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Volumn 7, Issue 1, 2017, Pages 41-52

Phosphodiesterase-5 inhibition suppresses colonic inflammation-induced tumorigenesis via blocking the recruitment of MDSC

Author keywords

Colitis; Colon cancer; MDSC; PDE 5; Sildenafil

Indexed keywords

PHOSPHODIESTERASE V; SILDENAFIL;

EID: 85009914916     PISSN: None     EISSN: 21566976     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (72)

References (33)
  • 3
    • 84907990586 scopus 로고    scopus 로고
    • Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages
    • Hsu DS, Wang HJ, Tai SK, Chou CH, Hsieh CH, Chiu PH, Chen NJ and Yang MH. Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages. Cancer Cell 2014; 26: 534-548.
    • (2014) Cancer Cell , vol.26 , pp. 534-548
    • Hsu, D.S.1    Wang, H.J.2    Tai, S.K.3    Chou, C.H.4    Hsieh, C.H.5    Chiu, P.H.6    Chen, N.J.7    Yang, M.H.8
  • 4
    • 84898540767 scopus 로고    scopus 로고
    • Dual function of p38alpha MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival
    • Gupta J, del Barco Barrantes I, Igea A, Sakellariou S, Pateras IS, Gorgoulis VG and Nebreda AR. Dual function of p38alpha MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival. Cancer Cell 2014; 25: 484-500.
    • (2014) Cancer Cell , vol.25 , pp. 484-500
    • Gupta, J.1    del Barco Barrantes, I.2    Igea, A.3    Sakellariou, S.4    Pateras, I.S.5    Gorgoulis, V.G.6    Nebreda, A.R.7
  • 6
    • 79953750882 scopus 로고    scopus 로고
    • Che-mokines and cancer: a fatal attraction
    • Bonecchi R, Locati M and Mantovani A. Che-mokines and cancer: a fatal attraction. Cancer Cell 2011; 19: 434-435.
    • (2011) Cancer Cell , vol.19 , pp. 434-435
    • Bonecchi, R.1    Locati, M.2    Mantovani, A.3
  • 7
    • 58649100056 scopus 로고    scopus 로고
    • Inflammation and cancer: IL-6 and STAT3 complete the link
    • Bromberg J and Wang TC. Inflammation and cancer: IL-6 and STAT3 complete the link. Cancer Cell 2009; 15: 79-80.
    • (2009) Cancer Cell , vol.15 , pp. 79-80
    • Bromberg, J.1    Wang, T.C.2
  • 8
    • 0027987327 scopus 로고
    • Ulcerative colitis and Crohn's disease: a comparison of the colorectal cancer risk in extensive colitis
    • Gillen CD, Walmsley RS, Prior P, Andrews HA and Allan RN. Ulcerative colitis and Crohn's disease: a comparison of the colorectal cancer risk in extensive colitis. Gut 1994; 35: 1590-1592.
    • (1994) Gut , vol.35 , pp. 1590-1592
    • Gillen, C.D.1    Walmsley, R.S.2    Prior, P.3    Andrews, H.A.4    Allan, R.N.5
  • 11
    • 73149104650 scopus 로고    scopus 로고
    • Sulindac sulfide selectively inhibits growth and indu-ces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G
    • Tinsley HN, Gary BD, Keeton AB, Zhang W, Abadi AH, Reynolds RC and Piazza GA. Sulindac sulfide selectively inhibits growth and indu-ces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G. Mol Cancer Ther 2009; 8: 3331-3340.
    • (2009) Mol Cancer Ther , vol.8 , pp. 3331-3340
    • Tinsley, H.N.1    Gary, B.D.2    Keeton, A.B.3    Zhang, W.4    Abadi, A.H.5    Reynolds, R.C.6    Piazza, G.A.7
  • 13
    • 84856078223 scopus 로고    scopus 로고
    • Preconditioning by phosphodiesterase-5 inhibition improves therapeutic efficacy of adipose-derived stem cells follow-ing myocardial infarction in mice
    • Hoke NN, Salloum FN, Kass DA, Das A and Kukreja RC. Preconditioning by phosphodiesterase-5 inhibition improves therapeutic efficacy of adipose-derived stem cells follow-ing myocardial infarction in mice. Stem Cells 2012; 30: 326-335.
    • (2012) Stem Cells , vol.30 , pp. 326-335
    • Hoke, N.N.1    Salloum, F.N.2    Kass, D.A.3    Das, A.4    Kukreja, R.C.5
  • 15
    • 84887950782 scopus 로고    scopus 로고
    • The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension
    • Fan YF, Zhang R, Jiang X, Wen L, Wu DC, Liu D, Yuan P, Wang YL and Jing ZC. The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension. Cardiovasc Res 2013; 99: 395-403.
    • (2013) Cardiovasc Res , vol.99 , pp. 395-403
    • Fan, Y.F.1    Zhang, R.2    Jiang, X.3    Wen, L.4    Wu, D.C.5    Liu, D.6    Yuan, P.7    Wang, Y.L.8    Jing, Z.C.9
  • 16
    • 84960802321 scopus 로고    scopus 로고
    • Safety and efficacy of intraurethral alprostadil in patients with erectile dysfunction refractory to treatment using phosphodiesterase-5 inhibitors
    • Garrido Abad P, Sinues Ojas B, Martinez Blazquez L, Conde Caturla P and Fernandez Arjona M. Safety and efficacy of intraurethral alprostadil in patients with erectile dysfunction refractory to treatment using phosphodiesterase-5 inhibitors. Actas Urol Esp 2015; 39: 635-640.
    • (2015) Actas Urol Esp , vol.39 , pp. 635-640
    • Garrido Abad, P.1    Sinues Ojas, B.2    Martinez Blazquez, L.3    Conde Caturla, P.4    Fernandez Arjona, M.5
  • 17
    • 84934892621 scopus 로고    scopus 로고
    • Resveratrol and sildenafil synergistically improve diabetes-associated erectile dysfunction in streptozotocin-induced diabetic rats
    • Bai Y and An R. Resveratrol and sildenafil synergistically improve diabetes-associated erectile dysfunction in streptozotocin-induced diabetic rats. Life Sci 2015; 135: 43-48.
    • (2015) Life Sci , vol.135 , pp. 43-48
    • Bai, Y.1    An, R.2
  • 20
    • 66549098452 scopus 로고    scopus 로고
    • The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat
    • Iseri SO, Ersoy Y, Ercan F, Yuksel M, Atukeren P, Gumustas K and Alican I. The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat. J Gastroenterol Hepatol 2009; 24: 1142-1148.
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 1142-1148
    • Iseri, S.O.1    Ersoy, Y.2    Ercan, F.3    Yuksel, M.4    Atukeren, P.5    Gumustas, K.6    Alican, I.7
  • 23
    • 34548162712 scopus 로고    scopus 로고
    • An in-ducible mouse model of colon carcinogene-sis for the analysis of sporadic and inflam-mation-driven tumor progression
    • Neufert C, Becker C and Neurath MF. An in-ducible mouse model of colon carcinogene-sis for the analysis of sporadic and inflam-mation-driven tumor progression. Nat Protoc 2007; 2: 1998-2004.
    • (2007) Nat Protoc , vol.2 , pp. 1998-2004
    • Neufert, C.1    Becker, C.2    Neurath, M.F.3
  • 24
    • 38449084962 scopus 로고    scopus 로고
    • Isolation and sub-sequent analysis of murine lamina propria mononuclear cells from colonic tissue
    • Weigmann B, Tubbe I, Seidel D, Nicolaev A, Becker C and Neurath MF. Isolation and sub-sequent analysis of murine lamina propria mononuclear cells from colonic tissue. Nat Protoc 2007; 2: 2307-2311.
    • (2007) Nat Protoc , vol.2 , pp. 2307-2311
    • Weigmann, B.1    Tubbe, I.2    Seidel, D.3    Nicolaev, A.4    Becker, C.5    Neurath, M.F.6
  • 27
    • 18444366205 scopus 로고    scopus 로고
    • Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells
    • Zhu B, Vemavarapu L, Thompson WJ and Strada SJ. Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells. J Cell Biochem 2005; 94: 336-350.
    • (2005) J Cell Biochem , vol.94 , pp. 336-350
    • Zhu, B.1    Vemavarapu, L.2    Thompson, W.J.3    Strada, S.J.4
  • 30
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI and Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9: 162-174.
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 31
    • 84957432656 scopus 로고    scopus 로고
    • G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers
    • Li W, Zhang X, Chen Y, Xie Y, Liu J, Feng Q, Wang Y, Yuan W and Ma J. G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers. Protein Cell 2016; 7: 130-140.
    • (2016) Protein Cell , vol.7 , pp. 130-140
    • Li, W.1    Zhang, X.2    Chen, Y.3    Xie, Y.4    Liu, J.5    Feng, Q.6    Wang, Y.7    Yuan, W.8    Ma, J.9
  • 32
    • 84888227624 scopus 로고    scopus 로고
    • Myeloid-de-rived suppressor cells in the inflammatory bowel diseases
    • Ostanin DV and Bhattacharya D. Myeloid-de-rived suppressor cells in the inflammatory bowel diseases. Inflamm Bowel Dis 2013; 19: 2468-2477.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 2468-2477
    • Ostanin, D.V.1    Bhattacharya, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.