IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients

Diabetologia

Volumn 58, Issue 4, 2015, Pages 781-790

  Ferreira, Ricardo C ^a   Simons, Henry Z ^a   Thompson, Whitney S ^a   Cutler, Antony J ^a   Dopico, Xaquin Castro ^a   Smyth, Deborah J ^a   Mashar, Meghavi ^a   Schuilenburg, Helen ^a   Walker, Neil M ^a   Dunger, David B ^b   Wallace, Chris ^a   Todd, John A ^a   Wicker, Linda S ^a   Pekalski, Marcin L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Human; IFN ; IL 17; IL 21; Immunophenotyping; T follicular helper cell; Type 1 diabetes

Indexed keywords

CD45RA ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 21; BIOLOGICAL MARKER; IFNG PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETIC PATIENT; DIABETOGENESIS; EFFECTOR CELL; FLOW CYTOMETRY; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; INSULIN DEPENDENT DIABETES MELLITUS; MEMORY T LYMPHOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; ADOLESCENT; CASE CONTROL STUDY; CELL CULTURE; CHILD; DIABETES MELLITUS, TYPE 1; FEMALE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; MALE; METABOLISM; MIDDLE AGED; UPREGULATION; YOUNG ADULT;

ADOLESCENT; ADULT; BIOMARKERS; CASE-CONTROL STUDIES; CELLS, CULTURED; CHILD; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKINS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; T-LYMPHOCYTES, HELPER-INDUCER; UP-REGULATION; YOUNG ADULT;

EID: 84925490425     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3509-8     Document Type: Article

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