TGF-β1/Smad3 pathway targets PP2A-AMPK-FoxO1 signaling to regulate hepatic gluconeogenesis

Journal of Biological Chemistry

Volumn 292, Issue 8, 2017, Pages 3420-3432

  Yadav, Hariom ^a   Devalaraja, Samir ^a   Chung, Stephanie T ^a   Rane, Sushil G ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ACTIVITY; GLUCOSE; PHOSPHATASES; PHYSIOLOGY; PIGMENTS; PROTEINS; SIGNALING; TISSUE HOMEOSTASIS;

AMP-ACTIVATED PROTEIN KINASE; FUNCTIONAL INTERACTION; GLUCOSE-6-PHOSPHATASE; HEPATIC GLUCONEOGENESIS; NUCLEAR TRANSLOCATIONS; PHARMACOLOGICAL INHIBITION; PHOSPHOENOLPYRUVATE CARBOXYKINASE; PROTEIN PHOSPHATASE 2A;

METABOLISM;

ADENYLATE KINASE; GLUCOSE 6 PHOSPHATASE; PHOSPHOENOLPYRUVATE CARBOXYLASE; PHOSPHOPROTEIN PHOSPHATASE 2A; SMAD3 PROTEIN; TRANSCRIPTION FACTOR FKHR; TRANSFORMING GROWTH FACTOR BETA1; FOXO1 PROTEIN, MOUSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PHOSPHOPROTEIN PHOSPHATASE 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIVER GLUCONEOGENESIS; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; ANIMAL; C57BL MOUSE; FEMALE; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; METABOLISM; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DIABETES MELLITUS, TYPE 2; FEMALE; FORKHEAD BOX PROTEIN O1; GLUCONEOGENESIS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; PROTEIN PHOSPHATASE 2; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 85013801514     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.764910     Document Type: Article

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