-
1
-
-
0034646514
-
New animal models for parkinson's disease
-
Dawson TM. New animal models for Parkinson's disease. Cell 2000; 101: 115-118
-
(2000)
Cell
, vol.101
, pp. 115-118
-
-
Dawson, T.M.1
-
2
-
-
0035297146
-
Caspase-3 activation in 1-methyl-4-phenyl-1 2 36-Tetrahydropyridine (MPTP)-Treated mice
-
Turmel H, Hartmann A, Parain K, Douhou A, Srinivasan A, Agid Y, et al. Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated mice. Mov Disord 2001; 16: 185-189
-
(2001)
Mov Disord
, vol.16
, pp. 185-189
-
-
Turmel, H.1
Hartmann, A.2
Parain, K.3
Douhou, A.4
Srinivasan, A.5
Agid, Y.6
-
3
-
-
0347363811
-
6-Hydroxydopamine increases the level of TNFalpha and bax mRNA in the striatum and induces apoptosis of dopaminergic neurons in hemiparkinsonian rats
-
Mladenovic A, Perovic M, Raicevic N, Kanazir S, Rakic L, Ruzdijic S. 6-Hydroxydopamine increases the level of TNFalpha and bax mRNA in the striatum and induces apoptosis of dopaminergic neurons in hemiparkinsonian rats. Brain Res 2004; 996: 237-245
-
(2004)
Brain Res
, vol.996
, pp. 237-245
-
-
Mladenovic, A.1
Perovic, M.2
Raicevic, N.3
Kanazir, S.4
Rakic, L.5
Ruzdijic, S.6
-
4
-
-
65549091910
-
Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases
-
Yang L, Calingasan NY, Wille EJ, Cormier K, Smith K, Ferrante RJ, et al. Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases. J Neurochem 2009; 109: 1427-1439
-
(2009)
J Neurochem
, vol.109
, pp. 1427-1439
-
-
Yang, L.1
Calingasan, N.Y.2
Wille, E.J.3
Cormier, K.4
Smith, K.5
Ferrante, R.J.6
-
5
-
-
77957994659
-
Multiple defects in energy metabolism in Alzheimer's disease
-
Ferreira IL, Resende R, Ferreiro E, Rego AC, Pereira CF. Multiple defects in energy metabolism in Alzheimer's disease. Curr Drug Targets 2010; 11: 1193-1206
-
(2010)
Curr Drug Targets
, vol.11
, pp. 1193-1206
-
-
Ferreira, I.L.1
Resende, R.2
Ferreiro, E.3
Rego, A.C.4
Pereira, C.F.5
-
6
-
-
0031684326
-
Mitochondria in the etiology and pathogenesis of Parkinson's disease
-
Schapira AH, Gu M, Taanman JW, Tabrizi SJ, Seaton T, Cleeter M, et al. Mitochondria in the etiology and pathogenesis of Parkinson's disease. Ann Neurol 1998; 44: S89-S98
-
(1998)
Ann Neurol
, vol.44
-
-
Schapira, A.H.1
Gu, M.2
Taanman, J.W.3
Tabrizi, S.J.4
Seaton, T.5
Cleeter, M.6
-
7
-
-
33744977254
-
The pathogenesis of cell death in Parkinson's disease
-
Jenner P, Olanow CW. The pathogenesis of cell death in Parkinson's disease. Neurology 2006; 66: S24-S36
-
(2006)
Neurology
, vol.66
-
-
Jenner, P.1
Olanow, C.W.2
-
8
-
-
0025372762
-
The mptp model: Versatile contributions to the treatment of idiopathic parkinson's disease
-
Bloem BR, Irwin I, Buruma OJ, Haan J, Roos RA, Tetrud JW, et al. The MPTP model: Versatile contributions to the treatment of idiopathic Parkinson's disease. J Neurol Sci 1990; 97: 273-293
-
(1990)
J Neurol Sci
, vol.97
, pp. 273-293
-
-
Bloem, B.R.1
Irwin, I.2
Buruma, O.J.3
Haan, J.4
Roos, R.A.5
Tetrud, J.W.6
-
9
-
-
0025942723
-
Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease
-
Hattori N, Tanaka M, Ozawa T, Mizuno Y. Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease. Ann Neurol 1991; 30: 563-571
-
(1991)
Ann Neurol
, vol.30
, pp. 563-571
-
-
Hattori, N.1
Tanaka, M.2
Ozawa, T.3
Mizuno, Y.4
-
10
-
-
79959305691
-
Mitochondria: The next (neurode)generation
-
Schon EA, Przedborski S. Mitochondria: The next (neurode)generation. Neuron 2011; 70: 1033-1053
-
(2011)
Neuron
, vol.70
, pp. 1033-1053
-
-
Schon, E.A.1
Przedborski, S.2
-
11
-
-
0033545925
-
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1 2 3 6-Tetrahydropyridine (MPTP)-induced parkinsonism
-
Mandir AS, Przedborski S, Jackson-Lewis V, Wang ZQ, Simbulan-Rosenthal CM, Smulson ME, et al. Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3, 6-Tetrahydropyridine (MPTP)-induced parkinsonism. Proc Natl Acad Sci USA 1999; 96: 5774-5779
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5774-5779
-
-
Mandir, A.S.1
Przedborski, S.2
Jackson-Lewis, V.3
Wang, Z.Q.4
Simbulan-Rosenthal, C.M.5
Smulson, M.E.6
-
12
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virag L, Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 2002; 54: 375-429
-
(2002)
Pharmacol Rev
, vol.54
, pp. 375-429
-
-
Virag, L.1
Szabo, C.2
-
13
-
-
0032193692
-
Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death
-
Virag L, Salzman AL, Szabo C. Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death. J Immunol 1998; 161: 3753-3759
-
(1998)
J Immunol
, vol.161
, pp. 3753-3759
-
-
Virag, L.1
Salzman, A.L.2
Szabo, C.3
-
14
-
-
0036196425
-
Activation and caspase-mediated inhibition of PARP: A molecular switch between fibroblast necrosis and apoptosis in death receptor signaling
-
Los M, Mozoluk M, Ferrari D, Stepczynska A, Stroh C, Renz A, et al. Activation and caspase-mediated inhibition of PARP: A molecular switch between fibroblast necrosis and apoptosis in death receptor signaling. Mol Biol Cell 2002; 13: 978-988
-
(2002)
Mol Biol Cell
, vol.13
, pp. 978-988
-
-
Los, M.1
Mozoluk, M.2
Ferrari, D.3
Stepczynska, A.4
Stroh, C.5
Renz, A.6
-
15
-
-
33845317242
-
Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death
-
Yu SW, Andrabi SA, Wang H, Kim NS, Poirier GG, Dawson TM, et al. Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc Natl Acad Sci USA 2006; 103: 18314-18319
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18314-18319
-
-
Yu, S.W.1
Andrabi, S.A.2
Wang, H.3
Kim, N.S.4
Poirier, G.G.5
Dawson, T.M.6
-
16
-
-
27444446861
-
Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stress
-
Tapodi A, Debreceni B, Hanto K, Bognar Z, Wittmann I, Gallyas F Jr., et al. Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stress. J Biol Chem 2005; 280: 35767-35775
-
(2005)
J Biol Chem
, vol.280
, pp. 35767-35775
-
-
Tapodi, A.1
Debreceni, B.2
Hanto, K.3
Bognar, Z.4
Wittmann, I.5
Gallyas Jr., F.6
-
17
-
-
79953840957
-
Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos
-
Wang Y, Kim NS, Haince JF, Kang HC, David KK, Andrabi SA, et al. Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). Sci Signal 2011; 4: Ra20
-
(2011)
Sci Signal
, vol.4
-
-
Wang, Y.1
Kim, N.S.2
Haince, J.F.3
Kang, H.C.4
David, K.K.5
Andrabi, S.A.6
-
18
-
-
80054733292
-
Dissociation of progressive dopaminergic neuronal death and behavioral impairments by bax deletion in a mouse model of Parkinson's diseases
-
Kim TW, Moon Y, Kim K, Lee JE, Koh HC, Rhyu IJ, et al. Dissociation of progressive dopaminergic neuronal death and behavioral impairments by bax deletion in a mouse model of Parkinson's diseases. PLoS ONE 2011; 6: E25346
-
(2011)
PLoS ONE
, vol.6
-
-
Kim, T.W.1
Moon, Y.2
Kim, K.3
Lee, J.E.4
Koh, H.C.5
Rhyu, I.J.6
-
19
-
-
0038043242
-
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD depletion and cell death induced by oxidative stress
-
Du L, Zhang X, Han YY, Burke NA, Kochanek PM, Watkins SC, et al. Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD depletion and cell death induced by oxidative stress. J Biol Chem 2003; 278: 18426-18433
-
(2003)
J Biol Chem
, vol.278
, pp. 18426-18433
-
-
Du, L.1
Zhang, X.2
Han, Y.Y.3
Burke, N.A.4
Kochanek, P.M.5
Watkins, S.C.6
-
20
-
-
0033815967
-
Characterization of the role of AMP-Activated protein kinase in the regulation of glucoseactivated gene expression using constitutively active and dominant negative forms of the kinase
-
Woods A, Azzout-Marniche D, Foretz M, Stein SC, Lemarchand P, Ferre P, et al. Characterization of the role of AMP-Activated protein kinase in the regulation of glucoseactivated gene expression using constitutively active and dominant negative forms of the kinase. Mol Cell Biol 2000; 20: 6704-6711
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6704-6711
-
-
Woods, A.1
Azzout-Marniche, D.2
Foretz, M.3
Stein, S.C.4
Lemarchand, P.5
Ferre, P.6
-
22
-
-
34548095002
-
Metformin therapy in a transgenic mouse model of huntington's disease
-
Ma TC, Buescher JL, Oatis B, Funk JA, Nash AJ, Carrier RL, et al. Metformin therapy in a transgenic mouse model of Huntington's disease. Neurosci Lett 2007; 411: 98-103
-
(2007)
Neurosci Lett
, vol.411
, pp. 98-103
-
-
Ma, T.C.1
Buescher, J.L.2
Oatis, B.3
Funk, J.A.4
Nash, A.J.5
Carrier, R.L.6
-
23
-
-
62649115914
-
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
-
Chen Y, Zhou K, Wang R, Liu Y, Kwak YD, Ma T, et al. Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription. Proc Natl Acad Sci USA 2009; 106: 3907-3912
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3907-3912
-
-
Chen, Y.1
Zhou, K.2
Wang, R.3
Liu, Y.4
Kwak, Y.D.5
Ma, T.6
-
24
-
-
42949088694
-
Inhibition of AMP-Activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53
-
Kim HS, Hwang JT, Yun H, Chi SG, Lee SJ, Kang I, et al. Inhibition of AMP-Activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53. J Biol Chem 2008; 283: 3731-3742
-
(2008)
J Biol Chem
, vol.283
, pp. 3731-3742
-
-
Kim, H.S.1
Hwang, J.T.2
Yun, H.3
Chi, S.G.4
Lee, S.J.5
Kang, I.6
-
25
-
-
0033003004
-
Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis
-
Herceg Z, Wang ZQ. Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis. Mol Cell Biol 1999; 19: 5124-5133
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5124-5133
-
-
Herceg, Z.1
Wang, Z.Q.2
-
26
-
-
34347344991
-
Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis
-
Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J, et al. Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol Cell Biol 2007; 27: 4844-4862
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4844-4862
-
-
Moubarak, R.S.1
Yuste, V.J.2
Artus, C.3
Bouharrour, A.4
Greer, P.A.5
Menissier-De Murcia, J.6
-
27
-
-
0037713529
-
Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease
-
Wang H, Shimoji M, Yu SW, Dawson TM, Dawson VL. Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease. Ann N Y Acad Sci 2003; 991: 132-139
-
(2003)
Ann N Y Acad Sci
, vol.991
, pp. 132-139
-
-
Wang, H.1
Shimoji, M.2
Yu, S.W.3
Dawson, T.M.4
Dawson, V.L.5
-
28
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, et al. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 2002; 297: 259-263
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
-
29
-
-
33646827842
-
Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation
-
Xu Y, Huang S, Liu ZG, Han J. Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J Biol Chem 2006; 281: 8788-8795
-
(2006)
J Biol Chem
, vol.281
, pp. 8788-8795
-
-
Xu, Y.1
Huang, S.2
Liu, Z.G.3
Han, J.4
-
30
-
-
0033396991
-
Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases
-
Mattson MP, Pedersen WA, Duan W, Culmsee C, Camandola S. Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. Ann N Y Acad Sci 1999; 893: 154-175
-
(1999)
Ann N Y Acad Sci
, vol.893
, pp. 154-175
-
-
Mattson, M.P.1
Pedersen, W.A.2
Duan, W.3
Culmsee, C.4
Camandola, S.5
-
32
-
-
79952939192
-
Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure
-
Sugiura Y, Taguchi R, Setou M. Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure. PLoS One 2011; 6: E17952
-
(2011)
PLoS One
, vol.6
-
-
Sugiura, Y.1
Taguchi, R.2
Setou, M.3
-
33
-
-
0344081177
-
Minireview: The AMP-Activated protein kinase cascade: The key sensor of cellular energy status
-
Hardie DG. Minireview: The AMP-Activated protein kinase cascade: The key sensor of cellular energy status. Endocrinology 2003; 144: 5179-5183
-
(2003)
Endocrinology
, vol.144
, pp. 5179-5183
-
-
Hardie, D.G.1
-
34
-
-
33845949733
-
Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-Activated protein kinase
-
Suter M, Riek U, Tuerk R, Schlattner U, Wallimann T, Neumann D. Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-Activated protein kinase. J Biol Chem 2006; 281: 32207-32216
-
(2006)
J Biol Chem
, vol.281
, pp. 32207-32216
-
-
Suter, M.1
Riek, U.2
Tuerk, R.3
Schlattner, U.4
Wallimann, T.5
Neumann, D.6
-
35
-
-
70349973869
-
Expanding roles for AMP-Activated protein kinase in neuronal survival and autophagy
-
Poels J, Spasic MR, Callaerts P, Norga KK. Expanding roles for AMP-Activated protein kinase in neuronal survival and autophagy. Bioessays 2009; 31: 944-952
-
(2009)
Bioessays
, vol.31
, pp. 944-952
-
-
Poels, J.1
Spasic, M.R.2
Callaerts, P.3
Norga, K.K.4
-
36
-
-
64349115078
-
AMPK in the brain: Its roles in energy balance and neuroprotection
-
Ronnett GV, Ramamurthy S, Kleman AM, Landree LE, Aja S. AMPK in the brain: Its roles in energy balance and neuroprotection. J Neurochem 2009; 109: 17-23
-
(2009)
J Neurochem
, vol.109
, pp. 17-23
-
-
Ronnett, G.V.1
Ramamurthy, S.2
Kleman, A.M.3
Landree, L.E.4
Aja, S.5
-
37
-
-
0037025356
-
AMP-Activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling
-
Bolster DR, Crozier SJ, Kimball SR, Jefferson LS. AMP-Activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. J Biol Chem 2002; 277: 23977-23980
-
(2002)
J Biol Chem
, vol.277
, pp. 23977-23980
-
-
Bolster, D.R.1
Crozier, S.J.2
Kimball, S.R.3
Jefferson, L.S.4
-
38
-
-
19944408988
-
Activation of AMP-Activated protein kinase (AMPK) inhibits protein syn thesis: A potential strategy to prevent the development of cardiac hypertrophy
-
Chan AY, Dyck Jr. Activation of AMP-Activated protein kinase (AMPK) inhibits protein synthesis: A potential strategy to prevent the development of cardiac hypertrophy. Can J Physiol Pharmacol 2005; 83: 24-28
-
(2005)
Can J Physiol Pharmacol
, vol.83
, pp. 24-28
-
-
Chan, A.Y.1
Dyck, J.R.2
-
39
-
-
17444415304
-
Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside
-
Reiter AK, Bolster DR, Crozier SJ, Kimball SR, Jefferson LS. Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside. Am J Physiol Endocrinol Metab 2005; 288: E980-E988
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Reiter, A.K.1
Bolster, D.R.2
Crozier, S.J.3
Kimball, S.R.4
Jefferson, L.S.5
-
40
-
-
42949139481
-
AMPK phosphorylation of raptor mediates a metabolic checkpoint
-
Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, et al. AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol Cell 2008; 30: 214-226
-
(2008)
Mol Cell
, vol.30
, pp. 214-226
-
-
Gwinn, D.M.1
Shackelford, D.B.2
Egan, D.F.3
Mihaylova, M.M.4
Mery, A.5
Vasquez, D.S.6
-
41
-
-
79960806650
-
Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration
-
Kim SR, Chen X, Oo TF, Kareva T, Yarygina O, Wang C, et al. Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration. Ann Neurol 2011; 70: 110-120
-
(2011)
Ann Neurol
, vol.70
, pp. 110-120
-
-
Kim, S.R.1
Chen, X.2
Oo, T.F.3
Kareva, T.4
Yarygina, O.5
Wang, C.6
-
42
-
-
84856523917
-
AAV transduction of dopamine neurons with constitutively active Rheb protects from neurodegeneration and mediates axon regrowth
-
Kim SR, Kareva T, Yarygina O, Kholodilov N, Burke RE. AAV transduction of dopamine neurons with constitutively active Rheb protects from neurodegeneration and mediates axon regrowth. Mol Ther 2012; 20: 275-286
-
(2012)
Mol Ther
, vol.20
, pp. 275-286
-
-
Kim, S.R.1
Kareva, T.2
Yarygina, O.3
Kholodilov, N.4
Burke, R.E.5
-
43
-
-
34248593475
-
AMP-Activated protein kinase and autophagy
-
Meijer AJ, Codogno P. AMP-Activated protein kinase and autophagy. Autophagy 2007; 3: 238-240
-
(2007)
Autophagy
, vol.3
, pp. 238-240
-
-
Meijer, A.J.1
Codogno, P.2
-
44
-
-
33845924783
-
AMP-Activated protein kinase and the regulation of autophagic proteolysis
-
Meley D, Bauvy C, Houben-Weerts JH, Dubbelhuis PF, Helmond MT, Codogno P, et al. AMP-Activated protein kinase and the regulation of autophagic proteolysis. J Biol Chem 2006; 281: 34870-34879
-
(2006)
J Biol Chem
, vol.281
, pp. 34870-34879
-
-
Meley, D.1
Bauvy, C.2
Houben-Weerts, J.H.3
Dubbelhuis, P.F.4
Helmond, M.T.5
Codogno, P.6
-
45
-
-
41249091730
-
Role of AMP-Activated protein kinase in autophagy and proteasome function
-
Viana R, Aguado C, Esteban I, Moreno D, Viollet B, Knecht E, et al. Role of AMP-Activated protein kinase in autophagy and proteasome function. Biochem Biophys Res Commun 2008; 369: 964-968
-
(2008)
Biochem Biophys Res Commun
, vol.369
, pp. 964-968
-
-
Viana, R.1
Aguado, C.2
Esteban, I.3
Moreno, D.4
Viollet, B.5
Knecht, E.6
-
46
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011; 13: 132-141
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
47
-
-
67650243261
-
Parkin-induced mitophagy in the pathogenesis of Parkinson disease
-
Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin-induced mitophagy in the pathogenesis of Parkinson disease. Autophagy 2009; 5: 706-708
-
(2009)
Autophagy
, vol.5
, pp. 706-708
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
48
-
-
75949098487
-
Pink1-dependent recruitment of parkin to mitochondria in mitophagy
-
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Natl Acad Sci USA 2010; 107: 378-383
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.5
Kim, J.6
-
49
-
-
77950591718
-
AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis
-
Concannon CG, Tuffy LP, Weisova P, Bonner HP, Davila D, Bonner C, et al. AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. J Cell Biol 2010; 189: 83-94
-
(2010)
J Cell Biol
, vol.189
, pp. 83-94
-
-
Concannon, C.G.1
Tuffy, L.P.2
Weisova, P.3
Bonner, H.P.4
Davila, D.5
Bonner, C.6
-
50
-
-
78650941519
-
BH3 domains other than Bim and Bid can directly activate Bax/Bak
-
Du H, Wolf J, Schafer B, Moldoveanu T, Chipuk JE, Kuwana T. BH3 domains other than Bim and Bid can directly activate Bax/Bak. J Biol Chem 2011; 286: 491-501
-
(2011)
J Biol Chem
, vol.286
, pp. 491-501
-
-
Du, H.1
Wolf, J.2
Schafer, B.3
Moldoveanu, T.4
Chipuk, J.E.5
Kuwana, T.6
-
51
-
-
20244362093
-
CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model
-
Chou SY, Lee YC, Chen HM, Chiang MC, Lai HL, Chang HH, et al. CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model. J Neurochem 2005; 93: 310-320
-
(2005)
J Neurochem
, vol.93
, pp. 310-320
-
-
Chou, S.Y.1
Lee, Y.C.2
Chen, H.M.3
Chiang, M.C.4
Lai, H.L.5
Chang, H.H.6
-
52
-
-
20144368904
-
Pharmacological inhibition of AMP-Activated protein kinase provides neuroprotection in stroke
-
McCullough LD, Zeng Z, Li H, Landree LE, McFadden J, Ronnett GV. Pharmacological inhibition of AMP-Activated protein kinase provides neuroprotection in stroke. J Biol Chem 2005; 280: 20493-20502
-
(2005)
J Biol Chem
, vol.280
, pp. 20493-20502
-
-
McCullough, L.D.1
Zeng, Z.2
Li, H.3
Landree, L.E.4
McFadden, J.5
Ronnett, G.V.6
-
53
-
-
33846590099
-
Disturbed cross talk between insulin-like growth factor I and AMP-Activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease
-
Lopez-Lopez C, Dietrich MO, Metzger F, Loetscher H, Torres-Aleman I. Disturbed cross talk between insulin-like growth factor I and AMP-Activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease. J Neurosci 2007; 27: 824-831
-
(2007)
J Neurosci
, vol.27
, pp. 824-831
-
-
Lopez-Lopez, C.1
Dietrich, M.O.2
Metzger, F.3
Loetscher, H.4
Torres-Aleman, I.5
-
54
-
-
79961116788
-
Nuclear translocation of AMPK-Alpha1 potentiates striatal neurodegeneration in Huntington's disease
-
Ju TC, Chen HM, Lin JT, Chang CP, Chang WC, Kang JJ, et al. Nuclear translocation of AMPK-Alpha1 potentiates striatal neurodegeneration in Huntington's disease. J Cell Biol 2011; 194: 209-227
-
(2011)
J Cell Biol
, vol.194
, pp. 209-227
-
-
Ju, T.C.1
Chen, H.M.2
Lin, J.T.3
Chang, C.P.4
Chang, W.C.5
Kang, J.J.6
-
55
-
-
84876078566
-
The camkk2-Ampk kinase pathway mediates the synaptotoxic effects of abeta oligomers through tau phosphorylation
-
Mairet-Coello G, Courchet J, Pieraut S, Courchet V, Maximov A, Polleux F. The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Abeta Oligomers through Tau Phosphorylation. Neuron 2013; 78: 94-108
-
(2013)
Neuron
, vol.78
, pp. 94-108
-
-
Mairet-Coello, G.1
Courchet, J.2
Pieraut, S.3
Courchet, V.4
Maximov, A.5
Polleux, F.6
-
56
-
-
4444383142
-
PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury
-
Hagberg H, Wilson MA, Matsushita H, Zhu C, Lange M, Gustavsson M, et al. PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury. J Neurochem 2004; 90: 1068-1075
-
(2004)
J Neurochem
, vol.90
, pp. 1068-1075
-
-
Hagberg, H.1
Wilson, M.A.2
Matsushita, H.3
Zhu, C.4
Lange, M.5
Gustavsson, M.6
-
57
-
-
33750968870
-
Thin sectioning improves the peak intensity and signal-To-noise ratio in direct tissue mass spectrometry
-
Sugiura Y, Shimma S, Setou M. Thin Sectioning Improves the Peak Intensity and Signal-To-Noise Ratio in Direct Tissue Mass Spectrometry. J Mass Spectrom Soc Jpn 2006; 54: 4
-
(2006)
J Mass Spectrom Soc Jpn
, vol.54
, pp. 4
-
-
Sugiura, Y.1
Shimma, S.2
Setou, M.3
-
58
-
-
0042198976
-
Direct tissue analysis using matrix-Assisted laser desorption/ionization mass spectrometry: Practical aspects of sample preparation
-
Schwartz SA, Reyzer ML, Caprioli RM. Direct tissue analysis using matrix-Assisted laser desorption/ionization mass spectrometry: Practical aspects of sample preparation. J Mass Spectrom 2003; 38: 699-708
-
(2003)
J Mass Spectrom
, vol.38
, pp. 699-708
-
-
Schwartz, S.A.1
Reyzer, M.L.2
Caprioli, R.M.3
-
59
-
-
19444370500
-
Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice
-
Iancu R, Mohapel P, Brundin P, Paul G. Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice. Behav Brain Res 2005; 162: 1-10
-
(2005)
Behav Brain Res
, vol.162
, pp. 1-10
-
-
Iancu, R.1
Mohapel, P.2
Brundin, P.3
Paul, G.4
-
60
-
-
13844269035
-
Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-Treated C57BL/6 mice
-
Mori A, Ohashi S, Nakai M, Moriizumi T, Mitsumoto Y. Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-Treated C57BL/6 mice. Neurosci Res 2005; 51: 265-274
-
(2005)
Neurosci Res
, vol.51
, pp. 265-274
-
-
Mori, A.1
Ohashi, S.2
Nakai, M.3
Moriizumi, T.4
Mitsumoto, Y.5
|