Activated platelets induce endothelial cell activation via an interleukin-1β pathway in systemic lupus erythematosus

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 37, Issue 4, 2017, Pages 707-716

  Nhek, Sokha ^a   Clancy, Robert ^a   Lee, Kristen A ^a   Allen, Nicole M ^a   Barrett, Tessa J ^a   Marcantoni, Emanuela ^a   Nwaukoni, Janet ^a   Rasmussen, Sara ^a   Rubin, Maya ^a   Newman, Jonathan D ^a   Buyon, Jill P ^a   Berger, Jeffrey S ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blood platelets; Cardiovascular diseases; Endothelial cells; Interleukin 1; Lupus erythematosus; Platelet aggregation; Systemic

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 8; NEUTRALIZING ANTIBODY; RNA; IL1B PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR;

ADULT; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKOCYTE AGGREGATION; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MONOCYTE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SLEDAI; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; UMBILICAL VEIN ENDOTHELIAL CELL; ANTAGONISTS AND INHIBITORS; BLOOD; BLOOD CLOTTING PARAMETERS; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; PHENOTYPE; SIGNAL TRANSDUCTION; THROMBOCYTE; YOUNG ADULT;

ADULT; ANTIBODIES, NEUTRALIZING; BLOOD PLATELETS; CELLS, CULTURED; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-1BETA; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; PHENOTYPE; PLATELET ACTIVATION; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 85011708052     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.308126     Document Type: Article

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