Safety and efficacy of intraurethral alprostadil in patients with erectile dysfunction refractory to treatment using phosphodiesterase-5 inhibitors;Eficacia y seguridad del alprostadil intrauretral en pacientes con disfunción eréctil refractarios al tratamiento mediante inhibidores de la 5-fosfodiesterasa

Actas Urologicas Espanolas

Volumn 39, Issue 10, 2015, Pages 635-640

  Garrido Abad, P ^a   Sinues Ojas B ^a   Martinez Blazquez L ^a   Conde Caturla, P ^a   Fernandez Arjona M ^a  

^a Refractive Surgeon at Clínica Baviera Madrid   (Spain)

Author keywords

Alprostadil; Erectile dysfunction; Intraurethral

Indexed keywords

PHOSPHODIESTERASE V INHIBITOR; PROSTAGLANDIN E1;

ADULT; AGED; ERECTILE DYSFUNCTION; HUMAN; MALE; MIDDLE AGED; QUESTIONNAIRE; RETROSPECTIVE STUDY; TREATMENT FAILURE; TREATMENT OUTCOME; URETHRA; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ALPROSTADIL; ERECTILE DYSFUNCTION; HUMANS; MALE; MIDDLE AGED; PHOSPHODIESTERASE 5 INHIBITORS; RETROSPECTIVE STUDIES; SURVEYS AND QUESTIONNAIRES; TREATMENT FAILURE; TREATMENT OUTCOME; URETHRA;

EID: 84960802321     PISSN: 02104806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.acuro.2015.04.007     Document Type: Article

References (26)

1. Hatzimouratidis K. Eardley I, Giuliano F, Moncada I, Salonia A. Guidelines on male sexual dysfunction: Erectile dysfunction and premature ejaculation. European Association of Urology 2015. [consultado 10 Ene 2015]. Disponible en: http://uroweb.org/guideline/male-sexual-dysfunction/
2. A. Martín Morales, P.R. Gutiérrez Hernández, F. Meijide Rico, J.L. Arrondo Arrondo, and C. Turbí Disla Efectividad y satisfacción con el tratamiento en pacientes con disfunción eréctil en España: Estudio EDOS Actas Urol Esp. 34 2010 356 364
3. I. Goldstein, J.M. Young, J. Fischer, K. Bangerter, T. Segerson, and T. Taylor Vardenafil a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: A multicenter double-blind placebo-controlled fixed-dose study Diabetes Care. 26 2003 777 783
4. D. Ziegler, F. Merfort, H. van Ahlen, A. Yassin, T. Reblin, and M. Neureither Efficacy and safety of flexible-dose vardenafil in men with type 1 diabetes and erectile dysfunction J Sex Med. 3 2006 883 891
5. V. Fonseca, A. Seftel, J. Denne, and P. Fredlund Impact of diabetes mellitus on the severity of erectile dysfunction and response to treatment: Analysis of data from tadalafil clinical trials Diabetologia. 47 2004 1914 1923
6. G.P. Zagaja, D.A. Mhoon, J.E. Aikens, and C.B. Brendler Sildenafil in the treatment of erectile dysfunction after radical prostatectomy Urology. 56 2000 631 634
7. H. Padma-Nathan, W.J.G. Hellstrom, F.E. Kaiser, R.F. Labasky, T. Lue, W.E. Nolten, and et al. Treatment of men with erectile dysfunction with transurethral alprostadil N Engl J Med. 336 1997 1 7
8. S.E. Althof, E.W. Corty, S.B. Levine, F. Levine, A.L. Burnett, K. McVary, and et al. EDITS: Development of questionnaires for evaluating satisfaction with treatments for erectile dysfunction Urology. 53 1999 793 799
9. Sun L, Peng FL, Yu ZL, Liu CL, Chen J. Combined sildenafil with vacuum erection device therapy in the management of diabetic men with erectile dysfunction after failure of first-line sildenafil monotherapy. Int J Urol. 2014;21(12):1263-1267. Doi: 10.1111/iju.12564. Epub 2014 Jul 14. Epub ahead of print.
10. K. Wolf-Maier, R.S. Cooper, J.R. Banegas, S. Giampaoli, H.W. Hense, M. Joffres, and et al. Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States JAMA. 289 2003 2363 2369
11. A. Nehra Erectile dysfunction and cardiovascular disease efficacy and safety of phosphodiesterase type 5 inhibitors in men with both conditions Mayo Clin Proc. 84 2009 139 148
12. J.P. Mulhall, T.J. Bivalacqua, and E.F. Becher Standard operating precedure for the preservation of erectile function outcomes after radical prostatectomy J Sex Med 10 2013 195 203
13. L.S. Marks, C. Duda, F.J. Dorey, M.L. Macairan, and P.B. Santos Treatment of erectile dysfunction with sildenafil Urology 53 1999 19 24
14. H. Van Ahlen, K. Wahle, W. Kupper, A. Yassin, T. Reblin, and M. Neureither Safety and efficacy of vardenafil, a selective phosphodiesterase 5 inhibitor, in patients with erectile dysfunction and arterial hypertension treated with multiple antihypertensives J Sex Med. 2 2005 856 864
15. J.S. Jaffe, M.R. Antell, M. Greenstein, P.C. Ginsberg, J.H. Mydlo, and R.C. Harkaway Use of intraurethral alprostadil in patients not responding to sildenafil citrate Urology 63 2004 951 954
16. O. Canvungen, W. Fredriksson, D. Bock, and A.L. Burnett Combination of vacuum erection device and PDE5 inhibitors as salvage therapy in PDE5 inhibitor nonresponders with erectile dysfunction J Sex Med. 6 2009 2561 2567
17. R. Raina, K.C. Nandipati, A. Agarwal, D. Mansour, D.C. Kaelber, and C.D. Zippe Combination therapy: Medicated uretrhral system for erection enhances sexual satisfaction in sildenafil citrate failure following nerve-sparing radical prostatectomy J Androl. 26 2005 757 760
18. J.H. Mydlo, M.A. Volpe, and R.J. MacChia Results from different patient populations using combined therapy with alprostadil and sildenafil: Predictors of satisfaction BJU Int. 86 2000 469 473
19. A. Nehra, M.L. Blute, D.M. Barret, and R.B. Moreland Rationale for combination therapy of intraurethral prostaglandin E(1) and sildenafil in the salvage of erectile dysfunction patients desiring noninvasive therapy Int J Impot Res. 4 2002 S38 S42
20. I. Gruenwald, B. Appel, and Y. Vardi Low-intensity extracorporeal shock wave therapy-a novel effective treatment for erectile dysfunction in severe ED patients who respond poorly to PDE5 inhibitor therapy J Sex Med. 9 2012 259 264
21. C.H. Yee, E.S. Chan, S.S. Hou, and C.F. Ng Extracorporeal shockwave therapy in the treatment of erectile dysfunction: A prospective, randomized, double-blinded, placebo controlled study Int J Urol. 21 2014 1041 1045
22. H. Padma-Natham Treatment of men with erectile dysfunction with transurethral alprostadil N Engl J Med. 336 1997 1 7
23. R.A. Costabile, M. Spevak, I.J. Fishman, F.E. Govier, W.J. Hellstrom, R. Shabsigh, and et al. Efficacy and safety of transuretral alprostadil in patients with erectile dysfunction following radical prostatectomy J Urol 160 1998 1325 1328
24. R. Raina, A. Agarwal, C.E. Zaramo, S. Ausmundson, D. Mansour, and C.D. Zippe Long-term efficacy and compliance of MUSE for erectile dysfunction following radical prostatectomy: SHIM (IIEF-5) analysis Int J Impot Res. 17 2005 86 90
25. G. Williams, C.C. Abbou, E.T. Amar, P. Desvaux, T.A. Flam, and G.A. Lycklama à Nijeholt Efficacy and safety of transurethral alprostadil therapy in men with erectile dysfunction Br J Urol. 81 1998 889 894
26. G. Rastrelli, G. Corona, M. Monami, C. Melani, D. Balzi, A. Sforza, and et al. Poor response to alprostadil ICI test is associated with arteriogenic erectile dysfunction and higher risk of major adverse cardiovascular events J Sex Med. 8 2011 3433 3445