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Volumn 193, Issue 2, 2015, Pages 667-674

Effectiveness of sildenafil and U-74389G in a rat model of colitis

Author keywords

Lazaroid U 74389G; MDA; Sildenafil; TNBS induced colitis; TNF

Indexed keywords

21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]PREGNA 1,4,9(11) TRIENE 3,20 DIONE; MALONALDEHYDE; SILDENAFIL; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; PHOSPHODIESTERASE V INHIBITOR; PIPERAZINE DERIVATIVE; PREGNANE DERIVATIVE; PURINE DERIVATIVE; SULFONE;

EID: 84917679649     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2014.08.064     Document Type: Article
Times cited : (22)

References (32)
  • 1
    • 34248136340 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Clinical aspects and established and evolving therapies
    • D.C. Baumgart, and W.J. Sandborn Inflammatory bowel disease: clinical aspects and established and evolving therapies Lancet 369 2007 1641
    • (2007) Lancet , vol.369 , pp. 1641
    • Baumgart, D.C.1    Sandborn, W.J.2
  • 2
    • 84888212964 scopus 로고    scopus 로고
    • Innate and adaptive immunity in inflammatory bowel diseases
    • S. Foersch, M.J. Waldner, and M.F. Neurath Innate and adaptive immunity in inflammatory bowel diseases Dig Dis 31 2013 317
    • (2013) Dig Dis , vol.31 , pp. 317
    • Foersch, S.1    Waldner, M.J.2    Neurath, M.F.3
  • 3
    • 84867726955 scopus 로고    scopus 로고
    • Animal models of inflammatory bowel diseases: Illuminating the pathogenesis of colitis, ileitis and cancer
    • M.F. Neurath Animal models of inflammatory bowel diseases: illuminating the pathogenesis of colitis, ileitis and cancer Dig Dis 30 Suppl 1 2012 91
    • (2012) Dig Dis , vol.30 , pp. 91
    • Neurath, M.F.1
  • 4
    • 0029002215 scopus 로고
    • Improved survival and reversal of endothelial dysfunction by the 21-aminosteroid U-74389G in splanchnic ischaemia-reperfusion injury in the rat
    • F. Squadrito, D. Altavilla, and L. Ammendolia Improved survival and reversal of endothelial dysfunction by the 21-aminosteroid U-74389G in splanchnic ischaemia-reperfusion injury in the rat Br J Pharmacol 115 1995 395
    • (1995) Br J Pharmacol , vol.115 , pp. 395
    • Squadrito, F.1    Altavilla, D.2    Ammendolia, L.3
  • 5
    • 17344378694 scopus 로고    scopus 로고
    • Protective effects of lazaroid U74389G on intestinal graft after heterotopic small bowel transplantation in rats
    • J. De Oca, S. Cuadrado, and J. Vallet Protective effects of lazaroid U74389G on intestinal graft after heterotopic small bowel transplantation in rats J Surg Res 75 1998 18
    • (1998) J Surg Res , vol.75 , pp. 18
    • De Oca, J.1    Cuadrado, S.2    Vallet, J.3
  • 6
    • 80052036279 scopus 로고    scopus 로고
    • The effect of phosphodiesterase-5 inhibition by sildenafil citrate on inflammation and apoptosis in rat experimental colitis
    • B. Karakoyun, U. Uslu, and F. Ercan The effect of phosphodiesterase-5 inhibition by sildenafil citrate on inflammation and apoptosis in rat experimental colitis Life Sci 89 2011 402
    • (2011) Life Sci , vol.89 , pp. 402
    • Karakoyun, B.1    Uslu, U.2    Ercan, F.3
  • 7
    • 66549098452 scopus 로고    scopus 로고
    • The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat
    • S.O. Iseri, Y. Ersoy, and F. Ercan The effect of sildenafil, a phosphodiesterase-5 inhibitor, on acetic acid-induced colonic inflammation in the rat J Gastroenterol Hepatol 24 2009 1142
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 1142
    • Iseri, S.O.1    Ersoy, Y.2    Ercan, F.3
  • 8
    • 82655171771 scopus 로고    scopus 로고
    • Animal models of inflammatory bowel disease
    • A. Mizogushi Animal models of inflammatory bowel disease Prog Mol Biol Transl Sci 105 2012 263
    • (2012) Prog Mol Biol Transl Sci , vol.105 , pp. 263
    • Mizogushi, A.1
  • 10
  • 12
    • 0344467399 scopus 로고    scopus 로고
    • Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats
    • W.G. Dong, S.P. Liu, B.P. Yu, D.F. Wu, H.S. Luo, and J.P. Yu Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats World J Gastroenterol 9 2003 2533
    • (2003) World J Gastroenterol , vol.9 , pp. 2533
    • Dong, W.G.1    Liu, S.P.2    Yu, B.P.3    Wu, D.F.4    Luo, H.S.5    Yu, J.P.6
  • 13
    • 0033849872 scopus 로고    scopus 로고
    • A reproducible grading scale for histological assessment of inflammation in ulcerative colitis
    • K. Geboes, R. Riddell, A. Ost, B. Jensfelt, T. Persson, and R. Löfberg A reproducible grading scale for histological assessment of inflammation in ulcerative colitis Gut 47 2000 404
    • (2000) Gut , vol.47 , pp. 404
    • Geboes, K.1    Riddell, R.2    Ost, A.3    Jensfelt, B.4    Persson, T.5    Löfberg, R.6
  • 14
    • 0142229899 scopus 로고    scopus 로고
    • Effect of U-74389G (21-lazaroid) on intestinal recovery after acute mesenteric ischemia and reperfusion in rats
    • I. Andreadou, D. Poussios, and A. Papalois Effect of U-74389G (21-lazaroid) on intestinal recovery after acute mesenteric ischemia and reperfusion in rats In Vivo 17 2003 463
    • (2003) Vivo , vol.17 , pp. 463
    • Andreadou, I.1    Poussios, D.2    Papalois, A.3
  • 15
    • 25644449484 scopus 로고    scopus 로고
    • Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis
    • J.H. Li, J.P. Yu, and H.G. Yu Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis Mediators Inflamm 2005 2005 185
    • (2005) Mediators Inflamm , vol.2005 , pp. 185
    • Li, J.H.1    Yu, J.P.2    Yu, H.G.3
  • 16
    • 65349172410 scopus 로고    scopus 로고
    • Biologic targeting in the treatment of inflammatory bowel diseases
    • M. Bosani, S. Ardizzone, and G.B. Porro Biologic targeting in the treatment of inflammatory bowel diseases Biologics 3 2009 77
    • (2009) Biologics , vol.3 , pp. 77
    • Bosani, M.1    Ardizzone, S.2    Porro, G.B.3
  • 17
    • 73349141744 scopus 로고    scopus 로고
    • Proinflammatory cytokines suppress the expression level of protease-activated receptor-2 through the induction of iNOS in rat colon
    • A. Horie, K. Nagai, S. Ohkura, T. Ohama, H. Komatsu, and K. Sato Proinflammatory cytokines suppress the expression level of protease-activated receptor-2 through the induction of iNOS in rat colon J Vet Med Sci 71 2009 1609
    • (2009) J Vet Med Sci , vol.71 , pp. 1609
    • Horie, A.1    Nagai, K.2    Ohkura, S.3    Ohama, T.4    Komatsu, H.5    Sato, K.6
  • 18
    • 77956414882 scopus 로고    scopus 로고
    • Infliximab in ulcerative colitis
    • A. Levin, and O. Shibolet Infliximab in ulcerative colitis Biologics 2 2008 379
    • (2008) Biologics , vol.2 , pp. 379
    • Levin, A.1    Shibolet, O.2
  • 19
    • 59149097248 scopus 로고    scopus 로고
    • Therapeutic effect of lecithinized superoxide dismutase against colitis
    • T. Ishihara, K. Tanaka, and Y. Tasaka Therapeutic effect of lecithinized superoxide dismutase against colitis J Pharmacol Exp Ther 328 2009 152
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 152
    • Ishihara, T.1    Tanaka, K.2    Tasaka, Y.3
  • 20
    • 33749508679 scopus 로고    scopus 로고
    • Effects of Ginkgo biloba extract on inflammatory mediators (SOD, MDA, TNF-alpha, NF-kappaBp65, IL-6) in TNBS-induced colitis in rats
    • Y.H. Zhou, J.P. Yu, and Y.F. Liu Effects of Ginkgo biloba extract on inflammatory mediators (SOD, MDA, TNF-alpha, NF-kappaBp65, IL-6) in TNBS-induced colitis in rats Mediators Inflamm 2006 2006 92642
    • (2006) Mediators Inflamm , vol.2006 , pp. 92642
    • Zhou, Y.H.1    Yu, J.P.2    Liu, Y.F.3
  • 21
    • 0034893711 scopus 로고    scopus 로고
    • Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3-(Aminomethyl)benzyl]acetamidine
    • E. Kankuri, K. Vaali, and R. Knowles Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3-(Aminomethyl)benzyl]acetamidine J Pharmacol Exp Ther 298 2001 1128
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 1128
    • Kankuri, E.1    Vaali, K.2    Knowles, R.3
  • 22
    • 0027478882 scopus 로고
    • Nitric oxide in ulcerative colitis
    • M. Guslandi Nitric oxide in ulcerative colitis Lancet 341 1993 905
    • (1993) Lancet , vol.341 , pp. 905
    • Guslandi, M.1
  • 23
    • 0032938256 scopus 로고    scopus 로고
    • Nitric oxide. III. A molecular prelude to intestinal inflammation
    • M.J. Miller, and M. Sandoval Nitric oxide. III. A molecular prelude to intestinal inflammation Am J Physiol 276 1999 G795
    • (1999) Am J Physiol , vol.276 , pp. 795
    • Miller, M.J.1    Sandoval, M.2
  • 24
    • 33644989275 scopus 로고    scopus 로고
    • Cyclical upregulated iNOS and long-term downregulated nNOS are the bases for relapse and quiescent phases in a rat model of IBD
    • M. Porras, M.T. Martín, R. Torres, and P. Vergara Cyclical upregulated iNOS and long-term downregulated nNOS are the bases for relapse and quiescent phases in a rat model of IBD Am J Physiol Gastrointest Liver Physiol 290 2006 G423
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , pp. 423
    • Porras, M.1    Martín, M.T.2    Torres, R.3    Vergara, P.4
  • 25
    • 0033060060 scopus 로고    scopus 로고
    • The lazaroid, U-74389G, inhibits inducible nitric oxide synthase activity, reverses vascular failure and protects against endotoxin shock
    • D. Altavilla, F. Squadrito, and G.M. Campo The lazaroid, U-74389G, inhibits inducible nitric oxide synthase activity, reverses vascular failure and protects against endotoxin shock Eur J Pharmacol 369 1999 49
    • (1999) Eur J Pharmacol , vol.369 , pp. 49
    • Altavilla, D.1    Squadrito, F.2    Campo, G.M.3
  • 26
    • 84984564151 scopus 로고    scopus 로고
    • Specific role of neutrophil inducible nitric oxide synthase in murine sepsis-induced lung injury in vivo
    • L. Wang, R. Taneja, H.M. Razavi, C. Law, C. Gillis, and S. Mehta Specific role of neutrophil inducible nitric oxide synthase in murine sepsis-induced lung injury in vivo Shock 37 2012 539
    • (2012) Shock , vol.37 , pp. 539
    • Wang, L.1    Taneja, R.2    Razavi, H.M.3    Law, C.4    Gillis, C.5    Mehta, S.6
  • 27
    • 9944233058 scopus 로고    scopus 로고
    • "nitric oxide in inflammatory bowel disease: A universal messenger in an unsolved puzzle"
    • G. Kolios, V. Valatas, and S.G. Ward "Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle" Immunology 113 2004 427
    • (2004) Immunology , vol.113 , pp. 427
    • Kolios, G.1    Valatas, V.2    Ward, S.G.3
  • 28
    • 84858026509 scopus 로고    scopus 로고
    • Sildenafil attenuates TNBS-induced colitis in rats: Possible involvement of cGMP and KATP channels
    • G. Fakhfouria, R. Rahimianb, and S. Hashemic Sildenafil attenuates TNBS-induced colitis in rats: possible involvement of cGMP and KATP channels Fundam Clin Pharmacol 26 2012 190
    • (2012) Fundam Clin Pharmacol , vol.26 , pp. 190
    • Fakhfouria, G.1    Rahimianb, R.2    Hashemic, S.3
  • 29
    • 84900543763 scopus 로고    scopus 로고
    • The effect of U-74389G on pancreas ischemia-reperfusion injury in a swine model
    • D.T. Chrysikos, T.N. Sergentanis, and F. Zagouri The effect of U-74389G on pancreas ischemia-reperfusion injury in a swine model J Surg Res 187 2014 450
    • (2014) J Surg Res , vol.187 , pp. 450
    • Chrysikos, D.T.1    Sergentanis, T.N.2    Zagouri, F.3
  • 30
    • 57149093461 scopus 로고    scopus 로고
    • The effect of U-74389G on liver recovery after liver ischemia-reperfusion injury in a swine model
    • A.K. Tsaroucha, A. Papapois, and S. Vernadakis The effect of U-74389G on liver recovery after liver ischemia-reperfusion injury in a swine model J Surg Res 151 2009 10
    • (2009) J Surg Res , vol.151 , pp. 10
    • Tsaroucha, A.K.1    Papapois, A.2    Vernadakis, S.3
  • 31
    • 80052545378 scopus 로고    scopus 로고
    • Changes in arterial blood flow of free flaps after the administration of sildenafil in swine
    • A. Gravvanis, A. Papalois, and I. Delikonstantinou Changes in arterial blood flow of free flaps after the administration of sildenafil in swine Microsurgery 31 2011 465
    • (2011) Microsurgery , vol.31 , pp. 465
    • Gravvanis, A.1    Papalois, A.2    Delikonstantinou, I.3
  • 32
    • 46749127004 scopus 로고    scopus 로고
    • DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
    • L.B. Meira, J.M. Bugni, and S.L. Green DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice J Clin Invest 118 2008 2516
    • (2008) J Clin Invest , vol.118 , pp. 2516
    • Meira, L.B.1    Bugni, J.M.2    Green, S.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.