Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity

Redox Biology

Volumn 12, Issue , 2017, Pages 58-69

  Prasad, Shikha ^a   Sajja, Ravi K ^a   Kaisar, Mohammad Abul ^a   Park, Jee Hyun ^a   Villalba, Heidi ^a   Liles, Taylor ^a   Abbruscato, Thomas ^a   Cucullo, Luca ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Blood brain barrier; Blood hemostasis; Cigarette smoke; Glucose transporter; Metformin; Nrf2; Oxidative stress; Tight junctions

Indexed keywords

GLUCOSE TRANSPORTER 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; THROMBOMODULIN; TIGHT JUNCTION PROTEIN; TRANSCRIPTION FACTOR NRF2; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CEREBROVASCULAR DISEASE; CEREBROVASCULAR TOXICITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; INFLAMMATION; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TOBACCO; ANIMAL; BRAIN; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; ENDOTHELIUM CELL; METABOLISM; SIGNAL TRANSDUCTION; SMOKE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; METFORMIN; MICE; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SMOKE; TOBACCO;

EID: 85012271492     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2017.02.007     Document Type: Article

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