Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma

BMC Cancer

Volumn 17, Issue 1, 2017, Pages

  Bayat Mokhtari, Reza ^a,b,d   Baluch, Narges ^c   Ka Hon Tsui, Micky ^a   Kumar, Sushil ^a   S Homayouni, Tina ^a   Aitken, Karen ^a   Das, Bikul ^d   Baruchel, Sylvain ^a   Yeger, Herman ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c QUEEN S UNIVERSITY   (Canada)

^d FORSYTH INSTITUTE   (United States)

Author keywords

Acetazolamide; Carbonic anhydrases; HDAC inhibitor; Histone deacetylases; MS 275; Neuroblastoma

Indexed keywords

ACETAZOLAMIDE; CARBONATE DEHYDRATASE; ENTINOSTAT; HISTONE DEACETYLASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; CARBONATE DEHYDRATASE INHIBITOR; HISTONE DEACETYLASE INHIBITOR; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER STEM CELL; CARCINOGENICITY; CELL CYCLE ARREST; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG POTENTIATION; DRUG TARGETING; FEMALE; MOUSE; NANOG GENE; NEUROBLASTOMA; NONHUMAN; OCT4 GENE; PHENOTYPE; PROTEIN EXPRESSION; SOX2 GENE; ANIMAL; CELL LINE; CELL MOTION; CELL PROLIFERATION; COMBINATION DRUG THERAPY; DRUG EFFECTS; DRUG SCREENING; HUMAN; TREATMENT OUTCOME;

ACETAZOLAMIDE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZAMIDES; CARBONIC ANHYDRASE INHIBITORS; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; DRUG THERAPY, COMBINATION; FEMALE; HISTONE DEACETYLASE INHIBITORS; HUMANS; MICE; NEUROBLASTOMA; PYRIDINES; TREATMENT OUTCOME; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85013788437     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-017-3126-7     Document Type: Article

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