Cytoprotective effect of chlorogenic acid against hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells through PI3K/Akt-mediated Nrf2/HO-1 signaling pathway

Oncotarget

Volumn 8, Issue 9, 2017, Pages 14680-14692

  Han, Dandan ^a   Chen, Wei ^a   Gu, Xiaolong ^a   Shan, Ruixue ^a   Zou, Jiaqi ^a   Liu, Gang ^a   Shahid, Muhammad ^a   Gao, Jian ^a   Han, Bo ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Chlorogenic acid; Cytoprotection; MC3T3 E1 cells; Nrf2 HO 1 pathway; Oxidative stress

Indexed keywords

CASPASE 3; CHLOROGENIC ACID; GLUTATHIONE; HEME OXYGENASE 1; MALONALDEHYDE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; HMOX1 PROTEIN, MOUSE; HYDROGEN PEROXIDE; MEMBRANE PROTEIN; NFE2L2 PROTEIN, MOUSE; OXIDIZING AGENT;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL DEATH; CELL NUCLEUS; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; IN VITRO STUDY; MOUSE; NONHUMAN; OSTEOBLAST; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; APOPTOSIS; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; METABOLISM; NUCLEOCYTOPLASMIC TRANSPORT; PHOSPHORYLATION; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL LINE; CELL SURVIVAL; CHLOROGENIC ACID; CYTOPROTECTION; HEME OXYGENASE-1; HYDROGEN PEROXIDE; MEMBRANE PROTEINS; MICE; NF-E2-RELATED FACTOR 2; OSTEOBLASTS; OXIDANTS; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 85013834257     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.14747     Document Type: Article

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