-
2
-
-
33644655886
-
The number of people with glaucoma worldwide in 2010 and 2020
-
Quigley HA, Broman AT (2006) The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:151–156
-
(2006)
Br J Ophthalmol
, vol.90
, pp. 151-156
-
-
Quigley, H.A.1
Broman, A.T.2
-
3
-
-
2442650952
-
Clinical applications of the carbonic anhydrase inhibitors in ophthalmology
-
Supuran CT, Scozzafava A, Conway J (eds), CRC Press, Boca Rato
-
Mincione F, Menabuoni L, Supuran CT (2004) Clinical applications of the carbonic anhydrase inhibitors in ophthalmology. In: Supuran CT, Scozzafava A, Conway J (eds) Carbonic anhydrase – its inhibitors and activators. CRC Press, Boca Raton, pp 243–254
-
(2004)
Carbonic Anhydrase – Its Inhibitors and Activators
, pp. 243-254
-
-
Mincione, F.1
Menabuoni, L.2
Supuran, C.T.3
-
4
-
-
68149088937
-
Antiglaucoma carbonic anhydrase inhibitors as ophthalomologic drugs
-
In: Supuran CT, Winum JY, Wiley, Hoboke
-
Mincione F, Scozzafava A, Supuran CT (2009) Antiglaucoma carbonic anhydrase inhibitors as ophthalomologic drugs. In: Supuran CT, Winum JY (eds) Drug design of zinc-enzyme inhibitors: functional, structural, and disease applications. Wiley, Hoboken, pp 139–154
-
(2009)
Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications
, pp. 139-154
-
-
Mincione, F.1
Scozzafava, A.2
Supuran, C.T.3
-
6
-
-
0001795569
-
The formation of the intraocular fluid
-
Friedenwald JS (1949) The formation of the intraocular fluid. Am J Ophthalmol 32:9–27
-
(1949)
Am J Ophthalmol
, vol.32
, pp. 9-27
-
-
Friedenwald, J.S.1
-
7
-
-
0001147656
-
Comparative chemistry of of aqueous humor in posterior and anterior chambers of rabbit eye
-
Kinsey VE (1953) Comparative chemistry of of aqueous humor in posterior and anterior chambers of rabbit eye. Arch Ophthalmol 50:401–417
-
(1953)
Arch Ophthalmol
, vol.50
, pp. 401-417
-
-
Kinsey, V.E.1
-
8
-
-
0003180272
-
The rate flow of aqueous humor. II. Derivation of rate of flow and its physiologic significance
-
Kinsey VE, Barany E (1949) The rate flow of aqueous humor. II. Derivation of rate of flow and its physiologic significance. Am J Ophthalmol 32:189–202
-
(1949)
Am J Ophthalmol
, vol.32
, pp. 189-202
-
-
Kinsey, V.E.1
Barany, E.2
-
9
-
-
84989992371
-
Carbonic anhydrase in the anterior uvea of the rabbit
-
Wistrand PJ (1951) Carbonic anhydrase in the anterior uvea of the rabbit. Acta Physiol Scand 24:144–148
-
(1951)
Acta Physiol Scand
, vol.24
, pp. 144-148
-
-
Wistrand, P.J.1
-
10
-
-
49749205045
-
The mechanism of the fall in intraocular pressure by the carbonic anhydrase inhibitor Diamox
-
Becker B (1955) The mechanism of the fall in intraocular pressure by the carbonic anhydrase inhibitor Diamox. Am J Ophthalmol 39:177–183
-
(1955)
Am J Ophthalmol
, vol.39
, pp. 177-183
-
-
Becker, B.1
-
11
-
-
0010429778
-
Turnover of total carbon dioxide in aqueous humors and the effect thereon of acetazolamide
-
Kinsey VE, Reddy DVN (1959) Turnover of total carbon dioxide in aqueous humors and the effect thereon of acetazolamide. Arch Ophthalmol 62:78–83
-
(1959)
Arch Ophthalmol
, vol.62
, pp. 78-83
-
-
Kinsey, V.E.1
Reddy, D.2
-
12
-
-
0034018870
-
Carbonic anhydrase inhibitors and their therapeutic potential
-
Supuran CT, Scozzafava A (2000) Carbonic anhydrase inhibitors and their therapeutic potential. Expert Opin Ther Pat 10:575–600
-
(2000)
Expert Opin Ther Pat
, vol.10
, pp. 575-600
-
-
Supuran, C.T.1
Scozzafava, A.2
-
13
-
-
38849143765
-
Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators
-
Supuran CT (2008) Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nature Rev Drug Discov 7:168–181
-
(2008)
Nature Rev Drug Discov
, vol.7
, pp. 168-181
-
-
Supuran, C.T.1
-
14
-
-
77954218410
-
Carbonic anhydrase inhibitors
-
Supuran CT (2010) Carbonic anhydrase inhibitors. Bioorg Med Chem Lett 20:3467–3474
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 3467-3474
-
-
Supuran, C.T.1
-
15
-
-
78649857406
-
Carbonic anhydrase inhibition/activation: Trip of a scientist around the world in the search of novel chemotypes and drug targets
-
Supuran CT (2010) Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets. Curr Pharm Des 16:3233–3245
-
(2010)
Curr Pharm Des
, vol.16
, pp. 3233-3245
-
-
Supuran, C.T.1
-
17
-
-
0014135426
-
Carbonic anhydrase: Chemistry, physiology and inhibition
-
Maren TH (1967) Carbonic anhydrase: chemistry, physiology and inhibition. Physiol Rev 47:595–781
-
(1967)
Physiol Rev
, vol.47
, pp. 595-781
-
-
Maren, T.H.1
-
18
-
-
0000974035
-
Heterocyclic sulfonamides as carbonic anhydrase inhibitors
-
Miller WH, Dessert AM, Roblin RO Jr (1950) Heterocyclic sulfonamides as carbonic anhydrase inhibitors. J Am Chem Soc 72:4893–4896
-
(1950)
J am Chem Soc
, vol.72
, pp. 4893-4896
-
-
Miller, W.H.1
Dessert, A.M.2
Roblin, R.O.3
-
19
-
-
5144224910
-
Development of sulfonamide carbonic anhydrase inhibitors (CAIs)
-
Supuran CT, Scozzafava A, Conway J (eds), CRC Press, Boca Rato
-
Supuran CT, Scozzafava A, Casini A (2004) Development of sulfonamide carbonic anhydrase inhibitors (CAIs). In: Supuran CT, Scozzafava A, Conway J (eds) Carbonic anhydrase – its inhibitors and activators. CRC Press, Boca Raton, pp 67–147
-
(2004)
Carbonic Anhydrase – Its Inhibitors and Activators
, pp. 67-147
-
-
Supuran, C.T.1
Scozzafava, A.2
Casini, A.3
-
20
-
-
0037374846
-
Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: Overexpression of CA12 (CAXII) in glaucoma
-
Liao SY, Ivanov S, Ivanova A, Ghosh S, Cote MA, Keefe K, Coca-Prados M, Stanbridge EJ, Lerman MI (2003) Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma. J Med Genet 40:257–261
-
(2003)
J Med Genet
, vol.40
, pp. 257-261
-
-
Liao, S.Y.1
Ivanov, S.2
Ivanova, A.3
Ghosh, S.4
Cote, M.A.5
Keefe, K.6
Coca-Prados, M.7
Stanbridge, E.J.8
Lerman, M.I.9
-
21
-
-
0020630921
-
The transcorneal permeability of sulfonamide carbonic anhydrase innhibitors and their effect on aqueous humor secretion
-
Maren TH, Jankowska L, Sanyal G, Edelhauser HF (1983) The transcorneal permeability of sulfonamide carbonic anhydrase innhibitors and their effect on aqueous humor secretion. Exp Eye Res 36:457–480
-
(1983)
Exp Eye Res
, vol.36
, pp. 457-480
-
-
Maren, T.H.1
Jankowska, L.2
Sanyal, G.3
Edelhauser, H.F.4
-
22
-
-
0033990833
-
Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors
-
Sugrue MF (2000) Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors. Prog Ret Eye Res 19:87–112
-
(2000)
Prog Ret Eye Res
, vol.19
, pp. 87-112
-
-
Sugrue, M.F.1
-
23
-
-
0031023338
-
Comparison of dorzolamide and acetazolamide as suppresors of aqueous humor flow in humans
-
Maus TL, Larsson LI, McLaren JW, Brubaker RF (1997) Comparison of dorzolamide and acetazolamide as suppresors of aqueous humor flow in humans. Arch Ophthalmol 115:45–49
-
(1997)
Arch Ophthalmol
, vol.115
, pp. 45-49
-
-
Maus, T.L.1
Larsson, L.I.2
McLaren, J.W.3
Brubaker, R.F.4
-
24
-
-
0034014371
-
Dose–response evaluation of the ocular hypotensive effect of brinzolamide ophthalmic suspension (Azopt). Brinzolamide dose–response study group
-
Silver LH (2000) Dose–response evaluation of the ocular hypotensive effect of brinzolamide ophthalmic suspension (Azopt). Brinzolamide dose–response study group. Surv Ophthalmol 44(suppl 2):147–153
-
(2000)
Surv Ophthalmol
, vol.44
, pp. 147-153
-
-
Silver, L.H.1
-
25
-
-
14444286947
-
Contact allergy to dorzolamide eyedrops
-
Aalto-Korte K (1998) Contact allergy to dorzolamide eyedrops. Contact Dermatitis 39:206
-
(1998)
Contact Dermatitis
, vol.39
, pp. 206
-
-
Aalto-Korte, K.1
-
27
-
-
0032693051
-
Anorexia, depression and dementia induced by dorzolamide eyedrops (Trusopt)
-
Thoe Schwartzenberg GW, Trop GE (1999) Anorexia, depression and dementia induced by dorzolamide eyedrops (Trusopt). Can J Ophthalmol 34:93–94
-
(1999)
Can J Ophthalmol
, vol.34
, pp. 93-94
-
-
Thoe Schwartzenberg, G.W.1
Trop, G.E.2
-
28
-
-
0033119461
-
Irreversible corneal decompensation in patients treated with topical dorzolamide
-
Konowal A, Morrison JC, Brown SV, Cooke DL, Maguire LJ, Verdier DV (1999) Irreversible corneal decompensation in patients treated with topical dorzolamide. Am J Ophthalmol 127:403–406
-
(1999)
Am J Ophthalmol
, vol.127
, pp. 403-406
-
-
Konowal, A.1
Morrison, J.C.2
Brown, S.V.3
Cooke, D.L.4
Maguire, L.J.5
Verdier, D.V.6
-
29
-
-
0033566151
-
Carbonic anhydrase inhibitors: Synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: Is the tail more important than the ring?
-
Scozzafava A, Menabuoni L, Mincione F, Briganti F, Mincione G, Supuran CT (1999) Carbonic anhydrase inhibitors: synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? J Med Chem 42:2641–2650
-
(1999)
J Med Chem
, vol.42
, pp. 2641-2650
-
-
Scozzafava, A.1
Menabuoni, L.2
Mincione, F.3
Briganti, F.4
Mincione, G.5
Supuran, C.T.6
-
30
-
-
0033539043
-
Carbonic anhydrase inhibitors. Synthesis of water-soluble, amino acyl/dipeptidyl sulfonamides possessing long lasting-intraocular pressure lowering properties via the topical route
-
Scozzafava A, Briganti F, Mincione G, Menabuoni L, Mincione F, Supuran CT (1999) Carbonic anhydrase inhibitors. Synthesis of water-soluble, amino acyl/dipeptidyl sulfonamides possessing long lasting-intraocular pressure lowering properties via the topical route. J Med Chem 42:3690–3700
-
(1999)
J Med Chem
, vol.42
, pp. 3690-3700
-
-
Scozzafava, A.1
Briganti, F.2
Mincione, G.3
Menabuoni, L.4
Mincione, F.5
Supuran, C.T.6
-
31
-
-
0034676310
-
Carbonic anhydrase inhibitors: Perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure lowering agents with prolonged duration of action
-
Scozzafava A, Menabuoni L, Mincione F, Briganti F, Mincione G, Supuran CT (2000) Carbonic anhydrase inhibitors: perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure lowering agents with prolonged duration of action. J Med Chem 43:4542–4551
-
(2000)
J Med Chem
, vol.43
, pp. 4542-4551
-
-
Scozzafava, A.1
Menabuoni, L.2
Mincione, F.3
Briganti, F.4
Mincione, G.5
Supuran, C.T.6
-
32
-
-
0037187391
-
Carbonic anhydrase inhibitors. A general approach for the preparation of water soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long lasting, topical intraocular pressure lowering properties
-
Scozzafava A, Menabuoni L, Mincione F, Supuran CT (2002) Carbonic anhydrase inhibitors. A general approach for the preparation of water soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long lasting, topical intraocular pressure lowering properties. J Med Chem 45:1466–1476
-
(2002)
J Med Chem
, vol.45
, pp. 1466-1476
-
-
Scozzafava, A.1
Menabuoni, L.2
Mincione, F.3
Supuran, C.T.4
-
33
-
-
84863501358
-
Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms?
-
Alterio V, Di Fiore A, D’Ambrosio K, Supuran CT, De Simone G (2012) Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms? Chem Rev 112:4421–4468
-
(2012)
Chem Rev
, vol.112
, pp. 4421-4468
-
-
Alterio, V.1
Di Fiore, A.2
D’Ambrosio, K.3
Supuran, C.T.4
De Simone, G.5
-
34
-
-
79961070760
-
Carbonic anhydrase inhibitors and activators for novel therapeutic applications
-
Supuran CT (2011) Carbonic anhydrase inhibitors and activators for novel therapeutic applications. Future Med Chem 3:1165–1180
-
(2011)
Future Med Chem
, vol.3
, pp. 1165-1180
-
-
Supuran, C.T.1
-
35
-
-
84865850354
-
Structure-based drug discovery of carbonic anhydrase inhibitors
-
Supuran CT (2012) Structure-based drug discovery of carbonic anhydrase inhibitors. J Enzyme Inhib Med Chem 27:759–772
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 759-772
-
-
Supuran, C.T.1
-
36
-
-
71749104748
-
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma
-
Steele RM, Batugo MR, Benedini F, Biondi S, Borghi V, Carzaniga L, Impagnatiello F, Miglietta D, Chong WK, Rajapakse R, Cecchi A, Temperini C, Supuran CT (2009) Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma. Bioorg Med Chem Lett 19:6565–6570
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 6565-6570
-
-
Steele, R.M.1
Batugo, M.R.2
Benedini, F.3
Biondi, S.4
Borghi, V.5
Carzaniga, L.6
Impagnatiello, F.7
Miglietta, D.8
Chong, W.K.9
Rajapakse, R.10
Cecchi, A.11
Temperini, C.12
Supuran, C.T.13
-
37
-
-
79956062824
-
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action
-
Mincione F, Benedini F, Biondi S, Cecchi A, Temperini C, Formicola G, Pacileo I, Scozzafava A, Masini E, Supuran CT (2011) Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action. Bioorg Med Chem Lett 21:3216–3221
-
(2011)
Bioorg Med Chem Lett
, vol.21
, pp. 3216-3221
-
-
Mincione, F.1
Benedini, F.2
Biondi, S.3
Cecchi, A.4
Temperini, C.5
Formicola, G.6
Pacileo, I.7
Scozzafava, A.8
Masini, E.9
Supuran, C.T.10
-
38
-
-
84855408335
-
A new approach to antiglaucoma drugs: Carbonic anhydrase inhibitors with or without NO donating moieties.Mechanism of action and preliminary pharmacology
-
Fabrizi F, Mincione F, Somma T, Scozzafava G, Galassi F, Masini E, Impagnatiello F, Supuran CT (2012) A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties.Mechanism of action and preliminary pharmacology. J Enzyme Inhib Med Chem 27:138–147
-
(2012)
J Enzyme Inhib Med Chem
, vol.27
, pp. 138-147
-
-
Fabrizi, F.1
Mincione, F.2
Somma, T.3
Scozzafava, G.4
Galassi, F.5
Masini, E.6
Impagnatiello, F.7
Supuran, C.T.8
-
39
-
-
84872915972
-
A Multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma
-
Long DD, Frieman B, Hegde SS, Hill CM, Jiang L, Kintz S, Marquess DG, Purkey H, Shaw JP, Steinfeld T, Wilson MS, Wrench K (2013) A Multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma. Bioorg Med Chem Lett 23:939–943
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 939-943
-
-
Long, D.D.1
Frieman, B.2
Hegde, S.S.3
Hill, C.M.4
Jiang, L.5
Kintz, S.6
Marquess, D.G.7
Purkey, H.8
Shaw, J.P.9
Steinfeld, T.10
Wilson, M.S.11
Wrench, K.12
-
40
-
-
84855702121
-
Dithiocarbamates: A new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations
-
Carta F, Aggarwal M, Maresca A, Scozzafava A, McKenna R, Supuran CT (2012) Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. Chem Commun (Cambridge) 48:1868–1870
-
(2012)
Chem Commun (Cambridge)
, vol.48
, pp. 1868-1870
-
-
Carta, F.1
Aggarwal, M.2
Maresca, A.3
Scozzafava, A.4
McKenna, R.5
Supuran, C.T.6
-
41
-
-
84857420193
-
Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo
-
Carta F, Aggarwal M, Maresca A, Scozzafava A, McKenna R, Masini E, Supuran CT (2012) Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo. J Med Chem 55:1721–1730
-
(2012)
J Med Chem
, vol.55
, pp. 1721-1730
-
-
Carta, F.1
Aggarwal, M.2
Maresca, A.3
Scozzafava, A.4
McKenna, R.5
Masini, E.6
Supuran, C.T.7
-
42
-
-
84855658697
-
Dithiocarbamates strongly inhibit the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata
-
Monti SM, Maresca A, Viparelli F, Carta F, De Simone G, Mühlschlegel FA, Scozzafava A, Supuran CT (2012) Dithiocarbamates strongly inhibit the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata. Bioorg Med Chem Lett 22:859–862
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 859-862
-
-
Monti, S.M.1
Maresca, A.2
Viparelli, F.3
Carta, F.4
De Simone, G.5
Mühlschlegel, F.A.6
Scozzafava, A.7
Supuran, C.T.8
-
43
-
-
84874604544
-
Dithiocarbamates strongly inhibit the betaclass carbonic anhydrases from Mycobacterium tuberculosis
-
Maresca A, Carta F, Vullo D, Supuran CT (2013) Dithiocarbamates strongly inhibit the betaclass carbonic anhydrases from Mycobacterium tuberculosis. J Enzyme Inhib Med Chem 28:407–411
-
(2013)
J Enzyme Inhib Med Chem
, vol.28
, pp. 407-411
-
-
Maresca, A.1
Carta, F.2
Vullo, D.3
Supuran, C.T.4
-
44
-
-
72249106865
-
Carbonic anhydrase inhibitors. X-Ray crystal studies of the carbonic anhydrase II – trithiocarbonate adduct – an inhibitor mimicking the sulfonamide and urea binding to the enzyme
-
Temperini C, Scozzafava A, Supuran CT (2010) Carbonic anhydrase inhibitors. X-Ray crystal studies of the carbonic anhydrase II – trithiocarbonate adduct – an inhibitor mimicking the sulfonamide and urea binding to the enzyme. Bioorg Med Chem Lett 20:474–478
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 474-478
-
-
Temperini, C.1
Scozzafava, A.2
Supuran, C.T.3
|