메뉴 건너뛰기




Volumn 73, Issue 3, 2016, Pages 445-455

Adherence to Mediterranean diet is associated with methylation changes in inflammation-related genes in peripheral blood cells

Author keywords

Adherence; Diet; DNA; Epigenetics; Mediterranean; Methylation

Indexed keywords

C REACTIVE PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; TUMOR NECROSIS FACTOR; INTERCELLULAR ADHESION MOLECULE 1; TNF PROTEIN, HUMAN; TRANSCRIPTOME; VASCULAR CELL ADHESION MOLECULE 1;

EID: 85011807493     PISSN: 11387548     EISSN: 18778755     Source Type: Journal    
DOI: 10.1007/s13105-017-0552-6     Document Type: Article
Times cited : (109)

References (49)
  • 1
    • 80053609375 scopus 로고    scopus 로고
    • Tamoxifen and flaxseed alter angiogenesis regulators in normal breast tissue in vivo
    • PID: 21984941
    • Åberg UW, Saarinen N, Abrahamsson A et al (2011) Tamoxifen and flaxseed alter angiogenesis regulators in normal breast tissue in vivo. PLoS One 6(9):e25720
    • (2011) PLoS One , vol.6 , Issue.9
    • Åberg, U.W.1    Saarinen, N.2    Abrahamsson, A.3
  • 2
    • 34347377877 scopus 로고    scopus 로고
    • Human IL4I1 is a secreted L-phenylalanine oxidase expressed by mature dendritic cells that inhibits T-lymphocyte proliferation
    • COI: 1:CAS:528:DC%2BD2sXnsVaisb8%3D, PID: 17356132
    • Boulland ML, Marquet J, Molinier-Frenkel V et al (2007) Human IL4I1 is a secreted L-phenylalanine oxidase expressed by mature dendritic cells that inhibits T-lymphocyte proliferation. Blood 110(1):220–227
    • (2007) Blood , vol.110 , Issue.1 , pp. 220-227
    • Boulland, M.L.1    Marquet, J.2    Molinier-Frenkel, V.3
  • 3
    • 84865477690 scopus 로고    scopus 로고
    • Epigenetics: are there implications for personalised nutrition?
    • COI: 1:CAS:528:DC%2BC38XhtF2jtrbI, PID: 22878237
    • Burdge GC, Hoile SP, Lillycrop KA (2012) Epigenetics: are there implications for personalised nutrition? Curr Opin Clin Nutr Metab Care 15(5):442–447
    • (2012) Curr Opin Clin Nutr Metab Care , vol.15 , Issue.5 , pp. 442-447
    • Burdge, G.C.1    Hoile, S.P.2    Lillycrop, K.A.3
  • 4
    • 78751694576 scopus 로고    scopus 로고
    • Bridging the gap between epigenetics research and nutritional public health interventions
    • PID: 21067534
    • Burdge GC, Lillycrop KA (2010) Bridging the gap between epigenetics research and nutritional public health interventions. Genome Medicine 2(11):80
    • (2010) Genome Medicine , vol.2 , Issue.11 , pp. 80
    • Burdge, G.C.1    Lillycrop, K.A.2
  • 5
    • 66749093541 scopus 로고    scopus 로고
    • Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition
    • COI: 1:CAS:528:DC%2BD1MXhtlWrtrbE, PID: 19339705
    • Burdge GC, Lillycrop KA, Phillips ES et al (2009) Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition. J Nutr 139(6):1054–1060
    • (2009) J Nutr , vol.139 , Issue.6 , pp. 1054-1060
    • Burdge, G.C.1    Lillycrop, K.A.2    Phillips, E.S.3
  • 6
    • 67650466971 scopus 로고    scopus 로고
    • TNF-α promoter methylation as a predictive biomarker for weight-loss response
    • Campión J, Milagro FI, Goyenechea E et al (2009) TNF-α promoter methylation as a predictive biomarker for weight-loss response. Obesity (Silver Spring) 17(6):1293–1297
    • (2009) Obesity (Silver Spring) , vol.17 , Issue.6 , pp. 1293-1297
    • Campión, J.1    Milagro, F.I.2    Goyenechea, E.3
  • 7
    • 84903384930 scopus 로고    scopus 로고
    • The effects of the mediterranean diet on biomarkers of vascular wall inflammation and plaque vulnerability in subjects with high risk for cardiovascular disease. A randomized trial
    • Casas R, Sacanella E, Urpí-Sardà M et al (2010) The effects of the mediterranean diet on biomarkers of vascular wall inflammation and plaque vulnerability in subjects with high risk for cardiovascular disease. A randomized trial. PLoS One 9(6):e100084
    • (2010) PLoS One , vol.9 , Issue.6
    • Casas, R.1    Sacanella, E.2    Urpí-Sardà, M.3
  • 8
    • 79960990097 scopus 로고    scopus 로고
    • Eicopentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein delta in U937 leukemia cells
    • COI: 1:CAS:528:DC%2BC3MXpsVOntrc%3D, PID: 21659508
    • Ceccarelli V, Racanicchi S, Martelli MP et al (2011) Eicopentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein delta in U937 leukemia cells. J Biol Chem 286(31):27092–27102
    • (2011) J Biol Chem , vol.286 , Issue.31 , pp. 27092-27102
    • Ceccarelli, V.1    Racanicchi, S.2    Martelli, M.P.3
  • 9
    • 69449098702 scopus 로고    scopus 로고
    • Gene expression profile of primary prostate epithelial and stromal cells in response to sulforaphane or iberin exposure
    • COI: 1:CAS:528:DC%2BD1MXhtFOktLrF, PID: 19489030
    • Chambers KF, Bacon JR, Kemsley EK et al (2009) Gene expression profile of primary prostate epithelial and stromal cells in response to sulforaphane or iberin exposure. Prostate 69(13):1411–1421
    • (2009) Prostate , vol.69 , Issue.13 , pp. 1411-1421
    • Chambers, K.F.1    Bacon, J.R.2    Kemsley, E.K.3
  • 10
    • 79960144827 scopus 로고    scopus 로고
    • Epigenetics: a new bridge between nutrition and health
    • COI: 1:CAS:528:DC%2BC3MXpsF2ltbc%3D, PID: 22043447
    • Choi SW, Friso S (2010) Epigenetics: a new bridge between nutrition and health. Adv Nutr 1:8–16
    • (2010) Adv Nutr , vol.1 , pp. 8-16
    • Choi, S.W.1    Friso, S.2
  • 11
    • 84856407154 scopus 로고    scopus 로고
    • Leptin and TNF-alpha promoter methylation levels measured by MSP could predict the response to a low-calorie diet
    • COI: 1:CAS:528:DC%2BC3MXhtVWgt7%2FE, PID: 21465273
    • Cordero P, Campión J, Milagro FI et al (2011) Leptin and TNF-alpha promoter methylation levels measured by MSP could predict the response to a low-calorie diet. J Physiol Biochem 67(3):463–470
    • (2011) J Physiol Biochem , vol.67 , Issue.3 , pp. 463-470
    • Cordero, P.1    Campión, J.2    Milagro, F.I.3
  • 12
    • 85032512882 scopus 로고    scopus 로고
    • Effect of the Mediterranean diet on DNA methylation of selected genes in the PREDIMED-Valencia Intervention Trial
    • Corella D, Ordovás JM, Sorlí JV et al. (2015) Effect of the Mediterranean diet on DNA methylation of selected genes in the PREDIMED-Valencia Intervention Trial. The FASEB Journal 29(1): Suppl LB242
    • (2015) The FASEB Journal 29(1): Suppl LB242
    • Corella, D.1    Ordovás, J.M.2    Sorlí, J.V.3
  • 13
    • 85026487800 scopus 로고    scopus 로고
    • Diabetes and aging are associated with lower methylation levels of the irisin (FNDC5) gene, whereas higher adherence to the Mediterranean diet and physical activity increased methylation of these CpG sites in the PREDIMED-Valencia Study
    • Corella D, Ortega-Azorín C, Coltell O et al (2016) Diabetes and aging are associated with lower methylation levels of the irisin (FNDC5) gene, whereas higher adherence to the Mediterranean diet and physical activity increased methylation of these CpG sites in the PREDIMED-Valencia Study. Obesity Facts 9(Suppl 1):121
    • (2016) Obesity Facts , vol.9 , pp. 121
    • Corella, D.1    Ortega-Azorín, C.2    Coltell, O.3
  • 14
    • 84893743280 scopus 로고    scopus 로고
    • DNA methylation pattern in overweight women under an energy-restricted diet supplemented with fish oil
    • PID: 24579084
    • Do Amaral CL, Milagro FI, Curi R et al (2014) DNA methylation pattern in overweight women under an energy-restricted diet supplemented with fish oil. Biomed Res Int 2014:675021
    • (2014) Biomed Res Int , vol.2014 , pp. 675021
    • Do Amaral, C.L.1    Milagro, F.I.2    Curi, R.3
  • 15
    • 33745475669 scopus 로고    scopus 로고
    • Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial
    • PID: 16818923
    • Estruch R, Martínez-González MA, Corella D et al (2006) Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Intern Med 145(1):1–11
    • (2006) Ann Intern Med , vol.145 , Issue.1 , pp. 1-11
    • Estruch, R.1    Martínez-González, M.A.2    Corella, D.3
  • 16
    • 84875787136 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with a Mediterranean diet
    • COI: 1:CAS:528:DC%2BC3sXls1akt7c%3D, PID: 23432189
    • Estruch R, Ros E, Salas-Salvadó J et al (2013) Primary prevention of cardiovascular disease with a Mediterranean diet. NEJM 368(14):1279–1290
    • (2013) NEJM , vol.368 , Issue.14 , pp. 1279-1290
    • Estruch, R.1    Ros, E.2    Salas-Salvadó, J.3
  • 17
    • 84977079547 scopus 로고    scopus 로고
    • Guide and position of the International Society of Nutrigenetics/Nutrigenomics on personalized nutrition: part 1—fields of precision nutrition
    • PID: 27169401
    • Ferguson LR, De Caterina R, Görman U et al (2016) Guide and position of the International Society of Nutrigenetics/Nutrigenomics on personalized nutrition: part 1—fields of precision nutrition. J Nutrigenet Nutrigenomics 9:12–27
    • (2016) J Nutrigenet Nutrigenomics , vol.9 , pp. 12-27
    • Ferguson, L.R.1    De Caterina, R.2    Görman, U.3
  • 18
    • 23044514669 scopus 로고    scopus 로고
    • Epigenetic differences arise during the lifetime of monozygotic twins
    • COI: 1:CAS:528:DC%2BD2MXntVSiur0%3D, PID: 16009939
    • Fraga MF, Ballestar E, Paz MF et al (2005) Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A 102(30):10604–10609
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.30 , pp. 10604-10609
    • Fraga, M.F.1    Ballestar, E.2    Paz, M.F.3
  • 19
    • 84963815239 scopus 로고    scopus 로고
    • Future perspectives of personalized weight loss interventions based on nutrigenetic, epigenetic and metagenomic data
    • Goni L, Cuervo M, Milagro FI et al. (2016) Future perspectives of personalized weight loss interventions based on nutrigenetic, epigenetic and metagenomic data. J Nutr
    • (2016) J Nutr
    • Goni, L.1    Cuervo, M.2    Milagro, F.I.3
  • 20
    • 84873810502 scopus 로고    scopus 로고
    • Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis
    • PID: 23202732
    • González-Terán B, Cortés JR, Manieri E et al (2013) Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis. J Clin Invest 123(1):164–178
    • (2013) J Clin Invest , vol.123 , Issue.1 , pp. 164-178
    • González-Terán, B.1    Cortés, J.R.2    Manieri, E.3
  • 21
    • 80053654433 scopus 로고    scopus 로고
    • The CpG island methylation regulated expression of endothelial proangiogenic genes in response to β-carotene and arachidonic acid
    • COI: 1:CAS:528:DC%2BC3MXht1KktrzP, PID: 21864059
    • Kiec-Wilk B, Sliwa A, Mikolajczyk M et al (2011) The CpG island methylation regulated expression of endothelial proangiogenic genes in response to β-carotene and arachidonic acid. Nutr Cancer 63(7):1053–1063
    • (2011) Nutr Cancer , vol.63 , Issue.7 , pp. 1053-1063
    • Kiec-Wilk, B.1    Sliwa, A.2    Mikolajczyk, M.3
  • 22
    • 84975154472 scopus 로고    scopus 로고
    • Guide and position of the International Society of Nutrigenetics/Nutrigenomics on personalized nutrition: part 2 - ethics, challenges and endeavors of precision nutrition
    • PID: 27286972
    • Kohlmeier M, De Caterina R, Ferguson LR et al (2016) Guide and position of the International Society of Nutrigenetics/Nutrigenomics on personalized nutrition: part 2 - ethics, challenges and endeavors of precision nutrition. J Nutrigenet Nutrigenomics 9:28–46
    • (2016) J Nutrigenet Nutrigenomics , vol.9 , pp. 28-46
    • Kohlmeier, M.1    De Caterina, R.2    Ferguson, L.R.3
  • 23
    • 79952531428 scopus 로고    scopus 로고
    • Effects of altered maternal folic acid, vitamin B12 and docosahexaenoic acid on placental global DNA methylation patterns in Wistar rats
    • COI: 1:CAS:528:DC%2BC3MXjslKlsrw%3D, PID: 21423696
    • Kulkarni A, Dangat K, Kale A et al (2011) Effects of altered maternal folic acid, vitamin B12 and docosahexaenoic acid on placental global DNA methylation patterns in Wistar rats. PLoS One 6(3):e17706
    • (2011) PLoS One , vol.6 , Issue.3
    • Kulkarni, A.1    Dangat, K.2    Kale, A.3
  • 24
    • 79960113856 scopus 로고    scopus 로고
    • Epigenetic modifications of metastasis suppressor genes in colon cancer metastasis
    • COI: 1:CAS:528:DC%2BC38Xht1OrsrY%3D, PID: 21758003
    • Li Q, Chen H (2011) Epigenetic modifications of metastasis suppressor genes in colon cancer metastasis. Epigenetics 6(7):849–852
    • (2011) Epigenetics , vol.6 , Issue.7 , pp. 849-852
    • Li, Q.1    Chen, H.2
  • 25
    • 84937848055 scopus 로고    scopus 로고
    • Differential DNA methylation in relation to age and health risks of obesity
    • COI: 1:CAS:528:DC%2BC2MXhslymtbjK, PID: 26213922
    • Mansego ML, Milagro FI, Zulet MA et al (2015) Differential DNA methylation in relation to age and health risks of obesity. Int J Mol Sci 16:16816–16832
    • (2015) Int J Mol Sci , vol.16 , pp. 16816-16832
    • Mansego, M.L.1    Milagro, F.I.2    Zulet, M.A.3
  • 26
    • 84859630947 scopus 로고    scopus 로고
    • Cohort profile: design and methods of the PREDIMED study
    • PID: 21172932
    • Martínez-González MA, Corella D, Salas-Salvadó J et al (2012) Cohort profile: design and methods of the PREDIMED study. Int J Epidemiol 41(2):377–385
    • (2012) Int J Epidemiol , vol.41 , Issue.2 , pp. 377-385
    • Martínez-González, M.A.1    Corella, D.2    Salas-Salvadó, J.3
  • 27
    • 84936938968 scopus 로고    scopus 로고
    • Benefits of the Mediterranean diet: insights from the PREDIMED study
    • PID: 25940230
    • Martínez-González MA, Salas-Salvadó J, Estruch R et al (2015) Benefits of the Mediterranean diet: insights from the PREDIMED study. Prog Cardiovasc Dis 58(1):50–60
    • (2015) Prog Cardiovasc Dis , vol.58 , Issue.1 , pp. 50-60
    • Martínez-González, M.A.1    Salas-Salvadó, J.2    Estruch, R.3
  • 29
    • 67249155691 scopus 로고    scopus 로고
    • High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats
    • COI: 1:CAS:528:DC%2BD1MXnvVyjsL4%3D, PID: 19588726
    • Milagro FI, Campión J, García-Díaz DF et al (2009) High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats. J Physiol Biochem 65(1):1–10
    • (2009) J Physiol Biochem , vol.65 , Issue.1 , pp. 1-10
    • Milagro, F.I.1    Campión, J.2    García-Díaz, D.F.3
  • 30
    • 84878106876 scopus 로고    scopus 로고
    • Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives
    • COI: 1:CAS:528:DC%2BC3sXnvVGqt7g%3D
    • Milagro FI, Mansego ML, De Miguel C et al (2013) Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives. Mol Asp Med 34(4):782–812
    • (2013) Mol Asp Med , vol.34 , Issue.4 , pp. 782-812
    • Milagro, F.I.1    Mansego, M.L.2    De Miguel, C.3
  • 31
    • 84875262038 scopus 로고    scopus 로고
    • The Mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled trial
    • COI: 1:CAS:528:DC%2BC38XhtlOntrbN, PID: 22999065
    • Mitjavila MT, Fandos M, Salas-Salvadó J et al (2013) The Mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled trial. Clin Nutr 32(2):172–178
    • (2013) Clin Nutr , vol.32 , Issue.2 , pp. 172-178
    • Mitjavila, M.T.1    Fandos, M.2    Salas-Salvadó, J.3
  • 32
    • 84954290016 scopus 로고    scopus 로고
    • Cell-autonomous brown-like adipogenesis of preadipocytes from retinoblastoma haploinsufficient mice
    • Petro PD, Palou A, Bonet ML et al (2016) Cell-autonomous brown-like adipogenesis of preadipocytes from retinoblastoma haploinsufficient mice. J Cell Physiol 231(9):1941–1952
    • (2016) J Cell Physiol , vol.231 , Issue.9 , pp. 1941-1952
    • Petro, P.D.1    Palou, A.2    Bonet, M.L.3
  • 33
    • 84929649679 scopus 로고    scopus 로고
    • Leptin receptor signaling in T cells is required for Th17 differentiation
    • COI: 1:CAS:528:DC%2BC2MXotl2nsLo%3D, PID: 25917102
    • Reis BS, Lee K, Fanok MH et al (2015) Leptin receptor signaling in T cells is required for Th17 differentiation. J Immunol 194(11):5253–5260
    • (2015) J Immunol , vol.194 , Issue.11 , pp. 5253-5260
    • Reis, B.S.1    Lee, K.2    Fanok, M.H.3
  • 34
    • 84966536744 scopus 로고    scopus 로고
    • RStudio, Inc., Boston, MA: Available
    • RStudio Team (2015) RStudio: integrated development for R. RStudio, Inc., Boston, MA Available: http://www.rstudio.com/
    • (2015) RStudio: integrated development for R
  • 35
    • 43449103667 scopus 로고    scopus 로고
    • Components of the Mediterranean-type food pattern and serum inflammatory markers among patients at high risk for cardiovascular disease
    • PID: 17440519
    • Salas-Salvadó J, Garcia-Arellano A, Estruch R et al (2008) Components of the Mediterranean-type food pattern and serum inflammatory markers among patients at high risk for cardiovascular disease. Eur J Clin Nutr 62(5):651–659
    • (2008) Eur J Clin Nutr , vol.62 , Issue.5 , pp. 651-659
    • Salas-Salvadó, J.1    Garcia-Arellano, A.2    Estruch, R.3
  • 36
    • 75549090082 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase-activated protein kinase 2 in the p38/TNF-alpha pathway of systemic and cutaneous inflammation
    • COI: 1:CAS:528:DC%2BC3cXntVamuw%3D%3D, PID: 19657354
    • Schottelius AJ, Zügel U, Döcke WD et al (2010) The role of mitogen-activated protein kinase-activated protein kinase 2 in the p38/TNF-alpha pathway of systemic and cutaneous inflammation. J Invest Dermatol 130(2):481–491
    • (2010) J Invest Dermatol , vol.130 , Issue.2 , pp. 481-491
    • Schottelius, A.J.1    Zügel, U.2    Döcke, W.D.3
  • 37
    • 79958192773 scopus 로고    scopus 로고
    • A short screener is valid for assessing Mediterranean diet adherence among older Spanish men and women
    • COI: 1:CAS:528:DC%2BC3MXmvFehtLk%3D, PID: 21508208
    • Schroder H, Fito M, Estruch R et al (2011) A short screener is valid for assessing Mediterranean diet adherence among older Spanish men and women. J Nutr 141:1140–1145
    • (2011) J Nutr , vol.141 , pp. 1140-1145
    • Schroder, H.1    Fito, M.2    Estruch, R.3
  • 38
    • 74049141478 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • COI: 1:CAS:528:DC%2BC3cXktlCntw%3D%3D, PID: 19752007
    • Sharma S, Kelly TK, Jones PA (2010) Epigenetics in cancer. Carcinogenesis 31(1):27–36
    • (2010) Carcinogenesis , vol.31 , Issue.1 , pp. 27-36
    • Sharma, S.1    Kelly, T.K.2    Jones, P.A.3
  • 39
    • 84945206699 scopus 로고    scopus 로고
    • Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis
    • COI: 1:CAS:528:DC%2BC2MXhs1CqsbzE, PID: 26366945
    • Sun Z, Cunningham J, Slager S et al (2015) Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis. Epigenomics 7(5):813–828
    • (2015) Epigenomics , vol.7 , Issue.5 , pp. 813-828
    • Sun, Z.1    Cunningham, J.2    Slager, S.3
  • 40
    • 84878107240 scopus 로고    scopus 로고
    • Epigenetics: the link between nature and nurture
    • COI: 1:CAS:528:DC%2BC3sXnvVGkt78%3D
    • Tammen SA, Friso S, Choi SW (2013) Epigenetics: the link between nature and nurture. Mol Asp Med 34(4):753–764
    • (2013) Mol Asp Med , vol.34 , Issue.4 , pp. 753-764
    • Tammen, S.A.1    Friso, S.2    Choi, S.W.3
  • 41
    • 84862266444 scopus 로고    scopus 로고
    • Complete pipeline for Infinium® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation
    • COI: 1:CAS:528:DC%2BC38XosVahs7s%3D, PID: 22690668
    • Touleimat N, Tost J (2012) Complete pipeline for Infinium® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation. Epigenomics 4(3):325–341
    • (2012) Epigenomics , vol.4 , Issue.3 , pp. 325-341
    • Touleimat, N.1    Tost, J.2
  • 42
    • 84890840256 scopus 로고    scopus 로고
    • Genetic variation in the peroxisome proliferator-activated receptor (PPAR) and peroxisome proliferator-activated receptor gamma co-activator 1 (PGC1) gene families and type 2 diabetes
    • COI: 1:CAS:528:DC%2BC2cXhtVOhtbk%3D, PID: 24359475
    • Villegas R, Williams SM, Gao YT et al (2014) Genetic variation in the peroxisome proliferator-activated receptor (PPAR) and peroxisome proliferator-activated receptor gamma co-activator 1 (PGC1) gene families and type 2 diabetes. Ann Hum Genet 78(1):23–32
    • (2014) Ann Hum Genet , vol.78 , Issue.1 , pp. 23-32
    • Villegas, R.1    Williams, S.M.2    Gao, Y.T.3
  • 43
    • 84858800629 scopus 로고    scopus 로고
    • DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
    • COI: 1:CAS:528:DC%2BC38XhtVKisLg%3D, PID: 22293752
    • Volkmar M, Dedeurwaerder S, Cunha DA et al (2012) DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients. EMBO J 31(6):1405–1426
    • (2012) EMBO J , vol.31 , Issue.6 , pp. 1405-1426
    • Volkmar, M.1    Dedeurwaerder, S.2    Cunha, D.A.3
  • 44
    • 27144549048 scopus 로고    scopus 로고
    • Targeted intestinal overexpression of the immediate early gene tis7 in transgenic mice increases triglyceride absorption and adiposity
    • COI: 1:CAS:528:DC%2BD2MXhtVyksrbI, PID: 16085642
    • Wang Y, Iordanov H, Swietlicki EA et al (2005) Targeted intestinal overexpression of the immediate early gene tis7 in transgenic mice increases triglyceride absorption and adiposity. J Biol Chem 280(41):34764–34775
    • (2005) J Biol Chem , vol.280 , Issue.41 , pp. 34764-34775
    • Wang, Y.1    Iordanov, H.2    Swietlicki, E.A.3
  • 45
    • 0029033135 scopus 로고
    • Mediterranean diet pyramid: a cultural model for healthy eating
    • COI: 1:STN:280:DyaK2M3nsVKhsg%3D%3D, PID: 7754995
    • Willett WC, Sacks F, Trichopoulou A et al (1995) Mediterranean diet pyramid: a cultural model for healthy eating. Am J Clin Nutr 61(6 Suppl):1402S–1406S
    • (1995) Am J Clin Nutr , vol.61 , pp. 1402S-1406S
    • Willett, W.C.1    Sacks, F.2    Trichopoulou, A.3
  • 46
    • 84907997839 scopus 로고    scopus 로고
    • Gene body methylation can alter gene expression and is a therapeutic target in cancer
    • COI: 1:CAS:528:DC%2BC2cXhs1agt77F, PID: 25263941
    • Yang X, Han H, De Carvalho DD et al (2014) Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell 26:577–590
    • (2014) Cancer Cell , vol.26 , pp. 577-590
    • Yang, X.1    Han, H.2    De Carvalho, D.D.3
  • 47
    • 34047207526 scopus 로고    scopus 로고
    • Fucoxanthin, a natural carotenoid, induces G1 arrest and GADD45 gene expression in human cancer cells
    • COI: 1:CAS:528:DC%2BD2sXkslyltL0%3D, PID: 17436581
    • Yoshiko S, Hoyoku N (2007) Fucoxanthin, a natural carotenoid, induces G1 arrest and GADD45 gene expression in human cancer cells. In vivo 21(2):305–309
    • (2007) In vivo , vol.21 , Issue.2 , pp. 305-309
    • Yoshiko, S.1    Hoyoku, N.2
  • 48
    • 84957563216 scopus 로고    scopus 로고
    • IL4I1 is a novel regulator of M2 macrophage polarization that can inhibit T cell activation via L-tryptophan and arginine depletion and IL-10 production
    • PID: 26599209
    • Yue Y, Huang W, Liang J et al (2015) IL4I1 is a novel regulator of M2 macrophage polarization that can inhibit T cell activation via L-tryptophan and arginine depletion and IL-10 production. PLoS One 10(11):e0142979
    • (2015) PLoS One , vol.10 , Issue.11
    • Yue, Y.1    Huang, W.2    Liang, J.3
  • 49
    • 0347709124 scopus 로고    scopus 로고
    • Mechanisms for LEPR-mediated regulation of leptin expression in brown and white adipocytes in rat pups
    • COI: 1:CAS:528:DC%2BD3MXks1yktbs%3D, PID: 11160998
    • Zhang Y, Hufnagel C, Eiden S et al (2001) Mechanisms for LEPR-mediated regulation of leptin expression in brown and white adipocytes in rat pups. Physiol Genomics 4(3):189–199
    • (2001) Physiol Genomics , vol.4 , Issue.3 , pp. 189-199
    • Zhang, Y.1    Hufnagel, C.2    Eiden, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.