-
2
-
-
84876222876
-
Clinical and pharmacologic aspects of blinatumomab in the treatment of B-cell acute lymphoblastic leukemia
-
Portell CA, Wenzell CM, Advani AS. Clinical and pharmacologic aspects of blinatumomab in the treatment of B-cell acute lymphoblastic leukemia. Clin Pharmacol 2013;5:5-11.
-
(2013)
Clin Pharmacol
, vol.5
, pp. 5-11
-
-
Portell, C.A.1
Wenzell, C.M.2
Advani, A.S.3
-
3
-
-
84940379637
-
Adoptive cell therapy-tumor-infiltrating lymphocytes, Tcell receptors, and chimeric antigen receptors
-
Feldman SA, Assadipour Y, Kriley I, et al. Adoptive cell therapy-tumor-infiltrating lymphocytes, Tcell receptors, and chimeric antigen receptors. Semin Oncol 2015;42:626-639.
-
(2015)
Semin Oncol
, vol.42
, pp. 626-639
-
-
Feldman, S.A.1
Assadipour, Y.2
Kriley, I.3
-
4
-
-
84908299844
-
Effective response and delayed toxicities of refractory advanced diffuse large B-cell lymphoma treated by CD20-directed chimeric antigen receptor-modified T cells
-
Wang Y, Zhang WY, Han QW, et al. Effective response and delayed toxicities of refractory advanced diffuse large B-cell lymphoma treated by CD20-directed chimeric antigen receptor-modified T cells. Clin Immunol 2014;155:160-175.
-
(2014)
Clin Immunol
, vol.155
, pp. 160-175
-
-
Wang, Y.1
Zhang, W.Y.2
Han, Q.W.3
-
5
-
-
84979240618
-
Nivolumab in patients with relapsed or refractory hematologic malignancy: Preliminary results of a Phase Ib study
-
Lesokhin AM, Ansell SM, Armand P, et al. Nivolumab in patients with relapsed or refractory hematologic malignancy: preliminary results of a Phase Ib study. J Clin Oncol 2016;34:2698-2704.
-
(2016)
J Clin Oncol
, vol.34
, pp. 2698-2704
-
-
Lesokhin, A.M.1
Ansell, S.M.2
Armand, P.3
-
6
-
-
84941038106
-
Synthetic immunity to break down the bottleneck of cancer immunotherapy
-
Chen ZY, Ma F, Huang H, et al. Synthetic immunity to break down the bottleneck of cancer immunotherapy. Sci Bull 2015;60:977-985.
-
(2015)
Sci Bull
, vol.60
, pp. 977-985
-
-
Chen, Z.Y.1
Ma, F.2
Huang, H.3
-
7
-
-
84950989868
-
Bispecific antibodies and their applications
-
Fan G, Wang Z, Hao M, et al. Bispecific antibodies and their applications. J Hematol Oncol 2015;8:130.
-
(2015)
J Hematol Oncol
, vol.8
, pp. 130
-
-
Fan, G.1
Wang, Z.2
Hao, M.3
-
9
-
-
84865115651
-
Trifunctional bispecific antibodies induce tumor-specific T cells and elicit a vaccination effect
-
Eissler N, Ruf P, Mysliwietz J, et al. Trifunctional bispecific antibodies induce tumor-specific T cells and elicit a vaccination effect. Cancer Res 2012;72:3958-3966.
-
(2012)
Cancer Res
, vol.72
, pp. 3958-3966
-
-
Eissler, N.1
Ruf, P.2
Mysliwietz, J.3
-
10
-
-
49649120397
-
Tumor regression in cancer patients by very low doses of a T cellengaging antibody
-
Bargou R, Leo E, Zugmaier G, et al. Tumor regression in cancer patients by very low doses of a T cellengaging antibody. Science 2008;321:974-977.
-
(2008)
Science
, vol.321
, pp. 974-977
-
-
Bargou, R.1
Leo, E.2
Zugmaier, G.3
-
11
-
-
0037040433
-
Efficient inhibition of human B-cell lymphoma xenografts with an anti- CD20? Anti-CD3 bispecific diabody
-
Xiong D, Xu Y, Liu H, et al. Efficient inhibition of human B-cell lymphoma xenografts with an anti- CD20 ? anti-CD3 bispecific diabody. Cancer Lett 2002;177:29-39.
-
(2002)
Cancer Lett
, vol.177
, pp. 29-39
-
-
Xiong, D.1
Xu, Y.2
Liu, H.3
-
12
-
-
84973365059
-
Improved antileukemia activities of adoptively transferred T cells expressing bispecific T-cell engager in mice
-
Liu X, Barrett DM, Jiang S, et al. Improved antileukemia activities of adoptively transferred T cells expressing bispecific T-cell engager in mice. Blood Cancer J 2016;6:e430.
-
(2016)
Blood Cancer J
, vol.6
, pp. e430
-
-
Liu, X.1
Barrett, D.M.2
Jiang, S.3
-
13
-
-
84973352594
-
T cells expressing CD19-specific engager molecules for the immunotherapy of CD19-positive malignancies
-
Velasquez MP, Torres D, Iwahori K, et al. T cells expressing CD19-specific engager molecules for the immunotherapy of CD19-positive malignancies. Sci Rep 2016;6:27130.
-
(2016)
Sci Rep
, vol.6
, pp. 27130
-
-
Velasquez, M.P.1
Torres, D.2
Iwahori, K.3
-
14
-
-
84986295402
-
TIFA suppresses hepatocellular carcinoma progression via MALT1- dependent and -independent signaling pathways
-
Shen W, Du R, Li J, et al. TIFA suppresses hepatocellular carcinoma progression via MALT1- dependent and -independent signaling pathways. Signal Transduct Target Ther 2016;1:16013.
-
(2016)
Signal Transduct Target Ther
, vol.1
, pp. 16013
-
-
Shen, W.1
Du, R.2
Li, J.3
-
15
-
-
28944434529
-
Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells
-
Offner S, Hofmeister R, Romaniuk A, et al. Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells. Mol Immunol 2006;43:763-771.
-
(2006)
Mol Immunol
, vol.43
, pp. 763-771
-
-
Offner, S.1
Hofmeister, R.2
Romaniuk, A.3
-
16
-
-
84905993539
-
Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors
-
Moon EK, Wang LC, Dolfi DV, et al. Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors. Clin Cancer Res 2014;20:4262-4273.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 4262-4273
-
-
Moon, E.K.1
Wang, L.C.2
Dolfi, D.V.3
-
17
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
Grupp SA, Kalos M, Barrett D, et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. New Engl J Med 2013;368:1509-1518.
-
(2013)
New Engl J Med
, vol.368
, pp. 1509-1518
-
-
Grupp, S.A.1
Kalos, M.2
Barrett, D.3
-
18
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptortransduced T cells
-
Kochenderfer JN, Dudley ME, Feldman SA, et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptortransduced T cells. Blood 2012;119:2709-2720.
-
(2012)
Blood
, vol.119
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
-
19
-
-
84957647658
-
Harnessing T cells to fight cancer with BiTE(R) antibody constructs-past developments and future directions
-
Klinger M, Benjamin J, Kischel R, et al. Harnessing T cells to fight cancer with BiTE(R) antibody constructs-past developments and future directions. Immunol Rev 2016;270:193-208.
-
(2016)
Immunol Rev
, vol.270
, pp. 193-208
-
-
Klinger, M.1
Benjamin, J.2
Kischel, R.3
-
20
-
-
20144387546
-
Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/ CD3-bispecific antibody construct
-
Schlereth B, Fichtner I, Lorenczewski G et al. Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/ CD3-bispecific antibody construct. Cancer Res 2005;65:2882-2889.
-
(2005)
Cancer Res
, vol.65
, pp. 2882-2889
-
-
Schlereth, B.1
Fichtner, I.2
Lorenczewski, G.3
-
21
-
-
84920691639
-
Engager T cells: A new class of antigen-specific T cells that redirect bystander T cells
-
Iwahori K, Kakarla S, Velasquez MP et al. Engager T cells: a new class of antigen-specific T cells that redirect bystander T cells. Mol Ther 2015;23:171-178.
-
(2015)
Mol Ther
, vol.23
, pp. 171-178
-
-
Iwahori, K.1
Kakarla, S.2
Velasquez, M.P.3
-
22
-
-
0041315884
-
Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
-
Chen ZY, He CY, Ehrhardt A, et al. Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. Mol Ther 2003;8:495-500.
-
(2003)
Mol Ther
, vol.8
, pp. 495-500
-
-
Chen, Z.Y.1
He, C.Y.2
Ehrhardt, A.3
-
23
-
-
78650028269
-
A robust system for production of minicircle DNA vectors
-
Kay MA, He CY, Chen ZY. A robust system for production of minicircle DNA vectors. Nat Biotechnol 2010;28:1287-1289.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1287-1289
-
-
Kay, M.A.1
He, C.Y.2
Chen, Z.Y.3
-
24
-
-
84960976417
-
Minicircle DNA provides enhanced and prolonged transgene expression following airway gene transfer
-
Munye MM, Tagalakis AD, Barnes JL, et al. Minicircle DNA provides enhanced and prolonged transgene expression following airway gene transfer. Sci Rep 2016;6:23125.
-
(2016)
Sci Rep
, vol.6
, pp. 23125
-
-
Munye, M.M.1
Tagalakis, A.D.2
Barnes, J.L.3
-
25
-
-
13844292517
-
Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo
-
Chen ZY, He CY, Kay MA. Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo. Hum Gene Ther 2005;16:126-131.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 126-131
-
-
Chen, Z.Y.1
He, C.Y.2
Kay, M.A.3
-
26
-
-
79954650563
-
State-of - The-art gene-based therapies: The road ahead
-
Kay MA. State-of-the-art gene-based therapies: the road ahead. Nat Rev Genet 2011;12:316-328.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 316-328
-
-
Kay, M.A.1
-
27
-
-
85007206434
-
Treatment of CD20-directed chimeric antigen receptor-modified T cells in patients with relapsed or refractory Bcell non-Hodgkin lymphoma: An early Phase IIa trial report
-
Zhang W-Y, Wang Y, Guo Y-L, et al. Treatment of CD20-directed chimeric antigen receptor-modified T cells in patients with relapsed or refractory Bcell non-Hodgkin lymphoma: an early Phase IIa trial report. Signal Transduct Target Ther 2016; 1:16002.
-
(2016)
Signal Transduct Target Ther
, vol.1
, pp. 16002
-
-
Zhang, W.-Y.1
Wang, Y.2
Guo, Y.-L.3
-
28
-
-
0021832361
-
Hybrid antibodies can target sites for attack by T cells
-
Staerz UD, Kanagawa O, Bevan MJ. Hybrid antibodies can target sites for attack by T cells. Nature 1985;314:628-631.
-
(1985)
Nature
, vol.314
, pp. 628-631
-
-
Staerz, U.D.1
Kanagawa, O.2
Bevan, M.J.3
-
29
-
-
84956580912
-
CD20 antibodyconjugated immunoliposomes for targeted chemotherapy of melanoma cancer initiating cells
-
Song H, Su X, Yang K, et al. CD20 antibodyconjugated immunoliposomes for targeted chemotherapy of melanoma cancer initiating cells. J Biomed Nanotechnol 2015;11:1927-1946.
-
(2015)
J Biomed Nanotechnol
, vol.11
, pp. 1927-1946
-
-
Song, H.1
Su, X.2
Yang, K.3
-
30
-
-
84954236800
-
Prospects for gene-engineered T cell immunotherapy for solid cancers
-
Klebanoff CA, Rosenberg SA, Restifo NP. Prospects for gene-engineered T cell immunotherapy for solid cancers. Nat Med 2016;22:26-36.
-
(2016)
Nat Med
, vol.22
, pp. 26-36
-
-
Klebanoff, C.A.1
Rosenberg, S.A.2
Restifo, N.P.3
-
31
-
-
84969764539
-
Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
-
Stronen E, Toebes M, Kelderman S, et al. Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. Science 2016;352:1337-1341.
-
(2016)
Science
, vol.352
, pp. 1337-1341
-
-
Stronen, E.1
Toebes, M.2
Kelderman, S.3
-
32
-
-
84949730499
-
Immunogenicity of somatic mutations in human gastrointestinal cancers
-
Tran E, Ahmadzadeh M, Lu YC, et al. Immunogenicity of somatic mutations in human gastrointestinal cancers. Science 2015;350:1387-1390.
-
(2015)
Science
, vol.350
, pp. 1387-1390
-
-
Tran, E.1
Ahmadzadeh, M.2
Lu, Y.C.3
-
33
-
-
84900301377
-
Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer
-
Tran E, Turcotte S, Gros A, et al. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer. Science 2014;344:641-645.
-
(2014)
Science
, vol.344
, pp. 641-645
-
-
Tran, E.1
Turcotte, S.2
Gros, A.3
-
34
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M, et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 2003;302:415-419.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
35
-
-
84960393099
-
Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases
-
Osborn MJ, Webber BR, Knipping F, et al. Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases. Mol Ther 2016;24:570-581.
-
(2016)
Mol Ther
, vol.24
, pp. 570-581
-
-
Osborn, M.J.1
Webber, B.R.2
Knipping, F.3
-
36
-
-
84927102567
-
First-inman phase 1 clinical trial of gene therapy for advanced pancreatic cancer: Safety, biodistribution, and preliminary clinical findings
-
Buscail L, Bournet B, Vernejoul F, et al. First-inman phase 1 clinical trial of gene therapy for advanced pancreatic cancer: safety, biodistribution, and preliminary clinical findings. Mol Ther 2015;23:779-789.
-
(2015)
Mol Ther
, vol.23
, pp. 779-789
-
-
Buscail, L.1
Bournet, B.2
Vernejoul, F.3
|