Inhibition of TRPC6 reduces non-small cell lung cancer cell proliferation and invasion

Oncotarget

Volumn 8, Issue 3, 2017, Pages 5123-5134

  Yang, Li Li ^a,b   Liu, Bing Chen ^a,b   Lu, Xiao Yu ^b   Yan, Yan ^a   Zhai, Yu Jia ^a,b   Bao, Qing ^b   Doetsch, Paul W ^c   Deng, Xingming ^c   Thai, Tiffany L ^b   Alli, Abdel A ^b   Eaton, Douglas C ^b   Shen, Bao Zhong ^a   Ma, He Ping ^b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

Anti cancer drugs; Cell cycle; Confocal microscopy; Intracellular calcium; Metastasis

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; CALCIUM ION; FIBRONECTIN; PROTEIN ZO1; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; 1-(2-(3-(4-METHOXYPHENYL)PROPOXY)-4-METHOXYPHENYLETHYL)-1H-IMIDAZOLE; CALCIUM; IMIDAZOLE DERIVATIVE; TJP1 PROTEIN, HUMAN; TRPC6 PROTEIN, HUMAN;

A-549 CELL LINE; ARTICLE; CELL ADHESION; CELL CYCLE ARREST; CELL CYCLE ASSAY; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; NON SMALL CELL LUNG CANCER; PATCH CLAMP TECHNIQUE; PROTEIN EXPRESSION; WESTERN BLOTTING; CELL CYCLE; CELL MOTION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM; TUMOR INVASION;

A549 CELLS; CALCIUM; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMIDAZOLES; LUNG NEOPLASMS; NEOPLASM INVASIVENESS; RNA, SMALL INTERFERING; TRPC6 CATION CHANNEL; ZONULA OCCLUDENS-1 PROTEIN;

EID: 85011993307     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.14034     Document Type: Article

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