How to Contain Artemisinin- and Multidrug-Resistant Falciparum Malaria

Trends in Parasitology

Volumn 33, Issue 5, 2017, Pages 353-363

  Dondorp, Arjen M ^a,b   Smithuis, Frank M ^a,b,c   Woodrow, Charley ^a,b   Seidlein, Lorenz von ^a,b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Myanmar Oxford Clinical Research Unit   (Myanmar)

Author keywords

artemisinin and multi drug resistance; containment; Falciparum malaria; Greater Mekong subregion; malaria elimination

Indexed keywords

ARTEMISININ; IVERMECTIN; PRIMAQUINE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE;

HEALTH CARE PERSONNEL; HUMAN; MALARIA CONTROL; MALARIA FALCIPARUM; MASS SCREENING; MULTIDRUG RESISTANCE; NONHUMAN; PARASITE CLEARANCE; REVIEW; VACCINATION; VECTOR CONTROL; CAMBODIA; DISEASE ERADICATION; DRUG EFFECTS; DRUG RESISTANCE; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM;

ANTIMALARIALS; ARTEMISININS; CAMBODIA; DISEASE ERADICATION; DRUG RESISTANCE; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM;

EID: 85011628834     PISSN: 14714922     EISSN: 14715007     Source Type: Journal    
DOI: 10.1016/j.pt.2017.01.004     Document Type: Review

References (82)

1. 1 Noedl, H., Artemisinin-resistant malaria in Asia. N. Engl. J. Med. 361 (2009), 540–541.
2. 2 Dondorp, A.M., Artemisinin resistance in Plasmodium falciparum malaria. N. Engl. J. Med. 361 (2009), 455–467.
3. 3 Ariey, F., A molecular marker of artemisinin-resistant Plasmodium falciparum malaria. Nature 505 (2014), 50–55.
4. 4 Stepniewska, K., White, N.J., Some considerations in the design and interpretation of antimalarial drug trials in uncomplicated falciparum malaria. Malaria J., 5, 2006, 127.
5. 5 Dondorp, A.M., The threat of artemisinin-resistant malaria. N. Engl. J. Med. 365 (2011), 1073–1075.
6. 6 Flegg, J.A., Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator. Malaria J., 10, 2011, 339.
7. 7 White, N.J., The parasite clearance curve. Malaria J., 10, 2011, 278.
8. 8 Mishra, N., Declining efficacy of artesunate plus sulphadoxine-pyrimethamine in northeastern India. Malaria J., 13, 2014, 284.
9. 9 Gadalla, N.B., Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine-pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern Sudan. Malaria J., 12, 2013, 255.
10. 10 Phyo, A.P., et al. Declining efficacy of artemisinin combination therapy against P. falciparum malaria on the Thai–Myanmar border (2003-2013): the role of parasite genetic factors. Clin. Infect. Dis. 63 (2016), 784–791.
11. 11 Amaratunga, C., Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study. Lancet Infect. Dis. 16 (2016), 357–365.
12. 12 Leang, R., Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010. Antimicrob. Agents Chemother. 57 (2013), 818–826.
13. 13 Saunders, D.L., Dihydroartemisinin-piperaquine failure in Cambodia. N. Engl. J. Med. 371 (2014), 484–485.
14. 14 Leang, R., Evidence of Plasmodium falciparum malaria multidrug resistance to artemisinin and piperaquine in Western Cambodia: dihydroartemisinin-piperaquine open-label multicenter clinical assessment. Antimicrob. Agents Chemother. 59 (2015), 4719–4726.
15. 15 Duru, V., Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations. BMC Med., 13, 2015, 305.
16. 16 Lon, C., et al. Efficacy of two versus three-day regimens of dihydroartemisinin-piperaquine for uncomplicated malaria in military personnel in northern Cambodia: an open-label randomized trial. PLoS One, 9, 2014, e93138.
17. 17 Amato, R., et al. Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study. Lancet Infect. Dis., 2016, 10.1016/S1473- 3099(16)30409-1 Published online November 3, 2016.
18. 18 Witkowski, B., et al. A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a genotype-phenotype association study. Lancet Infect. Dis., 2016, 10.1016/S1473-3099(16)30415-7 Published online November 3, 2016.
19. 19 Bousema, T., Drakeley, C., Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination. Clin. Microbiol. Rev. 24 (2011), 377–410.
20. 20 Ashley, E.A., Spread of artemisinin resistance in Plasmodium falciparum malaria. N. Engl. J. Med. 371 (2014), 411–423.
21. 21 Takala-Harrison, S., Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia. J. Infect. Dis. 211 (2014), 670–679.
22. 22 Miotto, O., Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia. Nat. Genet. 45 (2013), 648–655.
23. 23 Imwong, M., et al. A molecular epidemiology observational study of the recent transnational spread of artemisinin resistant P. falciparum in the Greater Mekong Subregion. Lancet Infect. Dis., 2017, 10.1016/S1473-3099(17)30048-8.
24. 24 White, N.J., Can new treatment developments combat resistance in malaria?. Exp. Opin. Pharmacother. 17 (2016), 1303–1307.
25. 25 WHO, Global Plan for Artemisinin Resistance Containment. 2011, WHO Press.
26. 26 WHO, Strategy for Malaria Elimination in the GMS (2015–2030). 2015, WHO.
27. 27 Maude, R.J., The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia. Malaria J., 8, 2009, 31.
28. 28 WHO, World Malaria Report 2015. First published 2015., 2015 http://www.who.int/malaria/publications/world-malaria-report-2015/report/en/.
29. 29 Imwong, M., An outbreak of artemisinin resistant falciparum malaria in Eastern Thailand. Sci. Rep., 5, 2015, 17412.
30. 30 Wootton, J.C., Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Nature 418 (2002), 320–323.
31. 31 WHO, Malaria Elimination: A Field Manual for Low and Moderate Endemic Countries. 2007, WHO.
32. 32 Cui, L., Challenges and prospects for malaria elimination in the Greater Mekong Subregion. Acta Trop. 121 (2012), 240–245.
33. 33 Yasuoka, J., Scale-up of community-based malaria control can be achieved without degrading community health workers’ service quality: the Village Malaria Worker project in Cambodia. Malaria J., 11, 2012, 4.
34. 34 Lwin, M.M., Improving malaria knowledge and practices in rural Myanmar through a village health worker intervention: a cross-sectional study. Malaria J., 13, 2014, 5.
35. 35 Canavati, S.E., Village malaria worker performance key to the elimination of artemisinin-resistant malaria: a Western Cambodia health system assessment. Malaria J., 15, 2016, 282.
36. 36 Canavati, S.E., High mobility, low access thwarts interventions among seasonal workers in the Greater Mekong Sub-region: lessons from the malaria containment project. Malaria J., 15, 2016, 434.
37. 37 Lubell, Y., Performance of C-reactive protein and procalcitonin to distinguish viral from bacterial and malarial causes of fever in Southeast Asia. BMC Infect. Dis., 15, 2015, 511.
38. 38 Lubell, Y., Modelling the impact and cost-effectiveness of biomarker tests as compared with pathogen-specific diagnostics in the management of undifferentiated fever in remote tropical settings. PLoS One, 11, 2016, e0152420.
39. 39 Prue, C.S., Mobile phones improve case detection and management of malaria in rural Bangladesh. Malaria J., 12, 2013, 48.
40. 40 Landier, J., The role of early detection and treatment in malaria elimination. Malaria J., 15, 2016, 363.
41. 41 Tainchum, K., Anopheles species diversity and distribution of the malaria vectors of Thailand. Trends Parasitol. 31 (2015), 109–119.
42. 42 St Laurent, B., et al. Artemisinin-resistant Plasmodium falciparum clinical isolates can infect diverse mosquito vectors of Southeast Asia and Africa. Nat. Commun., 6, 2015, 8614.
43. 43 Hii, J., Rueda, L.M., Malaria vectors in the Greater Mekong Subregion: overview of malaria vectors and remaining challenges. Southeast Asian J. Trop. Med. Pub. Health 44:Suppl. 1 (2013), 73–165.
44. 44 Sluydts, V., Efficacy of topical mosquito repellent (picaridin) plus long-lasting insecticidal nets versus long-lasting insecticidal nets alone for control of malaria: a cluster randomised controlled trial. Lancet Infect. Dis. 16 (2016), 1169–1177.
45. 45 Smithuis, F.M., The effect of insecticide-treated bed nets on the incidence and prevalence of malaria in children in an area of unstable seasonal transmission in western Myanmar. Malaria J., 12, 2013, 363.
46. 46 Lengeler, C., Insecticide-treated bednets and curtains for preventing malaria. Cochrane Database Syst. Rev., 2, 2000, CD000363.
47. 47 Pluess, B., et al. Indoor residual spraying for preventing malaria. Cochrane Database Syst. Rev., 4, 2010 CD006657.
48. 48 Strode, C., The impact of pyrethroid resistance on the efficacy of insecticide-treated bed nets against African anopheline mosquitoes: systematic review and meta-analysis. PLoS Med., 11, 2014, e1001619.
49. 49 Knudsen, J., von Seidlein, L., Healthy Homes in Tropical Zones: Improving Rural Housing in Asia and Africa. 2014, Edition Axel Menges.
50. 50 Doucoure, S., Drame, P.M., Salivary biomarkers in the control of mosquito-borne diseases. Insects 6 (2015), 961–976.
51. 51 Imwong, M., The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand-Myanmar border areas, Cambodia, and Vietnam. Malaria J., 14, 2015, 381.
52. 52 Phommasone, K., Asymptomatic Plasmodium infections in 18 villages of southern Savannakhet Province, Lao PDR (Laos). Malaria J., 15, 2016, 296.
53. 53 Imwong, M., Numerical distributions of parasite densities during asymptomatic malaria. J. Infect. Dis. 213 (2016), 1322–1329.
54. 54 Bousema, T., Asymptomatic malaria infections: detectability, transmissibility and public health relevance. Nature Rev. Microbiol. 12 (2014), 833–840.
55. 55 Newby, G., Review of mass drug administration for malaria and its operational challenges. Am. J. Trop. Med. Hyg. 93 (2015), 125–134.
56. 56 Ruktanonchai, N.W., Census-derived migration data as a tool for informing malaria elimination policy. Malaria J., 15, 2016, 273.
57. 57 Kaneko, A., Malaria eradication on islands. Lancet 356 (2000), 1560–1564.
58. 58 Adhikari, B., Community engagement and population coverage in mass anti-malarial administrations: a systematic literature review. Malaria J., 15, 2016, 523.
59. 59 Kajeechiwa, L., The acceptability of mass administrations of anti-malarial drugs as part of targeted malaria elimination in villages along the Thai-Myanmar border. Malaria J., 15, 2016, 494.
60. 60 Foy, B.D., Endectocides for malaria control. Trends Parasitol. 27 (2011), 423–428.
61. 61 Chaccour, C.J., Establishment of the Ivermectin Research for Malaria Elimination Network: updating the research agenda. Malaria J., 14, 2015, 243.
62. 62 Halliday, K.E., Impact of intermittent screening and treatment for malaria among school children in Kenya: a cluster randomised trial. PLoS Med., 11, 2014, e1001594.
63. 63 Tiono, A.B., Dynamics of malaria transmission and susceptibility to clinical malaria episodes following treatment of Plasmodium falciparum asymptomatic carriers: results of a cluster-randomized study of community-wide screening and treatment, and a parallel entomology study. BMC Infect. Dis., 13, 2013, 535.
64. 64 Tiono, A.B., A controlled, parallel, cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso. Malaria J., 12, 2013, 79.
65. 65 von Seidlein, L., The failure of screening and treating as a malaria elimination strategy. PLoS Med., 11, 2014, e1001595.
66. 66 Slater, H.C., Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies. Nature 528 (2015), S94–S101.
67. 67 Lin, J.T., Microscopic Plasmodium falciparum gametocytemia and infectivity to mosquitoes in Cambodia. J. Infect. Dis. 213 (2016), 1491–1494.
68. 68 Hustedt, J., Reactive case-detection of malaria in Pailin Province, Western Cambodia: lessons from a year-long evaluation in a pre-elimination setting. Malaria J., 15, 2016, 132.
69. 69 Parker, D.M., Limitations of malaria reactive case detection in an area of low and unstable transmission on the Myanmar-Thailand border. Malaria J. 15 (2016), 571–575.
70. 70 WHO, Meeting of the Strategic Advisory Group of Experts on immunization, October 2015 – conclusions and recommendations. Wkly Epidem. Rec. 90 (2015), 693–696.
71. 71 RTS,S Clinical Trials Partnership, Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. Lancet 386 (2015), 31–45.
72. 72 Gosling, R., von Seidlein, L., The future of the RTS,S/AS01 malaria vaccine: an alternative development plan. PLoS Med., 13, 2016, e1001994.
73. 73 Erhart, A., Epidemiology of forest malaria in central Vietnam: a large scale cross-sectional survey. Malaria J., 4, 2005, 58.
74. 74 Thanh, P.V., Epidemiology of forest malaria in Central Vietnam: the hidden parasite reservoir. Malaria J., 14, 2015, 86.
75. 75 Eyles, D.E., Studies on malaria and Anopheles balabacensis in Cambodia. Bull. World Hlth Organ. 30 (1964), 7–21.
76. 76 Peeters Grietens, K., Characterizing types of human mobility to inform differential and targeted malaria elimination strategies in Northeast Cambodia. Sci. Rep., 5, 2015, 16837.
77. 77 Guyant, P., Malaria and the mobile and migrant population in Cambodia: a population movement framework to inform strategies for malaria control and elimination. Malaria J., 14, 2015, 252.
78. 78 Sochantha, T., Personal protection by long-lasting insecticidal hammocks against the bites of forest malaria vectors. Trop. Med. Int. Health 15 (2010), 336–341.
79. 79 Silal, S.P., Hitting a moving target: a model for malaria elimination in the presence of population movement. PLoS One, 10, 2015, e0144990.
80. 80 Griffin, J.T., Potential for reduction of burden and local elimination of malaria by reducing Plasmodium falciparum malaria transmission: a mathematical modelling study. Lancet Infect. Dis. 16 (2016), 465–472.
81. 81 Leang, R., Efficacy and safety of pyronaridine-artesunate for treatment of uncomplicated Plasmodium falciparum malaria in Western Cambodia. Antimicrob. Agents Chemother. 60 (2016), 3884–3890.
82. 82 Woodrow, C.J., White, N.J., The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread. FEMS Microbiol. Rev. 41 (2017), 34–48.