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Volumn 53, Issue 5, 2004, Pages 461-470

Characteristics of the killing mechanism of human natural killer cells against hepatocellular carcinoma cell lines HepG2 and Hep3B

Author keywords

Apoptosis; Cytotoxicity; Death receptors ligands; Hepatocellular carcinoma cells; NK cells; Perforin and granzymes

Indexed keywords

TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; APOPTOSIS REGULATORY PROTEIN; CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; FAS LIGAND; FASLG PROTEIN, HUMAN; MEMBRANE PROTEIN; TNFRSF10A PROTEIN, HUMAN; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 2342566957     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-003-0461-0     Document Type: Article
Times cited : (33)

References (63)
  • 1
    • 0028962125 scopus 로고
    • Fas-mediated cytotoxicity by freshly isolated natural killer cells
    • Arase H, Arase N, Saito T (1995) Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 181:1235
    • (1995) J Exp Med , vol.181 , pp. 1235
    • Arase, H.1    Arase, N.2    Saito, T.3
  • 2
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM (1998) Death receptors: signaling and modulation. Science 281:1305
    • (1998) Science , vol.281 , pp. 1305
    • Ashkenazi, A.1    Dixit, V.M.2
  • 3
    • 0025060392 scopus 로고
    • Natural killer cell activity in patients with hepatocellular carcinoma relative to early development and tumor invasion
    • Chuang W, Liu HW, Chang WY (1990) Natural killer cell activity in patients with hepatocellular carcinoma relative to early development and tumor invasion. Cancer 65:926
    • (1990) Cancer , vol.65 , pp. 926
    • Chuang, W.1    Liu, H.W.2    Chang, W.Y.3
  • 4
    • 0011123295 scopus 로고
    • Endogenous endonuclease-induced DNA fragmentation: An early event in cell-mediated cytolysis
    • Duke RC, Chervenak R, Cohen JJ (1983) Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis. Proc Natl Acad Sci USA 80:6361
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 6361
    • Duke, R.C.1    Chervenak, R.2    Cohen, J.J.3
  • 5
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshaw WC, Martins LM, Kaufmann SH (1999) Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 68:383
    • (1999) Annu Rev Biochem , vol.68 , pp. 383
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 6
    • 0030982279 scopus 로고    scopus 로고
    • Liver Apoptosis
    • Feldmann G (1997) Liver Apoptosis. J Hepatol 26:1
    • (1997) J Hepatol , vol.26 , pp. 1
    • Feldmann, G.1
  • 7
    • 0027973061 scopus 로고
    • CPP32: A novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme
    • Fernandes-Alnemri T, Litwack G, Alnemri ES (1994) CPP32: a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J Biol Chem 269:30761
    • (1994) J Biol Chem , vol.269 , pp. 30761
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 9
    • 0031950395 scopus 로고    scopus 로고
    • CD95-induced apoptosis in human liver disease
    • Galle PR, Krammer PH (1998) CD95-induced apoptosis in human liver disease. Semin Liver Dis 18:141
    • (1998) Semin Liver Dis , vol.18 , pp. 141
    • Galle, P.R.1    Krammer, P.H.2
  • 10
    • 0021249999 scopus 로고
    • Evaluation of the role of natural killer cells in radiation-induced leukemogenesis in mice
    • Gorelik E, Rosen B, Copeland D, Weatherly B, Herberman RB (1984) Evaluation of the role of natural killer cells in radiation-induced leukemogenesis in mice. J Natl Cancer Inst 72:1397
    • (1984) J Natl Cancer Inst , vol.72 , pp. 1397
    • Gorelik, E.1    Rosen, B.2    Copeland, D.3    Weatherly, B.4    Herberman, R.B.5
  • 11
    • 0030035921 scopus 로고    scopus 로고
    • Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues
    • Higaki K, Yano H, Kojiro M (1996) Fas antigen expression and its relationship with apoptosis in human hepatocellular carcinoma and noncancerous tissues. Am J Pathol 149:429
    • (1996) Am J Pathol , vol.149 , pp. 429
    • Higaki, K.1    Yano, H.2    Kojiro, M.3
  • 12
    • 0023256944 scopus 로고
    • Natural killer and activated killer activities in chronic liver disease and hepatocellular carcinoma: Evidence for a decreased lymphokine induced activity of effector cells
    • Hirofuji H, Kakumu S, Fiji A, Ohtani Y, Murase K, Tahara H (1987) Natural killer and activated killer activities in chronic liver disease and hepatocellular carcinoma: evidence for a decreased lymphokine induced activity of effector cells. Clin Exp Immunol 68:348
    • (1987) Clin Exp Immunol , vol.68 , pp. 348
    • Hirofuji, H.1    Kakumu, S.2    Fiji, A.3    Ohtani, Y.4    Murase, K.5    Tahara, H.6
  • 13
    • 0034905394 scopus 로고    scopus 로고
    • XIAP: Apoptotic brake and promissing therapeutic target
    • Holcik M, Gibson H, Korneluk RG (2001) XIAP: apoptotic brake and promissing therapeutic target. Apoptosis 6:253
    • (2001) Apoptosis , vol.6 , pp. 253
    • Holcik, M.1    Gibson, H.2    Korneluk, R.G.3
  • 15
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M, Kim TH, Seol DW, Esplen JE, Dorko K, Billiar TR, Strom SC (2000) Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 6:564
    • (2000) Nat Med , vol.6 , pp. 564
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3    Esplen, J.E.4    Dorko, K.5    Billiar, T.R.6    Strom, S.C.7
  • 17
    • 0033571332 scopus 로고    scopus 로고
    • Constitutive expression and role of the TNF family ligands in apoptotic killing of tumor cells by human NK cells
    • Kashii Y, Giorda R, Herberman RB, Whiteside TL, Vujanovic NL (1999) Constitutive expression and role of the TNF family ligands in apoptotic killing of tumor cells by human NK cells. J Immunol 163:5358
    • (1999) J Immunol , vol.163 , pp. 5358
    • Kashii, Y.1    Giorda, R.2    Herberman, R.B.3    Whiteside, T.L.4    Vujanovic, N.L.5
  • 19
    • 0036895749 scopus 로고    scopus 로고
    • TRAIL-mediated apoptosis requires NF-kB inhibition and the mitochondrial permeability transition in human hepatoma cells
    • Kim YS, Schwabe RF, Qian T, Lemasters JJ, Brenner DA (2002) TRAIL-mediated apoptosis requires NF-kB inhibition and the mitochondrial permeability transition in human hepatoma cells. Hepatology 36:1498
    • (2002) Hepatology , vol.36 , pp. 1498
    • Kim, Y.S.1    Schwabe, R.F.2    Qian, T.3    Lemasters, J.J.4    Brenner, D.A.5
  • 20
    • 0031002790 scopus 로고    scopus 로고
    • Essential roles of the Fas ligand in the development of hepatitis
    • Kondo T, Suda T, Fukuyama H, Adachi M, Nagata S (1997) Essential roles of the Fas ligand in the development of hepatitis. Nat Med 3:409
    • (1997) Nat Med , vol.3 , pp. 409
    • Kondo, T.1    Suda, T.2    Fukuyama, H.3    Adachi, M.4    Nagata, S.5
  • 22
    • 0036192025 scopus 로고    scopus 로고
    • Overexpression of the mouse Fas gene in human Hep3B hepatoma cells overcomes their resistance to Fas-mediated apoptosis
    • Lamboley C, Bringuier AF, Camus E, Lardeux B, Groyer A, Feldmann G (2002) Overexpression of the mouse Fas gene in human Hep3B hepatoma cells overcomes their resistance to Fas-mediated apoptosis. J Hepatol 36:385
    • (2002) J Hepatol , vol.36 , pp. 385
    • Lamboley, C.1    Bringuier, A.F.2    Camus, E.3    Lardeux, B.4    Groyer, A.5    Feldmann, G.6
  • 23
    • 0030240077 scopus 로고    scopus 로고
    • Perfolin, Fas ligand, and tumor necrosis factor are the major cytototoxic molecules used by lymphokine-activated killer cells
    • Lee RK, Spielman J, Zhao DY, Olsen KJ, Podack ER (1996) Perfolin, Fas ligand, and tumor necrosis factor are the major cytototoxic molecules used by lymphokine-activated killer cells. J Immunol 157:1919
    • (1996) J Immunol , vol.157 , pp. 1919
    • Lee, R.K.1    Spielman, J.2    Zhao, D.Y.3    Olsen, K.J.4    Podack, E.R.5
  • 24
    • 0030848994 scopus 로고    scopus 로고
    • Signal transduction during natural killer cell activation: Inside the mind of a killer
    • Leibson PJ (1997) Signal transduction during natural killer cell activation: inside the mind of a killer. Immunity 6:655
    • (1997) Immunity , vol.6 , pp. 655
    • Leibson, P.J.1
  • 25
    • 0027946007 scopus 로고
    • A null mutation in the perforin gene impairs cytolytic T lymphocyte-and natural killer cell-mediated cytotoxicity
    • Lowin B, Beermann F, Schmidt A, Tschopp J (1994) A null mutation in the perforin gene impairs cytolytic T lymphocyte-and natural killer cell-mediated cytotoxicity. Proc Natl Acad Sci USA 91:11571
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11571
    • Lowin, B.1    Beermann, F.2    Schmidt, A.3    Tschopp, J.4
  • 26
    • 0025792001 scopus 로고
    • The JAM test: A simple assay for DNA fragmentation and cell death
    • Matzinger P (1991) The JAM test: a simple assay for DNA fragmentation and cell death. J Immunol Methods 145:185
    • (1991) J Immunol Methods , vol.145 , pp. 185
    • Matzinger, P.1
  • 30
    • 0023495315 scopus 로고
    • Relationship between natural killer activity and development of hepatocellular carcinoma in patients with cirrhosis of the liver
    • Nakajima T, Mizushima N, Kanai K (1987) Relationship between natural killer activity and development of hepatocellular carcinoma in patients with cirrhosis of the liver. Jpn J Clin Oncol 17:327
    • (1987) Jpn J Clin Oncol , vol.17 , pp. 327
    • Nakajima, T.1    Mizushima, N.2    Kanai, K.3
  • 34
    • 0030265706 scopus 로고    scopus 로고
    • Involvement of Fas ligand and Fas-mediated pathway in the cytotoxicity of human natural killer cells
    • Oshmi Y, Oda S, Honda Y, Nagata S, Miyazaki S (1996) Involvement of Fas ligand and Fas-mediated pathway in the cytotoxicity of human natural killer cells. J Immunol 157:2909
    • (1996) J Immunol , vol.157 , pp. 2909
    • Oshmi, Y.1    Oda, S.2    Honda, Y.3    Nagata, S.4    Miyazaki, S.5
  • 35
    • 0029778891 scopus 로고    scopus 로고
    • 2+ response patterns in target cells attacked by human natural killer cells
    • 2+ response patterns in target cells attacked by human natural killer cells. J Physiol 495:319
    • (1996) J Physiol , vol.495 , pp. 319
    • Oshimi, Y.1    Oshimi, K.2    Miyazaki, S.3
  • 36
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A (1996) Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271:12687
    • (1996) J Biol Chem , vol.271 , pp. 12687
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 38
    • 0019423896 scopus 로고
    • Transfer of cyclophosphamide-treated mice of natural killer cells and in vivo natural reactivity against tumors
    • Riccardi C, Barlozzari CT, Santoni A, Herberman RB, Cesarini C (1981) Transfer of cyclophosphamide-treated mice of natural killer cells and in vivo natural reactivity against tumors. J Immunol 126:1284
    • (1981) J Immunol , vol.126 , pp. 1284
    • Riccardi, C.1    Barlozzari, C.T.2    Santoni, A.3    Herberman, R.B.4    Cesarini, C.5
  • 39
    • 0035723884 scopus 로고    scopus 로고
    • Interleukin 2 and interleukin 15 differentially predispose natural killer cells to apoptosis mediated by endothelial and tumour cells
    • Rodella L, Zamai L, Rezzani R, Artico M, Peri G, Falconi M, Facchini A, Pelusi G, Vitale M (2001) Interleukin 2 and interleukin 15 differentially predispose natural killer cells to apoptosis mediated by endothelial and tumour cells. Br J Haematol 115:442
    • (2001) Br J Haematol , vol.115 , pp. 442
    • Rodella, L.1    Zamai, L.2    Rezzani, R.3    Artico, M.4    Peri, G.5    Falconi, M.6    Facchini, A.7    Pelusi, G.8    Vitale, M.9
  • 40
    • 0029066512 scopus 로고
    • FAP-1: A protein tyrosine phosphatase that associates with Fas
    • Sato T, Irie S, Kitada S, Reed JC (1995) FAP-1: a protein tyrosine phosphatase that associates with Fas. Science 268:411
    • (1995) Science , vol.268 , pp. 411
    • Sato, T.1    Irie, S.2    Kitada, S.3    Reed, J.C.4
  • 41
    • 0035881578 scopus 로고    scopus 로고
    • A central role for death-receptor-mediated apoptosis in the rejection of tumors by NK cells
    • Screpanti V, Wallin RPA, Ljunggren HG, Grandien A (2001) A central role for death-receptor-mediated apoptosis in the rejection of tumors by NK cells. J Immunol 167:2068
    • (2001) J Immunol , vol.167 , pp. 2068
    • Screpanti, V.1    Wallin, R.P.A.2    Ljunggren, H.G.3    Grandien, A.4
  • 42
    • 0026532606 scopus 로고
    • A natural killer cell granule protein that induces DNA fragmentation and apoptosis
    • Shi L, Kraut RP, Aebersold R, Greenberg AH (1992) A natural killer cell granule protein that induces DNA fragmentation and apoptosis. J Exp Med 175:553
    • (1992) J Exp Med , vol.175 , pp. 553
    • Shi, L.1    Kraut, R.P.2    Aebersold, R.3    Greenberg, A.H.4
  • 43
  • 44
    • 0035088926 scopus 로고    scopus 로고
    • Effect of interferon-γ on the susceptibility to Fas (CD95/APO-1)-mediated cell death in human hepatoma cells
    • Shin EC, Shin WC, Choi Y, Kim H, Park JH, Kim S (2001) Effect of interferon-γ on the susceptibility to Fas (CD95/APO-1)-mediated cell death in human hepatoma cells. Cancer Immunol Immunother 50:23
    • (2001) Cancer Immunol Immunother , vol.50 , pp. 23
    • Shin, E.C.1    Shin, W.C.2    Choi, Y.3    Kim, H.4    Park, J.H.5    Kim, S.6
  • 45
    • 0037204818 scopus 로고    scopus 로고
    • Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin
    • Shin EC, Seong YR, Kim CH, Kim H, Ahn YS, Kim K, Kim SJ, Hong SS, Park JH (2002) Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin. Exp Mol Med 34:114
    • (2002) Exp Mol Med , vol.34 , pp. 114
    • Shin, E.C.1    Seong, Y.R.2    Kim, C.H.3    Kim, H.4    Ahn, Y.S.5    Kim, K.6    Kim, S.J.7    Hong, S.S.8    Park, J.H.9
  • 46
    • 0028952301 scopus 로고
    • Granzymes: Exogenous proteinases that induce target cell apoptosis
    • Smyth MJ, Trapani JA (1995) Granzymes: exogenous proteinases that induce target cell apoptosis. Immunol Today 16:202
    • (1995) Immunol Today , vol.16 , pp. 202
    • Smyth, M.J.1    Trapani, J.A.2
  • 47
    • 0020369550 scopus 로고
    • Depressed natural killer cell activity in patients with hepatocellular carcinoma
    • Son K, Kew M, Rabson AR (1982) Depressed natural killer cell activity in patients with hepatocellular carcinoma. Cancer 50:2820
    • (1982) Cancer , vol.50 , pp. 2820
    • Son, K.1    Kew, M.2    Rabson, A.R.3
  • 48
    • 0035137696 scopus 로고    scopus 로고
    • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
    • Takeda K, Hayakawa Y, Smyth MJ, Kayagaki N, Yamaguchi N, Kakuta S, Iwakura Y, Yagita H, Okumura K (2001) Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med 7:94
    • (2001) Nat Med , vol.7 , pp. 94
    • Takeda, K.1    Hayakawa, Y.2    Smyth, M.J.3    Kayagaki, N.4    Yamaguchi, N.5    Kakuta, S.6    Iwakura, Y.7    Yagita, H.8    Okumura, K.9
  • 49
    • 0032127376 scopus 로고    scopus 로고
    • Natural killer cell activity in patients with hepatocellular carcinoma: A new prognostic indicator after hepatectomy
    • Taketomi A, Shimada M, Shirabe K, Kajiyama K, Gion T, Sugimachi K (1998) Natural killer cell activity in patients with hepatocellular carcinoma: a new prognostic indicator after hepatectomy. Cancer 83:58
    • (1998) Cancer , vol.83 , pp. 58
    • Taketomi, A.1    Shimada, M.2    Shirabe, K.3    Kajiyama, K.4    Gion, T.5    Sugimachi, K.6
  • 50
    • 0024792513 scopus 로고
    • Biology of natural killer cells
    • Trinchieri G (1989) Biology of natural killer cells. Adv Immunol 47:187
    • (1989) Adv Immunol , vol.47 , pp. 187
    • Trinchieri, G.1
  • 55
    • 0028812719 scopus 로고
    • The role of natural killer cells in immune surveillance of cancer
    • Whiteside TL, Herberman RB (1995) The role of natural killer cells in immune surveillance of cancer. Curr Opin Immunol 7:704
    • (1995) Curr Opin Immunol , vol.7 , pp. 704
    • Whiteside, T.L.1    Herberman, R.B.2
  • 61
    • 0024592017 scopus 로고
    • Killing of target cells by lymphocytes: A mechanistic view
    • Young JD (1989) Killing of target cells by lymphocytes: a mechanistic view. Physiol Rev 69:250
    • (1989) Physiol Rev , vol.69 , pp. 250
    • Young, J.D.1
  • 62
    • 0032447111 scopus 로고    scopus 로고
    • NK-cell-mediated cytotoxicity: Differential use of Trail and Fas ligand by immature and mature primary human NK cells
    • Zamai L, Ahmad M, Bennett IM, Azzoni L, Alnemri ES, Perussia B (1998) NK-cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells. J Exp Med 188:2375
    • (1998) J Exp Med , vol.188 , pp. 2375
    • Zamai, L.1    Ahmad, M.2    Bennett, I.M.3    Azzoni, L.4    Alnemri, E.S.5    Perussia, B.6
  • 63
    • 0026085649 scopus 로고
    • Cytolytic lymphocytes induce both apoptosis and necrosis in target cells
    • Zychlinsky A, Zheng LM, Liu CC, Young JD (1991) Cytolytic lymphocytes induce both apoptosis and necrosis in target cells. J Immunol 146:393
    • (1991) J Immunol , vol.146 , pp. 393
    • Zychlinsky, A.1    Zheng, L.M.2    Liu, C.C.3    Young, J.D.4


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