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Volumn 12, Issue 2, 2017, Pages 255-273

A complete workflow for high-resolution spectral-stitching nanoelectrospray direct-infusion mass-spectrometry-based metabolomics and lipidomics

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTIC METHOD; ARTICLE; COST BENEFIT ANALYSIS; DATA PROCESSING; DIRECT INFUSION MASS SPECTROMETRY; ELECTROSPRAY; INFORMATION PROCESSING; LIPIDOMICS; MASS SPECTROMETRY; METABOLOMICS; QUALITY CONTROL; REPRODUCIBILITY; SENSITIVITY ANALYSIS; SPECTRAL STITCHING; STATISTICAL ANALYSIS; WORKFLOW; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIPID METABOLISM; NANOTECHNOLOGY; PROCEDURES; TUMOR CELL LINE;

EID: 85010931968     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2016.156     Document Type: Article
Times cited : (113)

References (72)
  • 1
    • 0036007687 scopus 로고    scopus 로고
    • Metabolomics - The link between genotypes and phenotypes
    • Fiehn, O. Metabolomics-the link between genotypes and phenotypes. Plant Mol. Biol. 48, 155-171 (2002).
    • (2002) Plant Mol. Biol. , vol.48 , pp. 155-171
    • Fiehn, O.1
  • 3
    • 18344393519 scopus 로고    scopus 로고
    • Shotgun lipidomics: Electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples
    • Han, X.L. & Gross, R.W. Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples. Mass Spectrom. Rev. 24, 367-412 (2005).
    • (2005) Mass Spectrom. Rev. , vol.24 , pp. 367-412
    • Han, X.L.1    Gross, R.W.2
  • 4
    • 22144478635 scopus 로고    scopus 로고
    • The emerging field of lipidomics
    • Wenk, M.R. The emerging field of lipidomics. Nat. Rev. Drug Discov. 4, 594-610 (2005).
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 594-610
    • Wenk, M.R.1
  • 5
    • 78149356687 scopus 로고    scopus 로고
    • Lipidomics reveals a remarkable diversity of lipids in human plasma
    • Quehenberger, O. et al. Lipidomics reveals a remarkable diversity of lipids in human plasma. J. Lipid Res. 51, 3299-3305 (2010).
    • (2010) J. Lipid Res. , vol.51 , pp. 3299-3305
    • Quehenberger, O.1
  • 6
    • 60149091657 scopus 로고    scopus 로고
    • Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
    • Sreekumar, A. et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature 457, 910-914 (2009).
    • (2009) Nature , vol.457 , pp. 910-914
    • Sreekumar, A.1
  • 7
    • 84941734485 scopus 로고    scopus 로고
    • Drug redeployment to kill leukemia and lymphoma cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids
    • Southam, A.D. et al. Drug redeployment to kill leukemia and lymphoma cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids. Cancer Res. 75, 2530-2540 (2015).
    • (2015) Cancer Res. , vol.75 , pp. 2530-2540
    • Southam, A.D.1
  • 8
    • 0038699591 scopus 로고    scopus 로고
    • High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
    • Allen, J. et al. High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. Nat. Biotechnol. 21, 692-696 (2003).
    • (2003) Nat. Biotechnol. , vol.21 , pp. 692-696
    • Allen, J.1
  • 9
    • 84961288972 scopus 로고    scopus 로고
    • Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein
    • Kamphorst, J.J. et al. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Res. 75, 544-553 (2015).
    • (2015) Cancer Res. , vol.75 , pp. 544-553
    • Kamphorst, J.J.1
  • 10
    • 61849120270 scopus 로고    scopus 로고
    • A new approach to toxicity testing in Daphnia magna: Application of high throughput FT-ICR mass spectrometry metabolomics
    • Taylor, N.S. et al. A new approach to toxicity testing in Daphnia magna: application of high throughput FT-ICR mass spectrometry metabolomics. Metabolomics 5, 44-58 (2009).
    • (2009) Metabolomics , vol.5 , pp. 44-58
    • Taylor, N.S.1
  • 11
    • 79954523476 scopus 로고    scopus 로고
    • Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): Implications for biomonitoring
    • Southam, A.D. et al. Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): implications for biomonitoring. Environ. Sci. Tech. 45, 3759-3767 (2011).
    • (2011) Environ. Sci. Tech. , vol.45 , pp. 3759-3767
    • Southam, A.D.1
  • 12
    • 80052751477 scopus 로고    scopus 로고
    • Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells
    • Gruening, N.-M. et al. Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells. Cell Metab. 14, 415-427 (2011).
    • (2011) Cell Metab. , vol.14 , pp. 415-427
    • Gruening, N.-M.1
  • 13
    • 78149498161 scopus 로고    scopus 로고
    • Extensive in vivo metabolite-protein interactions revealed by large-scale systematic analyses
    • Li, X., Gianoulis, T.A., Yip, K.Y., Gerstein, M. & Snyder, M. Extensive in vivo metabolite-protein interactions revealed by large-scale systematic analyses. Cell 143, 639-650 (2010).
    • (2010) Cell , vol.143 , pp. 639-650
    • Li, X.1    Gianoulis, T.A.2    Yip, K.Y.3    Gerstein, M.4    Snyder, M.5
  • 14
    • 84875755814 scopus 로고    scopus 로고
    • Influence of metabolism on epigenetics and disease
    • Kaelin, W.G. Jr. & McKnight, S.L. Influence of metabolism on epigenetics and disease. Cell 153, 56-69 (2013).
    • (2013) Cell , vol.153 , pp. 56-69
    • Kaelin, W.G.1    McKnight, S.L.2
  • 15
    • 18844406001 scopus 로고    scopus 로고
    • Measuring the metabolome: Current analytical technologies
    • Dunn, W.B., Bailey, N.J.C. & Johnson, H.E. Measuring the metabolome: current analytical technologies. Analyst 130, 606-625 (2005).
    • (2005) Analyst , vol.130 , pp. 606-625
    • Dunn, W.B.1    Bailey, N.J.C.2    Johnson, H.E.3
  • 16
    • 27744479716 scopus 로고    scopus 로고
    • The expanding role of mass spectrometry in metabolite profiling and characterization
    • Want, E.J., Cravatt, B.F. & Siuzdak, G. The expanding role of mass spectrometry in metabolite profiling and characterization. Chembiochem 6, 1941-1951 (2005).
    • (2005) Chembiochem , vol.6 , pp. 1941-1951
    • Want, E.J.1    Cravatt, B.F.2    Siuzdak, G.3
  • 17
    • 24644481093 scopus 로고    scopus 로고
    • High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses
    • Jonsson, P. et al. High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses. Anal. Chem. 77, 5635-5642 (2005).
    • (2005) Anal. Chem. , vol.77 , pp. 5635-5642
    • Jonsson, P.1
  • 18
    • 41149178478 scopus 로고    scopus 로고
    • LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics
    • Theodoridis, G., Gika, H.G. & Wilson, I.D. LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics. Trac-Trends Anal. Chem. 27, 251-260 (2008).
    • (2008) Trac-Trends Anal. Chem. , vol.27 , pp. 251-260
    • Theodoridis, G.1    Gika, H.G.2    Wilson, I.D.3
  • 19
    • 84871941512 scopus 로고    scopus 로고
    • CE-MS for metabolomics: Developments and applications in the period 2010-2012
    • Ramautar, R., Somsen, G.W. & de Jong, G.J. CE-MS for metabolomics: developments and applications in the period 2010-2012. Electrophoresis 34, 86-98 (2013).
    • (2013) Electrophoresis , vol.34 , pp. 86-98
    • Ramautar, R.1    Somsen, G.W.2    De Jong, G.J.3
  • 20
    • 66149192291 scopus 로고    scopus 로고
    • High-resolution extracted ion chromatography, a new tool for metabolomics and lipidomics using a second-generation orbitrap mass spectrometer
    • Koulman, A. et al. High-resolution extracted ion chromatography, a new tool for metabolomics and lipidomics using a second-generation orbitrap mass spectrometer. Rapid Commun. Mass Spectrom. 23, 1411-1418 (2009).
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , pp. 1411-1418
    • Koulman, A.1
  • 21
    • 0037371728 scopus 로고    scopus 로고
    • An optimized protocol for metabolome analysis in yeast using direct infusion electrospray mass spectrometry
    • Castrillo, J.I., Hayes, A., Mohammed, S., Gaskell, S.J. & Oliver, S.G. An optimized protocol for metabolome analysis in yeast using direct infusion electrospray mass spectrometry. Phytochemistry 62, 929-937 (2003).
    • (2003) Phytochemistry , vol.62 , pp. 929-937
    • Castrillo, J.I.1    Hayes, A.2    Mohammed, S.3    Gaskell, S.J.4    Oliver, S.G.5
  • 22
    • 40649099178 scopus 로고    scopus 로고
    • High-throughput nontargeted metabolite fingerprinting using nominal mass flow injection electrospray mass spectrometry
    • Beckmann, M., Parker, D., Enot, D.P., Duval, E. & Draper, J. High-throughput, nontargeted metabolite fingerprinting using nominal mass flow injection electrospray mass spectrometry. Nat. Protoc. 3, 486-504 (2008).
    • (2008) Nat. Protoc. , vol.3 , pp. 486-504
    • Beckmann, M.1    Parker, D.2    Enot, D.P.3    Duval, E.4    Draper, J.5
  • 23
    • 34347229424 scopus 로고    scopus 로고
    • Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method
    • Southam, A.D., Payne, T.G., Cooper, H.J., Arvanitis, T.N. & Viant, M.R. Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method. Anal. Chem. 79, 4595-4602 (2007).
    • (2007) Anal. Chem. , vol.79 , pp. 4595-4602
    • Southam, A.D.1    Payne, T.G.2    Cooper, H.J.3    Arvanitis, T.N.4    Viant, M.R.5
  • 24
    • 79956129310 scopus 로고    scopus 로고
    • Characterization of isotopic abundance measurements in high resolution FT-ICR and Orbitrap mass spectra for improved confidence of metabolite identification
    • Weber, R.J.M., Southam, A.D., Sommer, U. & Viant, M.R. Characterization of isotopic abundance measurements in high resolution FT-ICR and Orbitrap mass spectra for improved confidence of metabolite identification. Anal. Chem. 83, 3737-3743 (2011).
    • (2011) Anal. Chem. , vol.83 , pp. 3737-3743
    • Weber, R.J.M.1    Southam, A.D.2    Sommer, U.3    Viant, M.R.4
  • 25
    • 27544478275 scopus 로고    scopus 로고
    • Uniformity of ionization response of structurally diverse analytes using a chip-based nanoelectrospray ionization source
    • Hop, C., Chen, Y. & Yu, L.J. Uniformity of ionization response of structurally diverse analytes using a chip-based nanoelectrospray ionization source. Rapid Commun. Mass Spectrom. 19, 3139-3142 (2005).
    • (2005) Rapid Commun. Mass Spectrom. , vol.19 , pp. 3139-3142
    • Hop, C.1    Chen, Y.2    Yu, L.J.3
  • 26
    • 33646754900 scopus 로고    scopus 로고
    • Metabolomic database annotations via query of elemental compositions: Mass accuracy is insufficient even at less than 1 ppm
    • Kind, T. & Fiehn, O. Metabolomic database annotations via query of elemental compositions: Mass accuracy is insufficient even at less than 1 ppm. BMC Bioinformatics 7, 234 (2006).
    • (2006) BMC Bioinformatics , vol.7 , pp. 234
    • Kind, T.1    Fiehn, O.2
  • 27
    • 34748888866 scopus 로고    scopus 로고
    • Proposed minimum reporting standards for chemical analysis
    • Sumner, L.W. et al. Proposed minimum reporting standards for chemical analysis. Metabolomics 3, 211-221 (2007).
    • (2007) Metabolomics , vol.3 , pp. 211-221
    • Sumner, L.W.1
  • 28
    • 84991526698 scopus 로고    scopus 로고
    • Galaxy-M: A Galaxy workflow for processing and analysing direct infusion and liquid chromatography mass spectrometry-based metabolomics data
    • Davidson, R.L., Weber, R.J.M., Liu, H., Sharma-Oates, A. & Viant, M.R. Galaxy-M: a Galaxy workflow for processing and analysing direct infusion and liquid chromatography mass spectrometry-based metabolomics data. Gigascience 5, 10 (2015).
    • (2015) Gigascience , vol.5 , pp. 10
    • Davidson, R.L.1    Weber, R.J.M.2    Liu, H.3    Sharma-Oates, A.4    Viant, M.R.5
  • 29
    • 84941263818 scopus 로고    scopus 로고
    • Direct infusion mass spectrometry metabolomics dataset: A benchmark for data processing and quality control
    • Kirwan, J.A., Weber, R.J.M., Broadhurst, D.I. & Viant, M.R. Direct infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control. Sci. Data 1, 140012 (2014).
    • (2014) Sci. Data , vol.1 , pp. 140012
    • Kirwan, J.A.1    Weber, R.J.M.2    Broadhurst, D.I.3    Viant, M.R.4
  • 30
    • 84959498006 scopus 로고    scopus 로고
    • Statistical correlations between NMR spectroscopy and direct infusion FT-ICR mass spectrometry aid annotation of unknowns in metabolomics
    • Hao, J. et al. Statistical correlations between NMR spectroscopy and direct infusion FT-ICR mass spectrometry aid annotation of unknowns in metabolomics. Anal. Chem. 88, 2583-2589 (2016).
    • (2016) Anal. Chem. , vol.88 , pp. 2583-2589
    • Hao, J.1
  • 31
    • 77958062885 scopus 로고    scopus 로고
    • Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer
    • Lin, L. et al. Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer. Analyst 135, 2970-2978 (2010).
    • (2010) Analyst , vol.135 , pp. 2970-2978
    • Lin, L.1
  • 32
    • 0038574979 scopus 로고    scopus 로고
    • Ion suppression in mass spectrometry
    • Annesley, T.M. Ion suppression in mass spectrometry. Clin. Chem. 49, 1041-1044 (2003).
    • (2003) Clin. Chem. , vol.49 , pp. 1041-1044
    • Annesley, T.M.1
  • 33
    • 0037487098 scopus 로고    scopus 로고
    • Effect of different solution flow rates on analyte ion signals in nano-ESI MS, or: When does ESI turn into nano-ESI?
    • Schmidt, A., Karas, M. & Dulcks, T. Effect of different solution flow rates on analyte ion signals in nano-ESI MS, or: when does ESI turn into nano-ESI? J. Am. Soc. Mass Spectrom. 14, 492-500 (2003).
    • (2003) J. Am. Soc. Mass Spectrom. , vol.14 , pp. 492-500
    • Schmidt, A.1    Karas, M.2    Dulcks, T.3
  • 34
    • 84873414589 scopus 로고    scopus 로고
    • Accurate quantification of lipid species by electrospray ionization mass spectrometry-meets a key challenge in lipidomics
    • Yang, K. & Han, X. Accurate quantification of lipid species by electrospray ionization mass spectrometry-meets a key challenge in lipidomics. Metabolites 1, 21-40 (2011).
    • (2011) Metabolites , vol.1 , pp. 21-40
    • Yang, K.1    Han, X.2
  • 35
    • 79954515824 scopus 로고    scopus 로고
    • Metabolomics of microliter hemolymph samples enables an improved understanding of the combined metabolic and transcriptional responses of Daphnia magna to cadmium
    • Poynton, H.C. et al. Metabolomics of microliter hemolymph samples enables an improved understanding of the combined metabolic and transcriptional responses of Daphnia magna to cadmium. Environ. Sci. Tech. 45, 3710-3717 (2011).
    • (2011) Environ. Sci. Tech. , vol.45 , pp. 3710-3717
    • Poynton, H.C.1
  • 37
    • 84940792523 scopus 로고    scopus 로고
    • Prediction of classical clinical chemistry parameters using a direct infusion mass spectrometry
    • Lokhov, P.G. et al. Prediction of classical clinical chemistry parameters using a direct infusion mass spectrometry. International Journal of Mass Spectrometry http://dx.doi.org/10.1016/j.ijms.2015.08.006 (2015).
    • (2015) International Journal of Mass Spectrometry
    • Lokhov, P.G.1
  • 38
    • 84928184320 scopus 로고    scopus 로고
    • The effect of perhexiline on myocardial protection during coronary artery surgery: A two-centre, randomized, double-blind, placebo-controlled trial
    • Drury, N.E. et al. The effect of perhexiline on myocardial protection during coronary artery surgery: a two-centre, randomized, double-blind, placebo-controlled trial. Eur. J. Cardio-Thorac. Surg. 47, 464-472 (2015).
    • (2015) Eur. J. Cardio-Thorac. Surg. , vol.47 , pp. 464-472
    • Drury, N.E.1
  • 39
    • 84879339018 scopus 로고    scopus 로고
    • Disruption of DNA methylation via S-adenosylhomocysteine is a key process in high incidence liver carcinogenesis in fish
    • Mirbahai, L. et al. Disruption of DNA methylation via S-adenosylhomocysteine is a key process in high incidence liver carcinogenesis in fish. J. Proteome Res. 12, 2895-2904 (2013).
    • (2013) J. Proteome Res. , vol.12 , pp. 2895-2904
    • Mirbahai, L.1
  • 40
    • 84889258885 scopus 로고    scopus 로고
    • A stable-isotope mass spectrometry-based metabolic footprinting approach to analyze exudates from phytoplankton
    • Weber, R.J.M., Selander, E., Sommer, U. & Viant, M.R. A stable-isotope mass spectrometry-based metabolic footprinting approach to analyze exudates from phytoplankton. Mar. Drugs 11, 4158-4175 (2013).
    • (2013) Mar. Drugs , vol.11 , pp. 4158-4175
    • Weber, R.J.M.1    Selander, E.2    Sommer, U.3    Viant, M.R.4
  • 41
    • 84919950718 scopus 로고    scopus 로고
    • Distinguishing between the metabolome and xenobiotic exposome in environmental field samples analysed by direct-infusion mass spectrometry based metabolomics and lipidomics
    • Southam, A.D. et al. Distinguishing between the metabolome and xenobiotic exposome in environmental field samples analysed by direct-infusion mass spectrometry based metabolomics and lipidomics. Metabolomics 10, 1050-1058 (2014).
    • (2014) Metabolomics , vol.10 , pp. 1050-1058
    • Southam, A.D.1
  • 42
    • 84896366331 scopus 로고    scopus 로고
    • Systems toxicology: From basic research to risk assessment
    • Sturla, S.J. et al. Systems toxicology: from basic research to risk assessment. Chem. Res. Toxicol. 27, 314-329 (2014).
    • (2014) Chem. Res. Toxicol. , vol.27 , pp. 314-329
    • Sturla, S.J.1
  • 43
    • 77149124246 scopus 로고    scopus 로고
    • Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: Hurdles, achievements, and future outlook
    • Van Aggelen, G. et al. Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: hurdles, achievements, and future outlook. Environ. Health Perspect. 118, 1-5 (2010).
    • (2010) Environ. Health Perspect. , vol.118 , pp. 1-5
    • Van Aggelen, G.1
  • 44
    • 60649117985 scopus 로고    scopus 로고
    • Spectral relative standard deviation: A practical benchmark in metabolomics
    • Parsons, H.M., Ekman, D.R., Collette, T.W. & Viant, M.R. Spectral relative standard deviation: a practical benchmark in metabolomics. Analyst 134, 478-485 (2009).
    • (2009) Analyst , vol.134 , pp. 478-485
    • Parsons, H.M.1    Ekman, D.R.2    Collette, T.W.3    Viant, M.R.4
  • 45
    • 84555189650 scopus 로고    scopus 로고
    • Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling
    • Sellick, C.A., Hansen, R., Stephens, G.M., Goodacre, R. & Dickson, A.J. Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling. Nat. Protoc. 6, 1241-1249 (2011).
    • (2011) Nat. Protoc. , vol.6 , pp. 1241-1249
    • Sellick, C.A.1    Hansen, R.2    Stephens, G.M.3    Goodacre, R.4    Dickson, A.J.5
  • 46
    • 77958485622 scopus 로고    scopus 로고
    • Discriminating between different acute chemical toxicities via changes in the Daphnid metabolome
    • Taylor, N.S., Weber, R.J.M., White, T.A. & Viant, M.R. Discriminating between different acute chemical toxicities via changes in the Daphnid metabolome. Toxicol. Sci. 118, 307-317 (2010).
    • (2010) Toxicol. Sci. , vol.118 , pp. 307-317
    • Taylor, N.S.1    Weber, R.J.M.2    White, T.A.3    Viant, M.R.4
  • 47
    • 84872039962 scopus 로고    scopus 로고
    • Global metabolic profiling of animal and human tissues via UPLC-MS
    • Want, E.J. et al. Global metabolic profiling of animal and human tissues via UPLC-MS. Nat. Protoc. 8, 17-32 (2013).
    • (2013) Nat. Protoc. , vol.8 , pp. 17-32
    • Want, E.J.1
  • 48
    • 77952205557 scopus 로고    scopus 로고
    • Global metabolic profiling procedures for urine using UPLC-MS
    • Want, E.J. et al. Global metabolic profiling procedures for urine using UPLC-MS. Nat. Protoc. 5, 1005-1018 (2010).
    • (2010) Nat. Protoc. , vol.5 , pp. 1005-1018
    • Want, E.J.1
  • 49
    • 79959913950 scopus 로고    scopus 로고
    • Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
    • Dunn, W.B. et al. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat. Protoc. 6, 1060-1083 (2011).
    • (2011) Nat. Protoc. , vol.6 , pp. 1060-1083
    • Dunn, W.B.1
  • 50
    • 36148989929 scopus 로고    scopus 로고
    • High-throughput tissue extraction protocol for NMR-and MS-based metabolomics
    • Wu, H., Southam, A.D., Hines, A. & Viant, M.R. High-throughput tissue extraction protocol for NMR-and MS-based metabolomics. Anal. Biochem. 372, 204-212 (2008).
    • (2008) Anal. Biochem. , vol.372 , pp. 204-212
    • Wu, H.1    Southam, A.D.2    Hines, A.3    Viant, M.R.4
  • 51
    • 33947427846 scopus 로고    scopus 로고
    • Evaluation of metabolite extraction strategies from tissue samples using NMR metabolomics
    • Lin, C.Y., Wu, H.F., Tjeerdema, R.S. & Viant, M.R. Evaluation of metabolite extraction strategies from tissue samples using NMR metabolomics. Metabolomics 3, 55-67 (2007).
    • (2007) Metabolomics , vol.3 , pp. 55-67
    • Lin, C.Y.1    Wu, H.F.2    Tjeerdema, R.S.3    Viant, M.R.4
  • 52
    • 84155172923 scopus 로고    scopus 로고
    • Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses
    • Han, X., Yang, K. & Gross, R.W. Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses. Mass Spectrome. Rev. 31, 134-178 (2012).
    • (2012) Mass Spectrome. Rev. , vol.31 , pp. 134-178
    • Han, X.1    Yang, K.2    Gross, R.W.3
  • 53
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E.G. & Dyer, W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917 (1959).
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 54
  • 55
    • 0034282498 scopus 로고    scopus 로고
    • A fully integrated monolithic microchip electrospray device for mass spectrometry
    • Schultz, G.A., Corso, T.N., Prosser, S.J. & Zhang, S. A fully integrated monolithic microchip electrospray device for mass spectrometry. Anal. Chem. 72, 4058-4063 (2000).
    • (2000) Anal. Chem. , vol.72 , pp. 4058-4063
    • Schultz, G.A.1    Corso, T.N.2    Prosser, S.J.3    Zhang, S.4
  • 56
    • 14744267430 scopus 로고    scopus 로고
    • Accurate mass measurements by Fourier transform mass spectrometry
    • Zhang, L.K., Rempel, D., Pramanik, B.N. & Gross, M.L. Accurate mass measurements by Fourier transform mass spectrometry. Mass Spectrom. Rev. 24, 286-309 (2005).
    • (2005) Mass Spectrom. Rev. , vol.24 , pp. 286-309
    • Zhang, L.K.1    Rempel, D.2    Pramanik, B.N.3    Gross, M.L.4
  • 57
    • 65549121144 scopus 로고    scopus 로고
    • A signal filtering method for improved quantification and noise discrimination in Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics data
    • Payne, T.G., Southam, A.D., Arvanitis, T.N. & Viant, M.R. A signal filtering method for improved quantification and noise discrimination in Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics data. J. Am. Soc. Mass Spectrom. 20, 1087-1095 (2009).
    • (2009) J. Am. Soc. Mass Spectrom. , vol.20 , pp. 1087-1095
    • Payne, T.G.1    Southam, A.D.2    Arvanitis, T.N.3    Viant, M.R.4
  • 58
    • 33745728718 scopus 로고    scopus 로고
    • Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in H-1 NMR metabonomics
    • Dieterle, F., Ross, A., Schlotterbeck, G. & Senn, H. Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in H-1 NMR metabonomics. Anal. Chem. 78, 4281-4290 (2006).
    • (2006) Anal. Chem. , vol.78 , pp. 4281-4290
    • Dieterle, F.1    Ross, A.2    Schlotterbeck, G.3    Senn, H.4
  • 59
    • 84878275118 scopus 로고    scopus 로고
    • Characterising and correcting batch variation in an automated direct infusion mass spectrometry (DIMS) metabolomics workflow
    • Kirwan, J.A., Broadhurst, D.I., Davidson, R.L. & Viant, M.R. Characterising and correcting batch variation in an automated direct infusion mass spectrometry (DIMS) metabolomics workflow. Anal. Bioanal. Chem. 405, 5147-5157 (2013).
    • (2013) Anal. Bioanal. Chem. , vol.405 , pp. 5147-5157
    • Kirwan, J.A.1    Broadhurst, D.I.2    Davidson, R.L.3    Viant, M.R.4
  • 60
    • 84860380628 scopus 로고    scopus 로고
    • Missing values in mass spectrometry based metabolomics: An undervalued step in the data processing pipeline
    • Hrydziuszko, O. & Viant, M.R. Missing values in mass spectrometry based metabolomics: an undervalued step in the data processing pipeline. Metabolomics 8, S161-S174 (2012).
    • (2012) Metabolomics , vol.8 , pp. S161-S174
    • Hrydziuszko, O.1    Viant, M.R.2
  • 61
    • 34548490763 scopus 로고    scopus 로고
    • Improved classification accuracy in 1-and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation
    • Parsons, H.M., Ludwig, C., Gunther, U.L. & Viant, M.R. Improved classification accuracy in 1-and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation. BMC Bioinformatics 8, 16 (2007).
    • (2007) BMC Bioinformatics , vol.8 , pp. 16
    • Parsons, H.M.1    Ludwig, C.2    Gunther, U.L.3    Viant, M.R.4
  • 62
    • 33747019547 scopus 로고    scopus 로고
    • Centering, scaling, and transformations: Improving the biological information content of metabolomics data
    • van den Berg, R.A., Hoefsloot, H.C.J., Westerhuis, J.A., Smilde, A.K. & van der Werf, M.J. Centering, scaling, and transformations: improving the biological information content of metabolomics data. BMC Genomics 7, 142 (2006).
    • (2006) BMC Genomics , vol.7 , pp. 142
    • Van Den Berg, R.A.1    Hoefsloot, H.C.J.2    Westerhuis, J.A.3    Smilde, A.K.4    Van Der Werf, M.J.5
  • 63
    • 85010963968 scopus 로고
    • Controlling the false discovery rate - A practical and powerful approach to multiple testing
    • Benjamini, Y. & Hochberg, Y. Controlling the false discovery rate-a practical and powerful approach to multiple testing. J. R. Stat. Soc. B 57, 289-300 (1995).
    • (1995) J. R. Stat. Soc. B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 65
    • 84860386341 scopus 로고    scopus 로고
    • Double-check: Validation of diagnostic statistics for PLS-DA models in metabolomics studies
    • Szymanska, E., Saccenti, E., Smilde, A.K. & Westerhuis, J.A. Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies. Metabolomics 8, 3-16 (2012).
    • (2012) Metabolomics , vol.8 , pp. 3-16
    • Szymanska, E.1    Saccenti, E.2    Smilde, A.K.3    Westerhuis, J.A.4
  • 66
    • 84874345577 scopus 로고    scopus 로고
    • Mass appeal: Metabolite identification in mass spectrometry-focused untargeted metabolomics
    • Dunn, W.B. et al. Mass appeal: metabolite identification in mass spectrometry-focused untargeted metabolomics. Metabolomics 9, S44-S66 (2013).
    • (2013) Metabolomics , vol.9 , pp. S44-S66
    • Dunn, W.B.1
  • 67
    • 77958506191 scopus 로고    scopus 로고
    • MI-Pack: Increased confidence of metabolite identification in mass spectra by integrating accurate masses and metabolic pathways
    • Weber, R.J.M. & Viant, M.R. MI-Pack: increased confidence of metabolite identification in mass spectra by integrating accurate masses and metabolic pathways. Chemometrics Intell. Lab. Syst. 104, 75-82 (2010).
    • (2010) Chemometrics Intell. Lab. Syst. , vol.104 , pp. 75-82
    • Weber, R.J.M.1    Viant, M.R.2
  • 68
    • 34247163207 scopus 로고    scopus 로고
    • Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry
    • Kind, T. & Fiehn, O. Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry. BMC Bioinformatics 8, 105 (2007).
    • (2007) BMC Bioinformatics , vol.8 , pp. 105
    • Kind, T.1    Fiehn, O.2
  • 69
    • 84876560030 scopus 로고    scopus 로고
    • MetaboLights-an open-access general-purpose repository for metabolomics studies and associated meta-data
    • Haug, K. et al. MetaboLights-an open-access general-purpose repository for metabolomics studies and associated meta-data. Nucleic Acids Res. 41, D781-D786 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D781-D786
    • Haug, K.1
  • 70
    • 84976887093 scopus 로고    scopus 로고
    • Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools
    • Sud, M. et al. Metabolomics Workbench: an international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools. Nucleic Acids Res. 44, D463-D470 (2015).
    • (2015) Nucleic Acids Res. , vol.44 , pp. D463-D470
    • Sud, M.1
  • 71
    • 50349092811 scopus 로고    scopus 로고
    • Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach
    • Bennett, B.D., Yuan, J., Kimball, E.H. & Rabinowitz, J.D. Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach. Nat. Protoc. 3, 1299-1311 (2008).
    • (2008) Nat. Protoc. , vol.3 , pp. 1299-1311
    • Bennett, B.D.1    Yuan, J.2    Kimball, E.H.3    Rabinowitz, J.D.4
  • 72
    • 84976232096 scopus 로고    scopus 로고
    • Metabolomics confirms that dissolved organic carbon mitigates copper toxicity
    • Taylor, N.S. et al. Metabolomics confirms that dissolved organic carbon mitigates copper toxicity. Environ. Toxicol. Chem. 35, 635-644 (2015).
    • (2015) Environ. Toxicol. Chem. , vol.35 , pp. 635-644
    • Taylor, N.S.1


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