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Volumn 90, Issue 5, 2012, Pages 821-835

A subset-based approach improves power and interpretation for the combined analysis of genetic association studies of heterogeneous traits

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BASAL CELL CARCINOMA; BREAST CANCER; CANCER SUSCEPTIBILITY; CHRONIC LYMPHATIC LEUKEMIA; COLORECTAL CANCER; DYSKERATOSIS CONGENITA; GENETIC ASSOCIATION; GENETIC TRAIT; GERM CELL TUMOR; GLIOBLASTOMA; KIDNEY CANCER; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG FIBROSIS; MELANOMA; NASOPHARYNX CANCER; NONHODGKIN LYMPHOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE CANCER; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84860771128     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2012.03.015     Document Type: Article
Times cited : (199)

References (56)
  • 8
    • 77957568513 scopus 로고    scopus 로고
    • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population
    • EMBRACE GEMO Study Collaborators HEBON kConFab SWE-BRCA MOD SQUAD GENICA
    • A.C. Antoniou, X. Wang, Z.S. Fredericksen, L. McGuffog, R. Tarrell, O.M. Sinilnikova, S. Healey, J. Morrison, C. Kartsonaki, T. Lesnick EMBRACE GEMO Study Collaborators HEBON kConFab SWE-BRCA MOD SQUAD GENICA A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population Nat. Genet. 42 2010 885 892
    • (2010) Nat. Genet. , vol.42 , pp. 885-892
    • Antoniou, A.C.1    Wang, X.2    Fredericksen, Z.S.3    McGuffog, L.4    Tarrell, R.5    Sinilnikova, O.M.6    Healey, S.7    Morrison, J.8    Kartsonaki, C.9    Lesnick, T.10
  • 9
    • 77957571905 scopus 로고    scopus 로고
    • A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
    • Wellcome Trust Case-Control Consortium Australian Cancer Study (Ovarian Cancer) Australian Ovarian Cancer Study Group Ovarian Cancer Association Consortium (OCAC) Ovarian Cancer Association Consortium (OCAC)
    • E.L. Goode, G. Chenevix-Trench, H. Song, S.J. Ramus, M. Notaridou, K. Lawrenson, M. Widschwendter, R.A. Vierkant, M.C. Larson, S.K. Kjaer Wellcome Trust Case-Control Consortium Australian Cancer Study (Ovarian Cancer) Australian Ovarian Cancer Study Group Ovarian Cancer Association Consortium (OCAC) Ovarian Cancer Association Consortium (OCAC) A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 Nat. Genet. 42 2010 874 879
    • (2010) Nat. Genet. , vol.42 , pp. 874-879
    • Goode, E.L.1    Chenevix-Trench, G.2    Song, H.3    Ramus, S.J.4    Notaridou, M.5    Lawrenson, K.6    Widschwendter, M.7    Vierkant, R.A.8    Larson, M.C.9    Kjaer, S.K.10
  • 10
    • 77957549881 scopus 로고    scopus 로고
    • GWAS identifies a common breast cancer risk allele among BRCA1 carriers
    • P. Kraft, and C.A. Haiman GWAS identifies a common breast cancer risk allele among BRCA1 carriers Nat. Genet. 42 2010 819 820
    • (2010) Nat. Genet. , vol.42 , pp. 819-820
    • Kraft, P.1    Haiman, C.A.2
  • 11
    • 0023484789 scopus 로고
    • Quantitative methods in the review of epidemiologic literature
    • S. Greenland Quantitative methods in the review of epidemiologic literature Epidemiol. Rev. 9 1987 1 30
    • (1987) Epidemiol. Rev. , vol.9 , pp. 1-30
    • Greenland, S.1
  • 12
    • 31744435871 scopus 로고    scopus 로고
    • Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
    • DOI 10.1038/ng1706, PII NG1706
    • A.D. Skol, L.J. Scott, G.R. Abecasis, and M. Boehnke Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies Nat. Genet. 38 2006 209 213 (Pubitemid 43177235)
    • (2006) Nature Genetics , vol.38 , Issue.2 , pp. 209-213
    • Skol, A.D.1    Scott, L.J.2    Abecasis, G.R.3    Boehnke, M.4
  • 13
    • 71149120793 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies with overlapping subjects
    • D.Y. Lin, and P.F. Sullivan Meta-analysis of genome-wide association studies with overlapping subjects Am. J. Hum. Genet. 85 2009 862 872
    • (2009) Am. J. Hum. Genet. , vol.85 , pp. 862-872
    • Lin, D.Y.1    Sullivan, P.F.2
  • 14
    • 33947133769 scopus 로고    scopus 로고
    • Maxima of discretely sampled random fields, with an application to 'bubbles'
    • DOI 10.1093/biomet/asm004
    • J.E. Taylor, K.J. Worsley, and F. Gosselin Maxima of discretely sampled random fields, with an application to 'bubbles' Biometrika 94 2007 1 18 (Pubitemid 46410713)
    • (2007) Biometrika , vol.94 , Issue.1 , pp. 1-18
    • Taylor, J.E.1    Worsley, K.J.2    Gosselin, F.3
  • 16
    • 77958596172 scopus 로고    scopus 로고
    • P-value based analysis for shared controls design in genome-wide association studies
    • D.V. Zaykin, and D.O. Kozbur P-value based analysis for shared controls design in genome-wide association studies Genet. Epidemiol. 34 2010 725 738
    • (2010) Genet. Epidemiol. , vol.34 , pp. 725-738
    • Zaykin, D.V.1    Kozbur, D.O.2
  • 17
    • 36248977635 scopus 로고    scopus 로고
    • Improving power in genome-wide association studies: Weights tip the scale
    • DOI 10.1002/gepi.20237
    • K. Roeder, B. Devlin, and L. Wasserman Improving power in genome-wide association studies: Weights tip the scale Genet. Epidemiol. 31 2007 741 747 (Pubitemid 350133973)
    • (2007) Genetic Epidemiology , vol.31 , Issue.7 , pp. 741-747
    • Roeder, K.1    Devlin, B.2    Wasserman, L.3
  • 18
    • 77955169164 scopus 로고    scopus 로고
    • Genome-Wide Significance Levels and Weighted Hypothesis Testing
    • K. Roeder, and L. Wasserman Genome-Wide Significance Levels and Weighted Hypothesis Testing Stat. Sci. 24 2009 398 413
    • (2009) Stat. Sci. , vol.24 , pp. 398-413
    • Roeder, K.1    Wasserman, L.2
  • 28
    • 54049136464 scopus 로고    scopus 로고
    • A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis
    • Pirfenidone Clinical Study Group
    • T. Mushiroda, S. Wattanapokayakit, A. Takahashi, T. Nukiwa, S. Kudoh, T. Ogura, H. Taniguchi, M. Kubo, N. Kamatani, Y. Nakamura Pirfenidone Clinical Study Group A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis J. Med. Genet. 45 2008 654 656
    • (2008) J. Med. Genet. , vol.45 , pp. 654-656
    • Mushiroda, T.1    Wattanapokayakit, S.2    Takahashi, A.3    Nukiwa, T.4    Kudoh, S.5    Ogura, T.6    Taniguchi, H.7    Kubo, M.8    Kamatani, N.9    Nakamura, Y.10
  • 38
    • 79959991704 scopus 로고    scopus 로고
    • Current status of genome-wide association studies in cancer
    • C.C. Chung, and S.J. Chanock Current status of genome-wide association studies in cancer Hum. Genet. 130 2011 59 78
    • (2011) Hum. Genet. , vol.130 , pp. 59-78
    • Chung, C.C.1    Chanock, S.J.2
  • 40
    • 33646074053 scopus 로고    scopus 로고
    • Use of phenotypic covariates in association analysis by sequential addition of cases
    • S. Macgregor, N. Craddock, and P.A. Holmans Use of phenotypic covariates in association analysis by sequential addition of cases Eur. J. Hum. Genet. 14 2006 529 534
    • (2006) Eur. J. Hum. Genet. , vol.14 , pp. 529-534
    • MacGregor, S.1    Craddock, N.2    Holmans, P.A.3
  • 41
    • 37149035176 scopus 로고    scopus 로고
    • Increased efficiency of case-control association analysis by using allele-sharing and covariate information
    • DOI 10.1159/000109732
    • S. Schmidt, M.A. Schmidt, X. Qin, E.R. Martin, and E.R. Hauser Increased efficiency of case-control association analysis by using allele-sharing and covariate information Hum. Hered. 65 2008 154 165 (Pubitemid 350253955)
    • (2008) Human Heredity , vol.65 , Issue.3 , pp. 154-165
    • Schmidt, S.1    Schmidt, M.A.2    Qin, X.3    Martin, E.R.4    Hauser, E.R.5
  • 43
    • 0031510622 scopus 로고    scopus 로고
    • Abstract tubes, improved inclusion-exclusion identities and inequalities and importance sampling
    • D.Q. Naiman, and H.P. Wynn Abstract tubes, improved inclusion-exclusion identities and inequalities and importance sampling Ann. Stat. 25 1997 1954 1983
    • (1997) Ann. Stat. , vol.25 , pp. 1954-1983
    • Naiman, D.Q.1    Wynn, H.P.2
  • 44
    • 0034348265 scopus 로고    scopus 로고
    • Numerical evaluation of singular multivariate normal distributions
    • A. Genz, and K.S. Kwong Numerical evaluation of singular multivariate normal distributions J. Stat Comput Simul 68 2000 1 21
    • (2000) J. Stat Comput Simul , vol.68 , pp. 1-21
    • Genz, A.1    Kwong, K.S.2
  • 48
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Nature 447 2007 661 678
    • (2007) Nature , vol.447 , pp. 661-678
  • 49
    • 0034887388 scopus 로고    scopus 로고
    • The significance of not finding a gene
    • DOI 10.1086/323316
    • M.A. Province The significance of not finding a gene Am. J. Hum. Genet. 69 2001 660 663 (Pubitemid 32777705)
    • (2001) American Journal of Human Genetics , vol.69 , Issue.3 , pp. 660-663
    • Province, M.A.1
  • 50
    • 77955151338 scopus 로고    scopus 로고
    • On combining data from genome-wide association studies to discover disease-associated SNPs
    • R.M. Pfeiffer, M.H. Gail, and D. Pee On combining data from genome-wide association studies to discover disease-associated SNPs Stat. Sci. 24 2009 547 560
    • (2009) Stat. Sci. , vol.24 , pp. 547-560
    • Pfeiffer, R.M.1    Gail, M.H.2    Pee, D.3
  • 52
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • B. Han, and E. Eskin Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies Am. J. Hum. Genet. 88 2011 586 598
    • (2011) Am. J. Hum. Genet. , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 54
    • 84860491216 scopus 로고    scopus 로고
    • An adaptively weighted statistic for detecting differential gene expression when combining multiple transcriptomic studies
    • J. Li, and G.C. Tseng An adaptively weighted statistic for detecting differential gene expression when combining multiple transcriptomic studies Ann. Appl. Stat. 5 2011 994 1019
    • (2011) Ann. Appl. Stat. , vol.5 , pp. 994-1019
    • Li, J.1    Tseng, G.C.2
  • 55
    • 79954520229 scopus 로고    scopus 로고
    • PRIMe: A method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies
    • J. Huang, A.D. Johnson, and C.J. O'Donnell PRIMe: A method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies Bioinformatics 27 2011 1201 1206
    • (2011) Bioinformatics , vol.27 , pp. 1201-1206
    • Huang, J.1    Johnson, A.D.2    O'Donnell, C.J.3
  • 56
    • 77954187595 scopus 로고    scopus 로고
    • Analyze multivariate phenotypes in genetic association studies by combining univariate association tests
    • Q. Yang, H. Wu, C.Y. Guo, and C.S. Fox Analyze multivariate phenotypes in genetic association studies by combining univariate association tests Genet. Epidemiol. 34 2010 444 454
    • (2010) Genet. Epidemiol. , vol.34 , pp. 444-454
    • Yang, Q.1    Wu, H.2    Guo, C.Y.3    Fox, C.S.4


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