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Volumn 18, Issue 12, 2006, Pages 1801-1813

Lipid-containing mimetics of natural triggers of innate immunity as CTL-inducing influenza vaccines

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; EPITOPE; GAMMA INTERFERON; INFLUENZA VACCINE; LIPOPEPTIDE; TOLL LIKE RECEPTOR 2;

EID: 33845352530     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxl114     Document Type: Article
Times cited : (55)

References (51)
  • 1
    • 0017620583 scopus 로고
    • Biological, genetic and biochemical characterization of a coldadapted recombinant A/Victoria/3/75 virus and its evaluation in volunteers
    • Maassab, H. F., Cox, N. J., Murphy, B. R. and Kendal, A. P. 1977. Biological, genetic and biochemical characterization of a coldadapted recombinant A/Victoria/3/75 virus and its evaluation in volunteers. Dev. Biol. Stand. 39:25.
    • (1977) Dev. Biol. Stand. , vol.39 , pp. 25
    • Maassab, H.F.1    Cox, N.J.2    Murphy, B.R.3    Kendal, A.P.4
  • 3
    • 0036229655 scopus 로고    scopus 로고
    • Induction of long-term memory CD8(+) T cells for recall of viral clearing responses against influenza virus
    • Deliyannis, G., Jackson, D. C., Ede, N. J. et al. 2002. Induction of long-term memory CD8(+) T cells for recall of viral clearing responses against influenza virus. J. Virol. 76:4212.
    • (2002) J. Virol. , vol.76 , pp. 4212
    • Deliyannis, G.1    Jackson, D.C.2    Ede, N.J.3
  • 4
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun, J. C. and Bevan, M. J. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300:339.
    • (2003) Science , vol.300 , pp. 339
    • Sun, J.C.1    Bevan, M.J.2
  • 5
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 Tcell memory
    • Shedlock, D. J. and Shen, H. 2003. Requirement for CD4 T cell help in generating functional CD8 Tcell memory. Science 300:337.
    • (2003) Science , vol.300 , pp. 337
    • Shedlock, D.J.1    Shen, H.2
  • 7
    • 0033990731 scopus 로고    scopus 로고
    • Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens
    • Zeng, W., Jackson, D. C., Murray, J., Rose, K. and Brown, L. E. 2000. Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens. Vaccine 18:1031.
    • (2000) Vaccine , vol.18 , pp. 1031
    • Zeng, W.1    Jackson, D.C.2    Murray, J.3    Rose, K.4    Brown, L.E.5
  • 8
    • 0036839103 scopus 로고    scopus 로고
    • Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines
    • Zeng, W., Ghosh, S., Lau, Y. F., Brown, L. E. and Jackson, D. C. 2002. Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines. J. Immunol. 169:4905.
    • (2002) J. Immunol. , vol.169 , pp. 4905
    • Zeng, W.1    Ghosh, S.2    Lau, Y.F.3    Brown, L.E.4    Jackson, D.C.5
  • 9
    • 7444271904 scopus 로고    scopus 로고
    • A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses
    • Jackson, D. C., Lau, Y. F., Le, T. et al. 2004. A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses. Proc. Natl Acad. Sci. USA 101:15440.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 15440
    • Jackson, D.C.1    Lau, Y.F.2    Le, T.3
  • 10
    • 0036241804 scopus 로고    scopus 로고
    • Intranasal administration of a synthetic lipopeptide without adjuvant induces systemic immune responses
    • BenMohamed, L., Krishnan, R., Auge, C., Primus, J. F. and Diamond, D. J. 2002. Intranasal administration of a synthetic lipopeptide without adjuvant induces systemic immune responses. Immunology 106:113.
    • (2002) Immunology , vol.106 , pp. 113
    • BenMohamed, L.1    Krishnan, R.2    Auge, C.3    Primus, J.F.4    Diamond, D.J.5
  • 11
    • 24644458684 scopus 로고    scopus 로고
    • Lipid-based self-adjuvanting vaccines
    • Brown, L. E. and Jackson, D. C. 2005. Lipid-based self-adjuvanting vaccines. Curr. Drug Delivery 2:383.
    • (2005) Curr. Drug Delivery , vol.2 , pp. 383
    • Brown, L.E.1    Jackson, D.C.2
  • 12
    • 0036687165 scopus 로고    scopus 로고
    • Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant
    • BenMohamed, L., Belkaid, Y., Loing, E., Brahimi, K., Gras-Masse, H. and Druilhe, P. 2002. Systemic immune responses induced by mucosal administration of lipopeptides without adjuvant. Eur. J. Immunol. 32:2274.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2274
    • BenMohamed, L.1    Belkaid, Y.2    Loing, E.3    Brahimi, K.4    Gras-Masse, H.5    Druilhe, P.6
  • 13
    • 0034649784 scopus 로고    scopus 로고
    • Extension of HLAA*0201-restricted minimal epitope by N epsilon-palmitoyl-lysine increases the life span of functional presentation to cytotoxic T cells
    • Loing, E., Andrieu, M., Thiam, K. et al. 2000. Extension of HLAA*0201-restricted minimal epitope by N epsilon-palmitoyl-lysine increases the life span of functional presentation to cytotoxic T cells. J. Immunol. 164:900.
    • (2000) J. Immunol. , vol.164 , pp. 900
    • Loing, E.1    Andrieu, M.2    Thiam, K.3
  • 14
    • 0037329141 scopus 로고    scopus 로고
    • Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus
    • Chua, B. Y., Healy, A., Cameron, P. U. et al. 2003. Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus. Immunol. Cell Biol. 81:67.
    • (2003) Immunol. Cell Biol. , vol.81 , pp. 67
    • Chua, B.Y.1    Healy, A.2    Cameron, P.U.3
  • 15
    • 9244235974 scopus 로고    scopus 로고
    • Lipopeptide epitopes extended by an Nepsilon-palmitoyl-lysine moiety increase uptake and maturation of dendritic cells through a Toll-like receptor-2 pathway and trigger a Th1-dependent protective immunity
    • Zhu, X., Ramos, T. V., Gras-Masse, H., Kaplan, B. E. and BenMohamed, L. 2004. Lipopeptide epitopes extended by an Nepsilon-palmitoyl-lysine moiety increase uptake and maturation of dendritic cells through a Toll-like receptor-2 pathway and trigger a Th1-dependent protective immunity. Eur. J. Immunol. 34:3102.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 3102
    • Zhu, X.1    Ramos, T.V.2    Gras-Masse, H.3    Kaplan, B.E.4    BenMohamed, L.5
  • 16
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J. and Steinman, R. M. 1998. Dendritic cells and the control of immunity. Nature 392:245.
    • (1998) Nature , vol.392 , pp. 245
    • Banchereau, J.1    Steinman, R.M.2
  • 18
    • 0035865232 scopus 로고    scopus 로고
    • Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2
    • Hertz, C. J., Kiertscher, S. M., Godowski, P. J. et al. 2001. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J. Immunol. 166:2444.
    • (2001) J. Immunol. , vol.166 , pp. 2444
    • Hertz, C.J.1    Kiertscher, S.M.2    Godowski, P.J.3
  • 19
    • 0033618630 scopus 로고    scopus 로고
    • Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
    • Aliprantis, A. O., Yang, R. B., Mark, M. R. et al. 1999. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 285:736.
    • (1999) Science , vol.285 , pp. 736
    • Aliprantis, A.O.1    Yang, R.B.2    Mark, M.R.3
  • 20
    • 0033618562 scopus 로고    scopus 로고
    • Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
    • Brightbill, H. D., Libraty, D. H., Krutzik, S. R. et al. 1999. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 285:732.
    • (1999) Science , vol.285 , pp. 732
    • Brightbill, H.D.1    Libraty, D.H.2    Krutzik, S.R.3
  • 21
    • 0033585011 scopus 로고    scopus 로고
    • Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products
    • Lien, E., Sellati, T. J., Yoshimura, A. et al. 1999. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J. Biol. Chem. 274:33419.
    • (1999) J. Biol. Chem. , vol.274 , pp. 33419
    • Lien, E.1    Sellati, T.J.2    Yoshimura, A.3
  • 22
    • 0023860006 scopus 로고
    • Enhanced recognition of a modified peptide antigen by cytotoxic T cells specific for influenza nucleoprotein
    • Bodmer, H. C., Pemberton, R. M., Rothbard, J. B. and Askonas, B. A. 1988. Enhanced recognition of a modified peptide antigen by cytotoxic T cells specific for influenza nucleoprotein. Cell 52:253.
    • (1988) Cell , vol.52 , pp. 253
    • Bodmer, H.C.1    Pemberton, R.M.2    Rothbard, J.B.3    Askonas, B.A.4
  • 23
    • 0028200153 scopus 로고
    • Conserved determinants for CD4+ T cells within the light chain of the H3 hemagglutinin molecule of influenza virus
    • Jackson, D. C., Drummer, H. E. and Brown, L. E. 1994. Conserved determinants for CD4+ T cells within the light chain of the H3 hemagglutinin molecule of influenza virus. Virology 198:613.
    • (1994) Virology , vol.198 , pp. 613
    • Jackson, D.C.1    Drummer, H.E.2    Brown, L.E.3
  • 24
    • 0032883926 scopus 로고    scopus 로고
    • Preparation and properties of totally synthetic immunogens
    • Jackson, D. C., Fitzmaurice, C. J., Brown, L. E. and Zeng, W. 1999. Preparation and properties of totally synthetic immunogens. Vaccine 18:355.
    • (1999) Vaccine , vol.18 , pp. 355
    • Jackson, D.C.1    Fitzmaurice, C.J.2    Brown, L.E.3    Zeng, W.4
  • 25
    • 0027940262 scopus 로고
    • Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen
    • Zal, T., Volkmann, A. and Stockinger, B. 1994. Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen. J. Exp. Med. 180:2089.
    • (1994) J. Exp. Med. , vol.180 , pp. 2089
    • Zal, T.1    Volkmann, A.2    Stockinger, B.3
  • 26
    • 0021325943 scopus 로고
    • Relative immunogenicity of the cold-adapted influenza virus A/Ann Arbor/6/60 (A/AA/6/60-ca), recombinants of A/AA/6/60-ca, and parental strains with similar surface antigens
    • Tannock, G. A., Paul, J. A. and Barry, R. D. 1984. Relative immunogenicity of the cold-adapted influenza virus A/Ann Arbor/6/60 (A/ AA/6/60-ca), recombinants of A/AA/6/60-ca, and parental strains with similar surface antigens. Infect. Immun. 43:457.
    • (1984) Infect. Immun. , vol.43 , pp. 457
    • Tannock, G.A.1    Paul, J.A.2    Barry, R.D.3
  • 27
    • 0031058029 scopus 로고    scopus 로고
    • Maturation stages of mouse dendritic cells in growth factor-dependent longterm cultures
    • Winzler, C., Rovere, P., Rescigno, M. et al. 1997. Maturation stages of mouse dendritic cells in growth factor-dependent longterm cultures. J. Exp. Med. 185:317.
    • (1997) J. Exp. Med. , vol.185 , pp. 317
    • Winzler, C.1    Rovere, P.2    Rescigno, M.3
  • 28
    • 0018860983 scopus 로고
    • Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens
    • Ozato, K., Mayer, N. and Sachs, D. H. 1980. Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens. J. Immunol. 124:533.
    • (1980) J. Immunol. , vol.124 , pp. 533
    • Ozato, K.1    Mayer, N.2    Sachs, D.H.3
  • 29
    • 0025064577 scopus 로고
    • An analysis of the properties of monoclonal antibodies directed to epitopes on influenza virus hemagglutinin
    • Brown, L. E., Murray, J. M., White, D. O. and Jackson, D. C. 1990. An analysis of the properties of monoclonal antibodies directed to epitopes on influenza virus hemagglutinin. Arch. Virol. 114:1.
    • (1990) Arch. Virol. , vol.114 , pp. 1
    • Brown, L.E.1    Murray, J.M.2    White, D.O.3    Jackson, D.C.4
  • 30
    • 0033861419 scopus 로고    scopus 로고
    • The interleukin-1 receptor/Toll-like receptor superfamily: Signal generators for pro-inflammatory interleukins and microbial products
    • Bowie, A. and O'Neill, L. A. 2000. The interleukin-1 receptor/Toll-like receptor superfamily: Signal generators for pro-inflammatory interleukins and microbial products. J. Leukoc. Biol. 67:508.
    • (2000) J. Leukoc. Biol. , vol.67 , pp. 508
    • Bowie, A.1    O'Neill, L.A.2
  • 31
    • 0035817925 scopus 로고    scopus 로고
    • Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
    • Fitzgerald, K. A., Palsson-McDermott, E. M., Bowie, A. G. et al. 2001. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413:78.
    • (2001) Nature , vol.413 , pp. 78
    • Fitzgerald, K.A.1    Palsson-McDermott, E.M.2    Bowie, A.G.3
  • 32
    • 0028987562 scopus 로고
    • Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice
    • Wysocka, M., Kubin, M., Vieira, L. Q. et al. 1995. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25:672.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 672
    • Wysocka, M.1    Kubin, M.2    Vieira, L.Q.3
  • 33
    • 0022880259 scopus 로고
    • Antigenic determinants of influenza virus hemagglutinin. XII. The epitopes of a synthetic peptide representing the C-terminus of HA1
    • Jackson, D. C., Tang, X. L., Brown, L. E., Murray, J. M., White, D. O. and Tregear, G. W. 1986. Antigenic determinants of influenza virus hemagglutinin. XII. the epitopes of a synthetic peptide representing the C-terminus of HA1. Virology 155:625.
    • (1986) Virology , vol.155 , pp. 625
    • Jackson, D.C.1    Tang, X.L.2    Brown, L.E.3    Murray, J.M.4    White, D.O.5    Tregear, G.W.6
  • 34
    • 0037080026 scopus 로고    scopus 로고
    • Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1
    • Coles, R. M., Mueller, S. N., Heath, W. R., Carbone, F. R. and Brooks, A. G. 2002. Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1. J. Immunol. 168:834.
    • (2002) J. Immunol. , vol.168 , pp. 834
    • Coles, R.M.1    Mueller, S.N.2    Heath, W.R.3    Carbone, F.R.4    Brooks, A.G.5
  • 35
    • 0037018097 scopus 로고    scopus 로고
    • Adjuvants of immunity: Harnessing innate immunity to promote adaptive immunity
    • Bendelac, A. and Medzhitov, R. 2002. Adjuvants of immunity: Harnessing innate immunity to promote adaptive immunity. J. Exp. Med. 195:F19.
    • (2002) J. Exp. Med. , vol.195
    • Bendelac, A.1    Medzhitov, R.2
  • 36
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Poltorak, A., He, X., Smirnova, I. et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 282:2085.
    • (1998) Science , vol.282 , pp. 2085
    • Poltorak, A.1    He, X.2    Smirnova, I.3
  • 37
    • 0033559126 scopus 로고    scopus 로고
    • Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells
    • Curtsinger, J. M., Schmidt, C. S., Mondino, A. et al. 1999. Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells. J. Immunol. 162:3256.
    • (1999) J. Immunol. , vol.162 , pp. 3256
    • Curtsinger, J.M.1    Schmidt, C.S.2    Mondino, A.3
  • 38
    • 0024389666 scopus 로고
    • In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine
    • Deres, K., Schild, H., Wiesmuller, K. H., Jung, G. and Rammensee, H. G. 1989. In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine. Nature 342:561.
    • (1989) Nature , vol.342 , pp. 561
    • Deres, K.1    Schild, H.2    Wiesmuller, K.H.3    Jung, G.4    Rammensee, H.G.5
  • 39
    • 0026471201 scopus 로고
    • Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. Immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein
    • Martinon, F., Gras-Masse, H., Boutillon, C. et al. 1992. Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. Immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein. J. Immunol. 149:3416.
    • (1992) J. Immunol. , vol.149 , pp. 3416
    • Martinon, F.1    Gras-Masse, H.2    Boutillon, C.3
  • 40
    • 0034650420 scopus 로고    scopus 로고
    • Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway
    • Takeuchi, O., Kaufmann, A., Grote, K. et al. 2000. Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway. J. Immunol. 164:554.
    • (2000) J. Immunol. , vol.164 , pp. 554
    • Takeuchi, O.1    Kaufmann, A.2    Grote, K.3
  • 41
    • 0345671672 scopus 로고    scopus 로고
    • Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration
    • Muhlradt, P. F., Kiess, M., Meyer, H., Sussmuth, R. and Jung, G. 1997. Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration. J. Exp. Med. 185:1951.
    • (1997) J. Exp. Med. , vol.185 , pp. 1951
    • Muhlradt, P.F.1    Kiess, M.2    Meyer, H.3    Sussmuth, R.4    Jung, G.5
  • 42
    • 0034610291 scopus 로고    scopus 로고
    • The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
    • Ozinsky, A., Underhill, D. M., Fontenot, J. D. et al. 2000. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc. Natl Acad. Sci. USA 97:13766.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 13766
    • Ozinsky, A.1    Underhill, D.M.2    Fontenot, J.D.3
  • 43
    • 0034922923 scopus 로고    scopus 로고
    • Discrimination of bacterial lipoproteins by Toll-like receptor 6
    • Takeuchi, O., Kawai, T., Muhlradt, P. F. et al. 2001. Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int. Immunol. 13:933.
    • (2001) Int. Immunol. , vol.13 , pp. 933
    • Takeuchi, O.1    Kawai, T.2    Muhlradt, P.F.3
  • 44
    • 0036644042 scopus 로고    scopus 로고
    • Cutting edge: Role of toll-like receptor 1 in mediating immune response to microbial lipoproteins
    • Takeuchi, O., Sato, S., Horiuchi, T. et al. 2002. Cutting edge: Role of toll-like receptor 1 in mediating immune response to microbial lipoproteins. J. Immunol. 169:10.
    • (2002) J. Immunol. , vol.169 , pp. 10
    • Takeuchi, O.1    Sato, S.2    Horiuchi, T.3
  • 45
    • 0041466075 scopus 로고    scopus 로고
    • The ester-bonded palmitoyl side chains of Pam3CysSerLys4 lipopeptide account for its powerful adjuvanticity to HLA class I-restricted CD8+ T lymphocytes
    • Reschner, A., Moretta, A., Landmann, R., Heberer, M., Spagnoli, G. C. and Padovan, E. 2003. The ester-bonded palmitoyl side chains of Pam3CysSerLys4 lipopeptide account for its powerful adjuvanticity to HLA class I-restricted CD8+ T lymphocytes. Eur. J. Immunol. 33:2044.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2044
    • Reschner, A.1    Moretta, A.2    Landmann, R.3    Heberer, M.4    Spagnoli, G.C.5    Padovan, E.6
  • 46
    • 0038759097 scopus 로고    scopus 로고
    • Role of Toll-like receptors in costimulating cytotoxic T cell responses
    • Schwarz, K., Storni, T., Manolova, V. et al. 2003. Role of Toll-like receptors in costimulating cytotoxic T cell responses. Eur. J. Immunol. 33:1465.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1465
    • Schwarz, K.1    Storni, T.2    Manolova, V.3
  • 47
    • 0038545563 scopus 로고    scopus 로고
    • Cutting edge: Link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target J
    • Schjetne, K. W., Thompson, K. M., Nilsen, N. et al. 2003. Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. J. Immunol. 171:32.
    • (2003) Immunol. , vol.171 , pp. 32
    • Schjetne, K.W.1    Thompson, K.M.2    Nilsen, N.3
  • 48
    • 0035190972 scopus 로고    scopus 로고
    • Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein
    • Birchler, T., Seibl, R., Buchner, K. et al. 2001. Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein. Eur. J. Immunol. 31:3131.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3131
    • Birchler, T.1    Seibl, R.2    Buchner, K.3
  • 49
    • 0346366980 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2
    • Hertz, C. J., Wu, Q., Porter, E. M. et al. 2003. Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2. J. Immunol. 171:6820.
    • (2003) J. Immunol. , vol.171 , pp. 6820
    • Hertz, C.J.1    Wu, Q.2    Porter, E.M.3
  • 50
    • 0033569408 scopus 로고    scopus 로고
    • Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6
    • Yang, D., Chertov, O., Bykovskaia, S. N. et al. 1999. Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286:525.
    • (1999) Science , vol.286 , pp. 525
    • Yang, D.1    Chertov, O.2    Bykovskaia, S.N.3
  • 51
    • 0032898451 scopus 로고    scopus 로고
    • A novel mouse beta defensin, Defb2, which is upregulated in the airways by lipopolysaccharide
    • Morrison, G. M., Davidson, D. J. and Dorin, J. R. 1999. A novel mouse beta defensin, Defb2, which is upregulated in the airways by lipopolysaccharide. FEBS Lett 442:112.
    • (1999) FEBS Lett , vol.442 , pp. 112
    • Morrison, G.M.1    Davidson, D.J.2    Dorin, J.R.3


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