Immunogenicity of somatic mutations in human gastrointestinal cancers

Science

Volumn 350, Issue 6266, 2015, Pages 1387-1390

  Tran, Eric ^a   Ahmadzadeh, Mojgan ^a   Lu, Yong Chen ^a   Gros, Alena ^a   Turcotte, Simon ^a,b   Robbins, Paul F ^a   Gartner, Jared J ^a   Zheng, Zhili ^a   Li, Yong F ^a   Ray, Satyajit ^a   Wunderlich, John R ^a   Somerville, Robert P ^a   Rosenberg, Steven A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Institut du Cancer de Montreal   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD137 ANTIGEN; EPITOPE; GAMMA INTERFERON; HLA C ANTIGEN; T LYMPHOCYTE RECEPTOR; HLA-C*08 ANTIGEN; KRAS PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOPROTEIN; RAS PROTEIN;

ANTIGEN; CANCER; IMMUNE RESPONSE; IMMUNE SYSTEM; MUTATION; TUMOR;

ARTICLE; CANCER PATIENT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CYTOKINE RELEASE; DIGESTIVE SYSTEM CANCER; ENZYME LINKED IMMUNOSPOT ASSAY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; IMMUNOGENICITY; LYMPHOCYTIC INFILTRATION; NEXT GENERATION SEQUENCING; PRIORITY JOURNAL; SOMATIC MUTATION; T LYMPHOCYTE ACTIVATION; TUMOR ASSOCIATED LEUKOCYTE; ADULT; FEMALE; GASTROINTESTINAL NEOPLASMS; GENETICS; IMMUNOLOGY; IMMUNOTHERAPY; MALE; MIDDLE AGED; MUTATION; PERSONALIZED MEDICINE; PROCEDURES; TUMOR CELL LINE;

ADULT; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; FEMALE; GASTROINTESTINAL NEOPLASMS; HLA-C ANTIGENS; HUMANS; IMMUNODOMINANT EPITOPES; IMMUNOTHERAPY; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED; MUTATION; PRECISION MEDICINE; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RECEPTORS, ANTIGEN, T-CELL;

EID: 84949730499     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad1253     Document Type: Article

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