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Volumn 44, Issue 2, 2016, Pages 377-385

Homing to solid cancers: A vascular checkpoint in adoptive cell therapy using CAR T-cells

Author keywords

Chemokine receptors; Endothelial cell anergy; Extravasation; High endothelial venules; Homing; Integrins; Selectins; Tumour blood vessels; Tumouricidal T lymphocytes; Vessel normalization

Indexed keywords

CHIMERIC PROTEIN; INTERLEUKIN 33; RECEPTOR ANTIBODY;

EID: 85009841550     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20150254     Document Type: Review
Times cited : (54)

References (60)
  • 2
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: Impact on clinical outcome
    • Fridman, W.H., Pages, F., Sautes-Fridman, C. and Galon, J. (2012) The immune contexture in human tumours: impact on clinical outcome. Nat. Rev. Cancer 12, 298-306
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3    Galon, J.4
  • 3
    • 80052236068 scopus 로고    scopus 로고
    • Human solid tumors contain high endothelial venules: Association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer
    • Martinet, L., Garrido, I., Filleron, T., Le Guellec, S., Bellard, E., Fournie, J.J., Rochaix, P. and Girard, J.P. (2011) Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer. Cancer Res. 71, 5678-5687
    • (2011) Cancer Res. , vol.71 , pp. 5678-5687
    • Martinet, L.1    Garrido, I.2    Filleron, T.3    Le Guellec, S.4    Bellard, E.5    Fournie, J.J.6    Rochaix, P.7    Girard, J.P.8
  • 7
    • 80051775476 scopus 로고    scopus 로고
    • T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
    • Kalos, M., Levine, B.L., Porter, D.L., Katz, S., Grupp, S.A., Bagg, A. and June, C.H. (2011) T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci. Transl. Med. 3, 95ra73
    • (2011) Sci. Transl. Med. , vol.3
    • Kalos, M.1    Levine, B.L.2    Porter, D.L.3    Katz, S.4    Grupp, S.A.5    Bagg, A.6    June, C.H.7
  • 8
    • 80455179612 scopus 로고    scopus 로고
    • Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
    • Brentjens, R.J., Riviere, I., Park, J.H., Davila, M.L., Wang, X., Stefanski, J., Taylor, C., Yeh, R., Bartido, S., Borquez-Ojeda, O. et al. (2011) Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 118, 4817-4828
    • (2011) Blood , vol.118 , pp. 4817-4828
    • Brentjens, R.J.1    Riviere, I.2    Park, J.H.3    Davila, M.L.4    Wang, X.5    Stefanski, J.6    Taylor, C.7    Yeh, R.8    Bartido, S.9    Borquez-Ojeda, O.10
  • 10
    • 30044447736 scopus 로고    scopus 로고
    • Immune cell migration in inflammation: Present and future therapeutic targets
    • Luster, A.D., Alon, R. and von Andrian, U.H. (2005) Immune cell migration in inflammation: present and future therapeutic targets. Nat. Immunol. 6, 1182-1190
    • (2005) Nat. Immunol. , vol.6 , pp. 1182-1190
    • Luster, A.D.1    Alon, R.2    Von Andrian, U.H.3
  • 11
    • 84876910443 scopus 로고    scopus 로고
    • The integration of T cell migration, differentiation and function
    • Masopust, D. and Schenkel, J.M. (2013) The integration of T cell migration, differentiation and function. Nat. Rev. Immunol. 13, 309-320
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 309-320
    • Masopust, D.1    Schenkel, J.M.2
  • 12
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt, R.L., Khoruts, A., Merica, R., Zell, T. and Jenkins, M.K. (2001) Visualizing the generation of memory CD4 T cells in the whole body. Nature 410, 101-105
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 13
    • 34250351311 scopus 로고    scopus 로고
    • Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation
    • Agrewala, J.N., Brown, D.M., Lepak, N.M., Duso, D., Huston, G. and Swain, S.L. (2007) Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation. J. Biol. Chem. 282, 6106-6115
    • (2007) J. Biol. Chem. , vol.282 , pp. 6106-6115
    • Agrewala, J.N.1    Brown, D.M.2    Lepak, N.M.3    Duso, D.4    Huston, G.5    Swain, S.L.6
  • 14
    • 84918506186 scopus 로고    scopus 로고
    • Tissue-resident memory T cells
    • Schenkel, J.M. and Masopust, D. (2014) Tissue-resident memory T cells. Immunity 41, 886-897
    • (2014) Immunity , vol.41 , pp. 886-897
    • Schenkel, J.M.1    Masopust, D.2
  • 15
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • Masopust, D., Vezys, V., Marzo, A.L. and Lefrancois, L. (2001) Preferential localization of effector memory cells in nonlymphoid tissue. Science 291, 2413-2417
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrancois, L.4
  • 16
  • 18
    • 82955207713 scopus 로고    scopus 로고
    • High endothelial venules as traffic control points maintaining lymphocyte population homeostasis in lymph nodes
    • Mionnet, C., Sanos, S.L., Mondor, I., Jorquera, A., Laugier, J.P., Germain, R.N. and Bajenoff, M. (2011) High endothelial venules as traffic control points maintaining lymphocyte population homeostasis in lymph nodes. Blood 118, 6115-6122
    • (2011) Blood , vol.118 , pp. 6115-6122
    • Mionnet, C.1    Sanos, S.L.2    Mondor, I.3    Jorquera, A.4    Laugier, J.P.5    Germain, R.N.6    Bajenoff, M.7
  • 19
    • 84944463669 scopus 로고    scopus 로고
    • Understanding high endothelial venules: Lessons for cancer immunology
    • Ager, A. and May, M.J. (2015) Understanding high endothelial venules: lessons for cancer immunology. Oncoimmunology 4, e1008791
    • (2015) Oncoimmunology , vol.4 , pp. e1008791
    • Ager, A.1    May, M.J.2
  • 21
  • 23
    • 84884270606 scopus 로고    scopus 로고
    • Expression of leukotriene B(4) receptor-1 on CD8(+) T cells is required for their migration into tumors to elicit effective antitumor immunity
    • Sharma, R.K., Chheda, Z., Jala, V.R. and Haribabu, B. (2013) Expression of leukotriene B(4) receptor-1 on CD8(+) T cells is required for their migration into tumors to elicit effective antitumor immunity. J. Immunol. 191, 3462-3470
    • (2013) J. Immunol. , vol.191 , pp. 3462-3470
    • Sharma, R.K.1    Chheda, Z.2    Jala, V.R.3    Haribabu, B.4
  • 25
    • 84929379918 scopus 로고    scopus 로고
    • Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity
    • Peske, J.D., Thompson, E.D., Gemta, L., Baylis, R.A., Fu, Y.X. and Engelhard, V.H. (2015) Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity. Nat. Commun. 6, 7114
    • (2015) Nat. Commun. , vol.6 , pp. 7114
    • Peske, J.D.1    Thompson, E.D.2    Gemta, L.3    Baylis, R.A.4    Fu, Y.X.5    Engelhard, V.H.6
  • 26
    • 77958063691 scopus 로고    scopus 로고
    • Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b
    • Craddock, J.A., Lu, A., Bear, A., Pule, M., Brenner, M.K., Rooney, C.M. and Foster, A.E. (2010) Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J. Immunother. 33, 780-788
    • (2010) J. Immunother. , vol.33 , pp. 780-788
    • Craddock, J.A.1    Lu, A.2    Bear, A.3    Pule, M.4    Brenner, M.K.5    Rooney, C.M.6    Foster, A.E.7
  • 27
    • 79960403269 scopus 로고    scopus 로고
    • Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor
    • Moon, E.K., Carpenito, C., Sun, J., Wang, L.C., Kapoor, V., Predina, J., Powell, Jr, D.J., Riley, J.L., June, C.H. and Albelda, S.M. (2011) Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor. Clin. Cancer Res. 17, 4719-4730
    • (2011) Clin. Cancer Res. , vol.17 , pp. 4719-4730
    • Moon, E.K.1    Carpenito, C.2    Sun, J.3    Wang, L.C.4    Kapoor, V.5    Predina, J.6    Powell, D.J.7    Riley, J.L.8    June, C.H.9    Albelda, S.M.10
  • 28
    • 0028840528 scopus 로고
    • Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: Effect of tumor type, transplantation site, and host strain
    • Fukumura, D., Salehi, H.A., Witwer, B., Tuma, R.F., Melder, R.J. and Jain, R.K. (1995) Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain. Cancer Res. 55, 4824-4829
    • (1995) Cancer Res. , vol.55 , pp. 4824-4829
    • Fukumura, D.1    Salehi, H.A.2    Witwer, B.3    Tuma, R.F.4    Melder, R.J.5    Jain, R.K.6
  • 29
    • 0036202346 scopus 로고    scopus 로고
    • Leukocyte recruitment in colon cancer: Role of cell adhesion molecules, nitric oxide, and transforming growth factor beta1
    • Bessa, X., Elizalde, J.I., Mitjans, F., Pinol, V., Miquel, R., Panes, J., Piulats, J., Pique, J.M. and Castells, A. (2002) Leukocyte recruitment in colon cancer: role of cell adhesion molecules, nitric oxide, and transforming growth factor beta1. Gastroenterology 122, 1122-1132
    • (2002) Gastroenterology , vol.122 , pp. 1122-1132
    • Bessa, X.1    Elizalde, J.I.2    Mitjans, F.3    Pinol, V.4    Miquel, R.5    Panes, J.6    Piulats, J.7    Pique, J.M.8    Castells, A.9
  • 30
    • 84928771999 scopus 로고    scopus 로고
    • T cell exclusion, immune privilege, and the tumor microenvironment
    • Joyce, J.A. and Fearon, D.T. (2015) T cell exclusion, immune privilege, and the tumor microenvironment. Science 348, 74-80
    • (2015) Science , vol.348 , pp. 74-80
    • Joyce, J.A.1    Fearon, D.T.2
  • 34
    • 0027362131 scopus 로고
    • Expression of adhesion molecules on the endothelium of normal tissue vessels and vascular tumors
    • Kuzu, I., Bicknell, R., Fletcher, C.D. and Gatter, K.C. (1993) Expression of adhesion molecules on the endothelium of normal tissue vessels and vascular tumors. Lab. Invest. 69, 322-328
    • (1993) Lab. Invest. , vol.69 , pp. 322-328
    • Kuzu, I.1    Bicknell, R.2    Fletcher, C.D.3    Gatter, K.C.4
  • 36
    • 33847137354 scopus 로고    scopus 로고
    • In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor
    • Boissonnas, A., Fetler, L., Zeelenberg, I.S., Hugues, S. and Amigorena, S. (2007) In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor. J. Exp. Med. 204, 345-356
    • (2007) J. Exp. Med. , vol.204 , pp. 345-356
    • Boissonnas, A.1    Fetler, L.2    Zeelenberg, I.S.3    Hugues, S.4    Amigorena, S.5
  • 39
    • 0028181372 scopus 로고
    • Localization of 111indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response
    • Pockaj, B.A., Sherry, R.M., Wei, J.P., Yannelli, J.R., Carter, C.S., Leitman, S.F., Carasquillo, J.A., Steinberg, S.M., Rosenberg, S.A. and Yang, J.C. (1994) Localization of 111indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response. Cancer 73, 1731-1737
    • (1994) Cancer , vol.73 , pp. 1731-1737
    • Pockaj, B.A.1    Sherry, R.M.2    Wei, J.P.3    Yannelli, J.R.4    Carter, C.S.5    Leitman, S.F.6    Carasquillo, J.A.7    Steinberg, S.M.8    Rosenberg, S.A.9    Yang, J.C.10
  • 47
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman, J. (1971) Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 285, 1182-1186
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 51
    • 77955406159 scopus 로고    scopus 로고
    • Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer
    • Shrimali, R.K., Yu, Z., Theoret, M.R., Chinnasamy, D., Restifo, N.P. and Rosenberg, S.A. (2010) Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer. Cancer Res. 70, 6171-6180
    • (2010) Cancer Res. , vol.70 , pp. 6171-6180
    • Shrimali, R.K.1    Yu, Z.2    Theoret, M.R.3    Chinnasamy, D.4    Restifo, N.P.5    Rosenberg, S.A.6
  • 52
    • 78649557780 scopus 로고    scopus 로고
    • Efficient Treg depletion induces T-cell infiltration and rejection of large tumors
    • Li, X., Kostareli, E., Suffner, J., Garbi, N. and Hammerling, G.J. (2010) Efficient Treg depletion induces T-cell infiltration and rejection of large tumors. Eur. J. Immunol. 40, 3325-3335
    • (2010) Eur. J. Immunol. , vol.40 , pp. 3325-3335
    • Li, X.1    Kostareli, E.2    Suffner, J.3    Garbi, N.4    Hammerling, G.J.5
  • 53
    • 84861215805 scopus 로고    scopus 로고
    • Tumor-targeted TNFalpha stabilizes tumor vessels and enhances active immunotherapy
    • Johansson, A., Hamzah, J., Payne, C.J. and Ganss, R. (2012) Tumor-targeted TNFalpha stabilizes tumor vessels and enhances active immunotherapy. Proc. Natl. Acad. Sci. U.S.A. 109, 7841-7846
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 7841-7846
    • Johansson, A.1    Hamzah, J.2    Payne, C.J.3    Ganss, R.4
  • 54
    • 84857829255 scopus 로고    scopus 로고
    • Targeting TNF-alpha to neoangiogenic vessels enhances lymphocyte infiltration in tumors and increases the therapeutic potential of immunotherapy
    • Calcinotto, A., Grioni, M., Jachetti, E., Curnis, F., Mondino, A., Parmiani, G., Corti, A. and Bellone, M. (2012) Targeting TNF-alpha to neoangiogenic vessels enhances lymphocyte infiltration in tumors and increases the therapeutic potential of immunotherapy. J. Immunol. 188, 2687-2694
    • (2012) J. Immunol. , vol.188 , pp. 2687-2694
    • Calcinotto, A.1    Grioni, M.2    Jachetti, E.3    Curnis, F.4    Mondino, A.5    Parmiani, G.6    Corti, A.7    Bellone, M.8
  • 55
    • 84929965822 scopus 로고    scopus 로고
    • Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8(+) T cells
    • Carretero, R., Sektioglu, I.M., Garbi, N., Salgado, O.C., Beckhove, P. and Hammerling, G.J. (2015) Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8(+) T cells. Nat. Immunol. 16, 609-617
    • (2015) Nat. Immunol. , vol.16 , pp. 609-617
    • Carretero, R.1    Sektioglu, I.M.2    Garbi, N.3    Salgado, O.C.4    Beckhove, P.5    Hammerling, G.J.6
  • 56
    • 0036494443 scopus 로고    scopus 로고
    • Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication
    • Ganss, R., Ryschich, E., Klar, E., Arnold, B. and Hammerling, G.J. (2002) Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer Res. 62, 1462-1470
    • (2002) Cancer Res. , vol.62 , pp. 1462-1470
    • Ganss, R.1    Ryschich, E.2    Klar, E.3    Arnold, B.4    Hammerling, G.J.5
  • 57
    • 2442452552 scopus 로고    scopus 로고
    • CpG motifs as proinflammatory factors render autochthonous tumors permissive for infiltration and destruction
    • Garbi, N., Arnold, B., Gordon, S., Hammerling, G.J. and Ganss, R. (2004) CpG motifs as proinflammatory factors render autochthonous tumors permissive for infiltration and destruction. J. Immunol. 172, 5861-5869
    • (2004) J. Immunol. , vol.172 , pp. 5861-5869
    • Garbi, N.1    Arnold, B.2    Gordon, S.3    Hammerling, G.J.4    Ganss, R.5
  • 60
    • 84877586473 scopus 로고    scopus 로고
    • Endothelial cell-specific lymphotoxin-beta receptor signaling is critical for lymph node and high endothelial venule formation
    • Onder, L., Danuser, R., Scandella, E., Firner, S., Chai, Q., Hehlgans, T., Stein, J.V. and Ludewig, B. (2013) Endothelial cell-specific lymphotoxin-beta receptor signaling is critical for lymph node and high endothelial venule formation. J. Exp. Med. 210, 465-473
    • (2013) J. Exp. Med. , vol.210 , pp. 465-473
    • Onder, L.1    Danuser, R.2    Scandella, E.3    Firner, S.4    Chai, Q.5    Hehlgans, T.6    Stein, J.V.7    Ludewig, B.8


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