Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1

Nature Communications

Volumn 7, Issue , 2016, Pages

  Au Yeung, Chi Lam ^a   Co, Ngai Na ^a   Tsuruga, Tetsushi ^a   Yeung, Tsz Lun ^a   Kwan, Suet Ying ^a   Leung, Cecilia S ^a   Li, Yong ^b   Lu, Edward S ^a   Kwan, Kenny ^a   Wong, Kwong Kwok ^a   Schmandt, Rosemarie ^a   Lu, Karen H ^a   Mok, Samuel C ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALPHA SMOOTH MUSCLE ACTIN; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CD63 ANTIGEN; HEAT SHOCK PROTEIN 70; MESSENGER RNA; MICRORNA 21; PACLITAXEL; MICRORNA; MIRN21 MICRORNA, HUMAN;

APOPTOSIS; CANCER; CELLS AND CELL COMPONENTS; CHEMOTHERAPY; DRUG RESISTANCE; PHENOTYPE; PROTEIN; TUMOR;

ADIPOCYTE; ARTICLE; CANCER ASSOCIATED ADIPOCYTE; CANCER ASSOCIATED FIBROBLAST; CANCER CELL CULTURE; CANCER RESISTANCE; CELL PROLIFERATION; CONTROLLED STUDY; EXOSOME; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NEXT GENERATION SEQUENCING; OVARY CANCER; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL; TUMOR INVASION; TUMOR MICROENVIRONMENT; WESTERN BLOTTING; APOPTOSIS; CELL MOTION; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; OVARIAN NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ADIPOCYTES; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; EXOSOMES; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; NEOPLASM INVASIVENESS; OVARIAN NEOPLASMS; PACLITAXEL; STROMAL CELLS;

EID: 84962473762     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11150     Document Type: Article

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