Susceptibility to chronic inflammation: an update

Archives of Toxicology

Volumn 91, Issue 3, 2017, Pages 1131-1141

  Nasef, Noha Ahmed ^a   Mehta, Sunali ^a,b   Ferguson, Lynnette R ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Chronic inflammation; Cytokines; Diet; Immunity; Infection; Stress

Indexed keywords

CHEMOKINE; CYTOKINE;

CHRONIC INFLAMMATION; DIET; DISEASE COURSE; DISEASE PREDISPOSITION; ENVIRONMENTAL EXPOSURE; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; HUMAN; PRIORITY JOURNAL; REVIEW; STRESS; ADVERSE EFFECTS; CHRONIC DISEASE; COMPLICATION; GENETICS; INFECTION; INFLAMMATION; MENTAL STRESS; METABOLISM;

CHRONIC DISEASE; CYTOKINES; DIET; ENVIRONMENTAL EXPOSURE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFECTION; INFLAMMATION; STRESS, PSYCHOLOGICAL;

EID: 85010831582     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-016-1914-5     Document Type: Review

References (114)

1. Ahluwalia N, Andreeva V, Kesse-Guyot E, Hercberg S (2013) Dietary patterns, inflammation and the metabolic syndrome. Diabetes Metab 39(2):99–110
2. Akbaraly TN, Shipley MJ, Ferrie JE et al (2015) Long-term adherence to healthy dietary guidelines and chronic inflammation in the prospective Whitehall II study. Am J Med 128(2):152–160. e4
3. Antoni M, Lutgendorf S, Blomberg B et al (2012) Transcriptional modulation of human leukocytes by cognitive-behavioral stress management in women undergoing treatment for breast cancer. Biol Psychiatry 71(4):366–372
4. Assa A, Vong L, Pinnell LJ, Avitzur N, Johnson‐Henry KC, Sherman PM (2014) Vitamin D deficiency promotes epithelial barrier dysfunction and intestinal inflammation. J Infect Dis 210(8):1296–1305
5. Ataie-Kachoie P, Pourgholami MH, Morris DL (2013) Inhibition of the IL-6 signaling pathway: a strategy to combat chronic inflammatory diseases and cancer. Cytokine Growth Factor Rev 24(2):163–173
6. Azevedo PM, Merriman TR, Topless RK, Wilson NJ, Crengle S, Lennon DR (2016) Association study involving polymorphisms in IL-6, IL-1RA, and CTLA4 genes and rheumatic heart disease in New Zealand population of Māori and Pacific ancestry. Cytokine 85:201–206
7. + T cell responses to influenza. Nat Immunol 11(3):216–224
8. Baraliakos X, Borah B, Braun J et al (2016) Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study. Ann Rheum Dis 75(2):408–412
9. Beringer A, Noack M, Miossec P (2016) IL-17 in chronic inflammation: from discovery to targeting. Trends Mol Med 22(3):230–241
10. Bhattacharjee S, Rajaraman P, Jacobs KB et al (2012) A subset-based approach improves power and interpretation for the combined analysis of genetic association studies of heterogeneous traits. Am J Hum Genet 90(5):821–835
11. Bosschaerts T, Guilliams M, Stijlemans B et al (2010) Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-γ and MyD88 signaling. PLoS Pathog 6(8):e1001045
12. Brenchley JM, Price DA, Schacker TW et al (2006) Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 12(12):1365–1371
13. Buckley T, Mihailidou AS, Bartrop R et al (2011) Haemodynamic changes during early bereavement: potential contribution to increased cardiovascular risk. Heart Lung Circ 20(2):91–98
14. Buraczynska M, Zukowski P, Drop B, Baranowicz-Gaszczyk I, Ksiazek A (2016) Effect of G (-174) C polymorphism in interleukin-6 gene on cardiovascular disease in type 2 diabetes patients. Cytokine 79:7–11
15. Calder P (2013) Inflammation: an introduction nutrition and physical activity in inflammatory diseases CAB International. Oxfordshire, UK, pp 1–22
16. Campbell IK, van Nieuwenhuijze A, Segura E et al (2011) Differentiation of inflammatory dendritic cells is mediated by NF-κB1–dependent GM-CSF production in CD4 T cells. J Immunol 186(9):5468–5477
17. Campbell AM, Kashgarian M, Shlomchik MJ (2012) NADPH oxidase inhibits the pathogenesis of systemic lupus erythematosus. Sci Transl Med 4(157):157ra141
18. Canna SW, De Jesus AA, Gouni S et al (2014) An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome. Nat Genet 46(10):1140–1146
19. Carlberg C, Ulven SM, Molnár F (2016) Chronic inflammation and metabolic stress nutrigenomics. Springer, Heidelberg, pp 121–137
20. Cătană C-S, Berindan Neagoe I, Cozma V, Magdaş C, Tăbăran F, Dumitraşcu DL (2015) Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease. World J Gastroenterol 21(19):5823–5830
21. Choy EH, Kavanaugh AF, Jones SA (2013) The problem of choice: current biologic agents and future prospects in RA. Nat Rev Rheumatol 9(3):154–163
22. Cole SW, Conti G, Arevalo JM, Ruggiero AM, Heckman JJ, Suomi SJ (2012) Transcriptional modulation of the developing immune system by early life social adversity. Proc Natl Acad Sci 109(50):20578–20583
23. Cooks T, Pateras IS, Tarcic O et al (2013) Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer. Cancer Cell 23(5):634–646
24. Cui W et al (2016) Vitamin A deficiency promotes inflammation by induction of type 2 cytokines in experimental ovalbumin‐induced asthma murine model. Inflammation 39:1798–1804
25. Cummins EP, Keogh CE, Crean D, Taylor CT (2016) The role of HIF in immunity and inflammation. Mol Asp Med 47:24–34
26. De Trez C, Magez S, Akira S, Ryffel B, Carlier Y, Muraille E (2009) iNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant mice. PLoS Pathog 5(6):e1000494
27. Deeks SG, Tracy R, Douek DC (2013) Systemic effects of inflammation on health during chronic HIV infection. Immunity 39(4):633–645
28. Dresing P, Borkens S, Kocur M, Kropp S, Scheu S (2010) A fluorescence reporter model defines “Tip-DCs” as the cellular source of interferon β in murine listeriosis. PLoS ONE 5(12):e15567
29. Ellinghaus D, Jostins L, Spain SL, et al (2016) Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nat Genet 48(5):510–518
30. Eltzschig HK, Bratton DL, Colgan SP (2014) Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases. Nat Rev Drug Discov 13(11):852–869
31. Esmaillzadeh A, Kimiagar M, Mehrabi Y, Azadbakht L, Hu FB, Willett WC (2007) Dietary patterns and markers of systemic inflammation among Iranian women. J Nutr 137(4):992–998
32. Fei M, Bhatia S, Oriss TB et al (2011) TNF-α from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection. Proc Natl Acad Sci 108(13):5360–5365
33. Ferguson LR (2010) Chronic inflammation and mutagenesis. Mutat Res, Fundam Mol Mech Mutagen 690(1):3–11
34. Fossiez F, Djossou O, Chomarat P et al (1996) T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med 183(6):2593–2603
35. Franceschi C, Campisi J (2014) Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. J Gerontol Ser A Biol Sci Med Sci 69(Suppl 1):S4–S9
36. Freiberg MS, Chang C-CH, Kuller LH et al (2013) HIV infection and the risk of acute myocardial infarction. Jama Intern Med 173(8):614–622
37. + T cells. J Infect Dis 200(8):1212–1215
38. Gibson R et al (2014) Tissue iron deficiency and adiposity‐related inflammation in disadvantaged preschoolers from NE Brazil. Eur J Clin Nutr 68:887–891
39. Grant SF, Qu H-Q, Bradfield JP et al (2009) Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes. Diabetes 58(1):290–295
40. Hancock RE, Haney EF, Gill EE (2016) The immunology of host defence peptides: beyond antimicrobial activity. Nat Rev Immunol 16(5):321–334
41. Holmdahl R, Sareila O, Olsson LM, Bäckdahl L, Wing K (2016) Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation. Immunol Rev 269(1):228–247
42. Hueber W, Sands BE, Lewitzky S et al (2012) Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn’s disease: unexpected results of a randomised, double-blind placebo-controlled trial. Gut 61(12):1693–1700
43. Hultqvist M, Olofsson P, Holmberg J, Bäckström BT, Tordsson J, Holmdahl R (2004) Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. Proc Natl Acad Sci USA 101(34):12646–12651
44. Hultqvist M, Olofsson P, Gelderman KA, Holmberg J, Holmdahl R (2006) A new arthritis therapy with oxidative burst inducers. PLoS Med 3(9):e348
45. Hultqvist M, Olofsson P, Wallner FK, Holmdahl R (2015) Pharmacological potential of NOX2 agonists in inflammatory conditions. Antioxid Redox Signal 23(5):446–459
46. + T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis 187(10):1534–1543
47. Hunter CA, Jones SA (2015) IL-6 as a keystone cytokine in health and disease. Nat Immunol 16(5):448–457
48. Iijima N, Mattei LM, Iwasaki A (2011) Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue. Proc Natl Acad Sci 108(1):284–289
49. Itariu BK, Zeyda M, Leitner L, Marculescu R, Stulnig TM (2013) Treatment with n‐3 polyunsaturated fatty acids overcomes the inverse association of vitamin D deficiency with inflammation in severely obese patients: a randomized controlled trial. PLoS one 8:e54634
50. Ito Y, Kaneko N, Iwasaki T, Morikawa S, Kaneko K, Masumoto J (2015) IL-1 as a target in inflammation. Endocr Meta Immune Disord-Drug Targets (Former Curr Drug Targets-Immune Endocr Metabol Disord) 15(3):206–211
51. Jensen AB, Moseley PL, Oprea TI et al (2014) Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients. Nat Commun 5:4022
52. + T cells. Nat Immunol 14(3):254–261
53. Jin Y, Deng Z, Cao C, Li L (2015) IL-17 polymorphisms and asthma risk: a meta-analysis of 11 single nucleotide polymorphisms. J Asthma 52(10):981–988
54. Julia C, Meunier N, Touvier M et al (2013) Dietary patterns and risk of elevated C-reactive protein concentrations 12 years later. Br J Nutr 110(04):747–754
55. Karimbux NY, Saraiya VM, Elangovan S et al (2012) Interleukin-1 gene polymorphisms and chronic periodontitis in adult whites: a systematic review and meta-analysis. J Periodontol 83(11):1407–1419
56. Khmaladze I, Kelkka T, Guerard S et al (2014) Mannan induces ROS-regulated, IL-17A–dependent psoriasis arthritis-like disease in mice. Proc Natl Acad Sci 111(35):E3669–E3678
57. Koenders MI, Marijnissen RJ, Devesa I et al (2011) Tumor necrosis factor–interleukin-17 interplay induces S100A8, interleukin-1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: rationale for combination treatment during arthritis. Arthritis Rheum 63(8):2329–2339
58. Laird E et al (2014) Vitamin D deficiency is associated with inflammation in older Irish adults. J Clin Endocrinol Metab 99:1807–1815
59. Langley RG, Elewski BE, Lebwohl M et al (2014) Secukinumab in plaque psoriasis—results of two phase 3 trials. N Engl J Med 371(4):326–338
60. Lauro ML, Burch JM, Grimes CL (2016) The effect of NOD2 on the microbiota in Crohn’s disease. Curr Opin Biotechnol 40:97–102
61. León B, López-Bravo M, Ardavín C (2007) Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity 26(4):519–531
62. Lo D, Feng L, Li L et al (1999) Integrating innate and adaptive immunity in the whole animal. Immunol Rev 169(1):225–239
63. Luchtman DW, Ellwardt E, Larochelle C, Zipp F (2014) IL-17 and related cytokines involved in the pathology and immunotherapy of multiple sclerosis: current and future developments. Cytokine Growth Factor Rev 25(4):403–413
64. + neutrophils. Liver Int 36(8):1116–1124
65. Mayer-Barber KD, Andrade BB, Barber DL et al (2011) Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection. Immunity 35(6):1023–1034
66. Mehta S, Tsai P, Lasham A, Campbell H, Reddel RR, Braithwaite A (2016) A study of TP53 RNA splicing illustrates pitfalls of RNAseq methodology. Cancer Res Canres 1624:2016
67. + T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression. Arthritis Rheumatol 66(5):1272–1281
68. Mensa-Vilaro A, De Inocencio J, Cham WT et al (2015) NOD2 mosaicism in Blau syndrome. Pediatr Rheumatol 13(1):1
69. Murphy K, Weaver C (2016) Janeway’s immunobiology. Garland Science, 9th edn, pp 1–924
70. Neuhaus J, Jacobs DR, Baker JV et al (2010) Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection. J Infect Dis 201(12):1788–1795
71. Niu Y-M, Yuan H, Zhou Y (2014) Interleukin-17 gene polymorphisms contribute to cancer risk. Mediators Inflamm 2014:128490
72. Nowlin SY, Hammer MJ, Melkus GDE (2012) Diet, inflammation, and glycemic control in type 2 diabetes: an integrative review of the literature. J Nutr Metab 2012:542698
73. Pan A, Sun Q, Bernstein AM et al (2012) Red meat consumption and mortality: results from 2 prospective cohort studies. Arch Intern Med 172(7):555–563
74. Papp K, Leonardi C, Menter A et al (2014) Safety and efficacy of brodalumab for psoriasis after 120 weeks of treatment. J Am Acad Dermatol 71(6):1183–1190 e3
75. Plander M, Kalman B (2016) Rare autoimmune disorders with Mendelian inheritance. Autoimmunity 49(5):285–297
76. + dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen. Immunity 38(2):322–335
77. Powell ND, Sloan EK, Bailey MT et al (2013) Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis. Proc Natl Acad Sci 110(41):16574–16579
78. + neutrophils increase in allergic asthmatic subjects. Allergy Asthma Clin Immunol 9(1):1
79. Rivollier A, He J, Kole A, Valatas V, Kelsall BL (2012) Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J Exp Med 209(1):139–155
80. Rohani MG, Parks WC (2015) Matrix remodeling by MMPs during wound repair. Matrix Biol 44:113–121
81. Romberg N, Al Moussawi K, Nelson-Williams C et al (2014) Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation. Nat Genet 46(10):1135–1139
82. Samraj AN, Pearce OM, Läubli H et al (2015) A red meat-derived glycan promotes inflammation and cancer progression. Proc Natl Acad Sci 112(2):542–547
83. Sanchez GAM, De Jesus AA, Goldbach‐Mansky R (2013) Monogenic autoinflammatory diseases: disorders of amplified danger sensing and cytokine dysregulation. Rheum Dis Clin North Am 39:701–734
84. Sareila O, Jaakkola N, Olofsson P, Kelkka T, Holmdahl R (2013) Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation. J Leukoc Biol 93(3):427–435
85. Sawcer S, Hellenthal G, Pirinen M et al (2011) Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476(7359):214
86. Schauer C, Janko C, Munoz LE et al (2014) Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines. Nat Med 20(5):511–517
87. Schneider G, Henrich A, Greiner G et al (2010) Cross talk between stimulated NF-κB and the tumor suppressor p53. Oncogene 29(19):2795–2806
88. Schultze-Florey CR, Martínez-Maza O, Magpantay L et al (2012) When grief makes you sick: bereavement induced systemic inflammation is a question of genotype. Brain Behav Immun 26(7):1066–1071
89. Segura E, Amigorena S (2013) Inflammatory dendritic cells in mice and humans. Trends Immunol 34(9):440–445
90. Segura E, Touzot M, Bohineust A et al (2013) Human inflammatory dendritic cells induce Th17 cell differentiation. Immunity 38(2):336–348
91. Slatter TL, Hung N, Campbell H et al (2011) Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform. Blood 117(19):5166–5177
92. Stahl EA, Raychaudhuri S, Remmers EF et al (2010) Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 42(6):508–514
93. Strowig T, Henao-Mejia J, Elinav E, Flavell R (2012) Inflammasomes in health and disease. Nature 481(7381):278–286
94. Tabas I, Glass CK (2013) Anti‐inflammatory therapy in chronic disease: challenges and opportunities. Science 339:166–172
95. Taccioli C et al (2012) Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature. Oncogene 31:4550–4558
96. Takeuchi O (2016) Posttranscriptional regulation of cytokine mrna controls the initiation and resolution of inflammation chronic inflammation. Springer, Heidelberg, pp 319–332
97. Taylor PR, Roy S, Leal SM Jr et al (2014) Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, ROR [gamma] t and dectin-2. Nat Immunol 15(2):143–151
98. Thaçi D, Blauvelt A, Reich K et al (2015) Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate to severe plaque psoriasis: CLEAR, a randomized controlled trial. J Am Acad Dermatol 73(3):400–409
99. Thomas A, Belaidi E, Aron-Wisnewsky J et al (2016) Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice. Sci Rep 6:24618
100. Tian R, Hou G, Li D, Yuan T-F (2014) A possible change process of inflammatory cytokines in the prolonged chronic stress and its ultimate implications for health. Sci World J 2014:780616
101. Tung J, Barreiro LB, Johnson ZP et al (2012) Social environment is associated with gene regulatory variation in the rhesus macaque immune system. Proc Natl Acad Sci 109(17):6490–6495
102. van Hamburg JP, Asmawidjaja P, Davelaar N et al (2011) Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production. Arthritis Rheum 63(1):73–83
103. Vanaja SK, Rathinam VA, Fitzgerald KA (2015) Mechanisms of inflammasome activation: recent advances and novel insights. Trends Cell Biol 25(5):308–315
104. Varki A (2010) Uniquely human evolution of sialic acid genetics and biology. Proc Natl Acad Sci 107(Supplement 2):8939–8946
105. Wiendl H, Dahlke F, Bennett D, Rosenkranz G, Wolf C, Bar-Or A (2015) IL-17 neutralisation by subcutaneous CJM112, a fully human anti-IL-17A monoclonal antibody for the treatment of relapsing-remitting multiple sclerosis: study design of a phase 2 trial. Immunity 51:2
106. Willrich MA, Murray DL, Snyder MR (2015) Tumor necrosis factor inhibitors: clinical utility in autoimmune diseases. Transl Res 165(2):270–282
107. Wilson R, Syed N, Shah P (2016) Erythrocytosis due to PHD2 mutations: a review of clinical presentation, diagnosis, and genetics. Case Rep Hematol 2016:6373796
108. Wong CP, Magnusson KR, Ho E (2013) Increased inflammatory response in aged mice is associated with age-related zinc deficiency and zinc transporter dysregulation. J Nutr Biochem 24:353–359
109. Wong CP, Rinaldi NA, Ho E (2015) Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation. Mol Nutr Food Res 59:991–999
110. Woo P, Humphries SE (2013) IL-6 polymorphisms: a useful genetic tool for inflammation research? J Clin Investig 123(4):1413–1414
111. Xu H, Sjögren P, Ärnlöv J et al (2015) A proinflammatory diet is associated with systemic inflammation and reduced kidney function in elderly adults. J Nutr 145(4):729–735
112. Zhang D, Chen G, Manwani D et al (2015a) Neutrophil ageing is regulated by the microbiome. Nature 525(7570):528–532
113. Zhang Z et al (2015b) Selenium deficiency facilitates inflammation through the regulation of TLR4 and TLR4-related signaling pathways in the mice uterus. Inflammation 38:1347–1356
114. Zhao L, Cheng G, Jin R et al (2016) Deletion of interleukin-6 attenuates pressure overload-induced left ventricular hypertrophy and dysfunction. Circ Res 118(12):1918–1929