Signal transducer and activator of transcription 3 (STAT3) regulates collagen-induced Platelet aggregation independently of its transcription factor activity

Circulation

Volumn 127, Issue 4, 2013, Pages 476-485

  Zhou, Zhou ^a   Gushiken, Francisca C ^b   Bolgiano, Doug ^a   Salsbery, Breia J ^a   Aghakasiri, Niloufar ^c   Jing, Naijie ^c   Wu, Xiaoping ^a   Vijayan, K Vinod ^c   Rumbaut, Rolando E ^c,d   Adachi, Roberto ^b   Lopez, Jose A ^a,f   Dong, Jing Fei ^a,e,f  

^a PUGET SOUND BLOOD CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e TIANJIN MEDICAL UNIVERSITY   (China)

^f UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Collagen; Hemostasis; Platelets; STAT3; Thrombosis; Transcription factors

Indexed keywords

CALCIUM; COLLAGEN; INTERLEUKIN 6; PROTEIN KINASE SYK; STAT3 PROTEIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; CALCIUM MOBILIZATION; CATALYSIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

ANIMALS; ATHEROSCLEROSIS; BLOOD PLATELETS; COLLAGEN; HEK293 CELLS; HUMANS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET AGGREGATION; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; THROMBOSIS; VASCULITIS;

EID: 84873175659     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.132126     Document Type: Article

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