-
1
-
-
2442666735
-
Transcriptional networks controlling pancreatic development and beta cell function
-
Servitja JM, Ferrer J. Transcriptional networks controlling pancreatic development and beta cell function. Diabetologia 2004;47:597-613.
-
(2004)
Diabetologia
, vol.47
, pp. 597-613
-
-
Servitja, J.M.1
Ferrer, J.2
-
3
-
-
0025942116
-
Clonal analysis of epiblast fate during germ layer formation in the mouse embryo
-
Lawson KA, Meneses JJ, Pedersen RA. Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. Development 1991;113:891-911.
-
(1991)
Development
, vol.113
, pp. 891-911
-
-
Lawson, K.A.1
Meneses, J.J.2
Pedersen, R.A.3
-
4
-
-
0015446766
-
An ultrastructural analysis of the developing embryonic pancreas
-
Pictet RL, Clark WR, Williams RH et al. An ultrastructural analysis of the developing embryonic pancreas. Dev Biol 1972;29:436-467.
-
(1972)
Dev Biol
, vol.29
, pp. 436-467
-
-
Pictet, R.L.1
Clark, W.R.2
Williams, R.H.3
-
5
-
-
0035863135
-
Intercellular signals regulating pancreas development and function 1
-
ft-127
-
Kim SK, Hebrok M. Intercellular signals regulating pancreas development and function 1. Genes Dev 2001:15:1 ft-127.
-
(2001)
Genes Dev
, vol.15
, pp. 1
-
-
Kim, S.K.1
Hebrok, M.2
-
6
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson J. Carlsson L, Edlund T et al. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994;371:606-609.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
-
7
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
Offield MF, Jetton TL, Labosky PA et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996,122:983-995.
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
-
8
-
-
0031031571
-
Pancreatic agenesis attrib utable to a single nucleotide deletion in the human IPF1 gene coding sequence
-
Stoffers DA, Zinkin NT, Stanojevic V et al. Pancreatic agenesis attrib utable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Gen 1997;15:106-110.
-
(1997)
Nat Gen
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
-
9
-
-
0034652287
-
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
Gradwohl G, Dierich A, LeMeur M et al. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 2000;97:1607-1611.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
-
10
-
-
0033825383
-
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
-
Schwitzgebel VM, Scheel DW, Conners JR et al. Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 2000;127:3533-3542.
-
(2000)
Development
, vol.127
, pp. 3533-3542
-
-
Schwitzgebel, V.M.1
Scheel, D.W.2
Conners, J.R.3
-
11
-
-
0034775035
-
Pancreatic duodenal homeobox-L PDX-1, a major regulator of beta cell identity and function
-
McKinnon CM, Docherty K. Pancreatic duodenal homeobox-L PDX-1, a major regulator of beta cell identity and function. Diabetologia 2001;44:1203-1214.
-
(2001)
Diabetologia
, vol.44
, pp. 1203-1214
-
-
McKinnon, C.M.1
Docherty, K.2
-
12
-
-
0033602043
-
Embryonic stem cell development in a chemically defined medium
-
Wiles MV, Johansson BM. Embryonic stem cell development in a chemically defined medium. Exp Cell Res 1999;247:241-248.
-
(1999)
Exp Cell Res
, vol.247
, pp. 241-248
-
-
Wiles, M.V.1
Johansson, B.M.2
-
13
-
-
34447527158
-
Derivation of pluripotent epiblast stem cells from mammalian embryos
-
Brons IG, Smithers LE, Trotter MW et al. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 2007:448:191-195.
-
(2007)
Nature
, vol.448
, pp. 191-195
-
-
Brons, I.G.1
Smithers, L.E.2
Trotter, M.W.3
-
14
-
-
14244262504
-
Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway
-
Vallier L, Reynolds D, Pedersen RA. Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. Dev Biol 2004;275:403- 421.
-
(2004)
Dev Biol
, vol.275
, pp. 403-421
-
-
Vallier, L.1
Reynolds, D.2
Pedersen, R.A.3
-
15
-
-
0348141717
-
Enhancing and diminishing gene function in human embryonic stem cells
-
Vallier L, Rugg-Gunn PJ, Bouhon IA et al. Enhancing and diminishing gene function in human embryonic stem cells. STEM CELLS 2004;22:2-11.
-
(2004)
STEM CELLS
, vol.22
, pp. 2-11
-
-
Vallier, L.1
Rugg-Gunn, P.J.2
Bouhon, I.A.3
-
16
-
-
23644438592
-
Relative contribution of PDX-1, Mafa and E47/bela2 to the regulation of the human insulin promoter
-
Docherty HM, Hay CW, Ferguson LA et al. Relative contribution of PDX-1, Mafa and E47/bela2 to the regulation of the human insulin promoter. Biochem J 2005;389:813-820.
-
(2005)
Biochem J
, vol.389
, pp. 813-820
-
-
Docherty, H.M.1
Hay, C.W.2
Ferguson, L.A.3
-
17
-
-
0033571243
-
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases
-
Indra AK, Warot X, Broeard J et al. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res 1999;27:4324-4327.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4324-4327
-
-
Indra, A.K.1
Warot, X.2
Broeard, J.3
-
18
-
-
34547119051
-
Conditional gene expression in human embryonic stem cells
-
Vallier L, Alexander M, Pedersen R. Conditional gene expression in human embryonic stem cells. STEM CELLS 2007;25:1490-1497.
-
(2007)
STEM CELLS
, vol.25
, pp. 1490-1497
-
-
Vallier, L.1
Alexander, M.2
Pedersen, R.3
-
19
-
-
23844496075
-
Glucagon-like peptide-1 stimulates human insulin promoter activity in part through cAMP-responsive elements that lie upstream and downstream of the transcription start site
-
Hay CW, Sinclair EM, Bermano G et al. Glucagon-like peptide-1 stimulates human insulin promoter activity in part through cAMP-responsive elements that lie upstream and downstream of the transcription start site. J Endocrinol 2005; 186:353-365.
-
(2005)
J Endocrinol
, vol.186
, pp. 353-365
-
-
Hay, C.W.1
Sinclair, E.M.2
Bermano, G.3
-
20
-
-
2342424743
-
Development of definitive endoderm from embryonic stem cells in culture
-
Kubo A, Shinozaki K, Shannon JM et al. Development of definitive endoderm from embryonic stem cells in culture. Development 2004; 131:1651-1662.
-
(2004)
Development
, vol.131
, pp. 1651-1662
-
-
Kubo, A.1
Shinozaki, K.2
Shannon, J.M.3
-
21
-
-
28644442419
-
Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells
-
Yasunaga M, Tada S, Torikai-Nishikawa S et al. Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol 2005:23:1542-1550.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1542-1550
-
-
Yasunaga, M.1
Tada, S.2
Torikai-Nishikawa, S.3
-
22
-
-
3042733135
-
A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells
-
Park C, Afrikanova I, Chung YS et al. A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development 2004; 131:2749-2762.
-
(2004)
Development
, vol.131
, pp. 2749-2762
-
-
Park, C.1
Afrikanova, I.2
Chung, Y.S.3
-
23
-
-
33750936779
-
Wnt and TGF-beta signaling arc required for the induction of an in vitro model of primitive streak formation using embryonic stem cells
-
Gadue P, Hubcr TL, Paddison PJ et al. Wnt and TGF-beta signaling arc required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proc Natl Acad Sci USA 2006;103:16806-16811.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16806-16811
-
-
Gadue, P.1
Hubcr, T.L.2
Paddison, P.J.3
-
24
-
-
27644504639
-
Characterization of mesendoderm: A diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture
-
Tada S, Era T, Furusawa C et al. Characterization of mesendoderm: A diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development 2005;132:4363-4374.
-
(2005)
Development
, vol.132
, pp. 4363-4374
-
-
Tada, S.1
Era, T.2
Furusawa, C.3
-
25
-
-
25844433114
-
Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels
-
Bengtsson M, Slahlberg A, Rorsman P et al. Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels. Genome Res 2005;15:1388-1392.
-
(2005)
Genome Res
, vol.15
, pp. 1388-1392
-
-
Bengtsson, M.1
Slahlberg, A.2
Rorsman, P.3
-
26
-
-
25844522522
-
The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas
-
Hale MA, Kagami H, Shi L et al. The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas. Dev Biol 2005;286:225-237.
-
(2005)
Dev Biol
, vol.286
, pp. 225-237
-
-
Hale, M.A.1
Kagami, H.2
Shi, L.3
-
27
-
-
40949099880
-
Pdx-1 and Ptfla concurrently determine fate specification of pancreatic multipotent progenitor cells
-
Burlison JS, Long Q, Fujitani Y el al. Pdx-1 and Ptfla concurrently determine fate specification of pancreatic multipotent progenitor cells. Dev Biol 2008;316:74-86.
-
(2008)
Dev Biol
, vol.316
, pp. 74-86
-
-
Burlison, J.S.1
Long, Q.2
Fujitani, Y.3
el al4
-
28
-
-
33645281942
-
IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas
-
Mellitzer G, Bonne S, Luco RF et al. IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas. EMBO J 2006;25:1344-1352.
-
(2006)
EMBO J
, vol.25
, pp. 1344-1352
-
-
Mellitzer, G.1
Bonne, S.2
Luco, R.F.3
-
29
-
-
0034524101
-
Homeobox gene nkx6.1 lies downstream of nkx2.2 in the major pathway of alpha and beta-cell formation in the pancreas
-
Sander M, Sussel L, Conners J et al. Homeobox gene nkx6.1 lies downstream of nkx2.2 in the major pathway of alpha and beta-cell formation in the pancreas. Development 2000;127:5533-5540.
-
(2000)
Development
, vol.127
, pp. 5533-5540
-
-
Sander, M.1
Sussel, L.2
Conners, J.3
-
30
-
-
23144432613
-
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha-and beta-cell lineages in the mouse endocrine pancreas
-
Collombat P, Hecksher-Sorensen J, Broccoli V et al. The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha-and beta-cell lineages in the mouse endocrine pancreas. Development 2005;132:2969-2980.
-
(2005)
Development
, vol.132
, pp. 2969-2980
-
-
Collombat, P.1
Hecksher-Sorensen, J.2
Broccoli, V.3
-
31
-
-
33646194560
-
A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells
-
Nishimura W, Kondo T, Salameb T et al. A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol 2006;293:526-539.
-
(2006)
Dev Biol
, vol.293
, pp. 526-539
-
-
Nishimura, W.1
Kondo, T.2
Salameb, T.3
-
32
-
-
38949149704
-
Pdx-1 Function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
-
Gannon M, Abies ET, Crawford L et al. Pdx-1 Function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis. Dev Biol 2008;314:406-417.
-
(2008)
Dev Biol
, vol.314
, pp. 406-417
-
-
Gannon, M.1
Abies, E.T.2
Crawford, L.3
-
33
-
-
0027308108
-
Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide
-
Teitelman G, Alpert S. Polak JM et al. Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide. Development 1993;118:1031-1039.
-
(1993)
Development
, vol.118
, pp. 1031-1039
-
-
Teitelman, G.1
Alpert, S.2
Polak, J.M.3
-
34
-
-
0026321596
-
Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene
-
Herrera PL, Huarte J, Sanvito F et al. Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development 1991;113:1257-1265.
-
(1991)
Development
, vol.113
, pp. 1257-1265
-
-
Herrera, P.L.1
Huarte, J.2
Sanvito, F.3
-
35
-
-
0037417958
-
-
Bly3szczuk P, Czyz J, Kania G et al. Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc Natl Acad Sci USA 2003;100:998-1003.
-
Bly3szczuk P, Czyz J, Kania G et al. Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc Natl Acad Sci USA 2003;100:998-1003.
-
-
-
-
36
-
-
33749185455
-
The effect of overexpression of Pdx 1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells
-
Lavon N, Yanuka O, Benvenisty N. The effect of overexpression of Pdx 1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells. STEM CELLS 2006;24:1923-1930.
-
(2006)
STEM CELLS
, vol.24
, pp. 1923-1930
-
-
Lavon, N.1
Yanuka, O.2
Benvenisty, N.3
-
37
-
-
1842527497
-
Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells
-
Miyazaki S, Yamato E, Miyazaki J. Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells. Diabetes 2004;53:1030-1037.
-
(2004)
Diabetes
, vol.53
, pp. 1030-1037
-
-
Miyazaki, S.1
Yamato, E.2
Miyazaki, J.3
-
38
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou Q, Brown J, Kanarek A et al. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008;455:627-632.
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
-
39
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
D'Amour KA, Bang AG, Eliazer S el al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006;24:1392-1401.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
el al4
-
41
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
|