Deficiency of RAMP1 attenuates antigen-induced airway hyperresponsiveness in mice

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Li, Manyu ^a   Wetzel Strong, Sarah E ^a   Hua, Xiaoyang ^a   Tilley, Stephen L ^a   Oswald, Erin ^b   Krummel, Matthew F ^b   Caron, Kathleen M ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN RECEPTOR LIKE RECEPTOR; RECEPTOR ACTIVITY MODIFYING PROTEIN 1; CALCITONIN GENE RELATED PEPTIDE; RAMP1 PROTEIN, MOUSE;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DISEASE ACTIVITY; FEMALE; IMMUNOCOMPETENT CELL; MALE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PNEUMONIA; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RESPIRATORY TRACT ALLERGY; SIGNAL TRANSDUCTION; ANIMAL; ASTHMA; DISEASE MODEL; GENETICS; HUMAN; INFLAMMATION; LUNG; METABOLISM; PATHOLOGY; SMOOTH MUSCLE FIBER;

ANIMALS; ASTHMA; CALCITONIN GENE-RELATED PEPTIDE; CALCITONIN RECEPTOR-LIKE PROTEIN; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATION; LUNG; MICE; MYOCYTES, SMOOTH MUSCLE; RECEPTOR ACTIVITY-MODIFYING PROTEIN 1; SIGNAL TRANSDUCTION;

EID: 84904260572     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102356     Document Type: Article

References (35)

1. Akinbami LJ, Moorman JE, Liu X (2011) Asthma prevalence, health care use, and mortality: United States, 2005-2009. National health statistics reports: 1-14.
2. Barnett SB, Nurmagambetov TA (2011) Costs of asthma in the United States: 2002-2007. The Journal of allergy and clinical immunology 127: 145-152.
3. Custovic A, Simpson BM, Simpson A, Hallam C, Craven M, et al. (2000) Manchester Asthma and Allergy Study: low-allergen environment can be achieved and maintained during pregnancy and in early life. The Journal of allergy and clinical immunology 105: 252-258. (Pubitemid 30109037)
4. Weidinger S, Gieger C, Rodriguez E, Baurecht H, Mempel M, et al. (2008) Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. PLoS genetics 4: e1000166.
5. Potaczek DP, Michel S, Sharma V, Zeilinger S, Vogelberg C, et al. (2013) Different FCER1A polymorphisms influence IgE levels in asthmatics and non-asthmatics. Pediatric allergy and immunology: official publication of the European Society of Pediatric Allergy and Immunology 24: 441-449.
6. Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, et al. (2013) Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. The Journal of allergy and clinical immunology 132: 313-320 e315.
7. McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, et al. (1998) RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393: 333-339. (Pubitemid 28269699)
8. Fraser NJ, Wise A, Brown J, McLatchie LM, Main MJ, et al. (1999) The amino terminus of receptor activity modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor. Mol Pharmacol 55: 1054-1059. (Pubitemid 29252372)
9. Dackor R, Fritz-Six K, Smithies O and Caron K (2007) Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age. J Biol Chem 282: 18094-18099. (Pubitemid 47100252)
10. Dackor RT, Fritz-Six K, Dunworth WP, Gibbons CL, Smithies O, et al. (2006) Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Mol Cell Biol 26: 2511-2518.
11. Fritz-Six KL, Dunworth WP, Li M and Caron KM (2008) Adrenomedullin signaling is necessary for murine lymphatic vascular development. J Clin Invest 118: 40-50.
12. Caron KM and Smithies O (2001) Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proc Natl Acad Sci U S A 98: 615-619. (Pubitemid 32105091)
13. Salvatore CA, Hershey JC, Corcoran HA, Fay JF, Johnston VK, et al. (2008) Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)- 2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo [4,5-b] pyridin-1-yl)piperidine-1-carbox amide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine. J Pharmacol Exp Ther 324: 416-421. (Pubitemid 351185864)
14. Rosenfeld MG, Mermod JJ, Amara SG, Swanson LW, Sawchenko PE, et al. (1983) Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature 304: 129-135. (Pubitemid 13079138)
15. Brain SD, Williams TJ, Tippins JR, Morris HR and MacIntyre I (1985) Calcitonin gene-related peptide is a potent vasodilator. Nature 313: 54-56. (Pubitemid 15192304)
16. Tang Y, Feng Y and Wang X (1998) Calcitonin gene-related peptide potentiates LPS-induced IL-6 release from mouse peritoneal macrophages. Journal of neuroimmunology 84: 207-212. (Pubitemid 28248407)
17. Aoki-Nagase T, Nagase T, Oh-Hashi Y, Shindo T, Kurihara Y, et al. (2002) Attenuation of antigen-induced airway hyperresponsiveness in CGRP-deficient mice. Am J Physiol Lung Cell Mol Physiol 283: L963-970. (Pubitemid 35204888)
18. Dakhama A, Kanehiro A, Makela MJ, Loader JE, Larsen GL, et al. (2002) Regulation of airway hyperresponsiveness by calcitonin gene-related peptide in allergen sensitized and challenged mice. American journal of respiratory and critical care medicine 165: 1137-1144. (Pubitemid 34415824)
19. Holtwick R, Gotthardt M, Skryabin B, Steinmetz M, Potthast R, et al. (2002) Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure. Proc Natl Acad Sci U S A 99: 7142-7147. (Pubitemid 34526269)
20. Krege JH, Hodgin JB, Hagaman JR and Smithies O (1995) A noninvasive computerized tail-cuff system for measuring blood pressure in mice. Hypertension 25: 1111-1115.
21. Wetzel-Strong SE, Li M, Klein KR, Nishikimi T and Caron KM (2014) Epicardial-derived adrenomedullin drives cardiac hyperplasia during embryogenesis. Developmental dynamics: an official publication of the American Association of Anatomists 243: 243-256.
22. Tilley SL, Jaradat M, Stapleton C, Dixon D, Hua X, et al. (2007) Retinoid-related orphan receptor gamma controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen. J Immunol 178: 3208-3218. (Pubitemid 46333203)
23. Stapleton CM, Jaradat M, Dixon D, Kang HS, Kim SC, et al. (2005) Enhanced susceptibility of staggerer (RORalphasg/sg) mice to lipopolysaccharide-induced lung inflammation. Am J Physiol Lung Cell Mol Physiol 289: L144-152. (Pubitemid 40863564)
24. Bonner K, Kariyawasam HH, Ali FR, Clark P and Kay AB (2010) Expression of functional receptor activity modifying protein 1 by airway epithelial cells with dysregulation in asthma. The Journal of allergy and clinical immunology 126: 1277-1283 e1273.
25. Simms J, Hay DL, Bailey RJ, Konycheva G, Bailey G, et al. (2009) Structure-function analysis of RAMP1 by alanine mutagenesis. Biochemistry 48: 198-205.
26. Tsujikawa K, Yayama K, Hayashi T, Matsushita H, Yamaguchi T, et al. (2007) Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice. Proc Natl Acad Sci U S A 104: 16702-16707. (Pubitemid 350211080)
27. Spergel JM, Mizoguchi E, Brewer JP, Martin TR, Bhan AK, et al. (1998) Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice. J Clin Invest 101: 1614-1622. (Pubitemid 28198490)
28. Wootten D, Lindmark H, Kadmiel M, Willcockson H, Caron KM, et al. (2013) Receptor activity modifying proteins (RAMPs) interact with the VPAC2 receptor and CRF1 receptors and modulate their function. Br J Pharmacol 168: 822-834.
29. Kay AB, Ali FR, Heaney LG, Benyahia F, Soh CP, et al. (2007) Airway expression of calcitonin gene-related peptide in T-cell peptide-induced late asthmatic reactions in atopics. Allergy 62: 495-503. (Pubitemid 46608366)
30. Bonner K, Pease JE, Corrigan CJ, Clark P and Kay AB (2013) CCL17/thymus and activation-regulated chemokine induces calcitonin gene-related peptide in human airway epithelial cells through CCR4. The Journal of allergy and clinical immunology 132: 942-950 e941-943.
31. Yamamoto H, Nagase T, Shindo T, Teramoto S, Aoki-Nagase T, et al. (2007) Adrenomedullin insufficiency increases allergen-induced airway hyperresponsiveness in mice. J Appl Physiol (1985) 102: 2361-2368.
32. Hsieh CS, Heimberger AB, Gold JS, O'Garra A and Murphy KM (1992) Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci U S A 89: 6065-6069.
33. Dabbagh K, Takeyama K, Lee HM, Ueki IF, Lausier JA, et al. (1999) IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo. J Immunol 162: 6233-6237. (Pubitemid 29314987)
34. Coffman RL, Ohara J, Bond MW, Carty J, Zlotnik A, et al. (1986) B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. J Immunol 136: 4538-4541. (Pubitemid 16090673)
35. Toru H, Ra C, Nonoyama S, Suzuki K, Yata J, et al. (1996) Induction of the high-affinity IgE receptor (Fc epsilon RI) on human mast cells by IL-4. International immunology 8: 1367-1373. (Pubitemid 26293886)