-
1
-
-
70349638289
-
Tumour-initiating cells: Challenges and opportunities for anticancer drug discovery
-
B. B. Zhou, H. Zhang, M. Damelin, K. G. Geles, J. C. Grindley, and P. B. Dirks, Tumour-initiating cells: Challenges and opportunities for anticancer drug discovery. Nat. Rev. Drug Discov. 8, 806 (2009).
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 806
-
-
Zhou, B.B.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
3
-
-
45549100605
-
Melanoma stem cells: The dark seed of melanoma
-
S. E. Zabierowski and M. Herlyn, Melanoma stem cells: The dark seed of melanoma. J. Clin. Oncol. 26, 2890 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2890
-
-
Zabierowski, S.E.1
Herlyn, M.2
-
4
-
-
27144557960
-
A tumorigenic subpopulation with stem cell properties in melanomas
-
D. Fang, T. K. Nguyen, K. Leishear, R. Finko, A. N. Kulp, S. Hotz, P. A. Van Belle, X. Xu, D. E. Elder, and M. Herlyn, A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res. 65, 9328 (2005).
-
(2005)
Cancer Res.
, vol.65
, pp. 9328
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
Finko, R.4
Kulp, A.N.5
Hotz, S.6
Van Belle, P.A.7
Xu, X.8
Elder, D.E.9
Herlyn, M.10
-
5
-
-
79952302092
-
Eradication of melanomas by targeted elimination of a minor subset of tumor cells
-
P. Schmidt, C. Kopecky, A. Hombach, P. Zigrino, C. Mauch, and H. Abken, Eradication of melanomas by targeted elimination of a minor subset of tumor cells. Proc. Natl. Acad. Sci. USA 108, 2474 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 2474
-
-
Schmidt, P.1
Kopecky, C.2
Hombach, A.3
Zigrino, P.4
Mauch, C.5
Abken, H.6
-
6
-
-
84860531228
-
Targeting CD20 in melanoma patients at high risk of dis ease recurrence
-
A. Pinc, R. Somasundaram, C. Wagner, M. Hormann, G. Karanikas, A. Jalili, W. Bauer, P. Brunner, K. Grabmeier-Pfistershammer, M. Gschaider, C. Y. Lai, M. Y. Hsu, M. Herlyn, G. Stingl, and S. N. Wagner, Targeting CD20 in melanoma patients at high risk of dis ease recurrence. Mol. Ther. 20, 1056 (2012).
-
(2012)
Mol. Ther.
, vol.20
, pp. 1056
-
-
Pinc, A.1
Somasundaram, R.2
Wagner, C.3
Hormann, M.4
Karanikas, G.5
Jalili, A.6
Bauer, W.7
Brunner, P.8
Grabmeier-Pfistershammer, K.9
Gschaider, M.10
Lai, C.Y.11
Hsu, M.Y.12
Herlyn, M.13
Stingl, G.14
Wagner, S.N.15
-
7
-
-
0035499267
-
Weissman, Stem cells, cancer, and cancer stem cells
-
T. Reya, S. J. Morrison, M. F. Clarke, and I. L. Weissman, Stem cells, cancer, and cancer stem cells. Nature 414, 105 (2001).
-
(2001)
Nature
, vol.414
, pp. 105
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
-
8
-
-
84861409254
-
Anti-CD20 antibody therapy for B-cell lymphomas
-
D. G. Maloney, Anti-CD20 antibody therapy for B-cell lymphomas. N. Engl. J. Med. 366, 2008 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 2008
-
-
Maloney, D.G.1
-
9
-
-
0345337254
-
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program
-
P. McLaughlin, A. J. Grillo-Lopez, B. K. Link, R. Levy, M. S. Czuczman, M. E. Williams, M. R. Heyman, I. Bence-Bruckler, C. A. White, F. Cabanillas, V. Jain, A. D. Ho, J. Lister, K. Wey, D. Shen, and B. K. Dallaire, Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program. J. Clin. Oncol. 16, 2825 (1998).
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 2825
-
-
McLaughlin, P.1
Grillo-Lopez, A.J.2
Link, B.K.3
Levy, R.4
Czuczman, M.S.5
Williams, M.E.6
Heyman, M.R.7
Bence-Bruckler, I.8
White, C.A.9
Cabanillas, F.10
Jain, V.11
Ho, A.D.12
Lister, J.13
Wey, K.14
Shen, D.15
Dallaire, B.K.16
-
10
-
-
0032530342
-
Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: A multicenter phase II study
-
B. Coiffier, C. Haioun, N. Ketterer, A. Engert, H. Tilly, D. Ma, P. Johnson, A. Lister, M. Feuring-Buske, J. A. Radford, R. Capdev-ille, V. Diehl, and F. Reyes, Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: A multicenter phase II study. Blood 92, 1927 (1998).
-
(1998)
Blood
, vol.92
, pp. 1927
-
-
Coiffier, B.1
Haioun, C.2
Ketterer, N.3
Engert, A.4
Tilly, H.5
Ma, D.6
Johnson, P.7
Lister, A.8
Feuring-Buske, M.9
Radford, J.A.10
Capdev-Ille, R.11
Diehl, V.12
Reyes, F.13
-
11
-
-
0345735397
-
Systemic chemotherapy in the treatment of malignant melanoma
-
M. B. Lens and T. G. Eisen, Systemic chemotherapy in the treatment of malignant melanoma. Expert Opin. Pharmacother. 4, 2205 (2003).
-
(2003)
Expert Opin. Pharmacother.
, vol.4
, pp. 2205
-
-
Lens, M.B.1
Eisen, T.G.2
-
12
-
-
79952269662
-
Systemic therapy of non-resectable metastatic melanoma
-
A. Orouji, S. Goerdt, and J. Utikal, Systemic therapy of non-resectable metastatic melanoma. Cancers (Basel) 2, 955 (2010).
-
(2010)
Cancers (Basel)
, vol.2
, pp. 955
-
-
Orouji, A.1
Goerdt, S.2
Utikal, J.3
-
13
-
-
14144250911
-
Recent advances with liposomes as pharmaceutical carriers
-
V. P. Torchilin, Recent advances with liposomes as pharmaceutical carriers. Nat. Rev. Drug Discov. 4, 145 (2005).
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 145
-
-
Torchilin, V.P.1
-
14
-
-
84957058183
-
Pharmacokinetics (PK) study of sphingosomal vincristine (SV) in patients with metastatic melanoma (MM)
-
New Orleans, LA, USA
-
A. Bedikian, A. Vardeleon, and T. Smith, Pharmacokinetics (PK) study of sphingosomal vincristine (SV) in patients with metastatic melanoma (MM), ASCO Annual Meeting Proceedings, New Orleans, LA, USA (2004), p. 2038.
-
(2004)
ASCO Annual Meeting Proceedings
, pp. 2038
-
-
Bedikian, A.1
Vardeleon, A.2
Smith, T.3
-
15
-
-
56849097154
-
A pilot study with vincristine sulfate liposome infusion in patients with metastatic melanoma
-
A. Y. Bedikian, N. E. Papadopoulos, K. B. Kim, A. Vardeleon, T. Smith, S. B. Lu, and R. Deitcher, A pilot study with vincristine sulfate liposome infusion in patients with metastatic melanoma. Melanoma. Res. 18, 400 (2008).
-
(2008)
Melanoma. Res.
, vol.18
, pp. 400
-
-
Bedikian, A.Y.1
Papadopoulos, N.E.2
Kim, K.B.3
Vardeleon, A.4
Smith, T.5
Lu, S.B.6
Deitcher, R.7
-
16
-
-
80052536727
-
Isolation and characterization of tumor stem-like cells from human meningiomas
-
D. Y. Hueng, H. K. Sytwu, S. M. Huang, C. Chang, and H. I. Ma, Isolation and characterization of tumor stem-like cells from human meningiomas. J. Neurooncol. 104, 45 (2011).
-
(2011)
J. Neurooncol.
, vol.104
, pp. 45
-
-
Hueng, D.Y.1
Sytwu, H.K.2
Huang, S.M.3
Chang, C.4
Ma, H.I.5
-
17
-
-
79951944060
-
Antibody derivatization and conjugation strategies: Application in preparation of stealth immunoliposome to target chemotherapeutics to tumor
-
A. S. Manjappa, K. R. Chaudhari, M. P. Venkataraju, P. Dantuluri, B. Nanda, C. Sidda, K. K. Sawant, and R. S. Murthy, Antibody derivatization and conjugation strategies: Application in preparation of stealth immunoliposome to target chemotherapeutics to tumor. J. Control. Release 150, 2 (2011).
-
(2011)
J. Control. Release
, vol.150
, pp. 2
-
-
Manjappa, A.S.1
Chaudhari, K.R.2
Venkataraju, M.P.3
Dantuluri, P.4
Nanda, B.5
Sidda, C.6
Sawant, K.K.7
Murthy, R.S.8
-
18
-
-
11144354599
-
Phase i and pharmacokinetic study of MCC-465, a doxorubicin (DXR) encapsulated in PEG immunoliposome, in patients with metastatic stomach cancer
-
Y. Matsumura, M. Gotoh, K. Muro, Y. Yamada, K. Shirao, Y. Shimada, M. Okuwa, S. Matsumoto, Y. Miyata, H. Ohkura, K. Chin, S. Baba, T. Yamao, A. Kannami, Y. Takamatsu, K. Ito, and K. Takahashi, Phase I and pharmacokinetic study of MCC-465, a doxorubicin (DXR) encapsulated in PEG immunoliposome, in patients with metastatic stomach cancer. Ann. Oncol. 15, 517 (2004).
-
(2004)
Ann. Oncol.
, vol.15
, pp. 517
-
-
Matsumura, Y.1
Gotoh, M.2
Muro, K.3
Yamada, Y.4
Shirao, K.5
Shimada, Y.6
Okuwa, M.7
Matsumoto, S.8
Miyata, Y.9
Ohkura, H.10
Chin, K.11
Baba, S.12
Yamao, T.13
Kannami, A.14
Takamatsu, Y.15
Ito, K.16
Takahashi, K.17
-
19
-
-
84870243896
-
Tolerability, safety, pharmacokinetics, and efficacy of doxorubicin-loaded anti-EGFR immunoliposomes in advanced solid tumours: A phase 1 dose-escalation study
-
C. Mamot, R. Ritschard, A. Wicki, G. Stehle, T. Dieterle, L. Bubendorf, C. Hilker, S. Deuster, R. Herrmann, and C. Rochlitz, Tolerability, safety, pharmacokinetics, and efficacy of doxorubicin-loaded anti-EGFR immunoliposomes in advanced solid tumours: A phase 1 dose-escalation study. Lancet Oncol. 13, 1234 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, pp. 1234
-
-
Mamot, C.1
Ritschard, R.2
Wicki, A.3
Stehle, G.4
Dieterle, T.5
Bubendorf, L.6
Hilker, C.7
Deuster, S.8
Herrmann, R.9
Rochlitz, C.10
-
20
-
-
24644437854
-
Ligand-targeted liposomes for cancer treatment
-
P. Sapra, P. Tyagi, and T. M. Allen, Ligand-targeted liposomes for cancer treatment. Curr. Drug Deliv. 2, 369 (2005).
-
(2005)
Curr. Drug Deliv.
, vol.2
, pp. 369
-
-
Sapra, P.1
Tyagi, P.2
Allen, T.M.3
-
21
-
-
1842478453
-
Improved outcome when B-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the CD19 and CD20 epitopes
-
P. Sapra and T. M. Allen, Improved outcome when B-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the CD19 and CD20 epitopes. Clin. Cancer Res. 10, 2530 (2004).
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 2530
-
-
Sapra, P.1
Allen, T.M.2
-
22
-
-
2442551191
-
Drug release rate influences the pharmacokinetics, biodistribution, therapeutic activity, and toxicity of pegylated liposomal doxorubicin formulations in murine breast cancer
-
G. J. Charrois and T. M. Allen, Drug release rate influences the pharmacokinetics, biodistribution, therapeutic activity, and toxicity of pegylated liposomal doxorubicin formulations in murine breast cancer. Biochim. Biophys Acta 1663, 167 (2004).
-
(2004)
Biochim. Biophys Acta
, vol.1663
, pp. 167
-
-
Charrois, G.J.1
Allen, T.M.2
-
23
-
-
49249091689
-
Is tumor growth sustained by rare cancer stem cells or dominant clones?
-
J. M. Adams and A. Strasser, Is tumor growth sustained by rare cancer stem cells or dominant clones? Cancer Res. 68, 4018 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 4018
-
-
Adams, J.M.1
Strasser, A.2
-
24
-
-
78751702579
-
Photothermolysis of glioblastoma stem-like cells targeted by carbon nanotubes conjugated with CD133 monoclonal antibody
-
C. H. Wang, S. H. Chiou, C. P. Chou, Y. C. Chen, Y. J. Huang, and C. A. Peng, Photothermolysis of glioblastoma stem-like cells targeted by carbon nanotubes conjugated with CD133 monoclonal antibody. Nanomedicine (Lond.) 7, 69 (2011).
-
(2011)
Nanomedicine (Lond.)
, vol.7
, pp. 69
-
-
Wang, C.H.1
Chiou, S.H.2
Chou, C.P.3
Chen, Y.C.4
Huang, Y.J.5
Peng, C.A.6
-
25
-
-
84865604935
-
Targeting cancer cells: Controlling the binding and internalization of antibody-functionalized capsules
-
A. P. Johnston, M. M. Kamphuis, G. K. Such, A. M. Scott, E. C. Nice, J. K. Heath, and F. Caruso, Targeting cancer cells: Controlling the binding and internalization of antibody-functionalized capsules. ACS. Nano. 6, 6667 (2012).
-
(2012)
ACS. Nano.
, vol.6
, pp. 6667
-
-
Johnston, A.P.1
Kamphuis, M.M.2
Such, G.K.3
Scott, A.M.4
Nice, E.C.5
Heath, J.K.6
Caruso, F.7
-
26
-
-
84885371767
-
Inhibition of hepatocel-lular carcinoma growth using immunoliposomes for co-delivery of adriamycin and ribonucleotide reductase M2 siRNA
-
J. Gao, H. Chen, Y. Yu, J. Song, H. Song, X. Su, W. Li, X. Tong, W. Qian, H. Wang, J. Dai, and Y. Guo, Inhibition of hepatocel-lular carcinoma growth using immunoliposomes for co-delivery of adriamycin and ribonucleotide reductase M2 siRNA. Biomaterials 34, 10084 (2013).
-
(2013)
Biomaterials
, vol.34
, pp. 10084
-
-
Gao, J.1
Chen, H.2
Yu, Y.3
Song, J.4
Song, H.5
Su, X.6
Li, W.7
Tong, X.8
Qian, W.9
Wang, H.10
Dai, J.11
Guo, Y.12
-
27
-
-
84896700482
-
Polymer-lipid hybrid nanoparticles conjugated with anti-EGF receptor antibody for targeted drug delivery to hepa-tocellular carcinoma
-
J. Gao, Y. Xia, H. Chen, Y. Yu, J. Song, W. Li, W. Qian, H. Wang, J. Dai, and Y. Guo, Polymer-lipid hybrid nanoparticles conjugated with anti-EGF receptor antibody for targeted drug delivery to hepa-tocellular carcinoma. Nanomedicine (Lond.) 9, 279 (2014).
-
(2014)
Nanomedicine (Lond.)
, vol.9
, pp. 279
-
-
Gao, J.1
Xia, Y.2
Chen, H.3
Yu, Y.4
Song, J.5
Li, W.6
Qian, W.7
Wang, H.8
Dai, J.9
Guo, Y.10
-
28
-
-
82855165061
-
EGFR-specific PEGylated immuno-liposomes for active siRNA delivery in hepatocellular carcinoma
-
J. Gao, Y. Yu, Y. Zhang, J. Song, H. Chen, W. Li, W. Qian, L. Deng, G. Kou, J. Chen, and Y. Guo, EGFR-specific PEGylated immuno-liposomes for active siRNA delivery in hepatocellular carcinoma. Biomaterials 33, 270 (2012).
-
(2012)
Biomaterials
, vol.33
, pp. 270
-
-
Gao, J.1
Yu, Y.2
Zhang, Y.3
Song, J.4
Chen, H.5
Li, W.6
Qian, W.7
Deng, L.8
Kou, G.9
Chen, J.10
Guo, Y.11
-
29
-
-
0043115126
-
-
Oxford University Press, New York, NY, USA
-
V. P. Torchilin and V. Weissig, Liposomes: A Practical Approach, 2nd edn., Oxford University Press, New York, NY, USA (2003).
-
(2003)
Liposomes: A Practical Approach, 2nd Edn
-
-
Torchilin, V.P.1
Weissig, V.2
-
30
-
-
0028306031
-
Liposomal vincristine which exhibits increased drug retention and increased circulation longevity cures mice bearing P388 tumors
-
N. L. Boman, D. Masin, L. D. Mayer, P. R. Cullis, and M. B. Bally, Liposomal vincristine which exhibits increased drug retention and increased circulation longevity cures mice bearing P388 tumors. Cancer Res. 54, 2830 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 2830
-
-
Boman, N.L.1
Masin, D.2
Mayer, L.D.3
Cullis, P.R.4
Bally, M.B.5
-
31
-
-
0019304939
-
Colorimetric determination of phospholipids with ammonium ferrothiocyanate
-
J. C. Stewart, Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal. Biochem. 104, 10 (1980).
-
(1980)
Anal. Biochem.
, vol.104
, pp. 10
-
-
Stewart, J.C.1
-
32
-
-
0642312825
-
Rituximab (monoclonal anti-CD20 antibody): Mechanisms of action and resistance
-
M. R. Smith, Rituximab (monoclonal anti-CD20 antibody): Mechanisms of action and resistance. Oncogene 22, 7359 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 7359
-
-
Smith, M.R.1
-
33
-
-
0037115543
-
Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs
-
P. Sapra and T. M. Allen, Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs. Cancer Res. 62, 7190 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 7190
-
-
Sapra, P.1
Allen, T.M.2
-
34
-
-
0242523974
-
Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity
-
K. L. Mealey, N. C. Northrup, and S. A. Bentjen, Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity. J. Am. Vet. Med. Assoc. 223, 1453 (2003).
-
(2003)
J. Am. Vet. Med. Assoc.
, vol.223
, pp. 1453
-
-
Mealey, K.L.1
Northrup, N.C.2
Bentjen, S.A.3
-
35
-
-
84859458294
-
Nanomedicine against multidrug resistance in cancer treatment
-
J. Gao, S. S. Feng, and Y. Guo, Nanomedicine against multidrug resistance in cancer treatment. Nanomedicine (Lond.) 7, 465 (2012).
-
(2012)
Nanomedicine (Lond.)
, vol.7
, pp. 465
-
-
Gao, J.1
Feng, S.S.2
Guo, Y.3
-
36
-
-
84862517728
-
Cancer stem cells: Current status and evolving complexities
-
J. E. Visvader and G. J. Lindeman, Cancer stem cells: Current status and evolving complexities. Cell Stem Cell 10, 717 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 717
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
37
-
-
84879983245
-
Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
-
C. L. Chaffer, N. D. Marjanovic, T. Lee, G. Bell, C. G. Kleer, F. Reinhardt, A. C. D'Alessio, R. A. Young, and R. A. Weinberg, Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 154, 61 (2013).
-
(2013)
Cell
, vol.154
, pp. 61
-
-
Chaffer, C.L.1
Marjanovic, N.D.2
Lee, T.3
Bell, G.4
Kleer, C.G.5
Reinhardt, F.6
D'Alessio, A.C.7
Young, R.A.8
Weinberg, R.A.9
-
38
-
-
78649932947
-
Pulsed ultrasound enhances nanoparticle penetration into breast cancer spheroids
-
S. J. Grainger, J. V. Serna, S. Sunny, Y. Zhou, C. X. Deng, and M. E. El-Sayed, Pulsed ultrasound enhances nanoparticle penetration into breast cancer spheroids. Mol. Pharm. 7, 2006 (2010).
-
(2010)
Mol. Pharm.
, vol.7
, pp. 2006
-
-
Grainger, S.J.1
Serna, J.V.2
Sunny, S.3
Zhou, Y.4
Deng, C.X.5
El-Sayed, M.E.6
-
39
-
-
77952901022
-
Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
-
K. N. Sugahara, T. Teesalu, P. P. Karmali, V. R. Kotamraju, L. Agemy, D. R. Greenwald, and E. Ruoslahti, Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs. Science 328, 1031 (2010).
-
(2010)
Science
, vol.328
, pp. 1031
-
-
Sugahara, K.N.1
Teesalu, T.2
Karmali, P.P.3
Kotamraju, V.R.4
Agemy, L.5
Greenwald, D.R.6
Ruoslahti, E.7
-
40
-
-
84896737349
-
Nanomedicine for treatment of cancer stem cells
-
J. Gao, S. S. Feng, and Y. Guo, Nanomedicine for treatment of cancer stem cells. Nanomedicine (Lond.) 9, 181 (2014).
-
(2014)
Nanomedicine (Lond.)
, vol.9
, pp. 181
-
-
Gao, J.1
Feng, S.S.2
Guo, Y.3
-
41
-
-
84862682458
-
Safety assessment of nanomaterials: Implications for nanomedicine
-
A. M. Nystrom and B. Fadeel, Safety assessment of nanomaterials: Implications for nanomedicine. J. Control. Release 161, 403 (2012).
-
(2012)
J. Control. Release
, vol.161
, pp. 403
-
-
Nystrom, A.M.1
Fadeel, B.2
|