Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells

Genes and Cancer

Volumn 7, Issue 7-8, 2016, Pages 260-277

  Villanueva Paz, Marina ^a   Cordero, Mario D ^b   Pavón, Ana Delgado ^a   Vega, Beatriz Castejón ^a   Cotán, David ^a   De la Mata, Mario ^a   Oropesa Ávila, Manuel ^a   Alcocer Gomez, Elizabet ^a   de Lavera, Isabel ^a   Garrido Maraver, Juan ^a   Carrascosa, José ^a   Zaderenko, Ana Paula ^a   Muntané, Jordi ^c,e   de Miguel, Manuel ^d   Sánchez Alcázar, José Antonio ^a,f  

^a UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^d UNIVERSITY OF SEVILLE   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Amitriptyline; Apoptosis; HepG2 cells; Mitophagy; Oxidative stress

Indexed keywords

ALPHA TOCOPHEROL; AMITRIPTYLINE; AUTOPHAGY RELATED PROTEIN 12; AUTOPHAGY RELATED PROTEIN 5; BAFILOMYCIN A1; BECLIN 1; BETA GALACTOSIDASE; BUTYLATED HYDROXYANISOLE; CATHEPSIN B; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; LC3 PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; PARKIN; PEPTIDES AND PROTEINS; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE; UBIDECARENONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; CELL PERMEABILIZATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DENSITOMETRY; EMBRYO; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOPHAGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

EID: 85009947502     PISSN: 19476019     EISSN: 19476027     Source Type: Journal    
DOI: None     Document Type: Article

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