/smll.201502306
    • (2016) Small , vol.12 , pp. 647-657
    • Chia, S.L.1    Tay, C.Y.2    Setyawati, M.I.3    Leong, D.T.4
  • 72
    • 84877150346 scopus 로고    scopus 로고
    • Silica-Based Branched Hollow Microfibers as a Biomimetic Extracellular Matrix for Promoting Tumor Cell Growth in Vitro and in Vivo
    • Qiu, P.; Qu, X.; Brackett, D. J.; Lerner, M. R.; Li, D.; Mao, C. Silica-Based Branched Hollow Microfibers as a Biomimetic Extracellular Matrix for Promoting Tumor Cell Growth In Vitro and In Vivo Adv. Mater. 2013, 25, 2492-2496 10.1002/adma.201204472
    • (2013) Adv. Mater. , vol.25 , pp. 2492-2496
    • Qiu, P.1    Qu, X.2    Brackett, D.J.3    Lerner, M.R.4    Li, D.5    Mao, C.6
  • 73
    • 80053180372 scopus 로고    scopus 로고
    • Mechanism of Anti-Angiogenic Property of Gold Nanoparticles: Role of Nanoparticle Size and Surface Charge
    • Arvizo, R. R.; Rana, S.; Miranda, O. R.; Bhattacharya, R.; Rotello, V. M.; Mukherjee, P. Mechanism of Anti-Angiogenic Property of Gold Nanoparticles: Role of Nanoparticle Size and Surface Charge Nanomedicine 2011, 7, 580-587 10.1016/j.nano.2011.01.011
    • (2011) Nanomedicine , vol.7 , pp. 580-587
    • Arvizo, R.R.1    Rana, S.2    Miranda, O.R.3    Bhattacharya, R.4    Rotello, V.M.5    Mukherjee, P.6
  • 74
  • 75
    • 84927555905 scopus 로고    scopus 로고
    • In vitro Microtumors Provide a Physiologically Predictive Tool for Breast Cancer Therapeutic Screening
    • Benton, G.; DeGray, G.; Kleinman, H. K.; George, J.; Arnaoutova, I. In vitro Microtumors Provide a Physiologically Predictive Tool for Breast Cancer Therapeutic Screening PLoS One 2015, 10, e0123312 10.1371/journal.pone.0123312
    • (2015) PLoS One , vol.10 , pp. e0123312
    • Benton, G.1    DeGray, G.2    Kleinman, H.K.3    George, J.4    Arnaoutova, I.5


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