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Volumn 63, Issue 3, 2013, Pages 280-288

Aspirin attenuates platelet activation and immune activation in HIV-1-infected subjects on antiretroviral therapy: A pilot study

Author keywords

Aggregation; Aspirin; HIV 1; Immune activation; Platelets

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; COLLAGEN; HLA DR ANTIGEN; TOLL LIKE RECEPTOR;

EID: 84880246969     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e31828a292c     Document Type: Article
Times cited : (132)

References (43)
  • 1
    • 84861039112 scopus 로고    scopus 로고
    • HIV-1 infection and coronary heart disease: An intersection of epidemics
    • Triant VA. HIV-1 infection and coronary heart disease: an intersection of epidemics. J Infect Dis. 2012;205(suppl 3):S355-S361.
    • (2012) J Infect Dis. , vol.205 , Issue.SUPPL. 3
    • Triant, V.A.1
  • 2
    • 78049258742 scopus 로고    scopus 로고
    • Predicting the riskofcardiovascular disease in HIV-1-infected patients: The data collection on adverse effects of anti-HIV-1 drugs study
    • Friis-Moller N, Thiebaut R, Reiss P, et al. Predicting the riskofcardiovascular disease in HIV-1-infected patients: the data collection on adverse effects of anti-HIV-1 drugs study. Eur J Cardiovasc Prev Rehabil. 2010;17:491-501.
    • (2010) Eur J Cardiovasc Prev Rehabil. , vol.17 , pp. 491-501
    • Friis-Moller, N.1    Thiebaut, R.2    Reiss, P.3
  • 3
    • 64249114114 scopus 로고    scopus 로고
    • Cardiovascular complications in HIV-1 management: Past, present, and future
    • Aberg JA. Cardiovascular complications in HIV-1 management: past, present, and future. J Acquir Immune Defic Syndr. 2009;50:54-64.
    • (2009) J Acquir Immune Defic Syndr. , vol.50 , pp. 54-64
    • Aberg, J.A.1
  • 4
    • 33751515147 scopus 로고    scopus 로고
    • CD4+ count-guided interruption of antiretroviral treatment
    • El-Sadr WM, Lundgren JD, Neaton JD, et al. CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med. 2006;355:2283-2296.
    • (2006) N Engl J Med. , vol.355 , pp. 2283-2296
    • El-Sadr, W.M.1    Lundgren, J.D.2    Neaton, J.D.3
  • 5
    • 84864469250 scopus 로고    scopus 로고
    • HIV replication and immune status are independent predictors of the risk of myocardial infarction in HIV-infected individuals
    • Lang S, Mary-Krause M, Simon A, et al. HIV replication and immune status are independent predictors of the risk of myocardial infarction in HIV-infected individuals. Clin Infect Dis. 2012;55:600-607.
    • (2012) Clin Infect Dis. , vol.55 , pp. 600-607
    • Lang, S.1    Mary-Krause, M.2    Simon, A.3
  • 6
    • 77955705895 scopus 로고    scopus 로고
    • Low CD4+ T cell count is a risk factor for cardiovascular disease events in the HIV-1 outpatient study
    • Lichtenstein KA, Armon C, Buchacz K, et al. Low CD4+ T cell count is a risk factor for cardiovascular disease events in the HIV-1 outpatient study. Clin Infect Dis. 2010;51:435-447.
    • (2010) Clin Infect Dis. , vol.51 , pp. 435-447
    • Lichtenstein, K.A.1    Armon, C.2    Buchacz, K.3
  • 7
    • 0032955651 scopus 로고    scopus 로고
    • Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage
    • Giorgi JV, Hultin LE, McKeating JA, et al. Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J Infect Dis. 1999;179:859-870.
    • (1999) J Infect Dis. , vol.179 , pp. 859-870
    • Giorgi, J.V.1    Hultin, L.E.2    McKeating, J.A.3
  • 8
    • 0041327667 scopus 로고    scopus 로고
    • Persistent immune activation in HIV-1-1 infection is associated with progression to AIDS
    • Hazenberg MD, Otto SA, van Benthem BH, et al. Persistent immune activation in HIV-1-1 infection is associated with progression to AIDS. AIDS. 2003;17:1881-1888.
    • (2003) AIDS , vol.17 , pp. 1881-1888
    • Hazenberg, M.D.1    Otto, S.A.2    Van Benthem, B.H.3
  • 9
    • 77949377332 scopus 로고    scopus 로고
    • Risk of all-cause mortality associated with nonfatal AIDS and serious non-AIDS events among adults infected with HIV-1
    • Neuhaus J, Angus B, Kowalska JD, et al. Risk of all-cause mortality associated with nonfatal AIDS and serious non-AIDS events among adults infected with HIV-1. AIDS. 2010;24:697-706.
    • (2010) AIDS , vol.24 , pp. 697-706
    • Neuhaus, J.1    Angus, B.2    Kowalska, J.D.3
  • 10
    • 84859753760 scopus 로고    scopus 로고
    • Increased platelet and micropar-ticle activation in HIV-1 infection: Upregulation of P-selectin and tissue factor expression
    • Mayne E, Funderburg NT, Sieg SF, et al. Increased platelet and micropar-ticle activation in HIV-1 infection: upregulation of P-selectin and tissue factor expression. J Acquir Immune Defic Syndr. 2012;59:340-346.
    • (2012) J Acquir Immune Defic Syndr. , vol.59 , pp. 340-346
    • Mayne, E.1    Funderburg, N.T.2    Sieg, S.F.3
  • 11
    • 84859426362 scopus 로고    scopus 로고
    • Detection of circulating platelet-monocyte complexes in persons infected with human immunodeficiency virus type-1
    • Singh MV, Davidson DC, Kiebala M, et al. Detection of circulating platelet-monocyte complexes in persons infected with human immunodeficiency virus type-1. J Virol Methods. 2012;181:170-176.
    • (2012) J Virol Methods. , vol.181 , pp. 170-176
    • Singh, M.V.1    Davidson, D.C.2    Kiebala, M.3
  • 12
    • 78549272749 scopus 로고    scopus 로고
    • Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis
    • Lievens D, Zernecke A, Seijkens T, et al. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood. 2010; 116:4317-4327.
    • (2010) Blood. , vol.116 , pp. 4317-4327
    • Lievens, D.1    Zernecke, A.2    Seijkens, T.3
  • 14
    • 0025280866 scopus 로고
    • Platelet hyperreactivity and prognosis in survivors of myocardial infarction
    • Trip MD, Cats VM, van Capelle FJ, et al. Platelet hyperreactivity and prognosis in survivors of myocardial infarction. N Engl J Med. 1990;322: 1549-1554.
    • (1990) N Engl J Med. , vol.322 , pp. 1549-1554
    • Trip, M.D.1    Cats, V.M.2    Van Capelle, F.J.3
  • 15
    • 77956454663 scopus 로고    scopus 로고
    • Platelet CD154 potentiates inter-feron-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus
    • Duffau P, Seneschal J, Nicco C, et al. Platelet CD154 potentiates inter-feron-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus. Sci Transl Med. 2010;2:47ra63.
    • (2010) Sci Transl Med. , vol.2
    • Duffau, P.1    Seneschal, J.2    Nicco, C.3
  • 16
    • 79958074275 scopus 로고    scopus 로고
    • Platelets and the innate immune system: Mechanisms of bacterial-induced platelet activation
    • Cox D, Kerrigan SW, Watson SP. Platelets and the innate immune system: mechanisms of bacterial-induced platelet activation. J Thromb Hae-most. 2011;9:1097-1107.
    • (2011) J Thromb Hae-most. , vol.9 , pp. 1097-1107
    • Cox, D.1    Kerrigan, S.W.2    Watson, S.P.3
  • 17
    • 0023228517 scopus 로고
    • Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death
    • Tofler GH, Brezinski D, Schafer AI, et al. Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death. N Engl J Med. 1987;316:1514-1518.
    • (1987) N Engl J Med. , vol.316 , pp. 1514-1518
    • Tofler, G.H.1    Brezinski, D.2    Schafer, A.I.3
  • 18
    • 84155189166 scopus 로고    scopus 로고
    • Centrifugation speed affects light transmission aggregometry
    • Merolla M, Nardi MA, Berger JS. Centrifugation speed affects light transmission aggregometry. Int J Lab Hematol. 2012;34:81-85.
    • (2012) Int J Lab Hematol. , vol.34 , pp. 81-85
    • Merolla, M.1    Nardi, M.A.2    Berger, J.S.3
  • 19
    • 0031694872 scopus 로고    scopus 로고
    • Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins
    • Rossio JL, Esser MT, Suryanarayana K, et al. Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins. J Virol. 1998;72:7992-8001.
    • (1998) J Virol. , vol.72 , pp. 7992-8001
    • Rossio, J.L.1    Esser, M.T.2    Suryanarayana, K.3
  • 20
    • 84872241845 scopus 로고    scopus 로고
    • Hyperreactive platelet phenotypes: Relationship to altered serotonin transporter number, transport kinetics and intrinsic response to adrenergic co stimulation
    • Berger JS, Becker RC, Kuhn C, et al. Hyperreactive platelet phenotypes: Relationship to altered serotonin transporter number, transport kinetics and intrinsic response to adrenergic co stimulation. Thromb Haemost. 2013;109:85-92.
    • (2013) Thromb Haemost. , vol.109 , pp. 85-92
    • Berger, J.S.1    Becker, R.C.2    Kuhn, C.3
  • 21
    • 0035969983 scopus 로고    scopus 로고
    • Soluble P-selectin and the risk of future cardiovascular events
    • Ridker PM, Buring JE, Rifai N. Soluble P-selectin and the risk of future cardiovascular events. Circulation. 2001;103:491-495.
    • (2001) Circulation. , vol.103 , pp. 491-495
    • Ridker, P.M.1    Buring, J.E.2    Rifai, N.3
  • 22
    • 84861114268 scopus 로고    scopus 로고
    • T cell subset distribution in HIV-1-1 infected patients after 12 years of treatment induced viraemic suppression
    • Ronsholt FF, Ullum H, Katzenstein TL, et al. T cell subset distribution in HIV-1-1 infected patients after 12 years of treatment induced viraemic suppression. J Acquir Immune Defic Syndr. 2012;61:270-278.
    • (2012) J Acquir Immune Defic Syndr. , vol.61 , pp. 270-278
    • Ronsholt, F.F.1    Ullum, H.2    Katzenstein, T.L.3
  • 23
    • 84856016549 scopus 로고    scopus 로고
    • HIV-1-induced T-cell activation/exhaustion in rectal mucosa is controlled only partially by antire-troviral treatment
    • Rueda CM, Velilla PA, Chougnet CA, et al. HIV-1-induced T-cell activation/exhaustion in rectal mucosa is controlled only partially by antire-troviral treatment. PLoS One. 2012;7:e30307.
    • (2012) PLoS One. , vol.7
    • Rueda, C.M.1    Velilla, P.A.2    Chougnet, C.A.3
  • 24
    • 16244393385 scopus 로고    scopus 로고
    • Aspirin down-regulates tryptophan degradation in stimulated human peripheral blood mono-nuclear cells in vitro
    • Schroecksnadel K, Winkler C, Wirleitner B, et al. Aspirin down-regulates tryptophan degradation in stimulated human peripheral blood mono-nuclear cells in vitro. Clin Exp Immunol. 2005;140:41-45.
    • (2005) Clin Exp Immunol. , vol.140 , pp. 41-45
    • Schroecksnadel, K.1    Winkler, C.2    Wirleitner, B.3
  • 25
    • 0028167846 scopus 로고
    • Inhibition of NF-kappa B by sodium salicylate and aspirin
    • Kopp E, Ghosh S. Inhibition of NF-kappa B by sodium salicylate and aspirin. Science. 1994;265:956-959.
    • (1994) Science. , vol.265 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 26
    • 22244470043 scopus 로고    scopus 로고
    • Type i interferon production is profoundly and transiently impaired in primary HIV-1-1 infection
    • Kamga I, Kahi S, Develioglu L, et al. Type I interferon production is profoundly and transiently impaired in primary HIV-1-1 infection. J Infect Dis. 2005;192:303-310.
    • (2005) J Infect Dis. , vol.192 , pp. 303-310
    • Kamga, I.1    Kahi, S.2    Develioglu, L.3
  • 27
    • 0038142359 scopus 로고    scopus 로고
    • Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1-1
    • Donaghy H, Gazzard B, Gotch F, et al. Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1-1. Blood. 2003;101:4505-4511.
    • (2003) Blood. , vol.101 , pp. 4505-4511
    • Donaghy, H.1    Gazzard, B.2    Gotch, F.3
  • 28
    • 19344378561 scopus 로고    scopus 로고
    • Dendritic cell numbers in the blood of HIV-1-1 infected patients before and after changes in antiretroviral therapy
    • Finke JS, Shodell M, Shah K, et al. Dendritic cell numbers in the blood of HIV-1-1 infected patients before and after changes in antiretroviral therapy. J Clin Immunol. 2004;24:647-652.
    • (2004) J Clin Immunol. , vol.24 , pp. 647-652
    • Finke, J.S.1    Shodell, M.2    Shah, K.3
  • 29
    • 78049314539 scopus 로고    scopus 로고
    • Biomarkers of immune dysfunction in HIV-1
    • Nixon DE, Landay AL. Biomarkers of immune dysfunction in HIV-1. Curr Opin HIV-1 AIDS. 2010;5:498-503.
    • (2010) Curr Opin HIV-1 AIDS. , vol.5 , pp. 498-503
    • Nixon, D.E.1    Landay, A.L.2
  • 30
    • 80355129311 scopus 로고    scopus 로고
    • Association of low level viremia with inflammation and mortality in HIV-1-infected adults
    • Eastburn A, Scherzer R, Zolopa AR, et al. Association of low level viremia with inflammation and mortality in HIV-1-infected adults. PLoS One. 2011; 6:e26320.
    • (2011) PLoS One. , vol.6
    • Eastburn, A.1    Scherzer, R.2    Zolopa, A.R.3
  • 31
    • 79956196632 scopus 로고    scopus 로고
    • Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death
    • Boulware DR, Hullsiek KH, Puronen CE, et al. Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death. J Infect Dis. 2011;203:1637-1646.
    • (2011) J Infect Dis. , vol.203 , pp. 1637-1646
    • Boulware, D.R.1    Hullsiek, K.H.2    Puronen, C.E.3
  • 32
    • 84861128115 scopus 로고    scopus 로고
    • Sudden cardiac death in patients with human immunodeficiency virus infection
    • Tseng ZH, Secemsky EA, Dowdy D, et al. Sudden cardiac death in patients with human immunodeficiency virus infection. J Am Coll Car-diol. 2012;59:1891-1896.
    • (2012) J Am Coll Car-diol. , vol.59 , pp. 1891-1896
    • Tseng, Z.H.1    Secemsky, E.A.2    Dowdy, D.3
  • 33
    • 78650198657 scopus 로고    scopus 로고
    • Association of immunologic and virologic factors with myocardial infarction rates in a US healthcare system
    • Triant VA, Regan S, Lee H, et al. Association of immunologic and virologic factors with myocardial infarction rates in a US healthcare system. J Acquir Immune Defic Syndr. 2010;55:615-619.
    • (2010) J Acquir Immune Defic Syndr. , vol.55 , pp. 615-619
    • Triant, V.A.1    Regan, S.2    Lee, H.3
  • 34
    • 84857046136 scopus 로고    scopus 로고
    • Long-term complications in patients with poor immunological recovery despite virolog-ical successful HAART in Dutch ATHENA cohort
    • van Lelyveld SF, Gras L, Kesselring A, et al. Long-term complications in patients with poor immunological recovery despite virolog-ical successful HAART in Dutch ATHENA cohort. AIDS. 2012;26: 465-474.
    • (2012) AIDS , vol.26 , pp. 465-474
    • Van Lelyveld, S.F.1    Gras, L.2    Kesselring, A.3
  • 35
    • 79751470489 scopus 로고    scopus 로고
    • T cell activation and senescence predict subclinical carotid artery disease in HIV-1-infected women
    • Kaplan RC, Sinclair E, Landay AL, et al. T cell activation and senescence predict subclinical carotid artery disease in HIV-1-infected women. J Infect Dis. 2011;203:452-463.
    • (2011) J Infect Dis. , vol.203 , pp. 452-463
    • Kaplan, R.C.1    Sinclair, E.2    Landay, A.L.3
  • 36
    • 2042459552 scopus 로고    scopus 로고
    • Platelet characteristics associated with coronary artery disease
    • McBane RD II, Karnicki K, Tahirkheli N, et al. Platelet characteristics associated with coronary artery disease. J Thromb Haemost. 2003;1: 1296-1303.
    • (2003) J Thromb Haemost. , vol.1 , pp. 1296-1303
    • McBane II, R.D.1    Karnicki, K.2    Tahirkheli, N.3
  • 37
    • 0018271085 scopus 로고
    • "exhausted" platelets continue to circulate
    • O'Brien JR. "Exhausted" platelets continue to circulate. Lancet. 1978;2: 1316-1317.
    • (1978) Lancet. , vol.2 , pp. 1316-1317
    • O'Brien, J.R.1
  • 38
    • 3042640509 scopus 로고    scopus 로고
    • Expression of Toll-like receptors on human platelets
    • Shiraki R, Inoue N, Kawasaki S, et al. Expression of Toll-like receptors on human platelets. Thromb Res. 2004;113:379-385.
    • (2004) Thromb Res. , vol.113 , pp. 379-385
    • Shiraki, R.1    Inoue, N.2    Kawasaki, S.3
  • 39
    • 33846160633 scopus 로고    scopus 로고
    • In vivo effects of lipo-polysaccharide and TLR4 on platelet production and activity: Implications for thrombotic risk
    • Jayachandran M, Brunn GJ, Karnicki K, et al. In vivo effects of lipo-polysaccharide and TLR4 on platelet production and activity: implications for thrombotic risk. J Appl Physiol. 2007;102:429-433.
    • (2007) J Appl Physiol. , vol.102 , pp. 429-433
    • Jayachandran, M.1    Brunn, G.J.2    Karnicki, K.3
  • 40
    • 33846118743 scopus 로고    scopus 로고
    • Platelets as immune cells: Bridging inflammation and cardiovascular disease
    • von Hundelshausen P, Weber C. Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ Res. 2007;100:27-40.
    • (2007) Circ Res. , vol.100 , pp. 27-40
    • Von Hundelshausen, P.1    Weber, C.2
  • 41
    • 43549095273 scopus 로고    scopus 로고
    • Platelet-derived CD154 enables T-cell priming and protection against Listeria monocytogenes challenge
    • Elzey BD, Schmidt NW, Crist SA, et al. Platelet-derived CD154 enables T-cell priming and protection against Listeria monocytogenes challenge. Blood. 2008;111:3684-3691.
    • (2008) Blood. , vol.111 , pp. 3684-3691
    • Elzey, B.D.1    Schmidt, N.W.2    Crist, S.A.3
  • 42
    • 0028913968 scopus 로고
    • Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation
    • Weyrich AS, McIntyre TM, McEver RP, et al. Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation. J Clin Invest. 1995;95:2297-2303.
    • (1995) J Clin Invest. , vol.95 , pp. 2297-2303
    • Weyrich, A.S.1    McIntyre, T.M.2    McEver, R.P.3
  • 43
    • 33846816545 scopus 로고    scopus 로고
    • Immunomodulatory effect of nonsteroidal anti-inflammatory drugs (NSAIDs) at the clinically available doses
    • Cho JY. Immunomodulatory effect of nonsteroidal anti-inflammatory drugs (NSAIDs) at the clinically available doses. Arch Pharm Res. 2007;30:64-74. Science Allergy and Infectious Diseases
    • (2007) Arch Pharm Res. , vol.30 , pp. 64-74
    • Cho, J.Y.1


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