Enhancing NAD+ salvage metabolism is neuroprotective in a PINK1 model of Parkinson's disease

Biology Open

Volumn 6, Issue 2, 2017, Pages 141-147

  Lehmann, Susann ^a   Loh, Samantha H Y ^a   Martins, L Miguel ^a  

^a MRC TOXICOLOGY UNIT   (United Kingdom)

Author keywords

Drosophila; Mitochondria; NAD+; NAM; Niacin; Nucleotide metabolism; Parkinson's disease; Parp; Pink1

Indexed keywords

NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE RIBONUCLEOTIDE; NICOTINAMIDE RIBOSIDE; RIBONUCLEOTIDE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOPAMINERGIC NERVE CELL; GENE MUTATION; MITOCHONDRIAL TOXICITY; MITOCHONDRION; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE METABOLISM; OXIDATIVE STRESS; PARKINSON DISEASE; PINK1 MUTANT (DROSOPHILA);

EID: 85013657114     PISSN: None     EISSN: 20466390     Source Type: Journal    
DOI: 10.1242/bio.022186     Document Type: Article

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