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Volumn 27, Issue 2, 2009, Pages 341-351

Biphasic Induction of Pdx1 in moose and human embryonic stem cells can mimic development of pancreatic β-cells

Author keywords

Diabetes mellitus; Insulin gene; Pancreatic differentiation; Stem cells

Indexed keywords

CELL MARKER; INSULIN; TRANSCRIPTION FACTOR PDX 1;

EID: 62549083921     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2008-0310     Document Type: Article
Times cited : (54)

References (41)
  • 1
    • 2442666735 scopus 로고    scopus 로고
    • Transcriptional networks controlling pancreatic development and beta cell function
    • Servitja JM, Ferrer J. Transcriptional networks controlling pancreatic development and beta cell function. Diabetologia 2004;47:597-613.
    • (2004) Diabetologia , vol.47 , pp. 597-613
    • Servitja, J.M.1    Ferrer, J.2
  • 2
    • 33746817104 scopus 로고    scopus 로고
    • Specifying pancreatic endocrine cell fates
    • Collombat P, Hecksher-Sorensen J, Serup P et al. Specifying pancreatic endocrine cell fates. Mech Dev 2006;123:501-512.
    • (2006) Mech Dev , vol.123 , pp. 501-512
    • Collombat, P.1    Hecksher-Sorensen, J.2    Serup, P.3
  • 3
    • 0025942116 scopus 로고
    • Clonal analysis of epiblast fate during germ layer formation in the mouse embryo
    • Lawson KA, Meneses JJ, Pedersen RA. Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. Development 1991;113:891-911.
    • (1991) Development , vol.113 , pp. 891-911
    • Lawson, K.A.1    Meneses, J.J.2    Pedersen, R.A.3
  • 4
    • 0015446766 scopus 로고
    • An ultrastructural analysis of the developing embryonic pancreas
    • Pictet RL, Clark WR, Williams RH et al. An ultrastructural analysis of the developing embryonic pancreas. Dev Biol 1972;29:436-467.
    • (1972) Dev Biol , vol.29 , pp. 436-467
    • Pictet, R.L.1    Clark, W.R.2    Williams, R.H.3
  • 5
    • 0035863135 scopus 로고    scopus 로고
    • Intercellular signals regulating pancreas development and function 1
    • ft-127
    • Kim SK, Hebrok M. Intercellular signals regulating pancreas development and function 1. Genes Dev 2001:15:1 ft-127.
    • (2001) Genes Dev , vol.15 , pp. 1
    • Kim, S.K.1    Hebrok, M.2
  • 6
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J. Carlsson L, Edlund T et al. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994;371:606-609.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3
  • 7
    • 0029868156 scopus 로고    scopus 로고
    • PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
    • Offield MF, Jetton TL, Labosky PA et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996,122:983-995.
    • (1996) Development , vol.122 , pp. 983-995
    • Offield, M.F.1    Jetton, T.L.2    Labosky, P.A.3
  • 8
    • 0031031571 scopus 로고    scopus 로고
    • Pancreatic agenesis attrib utable to a single nucleotide deletion in the human IPF1 gene coding sequence
    • Stoffers DA, Zinkin NT, Stanojevic V et al. Pancreatic agenesis attrib utable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Gen 1997;15:106-110.
    • (1997) Nat Gen , vol.15 , pp. 106-110
    • Stoffers, D.A.1    Zinkin, N.T.2    Stanojevic, V.3
  • 9
    • 0034652287 scopus 로고    scopus 로고
    • neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
    • Gradwohl G, Dierich A, LeMeur M et al. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 2000;97:1607-1611.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1607-1611
    • Gradwohl, G.1    Dierich, A.2    LeMeur, M.3
  • 10
    • 0033825383 scopus 로고    scopus 로고
    • Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
    • Schwitzgebel VM, Scheel DW, Conners JR et al. Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 2000;127:3533-3542.
    • (2000) Development , vol.127 , pp. 3533-3542
    • Schwitzgebel, V.M.1    Scheel, D.W.2    Conners, J.R.3
  • 11
    • 0034775035 scopus 로고    scopus 로고
    • Pancreatic duodenal homeobox-L PDX-1, a major regulator of beta cell identity and function
    • McKinnon CM, Docherty K. Pancreatic duodenal homeobox-L PDX-1, a major regulator of beta cell identity and function. Diabetologia 2001;44:1203-1214.
    • (2001) Diabetologia , vol.44 , pp. 1203-1214
    • McKinnon, C.M.1    Docherty, K.2
  • 12
    • 0033602043 scopus 로고    scopus 로고
    • Embryonic stem cell development in a chemically defined medium
    • Wiles MV, Johansson BM. Embryonic stem cell development in a chemically defined medium. Exp Cell Res 1999;247:241-248.
    • (1999) Exp Cell Res , vol.247 , pp. 241-248
    • Wiles, M.V.1    Johansson, B.M.2
  • 13
    • 34447527158 scopus 로고    scopus 로고
    • Derivation of pluripotent epiblast stem cells from mammalian embryos
    • Brons IG, Smithers LE, Trotter MW et al. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 2007:448:191-195.
    • (2007) Nature , vol.448 , pp. 191-195
    • Brons, I.G.1    Smithers, L.E.2    Trotter, M.W.3
  • 14
    • 14244262504 scopus 로고    scopus 로고
    • Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway
    • Vallier L, Reynolds D, Pedersen RA. Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. Dev Biol 2004;275:403- 421.
    • (2004) Dev Biol , vol.275 , pp. 403-421
    • Vallier, L.1    Reynolds, D.2    Pedersen, R.A.3
  • 15
    • 0348141717 scopus 로고    scopus 로고
    • Enhancing and diminishing gene function in human embryonic stem cells
    • Vallier L, Rugg-Gunn PJ, Bouhon IA et al. Enhancing and diminishing gene function in human embryonic stem cells. STEM CELLS 2004;22:2-11.
    • (2004) STEM CELLS , vol.22 , pp. 2-11
    • Vallier, L.1    Rugg-Gunn, P.J.2    Bouhon, I.A.3
  • 16
    • 23644438592 scopus 로고    scopus 로고
    • Relative contribution of PDX-1, Mafa and E47/bela2 to the regulation of the human insulin promoter
    • Docherty HM, Hay CW, Ferguson LA et al. Relative contribution of PDX-1, Mafa and E47/bela2 to the regulation of the human insulin promoter. Biochem J 2005;389:813-820.
    • (2005) Biochem J , vol.389 , pp. 813-820
    • Docherty, H.M.1    Hay, C.W.2    Ferguson, L.A.3
  • 17
    • 0033571243 scopus 로고    scopus 로고
    • Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases
    • Indra AK, Warot X, Broeard J et al. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res 1999;27:4324-4327.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4324-4327
    • Indra, A.K.1    Warot, X.2    Broeard, J.3
  • 18
    • 34547119051 scopus 로고    scopus 로고
    • Conditional gene expression in human embryonic stem cells
    • Vallier L, Alexander M, Pedersen R. Conditional gene expression in human embryonic stem cells. STEM CELLS 2007;25:1490-1497.
    • (2007) STEM CELLS , vol.25 , pp. 1490-1497
    • Vallier, L.1    Alexander, M.2    Pedersen, R.3
  • 19
    • 23844496075 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 stimulates human insulin promoter activity in part through cAMP-responsive elements that lie upstream and downstream of the transcription start site
    • Hay CW, Sinclair EM, Bermano G et al. Glucagon-like peptide-1 stimulates human insulin promoter activity in part through cAMP-responsive elements that lie upstream and downstream of the transcription start site. J Endocrinol 2005; 186:353-365.
    • (2005) J Endocrinol , vol.186 , pp. 353-365
    • Hay, C.W.1    Sinclair, E.M.2    Bermano, G.3
  • 20
    • 2342424743 scopus 로고    scopus 로고
    • Development of definitive endoderm from embryonic stem cells in culture
    • Kubo A, Shinozaki K, Shannon JM et al. Development of definitive endoderm from embryonic stem cells in culture. Development 2004; 131:1651-1662.
    • (2004) Development , vol.131 , pp. 1651-1662
    • Kubo, A.1    Shinozaki, K.2    Shannon, J.M.3
  • 21
    • 28644442419 scopus 로고    scopus 로고
    • Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells
    • Yasunaga M, Tada S, Torikai-Nishikawa S et al. Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol 2005:23:1542-1550.
    • (2005) Nat Biotechnol , vol.23 , pp. 1542-1550
    • Yasunaga, M.1    Tada, S.2    Torikai-Nishikawa, S.3
  • 22
    • 3042733135 scopus 로고    scopus 로고
    • A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells
    • Park C, Afrikanova I, Chung YS et al. A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development 2004; 131:2749-2762.
    • (2004) Development , vol.131 , pp. 2749-2762
    • Park, C.1    Afrikanova, I.2    Chung, Y.S.3
  • 23
    • 33750936779 scopus 로고    scopus 로고
    • Wnt and TGF-beta signaling arc required for the induction of an in vitro model of primitive streak formation using embryonic stem cells
    • Gadue P, Hubcr TL, Paddison PJ et al. Wnt and TGF-beta signaling arc required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proc Natl Acad Sci USA 2006;103:16806-16811.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 16806-16811
    • Gadue, P.1    Hubcr, T.L.2    Paddison, P.J.3
  • 24
    • 27644504639 scopus 로고    scopus 로고
    • Characterization of mesendoderm: A diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture
    • Tada S, Era T, Furusawa C et al. Characterization of mesendoderm: A diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development 2005;132:4363-4374.
    • (2005) Development , vol.132 , pp. 4363-4374
    • Tada, S.1    Era, T.2    Furusawa, C.3
  • 25
    • 25844433114 scopus 로고    scopus 로고
    • Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels
    • Bengtsson M, Slahlberg A, Rorsman P et al. Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels. Genome Res 2005;15:1388-1392.
    • (2005) Genome Res , vol.15 , pp. 1388-1392
    • Bengtsson, M.1    Slahlberg, A.2    Rorsman, P.3
  • 26
    • 25844522522 scopus 로고    scopus 로고
    • The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas
    • Hale MA, Kagami H, Shi L et al. The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas. Dev Biol 2005;286:225-237.
    • (2005) Dev Biol , vol.286 , pp. 225-237
    • Hale, M.A.1    Kagami, H.2    Shi, L.3
  • 27
    • 40949099880 scopus 로고    scopus 로고
    • Pdx-1 and Ptfla concurrently determine fate specification of pancreatic multipotent progenitor cells
    • Burlison JS, Long Q, Fujitani Y el al. Pdx-1 and Ptfla concurrently determine fate specification of pancreatic multipotent progenitor cells. Dev Biol 2008;316:74-86.
    • (2008) Dev Biol , vol.316 , pp. 74-86
    • Burlison, J.S.1    Long, Q.2    Fujitani, Y.3    el al4
  • 28
    • 33645281942 scopus 로고    scopus 로고
    • IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas
    • Mellitzer G, Bonne S, Luco RF et al. IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas. EMBO J 2006;25:1344-1352.
    • (2006) EMBO J , vol.25 , pp. 1344-1352
    • Mellitzer, G.1    Bonne, S.2    Luco, R.F.3
  • 29
    • 0034524101 scopus 로고    scopus 로고
    • Homeobox gene nkx6.1 lies downstream of nkx2.2 in the major pathway of alpha and beta-cell formation in the pancreas
    • Sander M, Sussel L, Conners J et al. Homeobox gene nkx6.1 lies downstream of nkx2.2 in the major pathway of alpha and beta-cell formation in the pancreas. Development 2000;127:5533-5540.
    • (2000) Development , vol.127 , pp. 5533-5540
    • Sander, M.1    Sussel, L.2    Conners, J.3
  • 30
    • 23144432613 scopus 로고    scopus 로고
    • The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha-and beta-cell lineages in the mouse endocrine pancreas
    • Collombat P, Hecksher-Sorensen J, Broccoli V et al. The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha-and beta-cell lineages in the mouse endocrine pancreas. Development 2005;132:2969-2980.
    • (2005) Development , vol.132 , pp. 2969-2980
    • Collombat, P.1    Hecksher-Sorensen, J.2    Broccoli, V.3
  • 31
    • 33646194560 scopus 로고    scopus 로고
    • A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells
    • Nishimura W, Kondo T, Salameb T et al. A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol 2006;293:526-539.
    • (2006) Dev Biol , vol.293 , pp. 526-539
    • Nishimura, W.1    Kondo, T.2    Salameb, T.3
  • 32
    • 38949149704 scopus 로고    scopus 로고
    • Pdx-1 Function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
    • Gannon M, Abies ET, Crawford L et al. Pdx-1 Function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis. Dev Biol 2008;314:406-417.
    • (2008) Dev Biol , vol.314 , pp. 406-417
    • Gannon, M.1    Abies, E.T.2    Crawford, L.3
  • 33
    • 0027308108 scopus 로고
    • Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide
    • Teitelman G, Alpert S. Polak JM et al. Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide. Development 1993;118:1031-1039.
    • (1993) Development , vol.118 , pp. 1031-1039
    • Teitelman, G.1    Alpert, S.2    Polak, J.M.3
  • 34
    • 0026321596 scopus 로고
    • Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene
    • Herrera PL, Huarte J, Sanvito F et al. Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development 1991;113:1257-1265.
    • (1991) Development , vol.113 , pp. 1257-1265
    • Herrera, P.L.1    Huarte, J.2    Sanvito, F.3
  • 35
    • 0037417958 scopus 로고    scopus 로고
    • Bly3szczuk P, Czyz J, Kania G et al. Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc Natl Acad Sci USA 2003;100:998-1003.
    • Bly3szczuk P, Czyz J, Kania G et al. Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc Natl Acad Sci USA 2003;100:998-1003.
  • 36
    • 33749185455 scopus 로고    scopus 로고
    • The effect of overexpression of Pdx 1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells
    • Lavon N, Yanuka O, Benvenisty N. The effect of overexpression of Pdx 1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells. STEM CELLS 2006;24:1923-1930.
    • (2006) STEM CELLS , vol.24 , pp. 1923-1930
    • Lavon, N.1    Yanuka, O.2    Benvenisty, N.3
  • 37
    • 1842527497 scopus 로고    scopus 로고
    • Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells
    • Miyazaki S, Yamato E, Miyazaki J. Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells. Diabetes 2004;53:1030-1037.
    • (2004) Diabetes , vol.53 , pp. 1030-1037
    • Miyazaki, S.1    Yamato, E.2    Miyazaki, J.3
  • 38
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
    • Zhou Q, Brown J, Kanarek A et al. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008;455:627-632.
    • (2008) Nature , vol.455 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3
  • 39
    • 33750846133 scopus 로고    scopus 로고
    • Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
    • D'Amour KA, Bang AG, Eliazer S el al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006;24:1392-1401.
    • (2006) Nat Biotechnol , vol.24 , pp. 1392-1401
    • D'Amour, K.A.1    Bang, A.G.2    Eliazer, S.3    el al4
  • 41
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2


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