Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types

Cancer Discovery

Volumn 6, Issue 9, 2016, Pages 1052-1067

  Kar, Siddhartha P ^a   Beesley, Jonathan ^b   Al Olama, Ali Amin ^a,dn   Michailidou, Kyriaki ^a   Tyrer, Jonathan ^a   Kote Jarai, Z Sofia ^dn   Lawrenson, Kate ^d   Lindstrom, Sara ^e   Ramus, Susan J ^d   Thompson, Deborah J ^a   Kibel, Adam S ^f,dn   Dansonka Mieszkowska, Agnieszka ^g   Michael, Agnieszka ^h,dn   Dieffenbach, Aida K ^i,dn   Gentry Maharaj, Aleksandra ^j   Whittemore, Alice S ^k   Wolk, Alicja ^l   Monteiro, Alvaro ^m   Peixoto, Ana ⁿ   Kierzek, Andrzej ^h,dn   Cox, Angela ^o   Rudolph, Anja ⁱ   Gonzalez Neira, Anna ^p   Wu, Anna H ^d   Lindblom, Annika ^l   Swerdlow, Anthony ^c   Ziogas, Argyrios ^q   Ekici, Arif B ^r   Burwinkel, Barbara ⁱ   Karlan, Beth Y ^s   Nordestgaard, Børge G ^dn   Blomqvist, Carl ^u   Phelan, Catherine ^m   McLean, Catriona ^v   Pearce, Celeste Leigh ^w   Vachon, Celine ^x   Cybulski, Cezary ^y,dn   Slavov, Chavdar ^z,dn   Stegmaier, Christa ^aa   Maier, Christiane ^ab,dn   Ambrosone, Christine B ^ac   Hogdall, Claus K ^ad   Teerlink, Craig C ^ae   Kang, Daehee ^af,ag   Tessier, Daniel C ^ah   Schaid, Daniel J ^x,dn   Stram, Daniel O ^d   Cramer, Daniel W ^f   Neal, David E ^a,ai,dn   Eccles, Diana ^aj   Flesch Janys, Dieter ^ak   Velez Edwards, Digna R ^al   Wokozorczyk, Dominika ^y,dn   Levine, Douglas A ^am   Yannoukakos, Drakoulis ^an   Sawyer, Elinor J ^ao   Bandera, Elisa V ^ap   Poole, Elizabeth M ^e,f   Goode, Ellen L ^x   Khusnutdinova, Elza ^aq,ar   Hogdall, Estrid ^ad,as   Song, Fengju ^at   Bruinsma, Fiona ^au   Heitz, Florian ^av,aw   Modugno, Francesmary ^ax,ay,az   Hamdy, Freddie C ^ba,bb,dn   Wiklund, Fredrik ^l,dn   Giles, Graham G ^au,bc,bd,dn   Olsson, Hakan ^be   Wildiers, Hans ^bf   Ulmer, Hans Ulrich ^bg   Pandha, Hardev ^h,dn   Risch, Harvey A ^bh   Darabi, Hatef ^l   Salvesen, Helga B ^bi,bj   Nevanlinna, Heli ^u   Gronberg, Henrik ^l,dn   Brenner, Hermann ^i,dn   Brauch, Hiltrud ^i,bk,bl   Anton Culver, Hoda ^q   Song, Honglin ^a   Lim, Hui Yi ^m,dn   McNeish, Iain ^bm   Campbell, Ian ^bn,bo   Vergote, Ignace ^bf   Gronwald, Jacek ^y   Lubiński, Jan ^y   Stanford, Janet L ^bp,bq,dn   Benitez, Javier ^p   Doherty, Jennifer A ^br   Permuth, Jennifer B ^m   Chang Claude, Jenny ⁱ   Donovan, Jenny L ^bs,dn   Dennis, Joe ^a   Schildkraut, Joellen M ^bt,bu   Schleutker, Johanna ^bv,bw,dn   Hopper, John L ^bc   Kupryjanczyk, Jolanta ^g   Park, Jong Y ^m,dn   Figueroa, Jonine ^bx   Clements, Judith A ^by   Knight, Julia A ^bz,ca   Peto, Julian ^cb   Cunningham, Julie M ^x   Pow Sang, Julio ^m   Batra, Jyotsna ^by,dn   Czene, Kamila ^l   Lu, Karen H ^cc   Herkommer, Kathleen ^cd,dn   Khaw, Kay Tee ^a,dn   Matsuo, Keitaro ^ce   Muir, Kenneth ^cf,cg,dn   Offitt, Kenneth ^am   Chen, Kexin ^at   Moysich, Kirsten B ^ac   Aittomaki, Kristiina ^u   Odunsi, Kunle ^ac   Kiemeney, Lambertus A ^ch   Massuger, Leon F A G ^ch   Fitzgerald, Liesel M ^au,dn   Cook, Linda S ^ci   Cannon Albright, Lisa ^cj,dn   Hooning, Maartje J ^ck   Pike, Malcolm C ^am   Bolla, Manjeet K ^a   Luedeke, Manuel ^ab,dn   Teixeira, Manuel R ^n,cl,dn   Goodman, Marc T ^s   Schmidt, Marjanka K ^cm   Riggan, Marjorie ^bt   Aly, Markus ^l,cn,dn   Rossing, Mary Anne ^bp,bq   Beckmann, Matthias W ^r   Moisse, Matthieu ^co   Sanderson, Maureen ^cp   Southey, Melissa C ^bo,dn   Jones, Michael ^c   Lush, Michael ^a   Hildebrandt, Michelle A T ^cc   Hou, Ming Feng ^cq   Schoemaker, Minouk J ^c   Garcia Closas, Montserrat ^c,bx   Bogdanova, Natalia ^cr   Rahman, Nazneen ^c   Le, Nhu D ^cs   Orr, Nick ^c   Wentzensen, Nicolas ^bx   Pashayan, Nora ^a,j,dn   Peterlongo, Paolo ^ct   Guenel, Pascal ^cu,cv   Brennan, Paul ^cw   Paulo, Paula ^n,dn   Webb, Penelope M ^b   Broberg, Per ^be   Fasching, Peter A ^r   Devilee, Peter ^cx   Wang, Qin ^a   Cai, Qiuyin ^al   Li, Qiyuan ^cy,cz   Kaneva, Radka ^da,dn   Butzow, Ralf ^u   Kopperud, Reidun Kristin ^bi,bj   Schmutzler, Rita K ^db,dc   Stephenson, Robert A ^ae   Macinnis, Robert J ^au,bc   Hoover, Robert N ^bx   Winqvist, Robert ^dd   Ness, Roberta ^de   Milne, Roger L ^au,bc   Travis, Ruth C ^ba,dn   Benlloch, Sara ^a,dn   Olson, Sara H ^am   McDonnell, Shannon K ^x,dn   Tworoger, Shelley S ^e,f   Maia, Sofia ^n,dn   Berndt, Sonja ^bx   Lee, Soo Chin ^df,dg   Teo, Soo Hwang ^dh,di   Thibodeau, Stephen N ^x,dn   Bojesen, Stig E ^t,dj   Gapstur, Susan M ^dk   Kjar, Susanne Kruger ^ad,as   Pejovic, Tanja ^dl   Tammela, Teuvo L J ^dm,dn   Dork, Thilo ^cr   Bruning, Thomas ^do   Wahlfors, Tiina ^bv,dn   Key, Tim J ^ba,dn   Edwards, Todd L ^al   Menon, Usha ^j   Hamann, Ute ^bg   Mitev, Vanio ^da,dn   Kosma, Veli Matti ^dp,dq   Setiawan, Veronica Wendy ^d   Kristensen, Vessela ^dr,ds,dt   Arndt, Volker ^i,dn   Vogel, Walther ^ab,dn   Zheng, Wei ^al   Sieh, Weiva ^k   Blot, William J ^du   Kluzniak, Wojciech ^y,dn   Shu, Xiao Ou ^al   Gao, Yu Tang ^dv   Schumacher, Fredrick ^d,dn   Freedman, Matthew L ^cy,dw   Berchuck, Andrew ^bt   Dunning, Alison M ^a   Simard, Jacques ^dx   Haiman, Christopher A ^d,dn   Spurdle, Amanda ^b,dn   Sellers, Thomas ^dn   Hunter, David J ^e   Henderson, Brian E ^d,dn   Kraft, Peter ^e   Chanock, Stephen J ^bx   Hall, Per ^l   Gayther, Simon A ^d   Easton, Douglas ^dn   Chenevix Trench, Georgia ^b   Eeles, Rosalind ^c,dy   Pharoah, Paul ^dn   Lambrechts, Diether ^co   more..

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g INSTITUTE OF ONCOLOGY   (Poland)

^h UNIVERSITY OF SURREY   (United Kingdom)

ⁱ GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^j UNIVERSITY COLLEGE LONDON   (United Kingdom)

^k STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l KAROLINSKA INSTITUTE   (Sweden)

^m H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

ⁿ PORTUGUESE ONCOLOGY INSTITUTE   (Portugal)

^o UNIVERSITY OF SHEFFIELD   (United Kingdom)

^p Centro Nacional de Investigaciones Oncológicas   (Spain)

^q UNIVERSITY OF CALIFORNIA   (United States)

^r UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^s CEDARS SINAI MEDICAL CENTER   (United States)

^t GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^u HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^v ALFRED HOSPITAL   (Australia)

^w UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

^x MAYO CLINIC   (United States)

^y POMERANIAN MEDICAL UNIVERSITY   (Poland)

^z UNIVERSITY HOSPITAL ALEXANDROVSKA   (Bulgaria)

^aa SAARLAND CANCER REGISTRY   (Germany)

^ab UNIVERSITY HOSPITAL ULM   (Germany)

^ac ROSWELL PARK CANCER INSTITUTE   (United States)

^ad UNIVERSITY OF COPENHAGEN   (Denmark)

^ae UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^af Seoul National University   (South Korea)

^ag Seoul National University College of Medicine   (South Korea)

^ah MCGILL UNIVERSITY   (Canada)

^ai CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^aj UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^ak UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^al VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^am MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^an INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^ao GUY S HOSPITAL   (United Kingdom)

^ap RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^aq Birsk Branch of Federal State Budgetary Educational Establishment of Higher Education Bashkir State University   (Russian Federation)

^ar INSTITUTE OF BIOCHEMISTRY AND GENETICS   (Russian Federation)

^as DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^at TIANJIN MEDICAL UNIVERSITY   (China)

^au CANCER EPIDEMIOLOGY CENTRE   (Australia)

^av KLINIKEN ESSEN MITTE   (Germany)

^aw DR HORST SCHMIDT KLINIKEN   (Germany)

^ax UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^ay UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^az UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^ba UNIVERSITY OF OXFORD   (United Kingdom)

^bb UNIVERSITY OF OXFORD   (United Kingdom)

^bc UNIVERSITY OF MELBOURNE   (Australia)

^bd MONASH UNIVERSITY   (Australia)

^be LUND UNIVERSITY HOSPITAL   (Sweden)

^bf UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^bg Frauenklinik der Stadtklinik Baden Baden   (Germany)

^bh YALE UNIVERSITY   (United States)

^bi HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^bj UNIVERSITY OF BERGEN   (Norway)

^bk DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^bl UNIVERSITY OF TÜBINGEN   (Germany)

^bm UNIVERSITY OF GLASGOW   (United Kingdom)

^bn PETER MACCALLUM CANCER CENTRE   (Australia)

^bo UNIVERSITY OF MELBOURNE   (Australia)

^bp Fred Hutchinson Cancer Research Center   (United States)

^bq UNIVERSITY OF WASHINGTON   (United States)

^br DARTMOUTH MEDICAL SCHOOL   (United States)

^bs UNIVERSITY OF BRISTOL   (United Kingdom)

^bt DUKE UNIVERSITY MEDICAL CENTER   (United States)

^bu DUKE CANCER INSTITUTE   (United States)

^bv UNIVERSITY OF TURKU   (Finland)

^bw TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^bx NATIONAL CANCER INSTITUTE   (United States)

^by QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^bz MOUNT SINAI HOSPITAL   (Canada)

^ca UNIVERSITY OF TORONTO   (Canada)

^cb LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^cc UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^cd TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^ce KYUSHU UNIVERSITY   (Japan)

^cf UNIVERSITY OF MANCHESTER   (United Kingdom)

^cg UNIVERSITY OF WARWICK   (United Kingdom)

^ch RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^ci UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^cj VETERANS AFFAIRS MEDICAL CENTER   (United States)

^ck ERASMUS MC CANCER INSTITUTE   (Netherlands)

^cl UNIVERSITY OF PORTO   (Portugal)

^cm ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^cn DANDERYD HOSPITAL   (Sweden)

^co UNIVERSITY OF LEUVEN   (Belgium)

^cp MEHARRY MEDICAL COLLEGE   (United States)

^cq KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^cr HANNOVER MEDICAL SCHOOL   (Germany)

^cs BRITISH COLUMBIA CANCER AGENCY   (Canada)

^ct FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^cu CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^cv UNIVERSITÉ PARIS SACLAY   (France)

^cw INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^cx LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^cy DANA FARBER CANCER INSTITUTE   (United States)

^cz XIAMEN UNIVERSITY   (China)

^da MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^db UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^dc UNIVERSITY OF COLOGNE   (Germany)

^dd UNIVERSITY OF OULU   (Finland)

^de UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^df NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

^dg NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^dh CANCER RESEARCH INITIATIVES FOUNDATION   (Malaysia)

^di UNIVERSITY MALAYA MEDICAL CENTRE   (Malaysia)

^dj UNIVERSITY OF COPENHAGEN   (Denmark)

^dk AMERICAN CANCER SOCIETY   (United States)

^dl OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^dm TAMPERE UNIVERSITY HOSPITAL   (Finland)

^dn Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome (PRACTICAL)   (United States)

^do RUHR UNIVERSITY BOCHUM   (Germany)

^dp UNIVERSITY OF EASTERN FINLAND   (Finland)

^dq KUOPIO UNIVERSITY HOSPITAL   (Finland)

^dr OSLO UNIVERSITY HOSPITAL   (Norway)

^ds UNIVERSITY OF OSLO   (Norway)

^dt OSLO UNIVERSITY HOSPITAL   (Norway)

^du VANDERBILT INGRAM CANCER CENTER   (United States)

^dv SHANGHAI CANCER INSTITUTE   (China)

^dw BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^dx LAVAL UNIVERSITY   (Canada)

^dy INSTITUTE OF CANCER RESEARCH   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER RISK; CANCER SUSCEPTIBILITY; ENHANCER REGION; GENE EXPRESSION; GENE INTERACTION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMAN; META ANALYSIS; OVARY CANCER; PROSTATE CANCER; SECOND CANCER; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR GENE; ANTIBODY SPECIFICITY; BREAST TUMOR; CASE CONTROL STUDY; CHROMOSOMAL MAPPING; FEMALE; GENE REGULATORY NETWORK; GENETIC PREDISPOSITION; GENETICS; INFORMATION PROCESSING; MALE; META ANALYSIS (TOPIC); METABOLISM; OVARY TUMOR; PROSTATE TUMOR; QUANTITATIVE TRAIT LOCUS; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CASE-CONTROL STUDIES; CHROMOSOME MAPPING; DATASETS AS TOPIC; ENHANCER ELEMENTS, GENETIC; FEMALE; GENE REGULATORY NETWORKS; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; META-ANALYSIS AS TOPIC; ORGAN SPECIFICITY; OVARIAN NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS; QUANTITATIVE TRAIT LOCI; SIGNAL TRANSDUCTION;

EID: 85012028638     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-15-1227     Document Type: Article

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