Determination of Glucose Utilization Rates in Cultured Astrocytes and Neurons with [14C]deoxyglucose: Progress, Pitfalls, and Discovery of Intracellular Glucose Compartmentation

Neurochemical Research

Volumn 42, Issue 1, 2017, Pages 50-63

  Dienel, Gerald A ^a,b   Cruz, Nancy F ^a   Sokoloff, Louis ^a   Driscoll, Bernard F ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Astrocyte; Compartmentation; Deoxyglucose; Glucose; Lumped constant; Neuron

Indexed keywords

2 (N (7 NITROBENZ 2 OXA 1,3 DIAZOL 4 YL)AMINO) 2 DEOXYGLUCOSE; FLUORESCENT DYE; GLUCOSE; HEXOKINASE; HEXOSE; UNCLASSIFIED DRUG; CARBON; DEOXYGLUCOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE CULTURE; BRAIN TISSUE; DRUG METABOLISM; DRUG TRANSPORT; ENZYME ACTIVITY; FEMALE; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; HYPOGLYCEMIA; METABOLIC RATE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; STEADY STATE; ANIMAL; ASTROCYTE; BRAIN; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; INTRACELLULAR FLUID; METABOLISM; NERVE CELL; PHYSIOLOGY; PREGNANCY; SPRAGUE DAWLEY RAT; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ASTROCYTES; BIOLOGICAL TRANSPORT; BRAIN; CARBON RADIOISOTOPES; CELLS, CULTURED; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUCOSE; INTRACELLULAR FLUID; NEURONS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 85010930820     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-015-1650-x     Document Type: Article

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