Activation of Rac1-PI3K/Akt is required for epidermal growth factor-induced PAK1 activation and cell migration in MDA-MB-231 breast cancer cells

Journal of Biomedical Research

Volumn 25, Issue 4, 2011, Pages 237-245

  Yang, Yu ^a   Du, Jun ^a   Hu, Zhenzhen ^a   Liu, Jiaojing ^a   Tian, Yinhui ^a   Zhu, Yichao ^a   Wang, Le ^a   Gu, Luo ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer cell; Epidermal growth factor; Migration; P21 actived kinase (PAK1); PI3K Akt; Ras related c3 botulinum toxin substrate 1 (Rac1)

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLCYSTEINE; EPIDERMAL GROWTH FACTOR; P21 ACTIVATED KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL ACTIVATION; CELL MIGRATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 80052302550     PISSN: 16748301     EISSN: 16748301     Source Type: Journal    
DOI: 10.1016/S1674-8301(11)60032-8     Document Type: Article

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