Oxidative DNA damage induces hypomethylation in a compromised base excision repair colorectal tumourigenesis

British Journal of Cancer

Volumn 116, Issue 6, 2017, Pages 793-801

  Furlan, Daniela ^a   Trapani, Davide ^a   Berrino, Enrico ^b   Debernardi, Carla ^b   Panero, Mara ^b   Libera, Laura ^a   Sahnane, Nora ^a   Riva, Cristina ^a   Tibiletti, Maria Grazia ^a   Sessa, Fausto ^a   Sapino, Anna ^b   Venesio, Tiziana ^b  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b CANDIOLO CANCER INSTITUTE   (Italy)

Author keywords

BER; colorectal adenomas; DNA hypomethylation; LINE 1 LINE 1 MET methylation; MUTYH associated polyposis; oxidative DNA damage

Indexed keywords

DNA;

ADULT; AGED; ARTICLE; CANCER PATIENT; CLINICAL ARTICLE; COLON CARCINOGENESIS; COLORECTAL ADENOMA; COLORECTAL CARCINOMA; CONTROLLED STUDY; DEMETHYLATION; DNA DAMAGE; DNA METHYLATION; EPIGENETICS; EXCISION REPAIR; FAMILIAL COLON POLYPOSIS; FEMALE; GENE MUTATION; HUMAN; LONG INTERSPERSED REPEAT; MALE; MASS SPECTROMETRY; MIDDLE AGED; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PYROSEQUENCING; YOUNG ADULT; ADENOMA; CANCER STAGING; CARCINOGENESIS; CASE CONTROL STUDY; COLORECTAL TUMOR; DNA REPAIR; FOLLOW UP; GENETIC PREDISPOSITION; GENETICS; OXIDATIVE STRESS; PATHOLOGY; PROGNOSIS; VERY ELDERLY;

ADENOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOGENESIS; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; OXIDATIVE STRESS; PROGNOSIS;

EID: 85011263027     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2017.9     Document Type: Article

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