-
1
-
-
84962473762
-
Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1
-
Au Yeung, C. L. et al. Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1. Nat. Commun. 7, 11150 (2016).
-
(2016)
Nat. Commun.
, vol.7
, pp. 11150
-
-
Au Yeung, C.L.1
-
2
-
-
84928779693
-
Enterobacteria-secreted particles induce production of exosomelike S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis
-
Deng, Z. et al. Enterobacteria-secreted particles induce production of exosomelike S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. Nat. Commun. 6, 6956 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 6956
-
-
Deng, Z.1
-
3
-
-
84947723880
-
Tumour exosome integrins determine organotropic metastasis
-
Hoshino, A. et al. Tumour exosome integrins determine organotropic metastasis. Nature 527, 329-335 (2015).
-
(2015)
Nature
, vol.527
, pp. 329-335
-
-
Hoshino, A.1
-
4
-
-
84946559154
-
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth
-
Zhang, L. et al. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature 527, 100-104 (2015).
-
(2015)
Nature
, vol.527
, pp. 100-104
-
-
Zhang, L.1
-
5
-
-
84960337763
-
Communication by extracellular vesicles: Where we are and where we need to go
-
Tkach, M. & Thery, C. Communication by extracellular vesicles: where we are and where we need to go. Cell 164, 1226-1232 (2016).
-
(2016)
Cell
, vol.164
, pp. 1226-1232
-
-
Tkach, M.1
Thery, C.2
-
6
-
-
84953387661
-
Cancer: Diagnosis by extracellular vesicles
-
Thery, C. Cancer: diagnosis by extracellular vesicles. Nature 523, 161-162 (2015).
-
(2015)
Nature
, vol.523
, pp. 161-162
-
-
Thery, C.1
-
7
-
-
84873153440
-
Exosomes and communication between tumours and the immune system: Are all exosomes equal?
-
Bobrie, A. & Thery, C. Exosomes and communication between tumours and the immune system: are all exosomes equal? Biochem. Soc. Trans. 41, 263-267 (2013).
-
(2013)
Biochem. Soc. Trans.
, vol.41
, pp. 263-267
-
-
Bobrie, A.1
Thery, C.2
-
8
-
-
85008708017
-
Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation
-
Bobrie, A., Colombo, M., Krumeich, S., Raposo, G. & Thery, C. Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J. extracell. vesicles 1, 18397 (2012).
-
(2012)
J. Extracell. Vesicles
, vol.1
, pp. 18397
-
-
Bobrie, A.1
Colombo, M.2
Krumeich, S.3
Raposo, G.4
Thery, C.5
-
9
-
-
68849129712
-
Membrane vesicles as conveyors of immune responses
-
Thery, C., Ostrowski, M. & Segura, E. Membrane vesicles as conveyors of immune responses. Nat. rev. Immunol. 9, 581-593 (2009).
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 581-593
-
-
Thery, C.1
Ostrowski, M.2
Segura, E.3
-
10
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
-
Peinado, H. et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat. med. 18, 883-891 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 883-891
-
-
Peinado, H.1
-
11
-
-
84867120348
-
Rab27a supports exosome-dependent and-independent mechanisms that modify the tumor microenvironment and can promote tumor progression
-
Bobrie, A. et al. Rab27a supports exosome-dependent and-independent mechanisms that modify the tumor microenvironment and can promote tumor progression. Cancer res. 72, 4920-4930 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 4920-4930
-
-
Bobrie, A.1
-
12
-
-
40049112564
-
Ceramide triggers budding of exosome vesicles into multivesicular endosomes
-
Trajkovic, K. et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science 319, 1244-1247 (2008).
-
(2008)
Science
, vol.319
, pp. 1244-1247
-
-
Trajkovic, K.1
-
13
-
-
84934435187
-
Noninvasive in vivo monitoring of extracellular vesicles
-
Lai, C. P., Tannous, B. A. & Breakefield, X. O. Noninvasive in vivo monitoring of extracellular vesicles. Meth. mol. biol. 1098, 249-258 (2014).
-
(2014)
Meth. Mol. Biol.
, vol.1098
, pp. 249-258
-
-
Lai, C.P.1
Tannous, B.A.2
Breakefield, X.O.3
-
14
-
-
79952074295
-
Exosomes: Fit to deliver small RNA
-
Zomer, A. et al. Exosomes: fit to deliver small RNA. Commun. integr. biol. 3, 447-450 (2010).
-
(2010)
Commun. Integr. Biol.
, vol.3
, pp. 447-450
-
-
Zomer, A.1
-
15
-
-
84944463735
-
Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
-
Ridder, K. et al. Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment. Oncoimmunology 4, e1008371 (2015).
-
(2015)
Oncoimmunology
, vol.4
-
-
Ridder, K.1
-
16
-
-
84893437162
-
Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter
-
Lai, C. P. et al. Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter. ACS nano 8, 483-494 (2014).
-
(2014)
ACS Nano
, vol.8
, pp. 483-494
-
-
Lai, C.P.1
-
17
-
-
84986631125
-
Plasma exosome microRNAs are indicative of breast cancer
-
Hannafon, B. N. et al. Plasma exosome microRNAs are indicative of breast cancer. Breast cancer res. 18, 90 (2016).
-
(2016)
Breast Cancer Res.
, vol.18
, pp. 90
-
-
Hannafon, B.N.1
-
18
-
-
84950128619
-
Exosomes in cancer disease
-
Zoller, M. Exosomes in cancer disease. Meth. mol. biol. 1381, 111-149 (2016).
-
(2016)
Meth. Mol. Biol.
, vol.1381
, pp. 111-149
-
-
Zoller, M.1
-
19
-
-
84957808674
-
Meeting report: Discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium
-
Laurent, L. C. et al. Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium. J. extracell. vesicles 4, 26533 (2015).
-
(2015)
J. Extracell. Vesicles
, vol.4
, pp. 26533
-
-
Laurent, L.C.1
-
20
-
-
84931287779
-
Serum exosome microRNA as a minimally-invasive early biomarker of AML
-
Hornick, N. I. et al. Serum exosome microRNA as a minimally-invasive early biomarker of AML. Sci. rep. 5, 11295 (2015).
-
(2015)
Sci. Rep.
, vol.5
, pp. 11295
-
-
Hornick, N.I.1
-
21
-
-
84929224664
-
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
-
Shao, H. et al. Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma. Nat. commun. 6, 6999 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 6999
-
-
Shao, H.1
-
22
-
-
57049103401
-
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
-
Skog, J. et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. cell biol. 10, 1470-1476 (2008).
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1470-1476
-
-
Skog, J.1
-
23
-
-
84967018517
-
Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages
-
Teng, Y. et al. Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages. Oncotarget 7, 25683-25697 (2016).
-
(2016)
Oncotarget
, vol.7
, pp. 25683-25697
-
-
Teng, Y.1
-
24
-
-
84999015873
-
Exosomal miRNAs as cancer biomarkers and therapeutic targets
-
Thind, A. & Wilson, C. Exosomal miRNAs as cancer biomarkers and therapeutic targets. J. extracell. vesicles 5, 31292 (2016).
-
(2016)
J. Extracell. Vesicles
, vol.5
, pp. 31292
-
-
Thind, A.1
Wilson, C.2
-
25
-
-
84957690976
-
Exosomal miRNAs as biomarkers of recurrent lung cancer
-
Munagala, R., Aqil, F. & Gupta, R. C. Exosomal miRNAs as biomarkers of recurrent lung cancer. Tumour biol. 37, 10703-10714 (2016).
-
(2016)
Tumour Biol.
, vol.37
, pp. 10703-10714
-
-
Munagala, R.1
Aqil, F.2
Gupta, R.C.3
-
26
-
-
84944463325
-
Exosomal levels of miRNA-21 from cerebrospinal fluids associated with poor prognosis and tumor recurrence of glioma patients
-
Shi, R. et al. Exosomal levels of miRNA-21 from cerebrospinal fluids associated with poor prognosis and tumor recurrence of glioma patients. Oncotarget 6, 26971-26981 (2015).
-
(2015)
Oncotarget
, vol.6
, pp. 26971-26981
-
-
Shi, R.1
-
27
-
-
84931578325
-
Circulating serum exosomal miRNAs as potential biomarkers for esophageal adenocarcinoma
-
Chiam, K. et al. Circulating serum exosomal miRNAs as potential biomarkers for esophageal adenocarcinoma. J. gastrointest. surg. 19, 1208-1215 (2015).
-
(2015)
J. Gastrointest. Surg.
, vol.19
, pp. 1208-1215
-
-
Chiam, K.1
-
28
-
-
84938957970
-
Exosomal onco-miRs from serum of patients with adenocarcinoma of the esophagus: Comparison of miRNA profiles of exosomes and matching tumor
-
Warnecke-Eberz, U., Chon, S. H., Holscher, A. H., Drebber, U. & Bollschweiler, E. Exosomal onco-miRs from serum of patients with adenocarcinoma of the esophagus: comparison of miRNA profiles of exosomes and matching tumor. Tumour biol. 36, 4643-4653 (2015).
-
(2015)
Tumour Biol.
, vol.36
, pp. 4643-4653
-
-
Warnecke-Eberz, U.1
Chon, S.H.2
Holscher, A.H.3
Drebber, U.4
Bollschweiler, E.5
-
29
-
-
84897046745
-
MiRNA in melanoma-derived exosomes
-
Gajos-Michniewicz, A., Duechler, M. & Czyz, M. MiRNA in melanoma-derived exosomes. Cancer lett. 347, 29-37 (2014).
-
(2014)
Cancer Lett.
, vol.347
, pp. 29-37
-
-
Gajos-Michniewicz, A.1
Duechler, M.2
Czyz, M.3
-
30
-
-
84885161300
-
Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma
-
Aushev, V. N. et al. Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma. PLoS ONE 8, e78649 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Aushev, V.N.1
-
31
-
-
84884171136
-
MicroRNA and protein profiling of brain metastasis competent cell-derived exosomes
-
Camacho, L., Guerrero, P. & Marchetti, D. MicroRNA and protein profiling of brain metastasis competent cell-derived exosomes. PLoS ONE 8, e73790 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Camacho, L.1
Guerrero, P.2
Marchetti, D.3
-
32
-
-
84884765359
-
Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies
-
Chugh, P. E. et al. Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies. PLoS pathog. 9, e1003484 (2013).
-
(2013)
PLoS Pathog.
, vol.9
-
-
Chugh, P.E.1
-
33
-
-
45449093192
-
MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
-
Taylor, D. D. & Gercel-Taylor, C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol. oncol. 110, 13-21 (2008).
-
(2008)
Gynecol. Oncol.
, vol.110
, pp. 13-21
-
-
Taylor, D.D.1
Gercel-Taylor, C.2
-
34
-
-
84930170395
-
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
-
Costa-Silva, B. et al. Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver. Nat. cell biol. 17, 816-826 (2015).
-
(2015)
Nat. Cell Biol.
, vol.17
, pp. 816-826
-
-
Costa-Silva, B.1
-
35
-
-
84904704297
-
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles
-
Colombo, M., Raposo, G. & Thery, C. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Ann. rev. cell dev. biol. 30, 255-289 (2014).
-
(2014)
Ann. Rev. Cell Dev. Biol.
, vol.30
, pp. 255-289
-
-
Colombo, M.1
Raposo, G.2
Thery, C.3
-
36
-
-
85013222187
-
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
-
Witwer, K. W. et al. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J. extracell. vesicles 2, 20360 (2013).
-
(2013)
J. Extracell. Vesicles
, vol.2
, pp. 20360
-
-
Witwer, K.W.1
-
37
-
-
43249109372
-
Isolation and characterization of exosomes from cell culture supernatants and biological fluids
-
Thery, C., Amigorena, S., Raposo, G. & Clayton, A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr. protoc. cell biol. 30:3.22, 3.22.1-3.22.29 (2006).
-
(2006)
Curr. Protoc. Cell Biol.
, vol.30
, Issue.3-22
, pp. 3221-32229
-
-
Thery, C.1
Amigorena, S.2
Raposo, G.3
Clayton, A.4
-
38
-
-
84960403826
-
Association of single nucleotide polymorphisms in the MVP gene with platinum resistance and survival in patients with epithelial ovarian cancer
-
Zhao, Y. N., He, D. N., Wang, Y. D., Li, J. J. & Ha, M. W. Association of single nucleotide polymorphisms in the MVP gene with platinum resistance and survival in patients with epithelial ovarian cancer. Oncol. lett. 11, 2925-2933 (2016).
-
(2016)
Oncol. Lett.
, vol.11
, pp. 2925-2933
-
-
Zhao, Y.N.1
He, D.N.2
Wang, Y.D.3
Li, J.J.4
Ha, M.W.5
-
39
-
-
84880712720
-
Major vault protein (MVP) gene polymorphisms and drug resistance in mesial temporal lobe epilepsy with hippocampal sclerosis
-
Balan, S. et al. Major vault protein (MVP) gene polymorphisms and drug resistance in mesial temporal lobe epilepsy with hippocampal sclerosis. Gene 526, 449-453 (2013).
-
(2013)
Gene
, vol.526
, pp. 449-453
-
-
Balan, S.1
-
41
-
-
34548587400
-
Biological comparison of ovarian cancer resistant cell lines to cisplatin and taxol by two different administrations
-
Yan, X. D., Li, M., Yuan, Y., Mao, N. & Pan, L. Y. Biological comparison of ovarian cancer resistant cell lines to cisplatin and taxol by two different administrations. Oncol. rep. 17, 1163-1169 (2007).
-
(2007)
Oncol. Rep.
, vol.17
, pp. 1163-1169
-
-
Yan, X.D.1
Li, M.2
Yuan, Y.3
Mao, N.4
Pan, L.Y.5
-
42
-
-
33644905041
-
Vascular colocalization of P-glycoprotein, multidrugresistance associated protein 1, breast cancer resistance protein and major vault protein in human epileptogenic pathologies
-
Sisodiya, S. M. et al. Vascular colocalization of P-glycoprotein, multidrugresistance associated protein 1, breast cancer resistance protein and major vault protein in human epileptogenic pathologies. Neuropathol. appl. neurobiol. 32, 51-63 (2006).
-
(2006)
Neuropathol. Appl. Neurobiol.
, vol.32
, pp. 51-63
-
-
Sisodiya, S.M.1
-
43
-
-
21344472578
-
Major vault protein, in concert with constitutively photomorphogenic 1, negatively regulates c-Jun-mediated activator protein 1 transcription in mammalian cells
-
Yi, C. et al. Major vault protein, in concert with constitutively photomorphogenic 1, negatively regulates c-Jun-mediated activator protein 1 transcription in mammalian cells. Cancer res. 65, 5835-5840 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 5835-5840
-
-
Yi, C.1
-
44
-
-
3142751435
-
The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signaling
-
Kolli, S., Zito, C. I., Mossink, M. H., Wiemer, E. A. & Bennett, A. M. The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signaling. J. biol. chem. 279, 29374-29385 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29374-29385
-
-
Kolli, S.1
Zito, C.I.2
Mossink, M.H.3
Wiemer, E.A.4
Bennett, A.M.5
-
45
-
-
0345688213
-
Vaults: A ribonucleoprotein particle involved in drug resistance?
-
Mossink, M. H., van Zon, A., Scheper, R. J., Sonneveld, P. & Wiemer, E. A. Vaults: a ribonucleoprotein particle involved in drug resistance? Oncogene 22, 7458-7467 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 7458-7467
-
-
Mossink, M.H.1
Van Zon, A.2
Scheper, R.J.3
Sonneveld, P.4
Wiemer, E.A.5
-
46
-
-
85009110248
-
Crystal structure of a dimerization domain of human Caprin-1: Insights into the assembly of an evolutionarily conserved ribonucleoprotein complex consisting of Caprin-1, FMRP and G3BP1
-
Wu, Y., Zhu, J., Huang, X. & Du, Z. Crystal structure of a dimerization domain of human Caprin-1: insights into the assembly of an evolutionarily conserved ribonucleoprotein complex consisting of Caprin-1, FMRP and G3BP1. Acta Crystallogr. D Struct. Biol. 72, 718-727 (2016).
-
(2016)
Acta Crystallogr. D Struct. Biol.
, vol.72
, pp. 718-727
-
-
Wu, Y.1
Zhu, J.2
Huang, X.3
Du, Z.4
-
47
-
-
84922998508
-
Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: An identification of a novel oncotarget
-
Qiu, Y. Q. et al. Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget. Oncotarget 6, 2148-2163 (2015).
-
(2015)
Oncotarget
, vol.6
, pp. 2148-2163
-
-
Qiu, Y.Q.1
-
48
-
-
33947210861
-
Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs
-
Solomon, S. et al. Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs. Mol. cell. biol. 27, 2324-2342 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 2324-2342
-
-
Solomon, S.1
-
49
-
-
79953136097
-
Rab27a and Rab27b control different steps of the exosome secretion pathway
-
Ostrowski, M. et al. Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat. cell biol. 12, 19-30 sup. 1-13 (2010).
-
(2010)
Nat. Cell Biol.
, vol.12
, Issue.19-30
, pp. 1-13
-
-
Ostrowski, M.1
-
50
-
-
84961410388
-
MiR-193a-3p and miR-193a-5p suppress the metastasis of human osteosarcoma cells by down-regulating Rab27B and SRR, respectively
-
Pu, Y. et al. MiR-193a-3p and miR-193a-5p suppress the metastasis of human osteosarcoma cells by down-regulating Rab27B and SRR, respectively. Clin. exp. metastasis 33, 359-372 (2016).
-
(2016)
Clin. Exp. Metastasis
, vol.33
, pp. 359-372
-
-
Pu, Y.1
-
51
-
-
79961168650
-
MiR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT
-
Xiang, X. et al. miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. Oncogene 30, 3440-3453 (2011).
-
(2011)
Oncogene
, vol.30
, pp. 3440-3453
-
-
Xiang, X.1
-
52
-
-
65349196684
-
COP9-associated CSN5 regulates exosomal protein deubiquitination and sorting
-
Liu, Y. et al. COP9-associated CSN5 regulates exosomal protein deubiquitination and sorting. Am. j. pathol. 174, 1415-1425 (2009).
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 1415-1425
-
-
Liu, Y.1
|