Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes

Diabetologia

Volumn 60, Issue 7, 2017, Pages 1294-1303

  Willcox, Abby ^a   Richardson, Sarah J ^b   Walker, Lucy S K ^c   Kent, Sally C ^d   Morgan, Noel G ^b   Gillespie, Kathleen M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Histology; Islet autoimmunity; Pancreatic lymph nodes; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; CD20 ANTIGEN; CD3 ANTIGEN; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; KI 67 ANTIGEN; AUTOANTIGEN; INSULIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CELL DESTRUCTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; FEMALE; FOLLICULAR DENDRITIC CELL; GERMINAL CENTER; HIGH RISK POPULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; MALE; NERVE CELL NETWORK; PANCREAS ISLET BETA CELL; PANCREATIC LYMPH NODE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; TISSUE SECTION; YOUNG ADULT; ANIMAL; B LYMPHOCYTE; COHORT ANALYSIS; CYTOLOGY; DENDRITIC CELL; FLUORESCENCE MICROSCOPY; GOAT; IMAGE PROCESSING; IMMUNOLOGY; LEPORIDAE; LYMPH NODE; METABOLISM; MOUSE; PANCREAS; PANCREAS ISLET; PATHOLOGY; PHENOTYPE;

ADOLESCENT; ADULT; AGED; ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; B-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; FEMALE; GERMINAL CENTER; GOATS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; KI-67 ANTIGEN; LYMPH NODES; MALE; MICE; MICROSCOPY, FLUORESCENCE; PANCREAS; PHENOTYPE; RABBITS; YOUNG ADULT;

EID: 85013113118     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-017-4221-7     Document Type: Article

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