Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands

Developmental Cell

Volumn 40, Issue 2, 2017, Pages 193-201

  Kakuda, Shinako ^a   Haltiwanger, Robert S ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

development; EGF repeats; Fringe; glycosylation; Notch; O fucose; signal transduction

Indexed keywords

EPIDERMAL GROWTH FACTOR; FRINGE PROTEIN; FUCOSE; N ACETYLGLUCOSAMINYLTRANSFERASE; NOTCH1 RECEPTOR; PROTEIN JAGGED 1; UNCLASSIFIED DRUG; DLK1 PROTEIN, MOUSE; GLYCOSYLTRANSFERASE; LFNG PROTEIN, MOUSE; LIGAND; MFNG PROTEIN, MOUSE; PROTEIN; PROTEIN BINDING; RFNG PROTEIN, MOUSE; SIGNAL PEPTIDE;

ARTICLE; BINDING SITE; ENZYME ACTIVATION; GLYCOSYLATION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOICHIOMETRY; TRANSCRIPTION REGULATION; AMINO ACID REPEAT; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; HEK293 CELL LINE; HUMAN; METABOLISM; MOUSE; NIH 3T3 CELL LINE;

AMINO ACID SEQUENCE; ANIMALS; EPIDERMAL GROWTH FACTOR; FUCOSE; GLYCOSYLTRANSFERASES; HEK293 CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JAGGED-1 PROTEIN; LIGANDS; MICE; MODELS, BIOLOGICAL; NIH 3T3 CELLS; PROTEIN BINDING; PROTEINS; RECEPTOR, NOTCH1; REPETITIVE SEQUENCES, AMINO ACID;

EID: 85009802398     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2016.12.013     Document Type: Article

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