Activation of mesangial cells by platelets in systemic lupus erythematosus via a CD154-dependent induction of CD40

Kidney International

Volumn 68, Issue 5, 2005, Pages 2068-2078

  Delmas, Yahsou ^a   Viallard, Jean François ^b   Solanilla, Anne ^b   Villeneuve, Julien ^b   Pasquet, Jean Max ^b   Belloc, Francis ^b   Dubus, Isabelle ^b   Déchanet Merville, Julie ^b   Merville, Pierre ^b   Blanco, Patrick ^b   Pellegrin, Jean Luc ^b   Nurden, Alan T ^b   Combe, Christian ^b   Ripoche, Jean ^b  

^a HÔPITAL PELLEGRIN   (France)

^b NONE

Author keywords

Blood platelets; CD40 ligand; Glomerular mesangium; Lupus erythematosus; Systemic; Transforming growth factor beta

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; MEMBRANE ANTIGEN; NEUTRALIZING ANTIBODY; PLATELET DERIVED GROWTH FACTOR; TETRAZOLE DERIVATIVE; THROMBIN; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ANTIGEN EXPRESSION; CELL SEPARATION; CELL STIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; MALE; MEMBRANE PERMEABILITY; MESANGIUM CELL; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTE; THROMBOCYTE ACTIVATION; UPREGULATION;

ADULT; AGED; ANTIGENS, CD40; BLOOD PLATELETS; CD40 LIGAND; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MESANGIAL CELLS; MIDDLE AGED; PLATELET ACTIVATION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 27144505450     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2005.00663.x     Document Type: Conference Paper

References (62)

1. HENN V, SLUPSKY JR, GRAFE M, et al: CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature 391:591-594, 1998
2. SLUPSKY JR, KALBAS M, WILLUWEIT A, et al: Activated platelets induce tissue factor expression on human umbilical vein endothelial cells by ligation of CD40. Thromb Haemost 80:1008-1014, 1998
3. KARMANN K, HUGHES CC, SCHECHNER J, et al: CD40 on human endothelial cells: Inducibility by cytokines and functional regulation of adhesion molecule expression. Proc Natl Acad Sci USA 92:4342-4346, 1995
4. DECHANET J, GROSSET C, TAUPIN JL, et al: CD40 ligand stimulates proinflammatory cytokine production by human endothelial cells. J Immunol 159:5640-5647, 1997
5. HOLLENBAUGH D, MISCHEL-PETTY N, EDWARDS CP, et al: Expression of functional CD40 by vascular endothelial cells. J Exp Med 182:33-40, 1995
6. VAN KOOTEN C, WOLTMAN AM, DAHA MR: Immunological function of tubular epithelial cells: The functional implications of CD40 expression. Exp Nephrol 8:203-207, 2000
7. TANAKA T, KUROIWA T, IKEUCHI H, et al: Human platelets stimulate mesangial cells to produce monocyte chemoattractant protein-1 via the CD40/CD40 ligand pathway and may amplify glomerular injury. J Am Soc Nephrol 13:2488-2496, 2002
8. CAMERON JS: Lupus nephritis. J Am Soc Nephrol 10:413-424, 1999
9. BERDEN JH, LICHT R, VAN BRUGGEN MC, et al: Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis. Curr Opin Nephrol Hypertens 8:299-306, 1999
10. CLARK WF, FRIESEN M, LINTON AL, et al: The platelet as a mediator of tissue damage in immune complex glomerulonephritis. Clin Nephrol 6:287-289, 1976
11. CLARK WF, LEWIS ML, CAMERON JS, et al: Intrarenal platelet consumption in the diffuse proliferative nephritis of systemic lupus erythematosus. Clin Sci Mol Med 49:247-252, 1975
12. ALLFORD SL, MACHIN SJ: Current understanding of the pathophysiology of thrombotic thrombocytopenic purpura. J Clin Pathol 53:497-501, 2000
13. ABBOUD HE: Role of platelet-derived growth factor in renal injury. Annu Rev Physiol 57:297-309, 1995
14. PERICO N, REMUZZI G: Role of platelet-activating factor in renal immune injury and proteinuria. Am J Nephrol 10 (Suppl 1):S98-S104, 1990
15. CAMUSSI G, TETTA C, MERONI M, et al: Localization of cationic proteins derived from platelets and polymorphonuclear neutrophils and local loss of anionic sites in glomeruli of rabbits with experimentally-induced acute serum sickness. Lab Invest 55:56-62, 1986
16. CAMUSSI G: Potential role of platelet-activating factor in renal pathophysiology. Kidney Int 29:469-477, 1986
17. 2-halide system in immune complex nephritis. Kidney Int 32:342-349, 1987
18. PARBTANI A, FRAMPTON G, YEWDALL V, et al: Platelet and plasma serotonin in glomerulonephritis. III: The nephritis of systemic lupus erythematosus. Clin Nephrol 14:164-172, 1980
19. ZOJA C, REMUZZI G: Role of platelets in progressive glomerular diseases. Pediatr Nephrol 9:495-502, 1995
20. WU X, PIPPIN J, LEFKOWITH JB: Platelets and neutrophils are critical to the enhanced glomerular arachidonate metabolism in acute nephrotoxic nephritis in rats. J Clin Invest 91:766-773, 1993
21. JOHNSON RJ, ALPERS CE, PRITZL P, et al: Platelets mediate neutrophil-dependent immune complex nephritis in the rat. J Clin Invest 82:1225-1235, 1988
22. OGAWA S, NARUSE T: Effects of various antiplatelet drugs and defibrinating agent on experimental glomerulonephritis in rats. J Lab Clin Med 99:428-441, 1982
23. IZUMINO K, IIDA H, ASAKA M, et al: Effect of the antiplatelet agents ticlopidine and dipyridamole on nephrotoxic serum nephritis in rats. Nephron 45:306-310, 1987
24. TAN EM, COHEN AS, FRIES JF, et al: The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271-1277, 1982
25. DUBUS I, VENDRELY B, CHRISTOPHE I, et al: Mycophenolic acid antagonizes the activation of cultured human mesangial cells. Kidney Int 62:857-867, 2002
26. PASQUET JM, NOURY M, NURDEN AT: Evidence that the platelet integrin alphaIIb beta3 is regulated by the integrin-linked kinase, ILK, in a PI3-kinase dependent pathway. Thromb Haemost 88:115-122, 2002
27. FIERMANN A, RAUCH BH, BRAUN M, et al: Platelet CD40 ligand (CD40L) - Subcellular localization, regulation of expression, and inhibition by clopidogrel. Platelets 12:74-82, 2001
28. NANNIZZI-ALAIMO L, ALVES VL, PHILLIPS DR: Inhibitory effects of glycoprotein IIb/IIIa antagonists and aspirin on the release of soluble CD40 ligand during platelet stimulation. Circulation 107:1123-1128, 2003
29. VAN KOOTEN C, GAILLARD C, GALIZZI JP, et al: B cells regulate expression of CD40 ligand on activated T cells by lowering the mRNA level and through the release of soluble CD40. Eur J Immunol 24:787-792, 1994
30. CONTIN C, PITARD V, ITAI T, et al: Membrane-anchored CD40 is processed by the tumor necrosis factor-alpha-converting enzyme. Implications for CD40 signaling. J Biol Chem 278:32801-32809, 2003
31. NGUYEN VT, BENVENISTE EN: Involvement of STAT-1 and ets family members in interferon-gamma induction of CD40 transcription in microglia/macrophages. J Biol Chem 275:23674-23684, 2000
32. ALDERSON MR, ARMITAGE RJ, TOUGH TW, et al: CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40. J Exp Med 178:669-674, 1993
33. KRZESZ R, WAGNER AH, CATTARUZZA M, et al: Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kappaB and signal transducer and activation of transcription-1. FEBS Lett 453:191-196, 1999
34. KUROIWA T, LEE EG, DANNING CL, et al: CD40 ligand-activated human monocytes amplify glomerular inflammatory responses through soluble and cell-to-cell contact-dependent mechanisms. J Immunol 163:2168-2175, 1999
35. SCHWARTING A, WADA T, KINOSHITA K, et al: IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice. J Immunol 161:494-503, 1998
36. KUROIWA T, LEE EG: Cellular interactions in the pathogenesis of lupus nephritis: The role of T cells and macrophages in the amplification of the inflammatory process in the kidney. Lupus 7:597-603, 1998
37. KATO K, SANTANA-SAHAGUN E, RASSENTI LZ, et al: The soluble CD40 ligand sCD154 in systemic lupus erythematosus. J Clin Invest 104:947-955, 1999
38. HENN V, STEINBACH S, BUCHNER K, et al: The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. Blood 98:1047-1054, 2001
39. MAY AE, KALSCH T, MASSBERG S, et al: Engagement of glycoprotein IIb/IIIa (alpha(IIb)beta3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells. Circulation 106:2111-2117, 2002
40. CAMUSSI G: Interactive effects of tumor necrosis factor and platelet-activating factor in the pathogenesis of glomerular injury. Lab Invest 70:435-436, 1994
41. COLASANTI G, MOREL MAROGER L, D'AMICO G: Deposition of fibrin-stabilizing factor (F XIIIA and S), fibrinogen-related antigens, fibrinogen degradation products (FDPd and FDPe) and antihemolytic factor (F VIII) in renal disease: analysis of 161 cases by immunofluorescence microscopy. Clin Nephrol 28:28-34, 1987
42. MCCUTCHEON J, EVANS B, D'CRUZ DP, et al: Fibrin deposition in SLE glomerulonephritis. Lupus 2:99-103, 1993
43. TAKEMURA T, YOSHIOKA K, AKANO N, et al: Glomerular deposition of cross-linked fibrin in human kidney diseases. Kidney Int 32:102-111, 1987
44. CAMUSSI G, TETTA C, MAZZUCCO G, et al: Platelet cationic proteins are present in glomeruli of lupus nephritis patients. Kidney Int 30:555-565, 1986
45. NAGAHAMA M, NOMURA S, OZAKI Y, et al: Platelet activation markers and soluble adhesion molecules in patients with systemic lupus erythematosus. Autoimmunity 33:85-94, 2001
46. JOSEPH JE, HARRISON P, MACKIE IJ, et al: Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis. Br J Haematol 115:451-459, 2001
47. LATTA H: An approach to the structure and function of the glomerular mesangium. J Am Soc Nephrol 2:S65-S73, 1992
48. ALEXOPOULOS E, SERON D, HARTLEY RB, et al: Lupus nephritis: Correlation of interstitial cells with glomerular function. Kidney Int 37:100-109, 1990
49. OOTAKA T, SAITO T, SOMA J, et al: Mechanism of infiltration and activation of glomerular monocytes/macrophages in IgA nephropathy. Am J Nephrol 17:137-145, 1997
50. BRADY HR: Leukocyte adhesion molecules: Potential targets for therapeutic intervention in kidney diseases. Curr Opin Nephrol Hypertens 2:171-182, 1993
51. NIKOLIC-PATERSON DJ, LAN HY, HILL PA, et al: Macrophages in renal injury. Kidney Int (Suppl) 45:S79-S82, 1994
52. LOWENHAUPT RW, SILBERSTEIN EB, SPERLING MI, et al: A quantitative method to measure human platelet chemotaxis using indium-111-oxine-labeled gel-filtered platelets. Blood 60:1345-1352, 1982
53. BORDER WA, NOBLE NA, YAMAMOTO T, et al: Antagonists of transforming growth factor-beta: A novel approach to treatment of glomerulonephritis and prevention of glomerulosclerosis. Kidney Int 41:566-570, 1992
54. BORDER WA, OKUDA S, LANGUINO LR, et al: Transforming growth factor-beta regulates production of proteoglycans by mesangial cells. Kidney Int 37:689-695, 1990
55. OKUDA S, LANGUINO LR, RUOSLAHTI E, et al: Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix. J Clin Invest 86:453-462, 1990
56. CONTIN C, PITARD V, DELMAS Y, et al: Potential role of soluble CD40 in the humoral immune response impairment of uraemic patients. Immunology 110:131-140, 2003
57. SCHWABE RF, ENGELMANN H, HESS S, et al: Soluble CD40 in the serum of healthy donors, patients with chronic renal failure, haemodialysis and chronic ambulatory peritoneal dialysis (CAPD) patients. Clin Exp Immunol 117:153-158, 1999
58. UHM W, NA K, SONG G, et al: Cytokine balance in kidney tissue from lupus nephritis patients. Rheumatology 42:935-938, 2003
59. YELLIN MJ, D'AGATI V, PARKINSON G, et al: Immunohistologic analysis of renal CD40 and CD40L expression in lupus nephritis and other glomerulonephritides. Arthritis Rheum 40:124-134, 1997
60. VAN KOOTEN C, VAN DER LINDE X, WOLTMAN AM, et al: Synergistic effect of interleukin-1 and CD40L on the activation of human renal tubular epithelial cells. Kidney Int 56:41-51, 1999
61. KAIRAITIS L, WANG Y, ZHENG L, et al: Blockade of CD40-CD40 ligand protects against renal injury in chronic proteinuric renal disease. Kidney Int 64:1265-1272, 2003
62. KALLED SL, CUTLER AH, DATTA SK, et al: Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function. J Immunol 160:2158-2165, 1998