Interdependence of parkin-mediated mitophagy and mitochondrial fission in adult mouse hearts

Circulation Research

Volumn 117, Issue 4, 2015, Pages 346-351

  Song, Moshi ^a   Gong, Guohua ^a   Burelle, Yan ^b   Gustafsson, Åsa B ^c   Kitsis, Richard N ^d   Matkovich, Scot J ^a   Dorn, Gerald W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Cardiomyopathies; Mice; Mitochondria; Mitochondrial degradation; Mitochondrial dynamics; Parkin protein

Indexed keywords

CELL MEMBRANE PROTEIN; DYNAMIN; DYNAMIN RELATED PROTEIN 1; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; MITOCHONDRIAL PROTEIN; PARKIN; SQSTM1 PROTEIN; UNCLASSIFIED DRUG; DNM1L PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGOSOME; CARDIOMYOPATHY; CELL DEATH; CELL INTERACTION; CONTROLLED STUDY; GENE DELETION; GENE OVEREXPRESSION; GENE REPRESSION; HEART; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART PRESERVATION; HEART VENTRICLE EJECTION; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL FISSION; MITOPHAGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR UPREGULATION; SURVIVAL RATE; UBIQUITINATION; ANIMAL; DEFICIENCY; FIBROSIS; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART VENTRICLE REMODELING; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRIAL DYNAMICS; NECROSIS; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; TIME; ULTRASTRUCTURE;

ANIMALS; CARDIOMYOPATHIES; DYNAMINS; FIBROSIS; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL DYNAMICS; MYOCARDIUM; NECROSIS; PHENOTYPE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; UBIQUITIN-PROTEIN LIGASES; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84941741215     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.117.306859     Document Type: Article

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