메뉴 건너뛰기




Volumn 95, Issue 4, 2017, Pages 992-999

Peripheral treatment with enoxaparin exacerbates amyloid plaque pathology in Tg2576 mice

Author keywords

Alzheimer's disease; amyloid plaques; amyloid precursor protein transgenic mice; A ; enoxaparin; amyloid

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; ENOXAPARIN; ADAM10 ENDOPEPTIDASE; ADAM10 PROTEIN, MOUSE; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; FIBRINOLYTIC AGENT; MEMBRANE PROTEIN; PROTEIN AGGREGATE; SECRETASE;

EID: 85011928424     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23880     Document Type: Article
Times cited : (7)

References (21)
  • 1
    • 33744760876 scopus 로고    scopus 로고
    • Heparin activates beta-secretase (BACE1) of Alzheimer's disease and increases autocatalysis of the enzyme
    • Beckman M, Holsinger RM, Small DH. 2006. Heparin activates beta-secretase (BACE1) of Alzheimer's disease and increases autocatalysis of the enzyme. Biochemistry 45:6703–6714.
    • (2006) Biochemistry , vol.45 , pp. 6703-6714
    • Beckman, M.1    Holsinger, R.M.2    Small, D.H.3
  • 2
    • 2442483898 scopus 로고    scopus 로고
    • Peripheral treatment with enoxaparin, a low molecular weight heparin, reduces plaques and beta-amyloid accumulation in a mouse model of Alzheimer's disease
    • Bergamaschini L, Rossi E, Storini C, Pizzimenti S, Distaso M, Perego C, De Luigi A, Vergani C, De Simoni MG. 2004. Peripheral treatment with enoxaparin, a low molecular weight heparin, reduces plaques and beta-amyloid accumulation in a mouse model of Alzheimer's disease. J Neurosci 24:4181–4186.
    • (2004) J Neurosci , vol.24 , pp. 4181-4186
    • Bergamaschini, L.1    Rossi, E.2    Storini, C.3    Pizzimenti, S.4    Distaso, M.5    Perego, C.6    De Luigi, A.7    Vergani, C.8    De Simoni, M.G.9
  • 3
  • 4
    • 84867336210 scopus 로고    scopus 로고
    • Size and sulfation are critical for the effect of heparin on APP processing and Abeta production
    • Cui H, Hung AC, Freeman C, Narkowicz C, Jacobson GA, Small DH. 2012. Size and sulfation are critical for the effect of heparin on APP processing and Abeta production. J Neurochem 123:447–457.
    • (2012) J Neurochem , vol.123 , pp. 447-457
    • Cui, H.1    Hung, A.C.2    Freeman, C.3    Narkowicz, C.4    Jacobson, G.A.5    Small, D.H.6
  • 5
    • 0036147384 scopus 로고    scopus 로고
    • Oral and subcutaneous administration of the glycosaminoglycan C3 attenuates Abeta(25–35)-induced abnormal tau protein immunoreactivity in rat brain
    • Dudas B, Cornelli U, Lee JM, Hejna MJ, Walzer M, Lorens SA, Mervis RF, Fareed J, Hanin I. 2002. Oral and subcutaneous administration of the glycosaminoglycan C3 attenuates Abeta(25–35)-induced abnormal tau protein immunoreactivity in rat brain. Neurobiol Aging 23:97–104.
    • (2002) Neurobiol Aging , vol.23 , pp. 97-104
    • Dudas, B.1    Cornelli, U.2    Lee, J.M.3    Hejna, M.J.4    Walzer, M.5    Lorens, S.A.6    Mervis, R.F.7    Fareed, J.8    Hanin, I.9
  • 6
    • 36949016215 scopus 로고    scopus 로고
    • Alzheimer disease models and human neuropathology: similarities and differences
    • Duyckaerts C, Potier MC, Delatour B. 2008. Alzheimer disease models and human neuropathology: similarities and differences. Acta Neuropathol 115:5–38.
    • (2008) Acta Neuropathol , vol.115 , pp. 5-38
    • Duyckaerts, C.1    Potier, M.C.2    Delatour, B.3
  • 7
    • 33847662852 scopus 로고    scopus 로고
    • Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide
    • Haass C, Selkoe DJ. 2007. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 8:101–112.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 101-112
    • Haass, C.1    Selkoe, D.J.2
  • 9
    • 0027425060 scopus 로고
    • The C-terminus of the beta protein is critical in amyloidogenesis
    • Jarrett JT, Berger EP, Lansbury PT Jr. 1993a. The C-terminus of the beta protein is critical in amyloidogenesis. Ann N Y Acad Sci 695:144–148.
    • (1993) Ann N Y Acad Sci , vol.695 , pp. 144-148
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury, P.T.3
  • 10
    • 0027258525 scopus 로고
    • The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease
    • Jarrett JT, Berger EP, Lansbury PT Jr. 1993b. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 32:4693–4697.
    • (1993) Biochemistry , vol.32 , pp. 4693-4697
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury, P.T.3
  • 11
    • 84929000422 scopus 로고    scopus 로고
    • Overexpression of heparanase lowers the amyloid burden in amyloid-beta precursor protein transgenic mice
    • Jendresen CB, Cui H, Zhang X, Vlodavsky I, Nilsson LN, Li JP. 2015. Overexpression of heparanase lowers the amyloid burden in amyloid-beta precursor protein transgenic mice. J Biol Chem 290:5053–5064.
    • (2015) J Biol Chem , vol.290 , pp. 5053-5064
    • Jendresen, C.B.1    Cui, H.2    Zhang, X.3    Vlodavsky, I.4    Nilsson, L.N.5    Li, J.P.6
  • 12
    • 0028913416 scopus 로고
    • Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease
    • Kisilevsky R, Lemieux LJ, Fraser PE, Kong X, Hultin PG, Szarek WA. 1995. Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease. Nat Med 1:143–148.
    • (1995) Nat Med , vol.1 , pp. 143-148
    • Kisilevsky, R.1    Lemieux, L.J.2    Fraser, P.E.3    Kong, X.4    Hultin, P.G.5    Szarek, W.A.6
  • 13
    • 0029665851 scopus 로고    scopus 로고
    • Electrophoretic separation of betaA4 peptides (1–40) and (1–42)
    • Klafki HW, Wiltfang J, Staufenbiel M. 1996. Electrophoretic separation of betaA4 peptides (1–40) and (1–42). Anal Biochem 237:24–29.
    • (1996) Anal Biochem , vol.237 , pp. 24-29
    • Klafki, H.W.1    Wiltfang, J.2    Staufenbiel, M.3
  • 15
    • 0031938180 scopus 로고    scopus 로고
    • Heparin oligosaccharides that pass the blood–brain barrier inhibit beta-amyloid precursor protein secretion and heparin binding to beta-amyloid peptide
    • Leveugle B, Ding W, Laurence F, Dehouck MP, Scanameo A, Cecchelli R, Fillit H. 1998. Heparin oligosaccharides that pass the blood–brain barrier inhibit beta-amyloid precursor protein secretion and heparin binding to beta-amyloid peptide. J Neurochem 70:736–744.
    • (1998) J Neurochem , vol.70 , pp. 736-744
    • Leveugle, B.1    Ding, W.2    Laurence, F.3    Dehouck, M.P.4    Scanameo, A.5    Cecchelli, R.6    Fillit, H.7
  • 17
    • 0033572813 scopus 로고    scopus 로고
    • Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth
    • McLaurin J, Franklin T, Zhang X, Deng J, Fraser PE. 1999. Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth. Eur J Biochem 266:1101–1110.
    • (1999) Eur J Biochem , vol.266 , pp. 1101-1110
    • McLaurin, J.1    Franklin, T.2    Zhang, X.3    Deng, J.4    Fraser, P.E.5
  • 18
    • 0142059961 scopus 로고    scopus 로고
    • Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase
    • Scholefield Z, Yates EA, Wayne G, Amour A, McDowell W, Turnbull JE. 2003. Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase. J Cell Biol 163:97–107.
    • (2003) J Cell Biol , vol.163 , pp. 97-107
    • Scholefield, Z.1    Yates, E.A.2    Wayne, G.3    Amour, A.4    McDowell, W.5    Turnbull, J.E.6
  • 19
    • 0024273721 scopus 로고
    • The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease
    • Snow AD, Mar H, Nochlin D, Kimata K, Kato M, Suzuki S, Hassell J, Wight TN. 1988. The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease. Am J Pathol 133:456–463.
    • (1988) Am J Pathol , vol.133 , pp. 456-463
    • Snow, A.D.1    Mar, H.2    Nochlin, D.3    Kimata, K.4    Kato, M.5    Suzuki, S.6    Hassell, J.7    Wight, T.N.8
  • 20
    • 77955844393 scopus 로고    scopus 로고
    • Enoxaparin treatment administered at both early and late stages of amyloid beta deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain A beta levels
    • Timmer NM, van Dijk L, van der Zee CE, Kiliaan A, de Waal RM, Verbeek MM. 2010. Enoxaparin treatment administered at both early and late stages of amyloid beta deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain A beta levels. Neurobiol Dis 40:340–347.
    • (2010) Neurobiol Dis , vol.40 , pp. 340-347
    • Timmer, N.M.1    van Dijk, L.2    van der Zee, C.E.3    Kiliaan, A.4    de Waal, R.M.5    Verbeek, M.M.6
  • 21
    • 0030858230 scopus 로고    scopus 로고
    • Low-molecular-weight heparins
    • Weitz JI. 1997. Low-molecular-weight heparins. N Engl J Med 337:688–698.
    • (1997) N Engl J Med , vol.337 , pp. 688-698
    • Weitz, J.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.