Heterogeneity of human Ro ribonucleoproteins (RNPS): Nuclear retention of Ro RNPS containing the human hY5 RNA in human and mouse cells

Clinical and Experimental Immunology

Volumn 125, Issue 1, 2001, Pages 162-168

  Gendron, M ^a   Roberge, D ^a   Boire, G ^a  

^a CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE   (Canada)

Author keywords

Anti Ro antibodies; Autoantigens; Cytolocalization; Ribonucleoprotein; Ro antigen transfection

Indexed keywords

AUTOANTIGEN; RIBONUCLEOPROTEIN; RO RIBONUCLEOPROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; SEQUENCE ANALYSIS;

3T3 CELLS; ANIMALS; AUTOANTIGENS; CELL NUCLEUS; CYTOPLASM; GENE EXPRESSION; GENETIC HETEROGENEITY; HELA CELLS; HUMANS; MICE; PRECIPITIN TESTS; RIBONUCLEOPROTEINS; RNA; RNA, SMALL CYTOPLASMIC;

EID: 0034904265     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2001.01566.x     Document Type: Article

References (36)

1. Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology
2. Rheumatoid arthritis: Anti-Ro antibodies define a non-HLA-DR4 associated clinicoserological cluster
3. MRL/lpr mice produce anti-Ro 52 000 MW antibodies: Detection, analysis of specificity and site of production
4. The immune response to 52-kDa Ro and 60-kDa Ro is linked in experimental autoimmunity
5. Intra- and intermolecular spreading of autoimmunity involving the nuclear self-antigens La (SS-B) and Ro (SS-A)
6. The Ro small cytoplasmic ribonucleoproteins: Identification of the antigenic protein and its binding site on the Ro RNAs
7. hY5 particle
8. Gene encoding human Ro-associated autoantigen Y5 RNA
9. Human Ro ribonucleoprotein particles: Characterization of native structure and stable association with the La polypeptide
10. Binding of the 60-kDa Ro autoantigen to Y RNAs: Evidence for recognition in the major groove of a conserved helix
11. Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: Further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells
12. Analysis of the intracellular localization and assembly of Ro ribonucleoprotein particles by microinjection into Xenopus laevis oocytes
13. A perinucleolar compartment contains several RNA polymerase III transcripts as well as the polypyrimidine tract-binding protein, hnRNP I
14. The ultrastructural localization of 60-kDa Ro protein and human cytoplasmic RNAs: Association with novel electron-dense bodies
15. Intracellular localization and nucleocytoplasmic transport of Ro RNP components
16. The interactions with Ro60 and La differentially affect nuclear export of hY1 RNA
17. Cytoplasmic assembly and nuclear accumulation of mature small nuclear ribonucleoprotein particles
18. Cellular localization of the target structures recognized by the anti-Jo-1 antibody: Immunofluorescence studies on cultured human myoblasts
19. Autoantigenic epitopes on hY5 Ro RNA are distinct from regions bound by the 60-kDa Ro and La proteins
20. Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
21. The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors
22. Cholesterol and the Golgi apparatus
23. The Ro ribonucleoprotein particle: Induction of autoantibodies and the detection of Ro RNAs among species
24. Purification of antigenically intact Ro ribonucleoproteins; biochemical and immunological evidence that the 52-kD protein is not a Ro protein
25. The human Y4 small cytoplasmic RNA gene is controlled by upstream elements and resides on chromosome 7 with all other hY scRNA genes
26. Phosphorylation of the human La antigen on serine 366 can regulate recycling of RNA polymerase III transcription complexes
27. Phosphorylation profiles of 60-kD Ro antigen in synchronized HEp-2 cells
28. Interaction cloning and characterization of RoBPI, a novel protein binding to human Ro ribonucleoproteins
29. A possible role for the 60-kD Ro autoantigen in a discard pathway for defective 5S rRNA precursors
30. A misfolded form of 5S rRNA is complexed with the Ro and La autoantigens
31. The levels of the RoRNP-associated Y RNA are dependent upon the presence of RoP-1, the Caenorhabditis elegans Ro60 protein
32. Involvement of the Xenopus laevis Ro60 autoantigen in the alternative interaction of La and CNBP proteins with the 5′UTR of L4 ribosomal protein mRNA
33. Identification of ribonucleoprotein (RNP)-specific protein interactions using a yeast RNP interaction trap assay (RITA)
34. PUF60: A novel U2AF65-related splicing activity
35. The FBP interacting repressor targets TFIIH to inhibit activated transcription
36. Autoantibodies in human anti-Ro sera specifically recognize deproteinized hY5 Ro RNA