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Volumn 8, Issue 3, 2015, Pages 533-541

Effects of Sildenafil on Ventricular and Vascular Function in Heart Failure with Preserved Ejection Fraction

Author keywords

diastolic heart failure; heart failure; vascular function; ventricular function

Indexed keywords

PLACEBO; SILDENAFIL; PHOSPHODIESTERASE V INHIBITOR; PIPERAZINE DERIVATIVE; PURINE DERIVATIVE; SULFONAMIDE; VASODILATOR AGENT;

EID: 84942936387     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.114.001915     Document Type: Article
Times cited : (60)

References (34)
  • 1
    • 33746088001 scopus 로고    scopus 로고
    • Trends in prevalence and outcome of heart failure with preserved ejection fraction
    • Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, Redfield MM. Trends in prevalence and outcome of heart failure with preserved ejection fraction. N Engl J Med. 2006;355:251-259. doi: 10.1056/NEJMoa052256.
    • (2006) N Engl J Med , vol.355 , pp. 251-259
    • Owan, T.E.1    Hodge, D.O.2    Herges, R.M.3    Jacobsen, S.J.4    Roger, V.L.5    Redfield, M.M.6
  • 3
    • 67650547206 scopus 로고    scopus 로고
    • Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency
    • Phan TT, Abozguia K, Nallur Shivu G, Mahadevan G, Ahmed I, Williams L, Dwivedi G, Patel K, Steendijk P, Ashrafian H, Henning A, Frenneaux M. Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency. J Am Coll Cardiol. 2009;54:402-409. doi: 10.1016/j.jacc.2009.05.012.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 402-409
    • Phan, T.T.1    Abozguia, K.2    Nallur Shivu, G.3    Mahadevan, G.4    Ahmed, I.5    Williams, L.6    Dwivedi, G.7    Patel, K.8    Steendijk, P.9    Ashrafian, H.10    Henning, A.11    Frenneaux, M.12
  • 4
    • 67449092157 scopus 로고    scopus 로고
    • The pathophysiology of heart failure with normal ejection fraction: Exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion
    • Tan YT, Wenzelburger F, Lee E, Heatlie G, Leyva F, Patel K, Frenneaux M, Sanderson JE. The pathophysiology of heart failure with normal ejection fraction: exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion. J Am Coll Cardiol. 2009;54:36-46. doi: 10.1016/j.jacc.2009.03.037.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 36-46
    • Tan, Y.T.1    Wenzelburger, F.2    Lee, E.3    Heatlie, G.4    Leyva, F.5    Patel, K.6    Frenneaux, M.7    Sanderson, J.E.8
  • 5
    • 77957907689 scopus 로고    scopus 로고
    • Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction
    • Borlaug BA, Nishimura RA, Sorajja P, Lam CS, Redfield MM. Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction. Circ Heart Fail. 2010;3:588-595. doi: 10.1161/CIRCHEARTFAILURE.109.930701.
    • (2010) Circ Heart Fail , vol.3 , pp. 588-595
    • Borlaug, B.A.1    Nishimura, R.A.2    Sorajja, P.3    Lam, C.S.4    Redfield, M.M.5
  • 6
    • 77956324154 scopus 로고    scopus 로고
    • Hemodynamic basis of exercise limitation in patients with heart failure and normal ejection fraction
    • Maeder MT, Thompson BR, Brunner-La Rocca HP, Kaye DM. Hemodynamic basis of exercise limitation in patients with heart failure and normal ejection fraction. J Am Coll Cardiol. 2010;56:855-863. doi: 10.1016/j.jacc.2010.04.040.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 855-863
    • Maeder, M.T.1    Thompson, B.R.2    Brunner-La Rocca, H.P.3    Kaye, D.M.4
  • 7
    • 79960039049 scopus 로고    scopus 로고
    • Determinants of exercise intolerance in elderly heart failure patients with preserved ejection fraction
    • Haykowsky MJ, Brubaker PH, John JM, Stewart KP, Morgan TM, Kitzman DW. Determinants of exercise intolerance in elderly heart failure patients with preserved ejection fraction. J Am Coll Cardiol. 2011;58:265-274. doi: 10.1016/j.jacc.2011.02.055.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 265-274
    • Haykowsky, M.J.1    Brubaker, P.H.2    John, J.M.3    Stewart, K.P.4    Morgan, T.M.5    Kitzman, D.W.6
  • 8
    • 84906937269 scopus 로고    scopus 로고
    • The pathophysiology of heart failure with preserved ejection fraction
    • Borlaug BA. The pathophysiology of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2014;11:507-515. doi: 10.1038/nrcardio.2014.83.
    • (2014) Nat Rev Cardiol , vol.11 , pp. 507-515
    • Borlaug, B.A.1
  • 9
    • 79952829685 scopus 로고    scopus 로고
    • Heart failure with preserved ejection fraction: Pathophysiology, diagnosis, and treatment
    • Borlaug BA, Paulus WJ. Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment. Eur Heart J. 2011;32:670-679. doi: 10.1093/eurheartj/ehq426.
    • (2011) Eur Heart J , vol.32 , pp. 670-679
    • Borlaug, B.A.1    Paulus, W.J.2
  • 10
    • 84879748718 scopus 로고    scopus 로고
    • A novel paradigm for heart failure with preserved ejection fraction: Comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation
    • Paulus WJ, Tschöpe C. A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol. 2013;62:263-271. doi: 10.1016/j.jacc.2013.02.092.
    • (2013) J Am Coll Cardiol , vol.62 , pp. 263-271
    • Paulus, W.J.1    Tschöpe, C.2
  • 14
    • 79551580284 scopus 로고    scopus 로고
    • PDE5 inhibition with sildenafil improves left ventricular diastolic function, cardiac geometry, and clinical status in patients with stable systolic heart failure: Results of a 1-year, prospective, randomized, placebo-controlled study
    • Guazzi M, Vicenzi M, Arena R, Guazzi MD. PDE5 inhibition with sildenafil improves left ventricular diastolic function, cardiac geometry, and clinical status in patients with stable systolic heart failure: results of a 1-year, prospective, randomized, placebo-controlled study. Circ Heart Fail. 2011;4:8-17. doi: 10.1161/CIRCHEARTFAILURE.110.944694.
    • (2011) Circ Heart Fail , vol.4 , pp. 8-17
    • Guazzi, M.1    Vicenzi, M.2    Arena, R.3    Guazzi, M.D.4
  • 15
    • 36148948551 scopus 로고    scopus 로고
    • Long-term use of sildenafil in the therapeutic management of heart failure
    • Guazzi M, Samaja M, Arena R, Vicenzi M, Guazzi MD. Long-term use of sildenafil in the therapeutic management of heart failure. J Am Coll Cardiol. 2007;50:2136-2144. doi: 10.1016/j.jacc.2007.07.078.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 2136-2144
    • Guazzi, M.1    Samaja, M.2    Arena, R.3    Vicenzi, M.4    Guazzi, M.D.5
  • 16
    • 79960396933 scopus 로고    scopus 로고
    • Pulmonary hypertension in heart failure with preserved ejection fraction: A target of phosphodiesterase-5 inhibition in a 1-year study
    • Guazzi M, Vicenzi M, Arena R, Guazzi MD. Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study. Circulation. 2011;124:164-174. doi: 10.1161/CIRCULATIONAHA.110.983866.
    • (2011) Circulation , vol.124 , pp. 164-174
    • Guazzi, M.1    Vicenzi, M.2    Arena, R.3    Guazzi, M.D.4
  • 18
    • 84868651278 scopus 로고    scopus 로고
    • PhosphdiesteRasE-5 Inhibition to Improve Clinical Status and Exercise Capacity in Diastolic Heart Failure (RELAX) trial: Rationale and design
    • Heart Failure Clinical Research Network
    • Redfield MM, Borlaug BA, Lewis GD, Mohammed SF, Semigran MJ, Lewinter MM, Deswal A, Hernandez AF, Lee KL, Braunwald E; Heart Failure Clinical Research Network. PhosphdiesteRasE-5 Inhibition to Improve Clinical Status and Exercise Capacity in Diastolic Heart Failure (RELAX) trial: rationale and design. Circ Heart Fail. 2012;5:653-659. doi: 10.1161/CIRCHEARTFAILURE.112.969071.
    • (2012) Circ Heart Fail , vol.5 , pp. 653-659
    • Redfield, M.M.1    Borlaug, B.A.2    Lewis, G.D.3    Mohammed, S.F.4    Semigran, M.J.5    Lewinter, M.M.6    Deswal, A.7    Hernandez, A.F.8    Lee, K.L.9    Braunwald, E.10
  • 19
    • 29244432482 scopus 로고    scopus 로고
    • Recommendations for chamber quantification: A report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology
    • Chamber Quantification Writing Group; American Society of Echocardiography's Guidelines and Standards Committee; European Association of Echocardiography
    • Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, Picard MH, Roman MJ, Seward J, Shanewise JS, Solomon SD, Spencer KT, Sutton MS, Stewart WJ; Chamber Quantification Writing Group; American Society of Echocardiography's Guidelines and Standards Committee; European Association of Echocardiography. Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005;18:1440-1463. doi: 10.1016/j. echo.2005.10.005.
    • (2005) J Am Soc Echocardiogr , vol.18 , pp. 1440-1463
    • Lang, R.M.1    Bierig, M.2    Devereux, R.B.3    Flachskampf, F.A.4    Foster, E.5    Pellikka, P.A.6    Picard, M.H.7    Roman, M.J.8    Seward, J.9    Shanewise, J.S.10    Solomon, S.D.11    Spencer, K.T.12    Sutton, M.S.13    Stewart, W.J.14
  • 20
    • 27444439573 scopus 로고    scopus 로고
    • Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans
    • Borlaug BA, Melenovsky V, Marhin T, Fitzgerald P, Kass DA. Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans. Circulation. 2005;112:2642-2649. doi: 10.1161/CIRCULATIONAHA.105.540500.
    • (2005) Circulation , vol.112 , pp. 2642-2649
    • Borlaug, B.A.1    Melenovsky, V.2    Marhin, T.3    Fitzgerald, P.4    Kass, D.A.5
  • 21
    • 0028295432 scopus 로고
    • Ventricular systolic assessment in patients with dilated cardiomyopathy by preload-adjusted maximal power. Validation and noninvasive application
    • Sharir T, Feldman MD, Haber H, Feldman AM, Marmor A, Becker LC, Kass DA. Ventricular systolic assessment in patients with dilated cardiomyopathy by preload-adjusted maximal power. Validation and noninvasive application. Circulation. 1994;89:2045-2053.
    • (1994) Circulation , vol.89 , pp. 2045-2053
    • Sharir, T.1    Feldman, M.D.2    Haber, H.3    Feldman, A.M.4    Marmor, A.5    Becker, L.C.6    Kass, D.A.7
  • 22
    • 0031850498 scopus 로고    scopus 로고
    • Optimal preload adjustment of maximal ventricular power index varies with cardiac chamber size
    • Nakayama M, Chen CH, Nevo E, Fetics B, Wong E, Kass DA. Optimal preload adjustment of maximal ventricular power index varies with cardiac chamber size. Am Heart J. 1998;136:281-288. doi: 10.1053/hj.1998.v136.89584.
    • (1998) Am Heart J , vol.136 , pp. 281-288
    • Nakayama, M.1    Chen, C.H.2    Nevo, E.3    Fetics, B.4    Wong, E.5    Kass, D.A.6
  • 23
    • 34247201690 scopus 로고    scopus 로고
    • Cardiac structure and ventricular-vascular function in persons with heart failure and preserved ejection fraction from Olmsted County Minnesota
    • Lam CS, Roger VL, Rodeheffer RJ, Bursi F, Borlaug BA, Ommen SR, Kass DA, Redfield MM. Cardiac structure and ventricular-vascular function in persons with heart failure and preserved ejection fraction from Olmsted County, Minnesota. Circulation. 2007;115:1982-1990. doi: 10.1161/CIRCULATIONAHA.106.659763.
    • (2007) Circulation , vol.115 , pp. 1982-1990
    • Lam, C.S.1    Roger, V.L.2    Rodeheffer, R.J.3    Bursi, F.4    Borlaug, B.A.5    Ommen, S.R.6    Kass, D.A.7    Redfield, M.M.8
  • 25
    • 0033858827 scopus 로고    scopus 로고
    • Acute type 5 phosphodiesterase inhibition with sildenafil enhances flowmediated vasodilation in patients with chronic heart failure
    • Katz SD, Balidemaj K, Homma S, Wu H, Wang J, Maybaum S. Acute type 5 phosphodiesterase inhibition with sildenafil enhances flowmediated vasodilation in patients with chronic heart failure. J Am Coll Cardiol. 2000;36:845-851.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 845-851
    • Katz, S.D.1    Balidemaj, K.2    Homma, S.3    Wu, H.4    Wang, J.5    Maybaum, S.6
  • 26
    • 84871741739 scopus 로고    scopus 로고
    • Relationship of flow-mediated arterial dilation and exercise capacity in older patients with heart failure and preserved ejection fraction
    • Haykowsky MJ, Herrington DM, Brubaker PH, Morgan TM, Hundley WG, Kitzman DW. Relationship of flow-mediated arterial dilation and exercise capacity in older patients with heart failure and preserved ejection fraction. J Gerontol A Biol Sci Med Sci. 2013;68:161-167. doi: 10.1093/gerona/gls099.
    • (2013) J Gerontol A Biol Sci Med Sci , vol.68 , pp. 161-167
    • Haykowsky, M.J.1    Herrington, D.M.2    Brubaker, P.H.3    Morgan, T.M.4    Hundley, W.G.5    Kitzman, D.W.6
  • 29
    • 0042917516 scopus 로고    scopus 로고
    • Nitric oxide and cardiac function: Ten years after, and continuing
    • Massion PB, Feron O, Dessy C, Balligand JL. Nitric oxide and cardiac function: ten years after, and continuing. Circ Res. 2003;93:388-398. doi: 10.1161/01.RES.0000088351.58510.21.
    • (2003) Circ Res , vol.93 , pp. 388-398
    • Massion, P.B.1    Feron, O.2    Dessy, C.3    Balligand, J.L.4
  • 32
    • 0028844217 scopus 로고
    • Nitric oxide inhibits the positive inotropic response to beta-adrenergic stimulation in humans with left ventricular dysfunction
    • Hare JM, Loh E, Creager MA, Colucci WS. Nitric oxide inhibits the positive inotropic response to beta-adrenergic stimulation in humans with left ventricular dysfunction. Circulation. 1995;92:2198-2203.
    • (1995) Circulation , vol.92 , pp. 2198-2203
    • Hare, J.M.1    Loh, E.2    Creager, M.A.3    Colucci, W.S.4
  • 34
    • 72649099929 scopus 로고    scopus 로고
    • Caveat medicus! Pulmonary hypertension in the elderly: A word of caution
    • Boilson BA, Schirger JA, Borlaug BA. Caveat medicus! Pulmonary hypertension in the elderly: a word of caution. Eur J Heart Fail. 2010;12:89-93. doi: 10.1093/eurjhf/hfp171.
    • (2010) Eur J Heart Fail , vol.12 , pp. 89-93
    • Boilson, B.A.1    Schirger, J.A.2    Borlaug, B.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.