Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor

Nature Communications

Volumn 8, Issue , 2017, Pages

  Wu, Tongde ^a   Huang, Julianne ^a,b   Moore, Patrick J ^a   Little, Michael S ^b   Walton, William G ^b   Fellner, Robert C ^a   Alexis, Neil E ^a   Peter Di, Y ^c   Redinbo, Matthew R ^b   Tilley, Stephen L ^a   Tarran, Robert ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BACTERIAL PERMEABILITY FAMILY MEMBER A1; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; INTERLEUKIN 13; METHACHOLINE; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN PHOSPHATASE; POTASSIUM CHLORIDE; PROTEIN; SALBUTAMOL; SHORT PALATE AND NASAL EPITHELIAL CLONE 1 PROTEIN; UNCLASSIFIED DRUG; BPIFA1 PROTEIN, HUMAN; BPIFA1 PROTEIN, MOUSE; GLYCOPROTEIN; ORAI1 PROTEIN, HUMAN; PHOSPHOPROTEIN; RECOMBINANT PROTEIN; SMALL INTERFERING RNA;

ASTHMA; DISEASE TREATMENT; MUCUS; MUSCLE; PHENOTYPE; PROTEIN; RECOMBINATION; RODENT;

AIRWAY RESISTANCE; AIRWAY SMOOTH MUSCLE CELL; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; ASTHMA; BIOTINYLATION; BRONCHUS EPITHELIUM; CARBOXY TERMINAL SEQUENCE; CELL LYSATE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOPLASM; DENSITOMETRY; DOWN REGULATION; ENDOPLASMIC RETICULUM; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN PHOSPHORYLATION; RESPIRATORY TRACT ALLERGY; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; SPUTUM ANALYSIS; SURFACE BIOTINYLATION; WILD TYPE; ADULT; AGED; ANIMAL; BRONCHUS; CHEMISTRY; CYTOLOGY; EPITHELIUM CELL; FEMALE; GENE KNOCKDOWN; GENETICS; HEK293 CELL LINE; KNOCKOUT MOUSE; METABOLISM; MIDDLE AGED; MOLECULAR DOCKING; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; PHYSIOLOGY; RESPIRATORY MUCOSA; SECRETION (PROCESS); SMOOTH MUSCLE; SPUTUM; YOUNG ADULT;

BACTERIA (MICROORGANISMS); MUS;

ADULT; AGED; ANIMALS; ASTHMA; BRONCHI; EPITHELIAL CELLS; FEMALE; GENE KNOCKDOWN TECHNIQUES; GLYCOPROTEINS; HEK293 CELLS; HUMANS; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; MOLECULAR DOCKING SIMULATION; MUSCLE CONTRACTION; MUSCLE, SMOOTH; ORAI1 PROTEIN; PHOSPHOPROTEINS; RECOMBINANT PROTEINS; RESPIRATORY MUCOSA; RNA, SMALL INTERFERING; SPUTUM; YOUNG ADULT;

EID: 85011932669     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14118     Document Type: Article

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