-
1
-
-
84885993027
-
MAITs, MR1 and Vitamin B metabolites
-
Birkinshaw, R.W., Kjer-Nielsen, L., Eckle, S.B.,McCluskey, J. &Rossjohn, J. MAITs, MR1 and vitamin B metabolites. Curr. Opin. Immunol. 26, 7-13 (2014).
-
(2014)
Curr. Opin. Immunol.
, vol.26
, pp. 7-13
-
-
Birkinshaw, R.W.1
Kjer-Nielsen, L.2
Eckle, S.B.3
McCluskey, J.4
Rossjohn, J.5
-
2
-
-
84900551126
-
T-cell activation by transitory neo-antigens derived from distinct microbial pathways
-
Corbett, A.J. et al. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature 509, 361-365 (2014).
-
(2014)
Nature
, vol.509
, pp. 361-365
-
-
Corbett, A.J.1
-
3
-
-
65949083560
-
Where do MAIT cells fit in the family of unconventional T cells
-
Gapin, L. Where do MAIT cells fit in the family of unconventional T cells? PLoS Biol. 7, e70 (2009).
-
(2009)
PLoS Biol.
, vol.7
, pp. e70
-
-
Gapin, L.1
-
4
-
-
84870284140
-
MR1presents microbial vitaminBmetabolites to MAIT cells
-
Kjer-Nielsen, L. et al.MR1presents microbial vitaminBmetabolites to MAIT cells. Nature 491, 717-723 (2012).
-
(2012)
Nature
, vol.491
, pp. 717-723
-
-
Kjer-Nielsen, L.1
-
5
-
-
79955612071
-
Mucosal-associated invariant T cells: Unconventional development and function
-
Le Bourhis, L. et al. Mucosal-associated invariant T cells: unconventional development and function. Trends Immunol. 32, 212-218 (2011).
-
(2011)
Trends Immunol.
, vol.32
, pp. 212-218
-
-
Le Bourhis, L.1
-
6
-
-
0037434974
-
Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1
-
Treiner, E. et al. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 422, 164-169 (2003).
-
(2003)
Nature
, vol.422
, pp. 164-169
-
-
Treiner, E.1
-
7
-
-
84900842237
-
Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRbeta repertoire
-
Lepore, M. et al. Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRbeta repertoire. Nat. Commun. 5, 3866 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 3866
-
-
Lepore, M.1
-
8
-
-
84885981736
-
Antigen-loaded MR1 tetramers define Tcell receptor heterogeneity in mucosal-associated invariant T cells
-
Reantragoon, R. et al. Antigen-loaded MR1 tetramers define Tcell receptor heterogeneity in mucosal-associated invariant T cells. J. Exp. Med. 210, 2305-2320 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2305-2320
-
-
Reantragoon, R.1
-
9
-
-
0033591698
-
An invariant T cell receptor alpha chain defines a novel TAPindependent major histocompatibility complex class Ib-restricted alpha/ beta T cell subpopulation in mammals
-
Tilloy, F. et al. An invariant T cell receptor alpha chain defines a novel TAPindependent major histocompatibility complex class Ib-restricted alpha/ beta T cell subpopulation in mammals. J. Exp. Med. 189, 1907-1921 (1999).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1907-1921
-
-
Tilloy, F.1
-
10
-
-
84855275402
-
Mucosal-associated invariant Tcells promote inflammation and exacerbate disease in murine models of arthritis
-
Chiba, A. et al. Mucosal-associated invariant Tcells promote inflammation and exacerbate disease in murine models of arthritis. Arthritis Rheum. 64, 153-161 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 153-161
-
-
Chiba, A.1
-
11
-
-
77954701928
-
Human mucosal associated invariant T cells detect bacterially infected cells
-
Gold, M.C. et al. Human mucosal associated invariant T cells detect bacterially infected cells. PLoS Biol. 8, e1000407 (2010).
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000407
-
-
Gold, M.C.1
-
12
-
-
77954914800
-
Antimicrobial activity of mucosal-associated invariant T cells
-
Le Bourhis, L. et al. Antimicrobial activity of mucosal-associated invariant T cells. Nat. Immunol. 11, 701-708 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 701-708
-
-
Le Bourhis, L.1
-
13
-
-
84882380657
-
MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection
-
Meierovics, A., Yankelevich, W.J. &Cowley, S.C. MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection. Proc. Natl. Acad. Sci. USA 110, E3119-E3128 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. E3119-E3128
-
-
Meierovics, A.1
Yankelevich, W.J.2
Cowley, S.C.3
-
14
-
-
84946716473
-
Mucosal-associated invariant Tcell-rich congenic mouse strain allows functional evaluation
-
Cui, Y. et al. Mucosal-associated invariant Tcell-rich congenic mouse strain allows functional evaluation. J. Clin. Invest. 125, 4171-4185 (2015).
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 4171-4185
-
-
Cui, Y.1
-
15
-
-
31144432872
-
MR1-restricted Valpha 19i mucosal-associated invariant Tcells are innate Tcells in the gut lamina propria that provide a rapid and diverse cytokine response
-
Kawachi, I., Maldonado, J., Strader, C.and Gilfillan, S. MR1-restricted Valpha 19i mucosal-associated invariant Tcells are innate Tcells in the gut lamina propria that provide a rapid and diverse cytokine response. J. Immunol. 176, 1618-1627 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 1618-1627
-
-
Kawachi, I.1
Maldonado, J.2
Strader, C.3
Gilfillan, S.4
-
16
-
-
65949112929
-
Stepwise development of MAITcells in mouse and human
-
Martin, E. et al. Stepwise development of MAITcells in mouse and human. PLoS Biol. 7, e54 (2009).
-
(2009)
PLoS Biol.
, vol.7
, pp. e54
-
-
Martin, E.1
-
17
-
-
84880288515
-
Recognition of vitaminBmetabolites by mucosal-associated invariant T cells
-
Patel, O. et al. Recognition of vitaminBmetabolites by mucosal-associated invariant T cells. Nat. Commun. 4, 2142 (2013).
-
(2013)
Nat. Commun.
, vol.4
, pp. 2142
-
-
Patel, O.1
-
18
-
-
84905122431
-
A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
-
Eckle, S.B. et al. A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. J. Exp. Med. 211, 1585-1600 (2014).
-
(2014)
J. Exp. Med.
, vol.211
, pp. 1585-1600
-
-
Eckle, S.B.1
-
19
-
-
84958878687
-
Diversity of T cells restricted by the MHC class I-related molecule MR1 facilitates differential antigen recognition
-
Gherardin, N.A. et al. Diversity of T cells restricted by the MHC class I-related molecule MR1 facilitates differential antigen recognition. Immunity 44, 32-45 (2016).
-
(2016)
Immunity
, vol.44
, pp. 32-45
-
-
Gherardin, N.A.1
-
20
-
-
84905118556
-
MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage
-
Gold, M.C. et al. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage. J. Exp. Med. 211, 1601-1610 (2014).
-
(2014)
J. Exp. Med.
, vol.211
, pp. 1601-1610
-
-
Gold, M.C.1
-
21
-
-
84944872887
-
Identification of phenotypically and functionally heterogeneous mouse mucosal associated invariant T cells using MR1 tetramers
-
Rahimpour, A. et al. Identification of phenotypically and functionally heterogeneous mouse mucosal associated invariant T cells using MR1 tetramers. J. Exp. Med. 20, 1095-1108 (2015).
-
(2015)
J. Exp. Med.
, vol.20
, pp. 1095-1108
-
-
Rahimpour, A.1
-
22
-
-
84936817615
-
Functional heterogeneity and antimycobacterial effects of mouse mucosal-associated invariant T cells specific for riboflavin metabolites
-
Sakala, I.G. et al. Functional heterogeneity and antimycobacterial effects of mouse mucosal-associated invariant T cells specific for riboflavin metabolites. J. Immunol. 195, 587-601 (2015).
-
(2015)
J. Immunol.
, vol.195
, pp. 587-601
-
-
Sakala, I.G.1
-
23
-
-
84911394806
-
Cellular requirements for systemic control of Salmonella enterica serovar Typhimurium infections in mice
-
Kupz, A., Bedoui, S. &Strugnell, R.A. Cellular requirements for systemic control of Salmonella enterica serovar Typhimurium infections in mice. Infect. Immun. 82, 4997-5004 (2014).
-
(2014)
Infect. Immun.
, vol.82
, pp. 4997-5004
-
-
Kupz, A.1
Bedoui, S.2
Strugnell, R.A.3
-
24
-
-
0026783811
-
Characterization of a Salmonella typhimurium aro vaccine strain expressing the P.69 antigen of Bordetella pertussis
-
Strugnell, R. et al. Characterization of a Salmonella typhimurium aro vaccine strain expressing the P.69 antigen of Bordetella pertussis. Infect. Immun. 60, 3994-4002 (1992).
-
(1992)
Infect. Immun.
, vol.60
, pp. 3994-4002
-
-
Strugnell, R.1
-
25
-
-
79954985832
-
Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant Tcells
-
Chua, W.J. et al. Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant Tcells. J. Immunol. 186, 4744-4750 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 4744-4750
-
-
Chua, W.J.1
-
26
-
-
20444379258
-
Evidence for MR1 antigen presentation to mucosalassociated invariant T cells
-
Huang, S. et al. Evidence for MR1 antigen presentation to mucosalassociated invariant T cells. J. Biol. Chem. 280, 21183-21193 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 21183-21193
-
-
Huang, S.1
-
27
-
-
7444271904
-
A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic Tcell responses
-
Jackson, D.C. et al. A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic Tcell responses. Proc. Natl. Acad. Sci. USA 101, 15440-15445 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15440-15445
-
-
Jackson, D.C.1
-
28
-
-
33845352530
-
Lipid-containing mimetics of natural triggers of innate immunity as CTL-inducing influenza vaccines
-
Lau, Y.F. et al. Lipid-containing mimetics of natural triggers of innate immunity as CTL-inducing influenza vaccines. Int. Immunol. 18, 1801-1813 (2006).
-
(2006)
Int. Immunol.
, vol.18
, pp. 1801-1813
-
-
Lau, Y.F.1
-
29
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou, L., Holt, A.C., Medzhitov, R. &Flavell, R.A. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413, 732-738 (2001).
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
30
-
-
0035477969
-
Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells
-
Takeshita, F. et al. Cutting edge: role of Toll-like receptor 9 in CpG DNA-induced activation of human cells. J. Immunol. 167, 3555-3558 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 3555-3558
-
-
Takeshita, F.1
-
31
-
-
79251585935
-
Human MAIT cells are xenobiotic-resistant, tissuetargeted, CD161hi IL-17-secreting Tcells
-
Dusseaux, M. et al. Human MAIT cells are xenobiotic-resistant, tissuetargeted, CD161hi IL-17-secreting Tcells. Blood 117, 1250-1259 (2011).
-
(2011)
Blood
, vol.117
, pp. 1250-1259
-
-
Dusseaux, M.1
-
32
-
-
69749125286
-
PLZF is a regulator of homeostatic and cytokine-induced myeloid development
-
Doulatov, S. et al. PLZF is a regulator of homeostatic and cytokine-induced myeloid development. Genes Dev. 23, 2076-2087 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 2076-2087
-
-
Doulatov, S.1
-
33
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, I.I. et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126, 1121-1133 (2006).
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
-
34
-
-
0033825825
-
Management of recurrent hepatitisC after liver transplantation: A concise review
-
Szabo, G., Katz, E. and Bonkovsky,H.L.Management of recurrent hepatitisC after liver transplantation: a concise review. Am. J. Gastroenterol. 95, 2164-2170 (2000).
-
(2000)
Am. J. Gastroenterol.
, vol.95
, pp. 2164-2170
-
-
Szabo, G.1
Katz, E.2
Bonkovsky, H.L.3
-
35
-
-
78650306567
-
T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORgammat
-
Lazarevic, V. et al. T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORgammat. Nat. Immunol. 12, 96-104 (2011).
-
(2011)
Nat. Immunol.
, vol.12
, pp. 96-104
-
-
Lazarevic, V.1
-
36
-
-
33748174156
-
T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype
-
Mathur, A.N. et al. T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood 108, 1595-1601 (2006).
-
(2006)
Blood
, vol.108
, pp. 1595-1601
-
-
Mathur, A.N.1
-
37
-
-
78650671831
-
STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and-independent mechanisms
-
Villarino, A.V.,Gallo, E. &Abbas, A.K. STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and-independent mechanisms. J. Immunol. 185, 6461-6471 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 6461-6471
-
-
Villarino, A.V.1
Gallo, E.2
Abbas, A.K.3
-
38
-
-
79960884563
-
The shedding of CD62L (L-selectin) regulates the acquisition of lytic activity in human tumor reactive T lymphocytes
-
Yang, S., Liu, F., Wang, Q.J., Rosenberg, S.A. &Morgan, R.A. The shedding of CD62L (L-selectin) regulates the acquisition of lytic activity in human tumor reactive T lymphocytes. PLoS One 6, e22560 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e22560
-
-
Yang, S.1
Liu, F.2
Wang, Q.J.3
Rosenberg, S.A.4
Morgan, R.A.5
-
39
-
-
84892453502
-
CD161(+ +) CD8(+) T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner
-
Ussher, J.E. et al. CD161(+ +) CD8(+) T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner. Eur. J. Immunol. 44, 195-203 (2014).
-
(2014)
Eur. J. Immunol.
, vol.44
, pp. 195-203
-
-
Ussher, J.E.1
-
40
-
-
84922693685
-
MAITcells are licensed through granzyme exchange to kill bacterially sensitized targets
-
Kurioka, A. et al. MAITcells are licensed through granzyme exchange to kill bacterially sensitized targets. Mucosal Immunol. 8, 429-440 (2015).
-
(2015)
Mucosal Immunol.
, vol.8
, pp. 429-440
-
-
Kurioka, A.1
-
41
-
-
84872772721
-
Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets
-
Sathaliyawala, T. et al. Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity 38, 187-197 (2013).
-
(2013)
Immunity
, vol.38
, pp. 187-197
-
-
Sathaliyawala, T.1
-
42
-
-
84924386358
-
Cutting edge: CD69 interference with sphingosine-1-phosphate receptor function regulates peripheral T cell retention
-
Mackay, L.K. et al. Cutting edge: CD69 interference with sphingosine-1-phosphate receptor function regulates peripheral T cell retention. J. Immunol. 194, 2059-2063 (2015).
-
(2015)
J. Immunol.
, vol.194
, pp. 2059-2063
-
-
Mackay, L.K.1
-
43
-
-
84867608542
-
Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress
-
Gold, M.C. et al. Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress. Mucosal Immunol. 6, 35-44 (2013).
-
(2013)
Mucosal Immunol.
, vol.6
, pp. 35-44
-
-
Gold, M.C.1
-
44
-
-
84865967870
-
Intranasal administration of the TLR2 agonist Pam2Cys provides rapid protection against influenza in mice
-
Tan, A.C. et al. Intranasal administration of the TLR2 agonist Pam2Cys provides rapid protection against influenza in mice. Mol. Pharm. 9, 2710-2718 (2012).
-
(2012)
Mol. Pharm.
, vol.9
, pp. 2710-2718
-
-
Tan, A.C.1
-
45
-
-
0019407618
-
Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
-
Hoiseth, S.K. &Stocker, B.A.D. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature 291, 238-239 (1981).
-
(1981)
Nature
, vol.291
, pp. 238-239
-
-
Hoiseth, S.K.1
Stocker, B.A.D.2
-
46
-
-
0026775049
-
Genotypic and phenotypic characterization of an aroD deletion-attenuated Escherichia coli K12-Shigella flexneri hybrid vaccine expressing S.flexneri 2a somatic antigen
-
Newland, J.W., Hale, T.L. &Formal, S.B. Genotypic and phenotypic characterization of an aroD deletion-attenuated Escherichia coli K12-Shigella flexneri hybrid vaccine expressing S. flexneri 2a somatic antigen. Vaccine 10, 766-776 (1992).
-
(1992)
Vaccine
, vol.10
, pp. 766-776
-
-
Newland, J.W.1
Hale, T.L.2
Formal, S.B.3
|