A critical role for lymphotoxin-β receptor in the development of diabetes in nonobese diabetic mice

Journal of Experimental Medicine

Volumn 193, Issue 11, 2001, Pages 1333-1339

  Ettinger, Rachel ^a   Munson, Sibyl H ^b   Chao, Cheng Chi ^c   Vadeboncoeur, Mary ^b   Toma, Jon ^b   McDevitt, Hugh O ^b  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Nuvelo Inc   (United States)

Author keywords

Autoimmune disease; LIGHT; Lymphoid development; Marginal zone; Tumor necrosis factor

Indexed keywords

LYMPHOTOXIN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; AUTOIMMUNITY; COMPLEX FORMATION; CYTOARCHITECTURE; DENDRITIC CELL; DIABETES MELLITUS; GENE DISRUPTION; GERMINAL CENTER; MEDIATOR RELEASE; MOUSE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

ANIMALS; DIABETES MELLITUS, TYPE 1; FEMALE; GERMINAL CENTER; GLUTAMATE DECARBOXYLASE; ISLETS OF LANGERHANS; LYMPHOTOXIN BETA RECEPTOR; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED NOD; RECEPTORS, TUMOR NECROSIS FACTOR;

EID: 0035806278     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.11.1333     Document Type: Article

References (15)

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3. A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation
4. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family
5. LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator
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7. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues
8. Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice
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11. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
12. IgG effector mechanisms
13. Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes
14. Involvement of beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in obese diabetic mice
15. Vascular addressins are induced on islet vessels during insulitis in nonobese diabetic mice and are involved in lymphoid cell binding to islet endothelium