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Volumn 12, Issue 1, 2016, Pages 199-207

Exendin-4 enhances expression of Neurod1 and Glut2 in insulin-producing cells derived from mouse embryonic stem cells

Author keywords

Diabetes; Embryonic stem cells; Exendin 4; Insulin producing cell

Indexed keywords

C PEPTIDE; EXENDIN 4; GLUCOSE TRANSPORTER 2; INSULIN; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR;

EID: 85010417519     PISSN: 17341922     EISSN: 18969151     Source Type: Journal    
DOI: 10.5114/aoms.2016.57596     Document Type: Article
Times cited : (12)

References (41)
  • 1
    • 0033979603 scopus 로고    scopus 로고
    • Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice
    • Soria B, Roche E, Berna G, Leon-Quinto T, Reig JA, Martin F. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 2000;49:157-62.
    • (2000) Diabetes , vol.49 , pp. 157-162
    • Soria, B.1    Roche, E.2    Berna, G.3    Leon-Quinto, T.4    Reig, J.A.5    Martin, F.6
  • 2
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulinsecreting structures similar to pancreatic islets
    • Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, Mc-Kay R. Differentiation of embryonic stem cells to insulinsecreting structures similar to pancreatic islets. Science 2001;292:1389-94.
    • (2001) Science , vol.292 , pp. 1389-1394
    • Lumelsky, N.1    Blondel, O.2    Laeng, P.3    Velasco, I.4    Ravin, R.5    Mc-Kay, R.6
  • 4
    • 13144281727 scopus 로고    scopus 로고
    • Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells
    • Blyszczuk P, Asbrand C, Rozzo A, et al. Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells. Int J Develop Biol 2004;48:1095-104.
    • (2004) Int J Develop Biol , vol.48 , pp. 1095-1104
    • Blyszczuk, P.1    Asbrand, C.2    Rozzo, A.3
  • 5
    • 33750846133 scopus 로고    scopus 로고
    • Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
    • D'Amour KA, Bang AG, Eliazer S, et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nature Biotechnol 2006;24:1392-401.
    • (2006) Nature Biotechnol , vol.24 , pp. 1392-1401
    • D'Amour, K.A.1    Bang, A.G.2    Eliazer, S.3
  • 6
    • 41849151748 scopus 로고    scopus 로고
    • Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
    • Kroon E, Martinson LA, Kadoya K, et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nature Biotechnol 2008;26:443-52.
    • (2008) Nature Biotechnol , vol.26 , pp. 443-452
    • Kroon, E.1    Martinson, L.A.2    Kadoya, K.3
  • 7
    • 0028149890 scopus 로고
    • Insulin-promoterfactor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, Edlund H. Insulin-promoterfactor 1 is required for pancreas development in mice. Nature 1994;371:606-9.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 8
    • 0029868156 scopus 로고    scopus 로고
    • PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
    • Offield MF, Jetton TL, Labosky PA, et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996;122:983-95.
    • (1996) Development , vol.122 , pp. 983-995
    • Offield, M.F.1    Jetton, T.L.2    Labosky, P.A.3
  • 10
    • 15944417831 scopus 로고    scopus 로고
    • PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance
    • Kaneto H, Nakatani Y, Miyatsuka T, et al. PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Diabetes 2005;54:1009-22.
    • (2005) Diabetes , vol.54 , pp. 1009-1022
    • Kaneto, H.1    Nakatani, Y.2    Miyatsuka, T.3
  • 11
    • 0141534119 scopus 로고    scopus 로고
    • Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis
    • Miyatsuka T, Kaneto H, Kajimoto Y, et al. Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis. Biochem Biophys Res Com 2003;310:1017-25.
    • (2003) Biochem Biophys Res Com , vol.310 , pp. 1017-1025
    • Miyatsuka, T.1    Kaneto, H.2    Kajimoto, Y.3
  • 12
    • 0033009460 scopus 로고    scopus 로고
    • The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration
    • Sharma A, Zangen DH, Reitz P, et al. The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration. Diabetes 1999;48:507-13.
    • (1999) Diabetes , vol.48 , pp. 507-513
    • Sharma, A.1    Zangen, D.H.2    Reitz, P.3
  • 13
    • 24144479748 scopus 로고    scopus 로고
    • Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas
    • Holland AM, Gonez LJ, Naselli G, Macdonald RJ, Harrison LC. Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas. Diabetes 2005;54:2586-95.
    • (2005) Diabetes , vol.54 , pp. 2586-2595
    • Holland, A.M.1    Gonez, L.J.2    Naselli, G.3    Macdonald, R.J.4    Harrison, L.C.5
  • 14
    • 0036246856 scopus 로고    scopus 로고
    • Pdx1 restores beta cell function in Irs2 knockout mice
    • Kushner JA, Ye J, Schubert M, et al. Pdx1 restores beta cell function in Irs2 knockout mice. J Clin Investig 2002;109:1193-201.
    • (2002) J Clin Investig , vol.109 , pp. 1193-1201
    • Kushner, J.A.1    Ye, J.2    Schubert, M.3
  • 15
    • 0037192799 scopus 로고    scopus 로고
    • Reduction in pancreatic transcription factor PDX-1 impairs glucosestimulated insulin secretion
    • Brissova M, Shiota M, Nicholson WE, et al. Reduction in pancreatic transcription factor PDX-1 impairs glucosestimulated insulin secretion. J Biol Chem 2002;277:11225-32.
    • (2002) J Biol Chem , vol.277 , pp. 11225-11232
    • Brissova, M.1    Shiota, M.2    Nicholson, W.E.3
  • 16
    • 9644268967 scopus 로고    scopus 로고
    • PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance
    • Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn CR. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. J Clin Investig 2004;114:828-36.
    • (2004) J Clin Investig , vol.114 , pp. 828-836
    • Kulkarni, R.N.1    Jhala, U.S.2    Winnay, J.N.3    Krajewski, S.4    Montminy, M.5    Kahn, C.R.6
  • 17
    • 68849091103 scopus 로고    scopus 로고
    • The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice
    • Oliver-Krasinski JM, Kasner MT, Yang J, et al. The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. J Clin Investig 2009;119:1888-98.
    • (2009) J Clin Investig , vol.119 , pp. 1888-1898
    • Oliver-Krasinski, J.M.1    Kasner, M.T.2    Yang, J.3
  • 19
    • 0036340074 scopus 로고    scopus 로고
    • Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
    • Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002;129:2447-57.
    • (2002) Development , vol.129 , pp. 2447-2457
    • Gu, G.1    Dubauskaite, J.2    Melton, D.A.3
  • 20
    • 0030886674 scopus 로고    scopus 로고
    • Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice
    • Naya FJ, Huang HP, Qiu Y, et al. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Develop 1997;11:2323-34.
    • (1997) Genes Develop , vol.11 , pp. 2323-2334
    • Naya, F.J.1    Huang, H.P.2    Qiu, Y.3
  • 21
    • 84860470960 scopus 로고    scopus 로고
    • Pancreatic transcription factors containing protein transduction domains drive mouse embryonic stem cells towards endocrine pancreas
    • Lima MJ, Docherty HM, Chen Y, Vallier L, Docherty K. Pancreatic transcription factors containing protein transduction domains drive mouse embryonic stem cells towards endocrine pancreas. PloS One 2012;7:e36481.
    • (2012) PloS One , vol.7 , pp. e36481
    • Lima, M.J.1    Docherty, H.M.2    Chen, Y.3    Vallier, L.4    Docherty, K.5
  • 22
    • 84888091849 scopus 로고    scopus 로고
    • The role of nateglinide and repaglinide, derivatives of meglitinide, in the treatment of type 2 diabetes mellitus
    • Guardado-Mendoza R, Prioletta A, Jimenez-Ceja LM, Sosale A, Folli F. The role of nateglinide and repaglinide, derivatives of meglitinide, in the treatment of type 2 diabetes mellitus. Arch Med Sci 2013;9:936-43.
    • (2013) Arch Med Sci , vol.9 , pp. 936-943
    • Guardado-Mendoza, R.1    Prioletta, A.2    Jimenez-Ceja, L.M.3    Sosale, A.4    Folli, F.5
  • 23
    • 84869750716 scopus 로고    scopus 로고
    • Metformin and its clinical use: New insights for an old drug in clinical practice
    • Cicero AF, Tartagni E, Ertek S. Metformin and its clinical use: new insights for an old drug in clinical practice. Arch Med Sci 2012;8:907-17.
    • (2012) Arch Med Sci , vol.8 , pp. 907-917
    • Cicero, A.F.1    Tartagni, E.2    Ertek, S.3
  • 24
    • 15444367142 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus
    • Kolterman OG, Kim DD, Shen L, et al. Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus. Am J Health Sys Pharm 2005;62:173-81.
    • (2005) Am J Health Sys Pharm , vol.62 , pp. 173-181
    • Kolterman, O.G.1    Kim, D.D.2    Shen, L.3
  • 25
    • 84932132647 scopus 로고    scopus 로고
    • Central obesity, type 2 diabetes and insulin: Exploring a pathway full of thorns
    • Papaetis GS, Papakyriakou P, Panagiotou TN. Central obesity, type 2 diabetes and insulin: exploring a pathway full of thorns. Arch Med Sci 2015;11:463-82.
    • (2015) Arch Med Sci , vol.11 , pp. 463-482
    • Papaetis, G.S.1    Papakyriakou, P.2    Panagiotou, T.N.3
  • 26
    • 37549070713 scopus 로고    scopus 로고
    • Protection of pancreatic beta-cells: Is it feasible?
    • Bonora E. Protection of pancreatic beta-cells: is it feasible? Nutr Metab Cardiovasc Dis 2008;18:74-83.
    • (2008) Nutr Metab Cardiovasc Dis , vol.18 , pp. 74-83
    • Bonora, E.1
  • 27
    • 84863978166 scopus 로고    scopus 로고
    • Latent autoimmune diabetes in adults in a population-based cohort of Polish patients with newly diagnosed diabetes mellitus
    • Szepietowska B, Glebocka A, Puch U, Gorska M, Szelachowska M. Latent autoimmune diabetes in adults in a population-based cohort of Polish patients with newly diagnosed diabetes mellitus. Arch Med Sci 2012;8:491-5.
    • (2012) Arch Med Sci , vol.8 , pp. 491-495
    • Szepietowska, B.1    Glebocka, A.2    Puch, U.3    Gorska, M.4    Szelachowska, M.5
  • 28
    • 40949136580 scopus 로고    scopus 로고
    • Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: A novel protein transduction domainbased therapy
    • Koya V, Lu S, Sun YP, et al. Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction domainbased therapy. Diabetes 2008;57:757-69.
    • (2008) Diabetes , vol.57 , pp. 757-769
    • Koya, V.1    Lu, S.2    Sun, Y.P.3
  • 29
    • 62549083921 scopus 로고    scopus 로고
    • Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells
    • Bernardo AS, Cho CH, Mason S, et al. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells. Stem Cells 2009;27:341-51.
    • (2009) Stem Cells , vol.27 , pp. 341-351
    • Bernardo, A.S.1    Cho, C.H.2    Mason, S.3
  • 30
    • 1842527497 scopus 로고    scopus 로고
    • Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells
    • Miyazaki S, Yamato E, Miyazaki J. Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells. Diabetes 2004;53:1030-7.
    • (2004) Diabetes , vol.53 , pp. 1030-1037
    • Miyazaki, S.1    Yamato, E.2    Miyazaki, J.3
  • 31
    • 80052736706 scopus 로고    scopus 로고
    • Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population
    • Kubo A, Stull R, Takeuchi M, et al. Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population. PloS One 2011;6:e24058.
    • (2011) PloS One , vol.6 , pp. e24058
    • Kubo, A.1    Stull, R.2    Takeuchi, M.3
  • 32
    • 19944432634 scopus 로고    scopus 로고
    • Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice
    • Kodama S, Toyonaga T, Kondo T, et al. Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice. Biochem Biophys Res Com 2005;327:1170-8.
    • (2005) Biochem Biophys Res Com , vol.327 , pp. 1170-1178
    • Kodama, S.1    Toyonaga, T.2    Kondo, T.3
  • 33
    • 0036134978 scopus 로고    scopus 로고
    • Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47
    • Qiu Y, Guo M, Huang S, Stein R. Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47. Mol Cell Biol 2002;22:412-20.
    • (2002) Mol Cell Biol , vol.22 , pp. 412-420
    • Qiu, Y.1    Guo, M.2    Huang, S.3    Stein, R.4
  • 34
    • 77950225021 scopus 로고    scopus 로고
    • Pancreatic beta cells require NeuroD to achieve and maintain functional maturity
    • Gu C, Stein GH, Pan N, et al. Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metabol 2010;11:298-310.
    • (2010) Cell Metabol , vol.11 , pp. 298-310
    • Gu, C.1    Stein, G.H.2    Pan, N.3
  • 35
    • 68849109257 scopus 로고    scopus 로고
    • Mouse ES cells over-expressing the transcription factor NeuroD1 show increased differentiation towards endocrine lineages and insulin-expressing cells
    • Marchand M, Schroeder IS, Markossian S, et al. Mouse ES cells over-expressing the transcription factor NeuroD1 show increased differentiation towards endocrine lineages and insulin-expressing cells. Int J Develop Biol 2009;53:569-78.
    • (2009) Int J Develop Biol , vol.53 , pp. 569-578
    • Marchand, M.1    Schroeder, I.S.2    Markossian, S.3
  • 36
    • 84874778569 scopus 로고    scopus 로고
    • Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas
    • Mastracci TL, Anderson KR, Papizan JB, Sussel L. Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas. PLoS Genet 2013;9:e1003278.
    • (2013) PLoS Genet , vol.9 , pp. e1003278
    • Mastracci, T.L.1    Anderson, K.R.2    Papizan, J.B.3    Sussel, L.4
  • 37
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: Glucagonlike peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker DJ, Nauck MA. The incretin system: glucagonlike peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006;368:1696-705.
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 38
    • 0037357951 scopus 로고    scopus 로고
    • GLP-1 receptor agonists are growth and differentiation factors for pancreatic islet beta cells
    • Egan JM, Bulotta A, Hui H, Perfetti R. GLP-1 receptor agonists are growth and differentiation factors for pancreatic islet beta cells. Diabetes Metabol Res Rev 2003;19:115-23.
    • (2003) Diabetes Metabol Res Rev , vol.19 , pp. 115-123
    • Egan, J.M.1    Bulotta, A.2    Hui, H.3    Perfetti, R.4
  • 39
    • 66149151676 scopus 로고    scopus 로고
    • GLUT2 mutations, translocation, and receptor function in diet sugar managing
    • Leturque A, Brot-Laroche E, Le Gall M. GLUT2 mutations, translocation, and receptor function in diet sugar managing. Am J Physiol Endocrinol Metabol 2009;296:E985-92.
    • (2009) Am J Physiol Endocrinol Metabol , vol.296 , pp. E985-E992
    • Leturque, A.1    Brot-Laroche, E.2    Le Gall, M.3
  • 40
    • 84878783546 scopus 로고    scopus 로고
    • Activin A, exendin-4, and glucose stimulate differentiation of human pancreatic ductal cells
    • Kim HS, Hong SH, Oh SH, Kim JH, Lee MS, Lee MK. Activin A, exendin-4, and glucose stimulate differentiation of human pancreatic ductal cells. J Endocrinol 2013;217:241-52.
    • (2013) J Endocrinol , vol.217 , pp. 241-252
    • Kim, H.S.1    Hong, S.H.2    Oh, S.H.3    Kim, J.H.4    Lee, M.S.5    Lee, M.K.6
  • 41
    • 79952986089 scopus 로고    scopus 로고
    • Exendin-4 regulates GLUT2 expression via the CaMKK/CaMKIV pathway in a pancreatic beta-cell line
    • Chen K, Yu X, Murao K, et al. Exendin-4 regulates GLUT2 expression via the CaMKK/CaMKIV pathway in a pancreatic beta-cell line. Metabol Clin Exp 2011;60:579-85.
    • (2011) Metabol Clin Exp , vol.60 , pp. 579-585
    • Chen, K.1    Yu, X.2    Murao, K.3


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