PARK2-dependent mitophagy induced by acidic postconditioning protects against focal cerebral ischemia and extends the reperfusion window

Autophagy

Volumn 13, Issue 3, 2017, Pages 473-485

  Shen, Zhe ^a   Zheng, Yanrong ^a   Wu, Jiaying ^a   Chen, Ying ^a   Wu, Xiaoli ^a   Zhou, Yiting ^a   Yuan, Yang ^a   Lu, Shousheng ^a   Jiang, Lei ^a   Qin, Zhenghong ^b   Chen, Zhong ^a   Hu, Weiwei ^a   Zhang, Xiangnan ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

Author keywords

acidic postconditioning; cerebral ischemia; mitophagy; neuroprotection; PARK2; time window

Indexed keywords

ADENOSINE TRIPHOSPHATE; AUTOPHAGY RELATED PROTEIN 7; BIOLOGICAL MARKER; CARBON DIOXIDE; COX4I1 PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 1; MITOCHONDRIAL DNA; PARKIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TOMM20 PROTEIN; TRANSCRIPTION FACTOR NRF1; UNCLASSIFIED DRUG; UBIQUITIN PROTEIN LIGASE;

ACIDIC POSTCONDITIONING; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; BRAIN NERVE CELL; BRAIN PERFUSION; BRAIN SLICE; BREATHING RATE; CONTROLLED STUDY; ISCHEMIC POSTCONDITIONING; KNOCKOUT MOUSE; MALE; MITOPHAGY; MOUSE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; REPERFUSION; ANIMAL; BRAIN; C57BL MOUSE; CELL CULTURE; CEREBRAL ARTERY DISEASE; COMPLICATION; DEFICIENCY; METABOLISM; MITOCHONDRION; NERVE CELL; PATHOLOGY; PROTEIN TRANSPORT; REPERFUSION INJURY; VASCULARIZATION;

ANIMALS; BRAIN; BRAIN ISCHEMIA; CARBON DIOXIDE; CELLS, CULTURED; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC POSTCONDITIONING; MALE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; NEURONS; NEUROPROTECTION; PROTEIN TRANSPORT; REPERFUSION INJURY; UBIQUITIN-PROTEIN LIGASES;

EID: 85013127736     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1274596     Document Type: Article

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